Chirocaine
Chirocaine Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Chirocaine is a brand name. Its generic name is Levobupivacaine.
Chirocaine
Chirocaine is a medication used for local anesthesia to prevent pain during minor surgeries and procedures. It is a long-acting amide-type local anesthetic, and is chemically similar to bupivacaine. This medication can be used for epidural, nerve block, infiltration, and regional analgesia.
Uses
Chirocaine is primarily used for local anesthesia to prevent pain during minor surgeries and procedures. It is also used in epidural, nerve block, infiltration, and regional analgesia.
Mechanism of Action
Chirocaine works by blocking nerve signals from reaching the brain and spinal cord, resulting in a loss of sensation in the affected area. It also temporarily interferes with the conduction of pain signals, which reduces sensation and pain.
How Long Does it Take to Work?
Chirocaine typically takes effect within 5-10 minutes. The duration of effectiveness can last up to 8 hours in some patients.
Absorption
Chirocaine is rapidly absorbed from the injection site and distributed into the tissues. It is metabolized in the liver and excreted via the kidneys.
Route of Elimination
Chirocaine is eliminated via the kidneys and is metabolized by the liver.
Dosage
Chirocaine dosages depend on the type of procedure being performed, the patient's age, weight, health condition, and other factors. The usual adult dose is 0.5-1 mg/kg of body weight for infiltration anesthesia, as well as nerve block and epidural anesthesia. For regional analgesia, the typical dose is 0.125-1 mg/kg of body weight.
Administration
Chirocaine is administered via injection into the affected area. It is important to follow the instruction of the doctor, nurse, or other healthcare professional while using this medication.
Side Effect
Common side effects of levobupivacaine include dizziness, lightheadedness, nausea, vomiting, headache, muscle twitching, blurred vision, ringing in the ears, and confusion. Less common side effects include seizure, seizures, and irregular heart rhythm. In rare cases, the medication may also cause an allergic reaction.
Toxicity
Chirocaine is considered to be a moderately toxic medication when taken in higher doses than recommended. If the medication is accidentally injected into an artery, nerve, or other sensitive tissue, it can cause significant tissue damage or tissue death.
Precautions
It is important to tell the doctor about any allergies or medical conditions prior to receiving levobupivacaine. This medication should not be used if the patient is hypersensitive to bupivacaine, lidocaine, or local anesthetics of the amide type.
Interactions
Chirocaine may interact with other medications, such as diuretics, anticoagulants, digoxin, or antidepressives. It is important to tell the doctor about any other medications that are being taken prior to receiving Chirocaine.
Disease Interaction
Chirocaine should be used with caution in patients with certain medical conditions, such as epilepsy, epilepsy, impaired renal or liver function, cardiovascular disease, or severe hyervasive or chronic pain conditions.
Drug Interactions
Chirocaine may interact with diuretics, anticoagulants, digoxin, or antidepressants. It is important to tell the doctor about any other medications that are being taken prior to receiving Chirocaine.
Food Interactions
There are no known food interactions for Chirocaine.
Pregnancy Use
Chirocaine should not be used during pregnancy unless the potential benefit justifies the potential risk to the unborn baby. It is important to talk to the doctor before using this medication while pregnant.
Lactation Use
Chirocaine is not recommended to be used during lactation. If the medication is necessary, the patient should use extreme caution while breastfeeding.
Acute Overdose
An acute overdose of levobupivacaine may result in the following symptoms: dizziness, weakness, drowsiness, sedation, difficult or labored breathing, fainting, irregular heartbeat, seizures, and coma. In case of an overdose, seek prompt medical attention.
Contraindication
Chirocaine should not be used if the patient is hypersensitive to bupivacaine, lidocaine, or local anesthetics of the amide type.
Use Direction
Chirocaine should only be used as directed by a healthcare professional. It is important to follow the instructions and directions of the doctor while using this medication.
Storage Condition
Chirocaine should be stored at room temperature in a dry and dark place. It should be kept away from moisture and heat.
Volume of Distribution
Chirocaine has a volume of distribution of 3 to 6 liters in adults. It is strong bound to plasma proteins.
Half Life
Chirocaine has a half-life of about 2 to 3 hours in adults.
Clearance
Chirocaine has an average total clearance of about 1.6 liters per hour in adults.
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