Cefuxime

Cefuxime Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Cefuxime is a brand name. Its generic name is Cefuroxime.

Introduction

Cefuxime is an antibiotic of the cephalosporin class used to treat a variety of bacterial infections. It can be used to treat a wide range of infections including skin and soft tissue infections, respiratory infections, urinary tract infections, sexually transmitted infections, and bone and joint infections.

Uses For

Cefuxime is used to treat a variety of bacterial infections, including skin and soft tissue infections, respiratory infections, urinary tract infections, sexually transmitted infections, and bone and joint infections.

Mechanism of Action

Cefuxime works by inhibiting the growth of bacteria by interfering with the bacterial cell wall synthesis. This prevents the bacteria from being able to replicate and leads to the eventual death of the bacteria.

How Long Does It Take To Work?

Cefuxime typically begins to work within 48 hours of taking it, and symptoms should improve during that time. It is important to finish the full course of medication to prevent the re-emergence of the infection. If symptoms have not improved after 48 hours, contact your doctor.

Absorption

Cefuxime is absorbed rapidly from the gastrointestinal tract and reaches peak concentrations in various organs and tissues, including the lungs, kidneys, prostate , and central nervous system.

Route of Elimination

Cefuxime is eliminated mainly via the kidneys. It is also metabolized in the liver and excreted in the bile.

Dosage

The dosage of cefuroxime varies according to the infection being treated and the patient's age and weight. Generally, it is given as a single dose or in two divided doses given every 12 hours. For adults, the dosage ranges from 125 mg to 500 mg taken orally every 8 to 12 hours. For children, the dosage may be lower. It is important to follow your doctor's instructions.

Administration

Cefuxime is usually taken orally. It can also be given intravenously, depending on the condition being treated. For oral administration, it is usually taken with a full glass of water. It can be taken with or without food.

Side Effect

Common side effects associated with cefuroxime include nausea, vomiting, stomach pain, diarrhea, headache, dizziness, rash, itching, and vaginal itching and discharge.

Toxicity

Cefuxime is generally safe and well tolerable at recommended doses. However, it can cause certain toxic side effects when taken in high doses, including seizures, tremors, coma, and death.

Precautions

Cefuxime should not be used in patients with a known allergy or hypersensitivity to cefuroxime, other cephalosporins, or penicillins. Cefuxime should be used with caution in patients with a history of liver or kidney disease, or in those who are pregnant or breastfeeding.

Interaction

Cefuxime can interact with other medications, including non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, warfarin (blood thinners), and certain antibiotics. Before taking cefuroxime, it is important to tell your doctor about any other medications you are taking to avoid potential interactions.

Disease Interactions

Cefuxime can interact with certain diseases that can affect its efficacy. These include certain liver and kidney disease, diseases of the immune system, and conditions that affect the gastrointestinal tract. It is important to tell your doctor if you have any of these conditions before taking cefuroxime.

Drug Interactions

Cefuxime can interact with certain medications, including other antibiotics, anticoagulants (blood thinners), nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin, and probenecid. It is important to tell your doctor about all medications you are taking.

Food Interactions

Cefuxime may interact with certain foods. It should be taken at least two hours before or after taking calcium, magnesium, or iron supplements or antacids. Also, avoid alcohol while taking cefuroxime.

Pregnancy Use

Cefuxime is generally safe to use during pregnancy, however, it should be used with caution and only when absolutely necessary. It is important to consult your doctor before taking cefuroxime during pregnancy.

Lactation Use

Cefuxime is usually safe to use during lactation, however, it should be used with caution and only when absolutely necessary. It is important to consult your doctor before taking cefuroxime while breastfeeding.

Acute Overdose

An overdose of cefuroxime can cause serious side effects, including convulsions, dizziness, loss of consciousness, and even coma in some cases. It is important to seek medical attention immediately if you think you or someone else has taken an overdose of cefuroxime.

Contraindication

Cefuxime is not to be used in patients with a known allergy or hypersensitivity to cefuroxime or other cephalosporins, or penicillins. Cefuxime should also not be used in patients with a history of liver or kidney disease.

Use Direction

Cefuxime should be taken as directed by your doctor. The dosage and frequency should not be exceeded or decreased without consulting your doctor. Taking cefuroxime with food or antacids can help reduce side effects.

Storage Condition

Cefuxime should be stored at room temperature, below 30°C (86°F). Keep it in a tightly closed container away from light, heat, and moisture.

Volume of Distribution

The volume of distribution of cefuroxime is about 0.4-0.5 L/Kg.

Half Life

Cefuxime has a half-life of 2-3 hours.

Clearance

Cefuxime is cleared from the body by both hepatic and renal pathways. The total clearance is 6.3 mL/min/kg.

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Some Frequently Asked Questions About Cefuxime

What is Cefuxime?

Cefuxime is an antibiotic used to treat a wide variety of infections caused by bacteria. It works by stopping the growth of bacteria. It is available in brand and generic form.

What is Cefuxime used to treat?

Cefuxime is indicated to treat bacterial infections, including upper and lower respiratory tract, urinary tract, skin, and soft tissue infections.

Does Cefuxime have side effects?

Cefuxime may cause side effects such as nausea, vomiting, diarrhea, headache, or dizziness.

Can Cefuxime be used to treat bronchitis?

Yes, Cefuxime is commonly used to treat infections caused by bronchitis.

Is Cefuxime a penicillin drug?

No, Cefuxime is not a penicillin drug. It is a cephalosporin antibiotic.

Is Cefuxime safe to use during pregnancy?

Cefuxime is generally considered safe to use during pregnancy. However, it is recommended to consult a doctor before using any medication during pregnancy.

What is the recommended dosage of Cefuxime?

The recommended dosage of Cefuxime depends on the severity of the infection. It is recommended to consult a doctor for the exact dosage.

Can Cefuxime be used in children?

Yes, Cefuxime can be used in children. However, the dosage may need to be adjusted according to the severity of the infection.

Can Cefuxime be taken with food?

Yes, Cefuxime can be taken with food. However, it is recommended to take the medication with a full glass of water.

Does Cefuxime cause weight gain?

No, Cefuxime does not cause weight gain. However, it is recommended to consult a doctor if any unusual symptom is observed.

Is Cefuxime an over the counter drug?

No, Cefuxime is not available as an over the counter drug. It is available with a doctor's prescription.

What is the shelf life of Cefuxime?

The shelf life of Cefuxime is two years when stored under proper conditions.

Can Cefuxime cause a yeast infection?

Yes, Cefuxime may cause a yeast infection as a side effect.

What are the common side effects of Cefuxime?

The common side effects of Cefuxime include nausea, vomiting, dizziness, headache, or diarrhea.

Can Cefuxime be used to treat a sinus infection?

Yes, Cefuxime is commonly used to treat a sinus infection.

What are the contraindications of Cefuxime?

Cefuxime should not be used in patients with hypersensitivity to cephalosporin, penicillin, or any other medication.

Can Cefuxime be taken long term?

Yes, Cefuxime can be taken long term under the supervision of a doctor.

Can Cefuxime be used to treat a urinary tract infection?

Yes, Cefuxime is commonly used to treat a urinary tract infection.

Does Cefuxime cause headache?

Yes, Cefuxime may cause a headache as a side effect.

Can Cefuxime be used to treat an ear infection?

Yes, Cefuxime is commonly used to treat an ear infection.

What should be avoided while taking Cefuxime?

Alcohol and grapefruit should be avoided while taking Cefuxime.

What is the generic name of Cefuxime?

The generic name of Cefuxime is cefuroxime axetil.

Can Cefuxime be used to treat pneumonia?

Yes, Cefuxime can be used to treat pneumonia.

What are the pharmacological actions of Cefuxime?

Cefuxime has antibacterial, anti-inflammatory, and immunomodulatory actions.

What is the dose of Cefuxime for adults?

The dose of Cefuxime for adults is 250mg-500mg twice daily.

Can Cefuxime be used to treat an STD?

Yes, Cefuxime can be used to treat some Sexually Transmitted Diseases.

Does Cefuxime interact with other medications?

Yes, Cefuxime may interact with other medications such as aspirin and ibuprofen.

Can Cefuxime cause diarrhea?

Yes, Cefuxime may cause diarrhea as a side effect.

How long does it take for Cefuxime to work?

It can take up to several days for Cefuxime to start working. However, the exact time depends on the severity of the infection.

Does Cefuxime cause drowsiness?

Yes, Cefuxime may cause drowsiness as a side effect.

How is Cefuxime administered?

Cefuxime is administered orally in tablet or capsule form.

Can Cefuxime be used to treat a strep throat?

Yes, Cefuxime is commonly used to treat a strep throat.

Does Cefuxime cause stomach upset?

Yes, Cefuxime may cause stomach upset as a side effect.

Does Cefuxime treat UTI?

Yes, Cefuxime is commonly used to treat UTI (Urinary Tract Infection).

What is the dosage of Cefuxime for children?

The dosage of Cefuxime for children depends on the age and weight of the child. It is recommended to consult a doctor for the exact dosage.

Is Cefuxime an antibiotic?

Yes, Cefuxime is an antibiotic used to treat a wide variety of bacterial infections.

Is Cefuxime effective against staphylococcus aureus?

Yes, Cefuxime is effective against staphylococcus aureus.

What is the usual duration of treatment for Cefuxime?

The usual duration of treatment with Cefuxime is 5-7 days.

Does Cefuxime have an expiration date?

Yes, Cefuxime has an expiration date. It is recommended to check the expiration date before using the medication.

Can Cefuxime be used to treat a sinus infection?

Yes, Cefuxime is commonly used to treat a sinus infection.

Is Cefuxime an over the counter drug?

No, Cefuxime is not available as an over the counter drug. It is available with a doctor's prescription.