Ceftibutene
Ceftibutene Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Ceftibutene is a brand name. Its generic name is Ceftibuten.
Introduction
Ceftibutene (brand name CEDAX) is a third-generation cephalosporin antibiotic, an antibiotic used to treat a variety of bacterial infections. Ceftibutene is usually prescribed to treat bacterial infections such as bronchitis, sinusitis, urinary tract infections, and skin infections including abscesses, boils, and infected wounds.Uses for
Ceftibutene is used to treat a variety of bacterial infections including bronchitis, sinusitis, urinary tract infections, and skin infections including abscesses, boils, and infected wounds. Ceftibutene is also used to prevent certain infections in people with weakened immune systems.Mechanism Of Action
Ceftibutene works by targeting and destroying bacteria and stopping them from reproducing and spreading. The antibiotic works by inhibiting bacterial cell wall synthesis, preventing bacteria from forming the protective outer layer that is essential for their survival. Ceftibutene also interferes with bacterial DNA replication, preventing bacteria from reproducing.How Long Does It Take to Work?
Ceftibutene typically takes 24-48 hours before it begins to take effect, depending on the severity of the infection. Most people see improvement in their symptoms within a few days once the antibiotic has taken effect.Absorption
Ceftibutene is rapidly and completely absorbed after oral administration, reaching maximum plasma levels within 1-2 hours. The drug has an absolute bioavailability of 100%, meaning that all of the drug is absorbed and utilized by the body.Route of Elimination
Ceftibutene is eliminated primarily by the kidneys, with up to 80% of the drug being excreted unchanged in the urine within 24 hours after administration.Dosage
The dosage of Ceftibutene will vary based on the type and severity of the infection being treated. Typical doses for adults range from 400 mg once a day to 600 mg every 12 hours. The total daily dose should not exceed 1.2 grams.Administration
Ceftibutene is administered orally and is available as a tablet, liquid, and granules for suspension. It should be taken with food or a full glass of water to reduce the risk of stomach upset.Side Effects
Common side effects of Ceftibutene include nausea, vomiting, diarrhoea, abdominal pain, and headache. It can also cause hypersensitivity reactions such as rash and itching.Toxicity
Ceftibutene is generally well tolerated, though high doses can cause kidney damage. Overdoses of Ceftibutene can cause significant falls in blood pressure and can be fatal.Precaution
Ceftibutene should not be used by people who are allergic to any of the ingredients in the drug. It should also not be used by pregnant women or women who are breastfeeding.Interaction
Ceftibutene may interact with other drugs, including diuretics, NSAIDs, oral contraceptives, and blood thinners. It may also interact with certain foods, such as milk, cheese, and yogurt.Disease Interaction
Ceftibutene should not be used in people who have an infection caused by penicillin-resistant bacteria. It may also reduce the effectiveness of certain vaccines.Drug Interaction
Ceftibutene may interact with other drugs, including diuretics, NSAIDs, oral contraceptives, and blood thinners.Food Interactions
Ceftibutene may interact with certain foods, such as milk, cheese, and yogurt. It is important to avoid these foods while taking Ceftibutene.Pregnancy Use
Ceftibutene is not recommended for use by pregnant women.Lactation Use
Ceftibutene should not be used by women who are breastfeeding.Acute Overdose
An overdose of Ceftibutene can cause significant drops in blood pressure and can be fatal. In such cases, the patient should seek immediate medical attention.Contraindication
Ceftibutene should not be used by people who are allergic to any of the ingredients in the drug.Use Direction
Ceftibutene should be taken at the same time each day, with or without food. It is important to take the full amount of medication prescribed by the doctor, even if symptoms improve.Storage Condition
Ceftibutene should be stored at room temperature, away from direct sunlight and moisture. It should be kept in a tightly sealed container.Volume Of Distribution
Ceftibutene has an apparent volume of distribution of 0.22-0.37 L/kg.Half-Life
The half-life of ceftibuten is 2.7-3.9 hours.Clearance
Ceftibutene has a clearance of 0.2-0.3 L/hr/kg.Here you find in details version of Ceftibutene
Some Frequently Asked Questions About Ceftibutene
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