Cefonic

Cefonic Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Cefonic is a brand name. Its generic name is Cefpodoxime.

Introduction

Cefonic (also referred to as cefpodoxime proxetil) is an antibiotic used to treat sinus infections, bronchitis, pneumonia, ENT infections, skin infections, and certain urinary tract infections. The drug belongs to a class of antibiotics called cephalosporins and is produced in oral, and intravenous formats.

Uses

Cefonic is used to treat a variety of bacterial infections such as sinusitis, bronchitis, pneumonia, otitis media, cellulitis, urinary tract infections, skin and skin structure infections, and pharyngitis/tonsillitis.

Mechanism of Action

Cefonic works by inhibiting bacterial cell wall synthesis. This leads to an influx of water and causes the cell wall to rupture, thus killing the bacteria. In addition, the drug has some activity against certain types of fungi, viruses and protozoa.

How Long Does It Take to Work

Cefonic usually begins to take effect within 1-2 days of administration. However, it may take up to 5-7 days to experience full relief of symptoms.

Absorption, Route of Elimination, Dosage and Administration

Cefonic is rapidly and almost completely absorbed from the gastrointestinal tract. The drug is eliminated primarily through the kidneys and the excretion rate is slow. The usual adult dosage for oral administration ranges from 200 to 400 mg, taken every 12 hours. Oral suspension formulations are available in 50 and 100 mg/5 mL strengths.

Side Effects

Common side effects of cefpodoxime include diarrhea, nausea, vomiting, abdominal pain, dizziness, headache, fatigue, rash, and skin sensitivity. Severe side effects include anaphylaxis, kidney damage, and fainting. Cefonic can also cause abnormal liver function test results and thrombocytopenia.

Toxicity

Cefonic is generally well-tolerated. Overdose symptoms include nausea, vomiting, diarrhea, dizziness, rapid heart rate, and rare seizures.

Precautions

Cefonic should be avoided in patients with history of allergy to cephalosporins. The drug should not be used in patients with impaired kidney or liver function. It should also be used with caution in pregnant and breastfeeding women.

Interaction

Cefonic may interact with other medications such as antacids, warfarin, digoxin, probenecid, and certain drugs for HIV/AIDS, etc. Drugs that interact with cefpodoxime include: paroxetine; phenytoin; ritonavir; certain fluoroquinolone antibiotics such as ciprofloxacin, norfloxacin, and ofloxacin; and certain anti-seizure drugs such as phenytoin, valproic acid, and carbamazepine.

Disease Interaction

Cefonic may interact with certain medical conditions such as kidney disease, history of allergic reactions to other cephalosporin antibiotics, and intestinal inflammation due to infection or the use of antibiotics. Cefonic should be used with caution in patients with kidney disease. It should not be used in patients if there is an existing intestine infection or if the patient has recently been taking antibiotics.

Drug Interaction

Drug interactions may occur when cefpodoxime is taken with other medications such as antacids, warfarin, probenecid, and certain HIV drugs. Cefonic should not be used together with drugs like paroxetine, phenytoin, ritonavir, certain fluoroquinolone antibiotics (ciprofloxacin, norfloxacin, ofloxacin), certain anti-seizure drugs (phenytoin, valproic acid, carbamazepine), etc. Patients should inform their physicians of any medications they are currently taking before taking cefpodoxime.

Food Interactions

Cefonic should be taken with a full glass of water. Food can decrease the absorption of cefpodoxime, so the drug should be taken at least 2 hours before or after a meal. Avoid consumption of dairy products, antacids, iron supplements, and vitamins within 2 hours of taking cefpodoxime.

Pregnancy Use

Cefonic is likely safe to use during pregnancy. However, it is best to consult a doctor before taking cefpodoxime during pregnancy.

Lactation Use

Cefonic is not known to be harmful when breastfeeding. However, it is best to consult a doctor before taking cefpodoxime while breastfeeding.

Acute Overdose

Acute overdose of cefpodoxime can result in nausea, dizziness, rapid heart rate, and seizures. Seek medical help if overdose is suspected.

Contraindication

Cefonic is contraindicated in patients with known allergy to cephalosporins.

Dosage Information

The usual adult dosage for oral administration ranges from 200 to 400 mg, taken every 12 hours.

Direction of Use

Cefonic should be taken orally with a full glass of water. It should be taken with or without food. It should not be taken with dairy products, antacids, iron supplements, or vitamins.

Storage Condition

Cefonic should be stored in a tight container, away from light and moisture, at room temperature (15-30°C).

Volume of Distribution

Cefonic has a volume of distribution of 0.3 - 0.5 L/kg.

Half-Life

The average half-life of cefpodoxime is about 2 - 4 hours.

Clearance

The average clearance of cefpodoxime is 50 - 70 mL/min.

Here you find in details version of Cefonic

Some Frequently Asked Questions About Cefonic

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What is Cefonic?

Cefonic is an antibiotic used to treat certain types of bacterial infections. It belongs to a class of antibiotics called cephalosporins that work by stopping the growth of bacteria.

What infections does Cefonic treat?

Cefonic is used to treat infections caused by certain bacteria, such as lower respiratory tract infections, otitis media (middle ear infections), skin infections, and urinary tract infections.

How does Cefonic work?

Cefonic works by attacking the bacteria that cause the infection. It works by interfering with the bacteria’s ability to make cell walls, which results in the death of the bacteria.

Who should take Cefonic?

Cefonic should be taken by those who have been prescribed it by a doctor to treat a bacterial infection. It should not be taken by anyone who has an allergy to cephalosporin antibiotics.

How do I take Cefonic?

Cefonic should be taken as directed by your doctor. The dosage and length of treatment will depend on the infection being treated. The tablets should be taken with a full glass of water. If you forget to take a dose, take it as soon as you remember.

What are the possible side effects of taking Cefonic?

Some common side effects of taking Cefonic may include nausea, vomiting, diarrhea, or skin rash. Serious side effects include easy bleeding or bruising, yellowing skin or eyes, chest pain, or difficulty breathing. Tell your doctor if you experience any of these side effects.

What if I am allergic to Cefonic?

If you are allergic to Cefonic or other cephalosporin antibiotics, do not take this drug. Tell your doctor about any allergies that you have before beginning treatment.

Can I take Cefonic with other medications?

Before taking Cefonic, tell your doctor if you are taking any other medications, especially probenecid, sulfamethoxazole, or valproic acid. Some medications may interact with Cefonic, so it is important to discuss them with your doctor before beginning treatment.

Can Cefonic be used to treat a viral infection?

No, Cefonic is not effective for treating viral infections since it only attacks bacterial infections.

What is the recommended dosage for Cefonic?

The recommended dosage of Cefonic depends on the infection being treated and on the patient's age and weight. It is important to follow your doctor's instructions when taking Cefonic.

Can Cefonic be used during pregnancy?

Cefonic is generally considered safe to use during pregnancy, but it is always best to consult your doctor before taking any medication during pregnancy.

Can I miss a dose of Cefonic?

If you miss a dose of Cefonic, take it as soon as possible. However, if it is close to the time for your next dose, skip the missed dose and continue with your normal schedule.

Is Cefonic safe for children?

Yes, Cefonic is safe to use in children. However, it is important to follow your doctor's instructions for dosage and duration of treatment.

Does Cefonic have any interactions with food?

No, Cefonic does not have any known food interactions.

Can I drink alcohol while taking Cefonic?

It is not recommended to drink alcohol while taking Cefonic, as it may increase the chance of side effects.

Does Cefonic cause headaches?

Cefonic can cause headaches as a side effect in some people. If you experience headaches while taking Cefonic, contact your doctor.

How long should I take Cefonic?

Your doctor will determine how long you should take Cefonic. It is important to follow your doctor’s instructions for the duration of treatment.

Can Cefonic affect the liver?

Cefonic can potentially cause liver damage in rare cases. If you notice any symptoms of liver damage, such as yellowing of the skin or eyes, contact your doctor.

What should I do if I develop an allergic reaction to Cefonic?

If you develop an allergic reaction while taking Cefonic, stop taking the medication and contact your doctor immediately.

Is Cefonic available as a generic drug?

Yes, Cefonic is available as a generic drug.

Does Cefonic cause drowsiness?

Cefonic can cause drowsiness as a side effect in some people. If you experience drowsiness while taking Cefonic, contact your doctor.

Can I take Cefonic with other antibiotics?

No, Cefonic should not be taken with other antibiotics since it can lead to increased side effects and altered effectiveness.

Can Cefonic treat sore throats?

No, Cefonic is not effective for treating sore throat caused by viral infections.

Can Cefonic be used to treat bacterial meningitis?

Yes, Cefonic can be used to treat bacterial meningitis.

Can Cefonic be used to treat strep throat?

Yes, Cefonic can be used to treat strep throat.

Is Cefonic available in other forms such as an oral suspension?

Yes, Cefonic is also available as an oral suspension.

Can I take Cefonic for a long period of time?

It is not recommended to take Cefonic for a long period of time, as it can lead to overgrowth of certain bacteria and lead to antibiotic resistance.

Can I take Cefonic with ibuprofen?

Yes, Cefonic can be taken with ibuprofen.

Is it safe to take Cefonic while breastfeeding?

It is not recommended to take Cefonic while breastfeeding because it can pass into breast milk and affect the infant. Contact your doctor before taking Cefonic while breastfeeding.

Can Cefonic be used to treat ear infections?

Yes, Cefonic can be used to treat ear infections.

Can Cefonic treat urinary tract infections?

Yes, Cefonic can be used to treat urinary tract infections.

Is Cefonic safe for people with kidney or liver disease?

People with kidney or liver disease should use Cefonic with caution, as it is broken down by the kidneys and liver. Talk to your doctor before taking Cefonic if you have kidney or liver disease.

Can Cefonic make you tired?

Yes, Cefonic can cause fatigue as a side effect in some people. Talk to your doctor if you experience fatigue while taking Cefonic.

How often do I need to take Cefonic?

You should take Cefonic as directed by your doctor. The frequency of doses will depend on the infection as well as the patient’s age and weight.

What laboratory tests should be done while taking Cefonic?

Your doctor may recommend certain laboratory tests such as a complete blood count, liver function tests, or kidney function tests while taking Cefonic.

Can Cefonic be used in animals such as cats or dogs?

Yes, Cefonic can be used in cats and dogs, but only under the direction of a veterinarian.

What should I do if I miss a dose of Cefonic?

If you miss a dose of Cefonic, take it as soon as possible. If it is close to the time for your next dose, skip the missed dose and continue on your regular schedule.

What can happen if I take an overdose of Cefonic?

If you take an overdose of Cefonic, contact your doctor or local poison control center immediately. Symptoms of an overdose may include nausea, dizziness, or difficulty breathing.

Should I avoid activities that require mental alertness while taking Cefonic?

Yes, it is best to avoid activities that require mental alertness while taking Cefonic because it can cause drowsiness and dizziness as side effects.

Can Cefonic cause nausea and vomiting?

Yes, Cefonic can cause nausea and vomiting as side effects. Talk to your doctor if you experience nausea and vomiting while taking Cefonic.