Cefgrace

Cefgrace Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Cefgrace is a brand name. Its generic name is Cefuroxime.

Introduction

Cefgrace is an antibiotic of the cephalosporin class used to treat a variety of bacterial infections. It can be used to treat a wide range of infections including skin and soft tissue infections, respiratory infections, urinary tract infections, sexually transmitted infections, and bone and joint infections.

Uses For

Cefgrace is used to treat a variety of bacterial infections, including skin and soft tissue infections, respiratory infections, urinary tract infections, sexually transmitted infections, and bone and joint infections.

Mechanism of Action

Cefgrace works by inhibiting the growth of bacteria by interfering with the bacterial cell wall synthesis. This prevents the bacteria from being able to replicate and leads to the eventual death of the bacteria.

How Long Does It Take To Work?

Cefgrace typically begins to work within 48 hours of taking it, and symptoms should improve during that time. It is important to finish the full course of medication to prevent the re-emergence of the infection. If symptoms have not improved after 48 hours, contact your doctor.

Absorption

Cefgrace is absorbed rapidly from the gastrointestinal tract and reaches peak concentrations in various organs and tissues, including the lungs, kidneys, prostate , and central nervous system.

Route of Elimination

Cefgrace is eliminated mainly via the kidneys. It is also metabolized in the liver and excreted in the bile.

Dosage

The dosage of cefuroxime varies according to the infection being treated and the patient's age and weight. Generally, it is given as a single dose or in two divided doses given every 12 hours. For adults, the dosage ranges from 125 mg to 500 mg taken orally every 8 to 12 hours. For children, the dosage may be lower. It is important to follow your doctor's instructions.

Administration

Cefgrace is usually taken orally. It can also be given intravenously, depending on the condition being treated. For oral administration, it is usually taken with a full glass of water. It can be taken with or without food.

Side Effect

Common side effects associated with cefuroxime include nausea, vomiting, stomach pain, diarrhea, headache, dizziness, rash, itching, and vaginal itching and discharge.

Toxicity

Cefgrace is generally safe and well tolerable at recommended doses. However, it can cause certain toxic side effects when taken in high doses, including seizures, tremors, coma, and death.

Precautions

Cefgrace should not be used in patients with a known allergy or hypersensitivity to cefuroxime, other cephalosporins, or penicillins. Cefgrace should be used with caution in patients with a history of liver or kidney disease, or in those who are pregnant or breastfeeding.

Interaction

Cefgrace can interact with other medications, including non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, warfarin (blood thinners), and certain antibiotics. Before taking cefuroxime, it is important to tell your doctor about any other medications you are taking to avoid potential interactions.

Disease Interactions

Cefgrace can interact with certain diseases that can affect its efficacy. These include certain liver and kidney disease, diseases of the immune system, and conditions that affect the gastrointestinal tract. It is important to tell your doctor if you have any of these conditions before taking cefuroxime.

Drug Interactions

Cefgrace can interact with certain medications, including other antibiotics, anticoagulants (blood thinners), nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin, and probenecid. It is important to tell your doctor about all medications you are taking.

Food Interactions

Cefgrace may interact with certain foods. It should be taken at least two hours before or after taking calcium, magnesium, or iron supplements or antacids. Also, avoid alcohol while taking cefuroxime.

Pregnancy Use

Cefgrace is generally safe to use during pregnancy, however, it should be used with caution and only when absolutely necessary. It is important to consult your doctor before taking cefuroxime during pregnancy.

Lactation Use

Cefgrace is usually safe to use during lactation, however, it should be used with caution and only when absolutely necessary. It is important to consult your doctor before taking cefuroxime while breastfeeding.

Acute Overdose

An overdose of cefuroxime can cause serious side effects, including convulsions, dizziness, loss of consciousness, and even coma in some cases. It is important to seek medical attention immediately if you think you or someone else has taken an overdose of cefuroxime.

Contraindication

Cefgrace is not to be used in patients with a known allergy or hypersensitivity to cefuroxime or other cephalosporins, or penicillins. Cefgrace should also not be used in patients with a history of liver or kidney disease.

Use Direction

Cefgrace should be taken as directed by your doctor. The dosage and frequency should not be exceeded or decreased without consulting your doctor. Taking cefuroxime with food or antacids can help reduce side effects.

Storage Condition

Cefgrace should be stored at room temperature, below 30°C (86°F). Keep it in a tightly closed container away from light, heat, and moisture.

Volume of Distribution

The volume of distribution of cefuroxime is about 0.4-0.5 L/Kg.

Half Life

Cefgrace has a half-life of 2-3 hours.

Clearance

Cefgrace is cleared from the body by both hepatic and renal pathways. The total clearance is 6.3 mL/min/kg.

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Some Frequently Asked Questions About Cefgrace

What is Cefgrace?

Cefgrace is an antibiotic used to treat a wide variety of infections caused by bacteria. It works by stopping the growth of bacteria. It is available in brand and generic form.

What is Cefgrace used to treat?

Cefgrace is indicated to treat bacterial infections, including upper and lower respiratory tract, urinary tract, skin, and soft tissue infections.

Does Cefgrace have side effects?

Cefgrace may cause side effects such as nausea, vomiting, diarrhea, headache, or dizziness.

Can Cefgrace be used to treat bronchitis?

Yes, Cefgrace is commonly used to treat infections caused by bronchitis.

Is Cefgrace a penicillin drug?

No, Cefgrace is not a penicillin drug. It is a cephalosporin antibiotic.

Is Cefgrace safe to use during pregnancy?

Cefgrace is generally considered safe to use during pregnancy. However, it is recommended to consult a doctor before using any medication during pregnancy.

What is the recommended dosage of Cefgrace?

The recommended dosage of Cefgrace depends on the severity of the infection. It is recommended to consult a doctor for the exact dosage.

Can Cefgrace be used in children?

Yes, Cefgrace can be used in children. However, the dosage may need to be adjusted according to the severity of the infection.

Can Cefgrace be taken with food?

Yes, Cefgrace can be taken with food. However, it is recommended to take the medication with a full glass of water.

Does Cefgrace cause weight gain?

No, Cefgrace does not cause weight gain. However, it is recommended to consult a doctor if any unusual symptom is observed.

Is Cefgrace an over the counter drug?

No, Cefgrace is not available as an over the counter drug. It is available with a doctor's prescription.

What is the shelf life of Cefgrace?

The shelf life of Cefgrace is two years when stored under proper conditions.

Can Cefgrace cause a yeast infection?

Yes, Cefgrace may cause a yeast infection as a side effect.

What are the common side effects of Cefgrace?

The common side effects of Cefgrace include nausea, vomiting, dizziness, headache, or diarrhea.

Can Cefgrace be used to treat a sinus infection?

Yes, Cefgrace is commonly used to treat a sinus infection.

What are the contraindications of Cefgrace?

Cefgrace should not be used in patients with hypersensitivity to cephalosporin, penicillin, or any other medication.

Can Cefgrace be taken long term?

Yes, Cefgrace can be taken long term under the supervision of a doctor.

Can Cefgrace be used to treat a urinary tract infection?

Yes, Cefgrace is commonly used to treat a urinary tract infection.

Does Cefgrace cause headache?

Yes, Cefgrace may cause a headache as a side effect.

Can Cefgrace be used to treat an ear infection?

Yes, Cefgrace is commonly used to treat an ear infection.

What should be avoided while taking Cefgrace?

Alcohol and grapefruit should be avoided while taking Cefgrace.

What is the generic name of Cefgrace?

The generic name of Cefgrace is cefuroxime axetil.

Can Cefgrace be used to treat pneumonia?

Yes, Cefgrace can be used to treat pneumonia.

What are the pharmacological actions of Cefgrace?

Cefgrace has antibacterial, anti-inflammatory, and immunomodulatory actions.

What is the dose of Cefgrace for adults?

The dose of Cefgrace for adults is 250mg-500mg twice daily.

Can Cefgrace be used to treat an STD?

Yes, Cefgrace can be used to treat some Sexually Transmitted Diseases.

Does Cefgrace interact with other medications?

Yes, Cefgrace may interact with other medications such as aspirin and ibuprofen.

Can Cefgrace cause diarrhea?

Yes, Cefgrace may cause diarrhea as a side effect.

How long does it take for Cefgrace to work?

It can take up to several days for Cefgrace to start working. However, the exact time depends on the severity of the infection.

Does Cefgrace cause drowsiness?

Yes, Cefgrace may cause drowsiness as a side effect.

How is Cefgrace administered?

Cefgrace is administered orally in tablet or capsule form.

Can Cefgrace be used to treat a strep throat?

Yes, Cefgrace is commonly used to treat a strep throat.

Does Cefgrace cause stomach upset?

Yes, Cefgrace may cause stomach upset as a side effect.

Does Cefgrace treat UTI?

Yes, Cefgrace is commonly used to treat UTI (Urinary Tract Infection).

What is the dosage of Cefgrace for children?

The dosage of Cefgrace for children depends on the age and weight of the child. It is recommended to consult a doctor for the exact dosage.

Is Cefgrace an antibiotic?

Yes, Cefgrace is an antibiotic used to treat a wide variety of bacterial infections.

Is Cefgrace effective against staphylococcus aureus?

Yes, Cefgrace is effective against staphylococcus aureus.

What is the usual duration of treatment for Cefgrace?

The usual duration of treatment with Cefgrace is 5-7 days.

Does Cefgrace have an expiration date?

Yes, Cefgrace has an expiration date. It is recommended to check the expiration date before using the medication.

Can Cefgrace be used to treat a sinus infection?

Yes, Cefgrace is commonly used to treat a sinus infection.

Is Cefgrace an over the counter drug?

No, Cefgrace is not available as an over the counter drug. It is available with a doctor's prescription.