Carbizol

Carbizol Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Carbizol is a brand name. Its generic name is Carbimazole.

Introduction

Carbizol is a medication used in the management of hyperthyroidism. It belongs to the class of drugs known as antithyroid agents. It is a pro-drug, which is converted in the body to active form called thiocyanate. It works by slowing production of thyroid hormones from the thyroid gland. Carbizol is available in the form of tablets, injections and mucosal tablets

Uses of Carbizol

Carbizol is used to treat an overactive thyroid gland (hyperthyroidism). It helps to reduce the amount of thyroid hormones released into the body. It is used to treat goiter (enlarged thyroid gland) and helps to reduce inflammation of the thyroid gland caused by certain medications or radiation therapy. Carbizol can also be used to prevent fits resulting from an overdose of thyroid hormones or radioactive iodine.

Mechanism of Action

Carbizol works by blocking an enzyme called "Thyroid peroxidase". This enzyme is responsible for the production of thyroid hormones in the body. By inhibiting the activity of this enzyme, Carbizol helps reduce the production and release of excess thyroid hormones.

How Long Does it Take to Work?

It usually takes a few weeks to feel the effects of Carbizol. However, full benefits may not be felt for up to 6 months of continued use.

Absorption

Carbizol is rapidly and almost completely absorbed following oral administration. Maximum plasma concentrations are usually observed within one hour.

Route of Elimination

The active form (thiocyanate) is eliminated mainly by excretion in the urine. The elimination half-life of the active form is approximately 8 hours.

Dosage

The typical adult dosage of Carbizol for hyperthyroidism is 15–40mg/day in single or divided doses, with gradual reduction if necessary; higher doses may be required if the patient has marked thyrotoxicosis. The usual dose for long-term maintenance therapy is 15–30mg/day. In children aged 6–12 years, the usual daily dose is 5–10mg. In younger children (aged 1–5 years) the usual dose is 2.5–5mg/day.

Administration

Carbizol may be taken with or without food. It should be taken exactly as prescribed by your physician. It is important to continue taking the medication as prescribed even if you start feeling better.

Side Effect

Common side effects of Carbizol include nausea, headache, fatigue and rash. Generally, these side effects are mild and do not affect most people. More serious side effects like anemia, liver problems, and bone marrow suppression have also been reported. If you experience any of the more serious side effects, it is important to consult your doctor immediately.

Toxicity

Chronic or prolonged exposure to Carbizol may cause liver toxicity. This may manifest as hepatitis, jaundice, and liver failure. Patients using Carbizol should be regularly monitored for signs of liver problems.

Precaution

Carbizol should not be used by patients who are hypersensitive to the drug or by patients who are pregnant or breastfeeding. It is important to inform your doctor of any other medications that you are taking, to avoid potential interactions.

Interaction

Carbizol may interact with certain medications such as diuretics, beta-blockers, allopurinol, barbiturates, calcium supplements, cyclosporine, anticoagulants, and lithium. It is important to inform your doctor of any other medications that you may be taking.

Disease Interactions

Carbizol may interact with certain medical conditions, such as pregnancy, breastfeeding, liver disease, kidney disease, and heart problems. It is important to inform your doctor of any medical conditions you may have before taking Carbizol.

Drug Interactions

Carbizol may interact with certain other medications, such as birth control pills, anticoagulants, barbiturates, and erythromycin. It is important to inform your doctor of any other medications that you may be taking.

Food Interactions

Carbizol should not be taken with high-fat meals, as this will reduce the absorption of the medication.

Pregnancy Use

Carbizol is not recommended for use during pregnancy, as it may cause harm to the developing baby.

Lactation Use

Carbizol is not recommended for use in breastfeeding women, as it may pass into breast milk and cause harm to the infant.

Acute Overdose

If more than the recommended dose of Carbizol is taken by accident, contact a doctor or poison control center immediately. Symptoms of an overdose can include headache, nausea, vomiting, confusion, seizures, and coma.

Contraindication

Carbizol is contraindicated in patients who are allergic to the drug or to related medications. Carbizol is also contraindicated in patients with severe liver disease (cirrhosis) or heart problems (cardiomyopathy).

User Direction

Carbizol should be taken exactly as prescribed by your doctor. Do not increase or decrease the dosage without consulting with your doctor first. It is important to take Carbizol regularly to get the most benefit from it.

Storage Condition

Carbizol should be stored at room temperature, away from moisture and heat.

Volume of Distribution

The volume of distribution of Carbizol is approximately 7 L/kg.

Half Life

The half-life of carbimazole is approximately 8 hours.

Clearance

The clearance of Carbizol is approximately 3.3 L/h/kg.

Here you find in details version of Carbizol

Some Frequently Asked Questions About Carbizol

What is Carbizol?

Carbizol is a medicine used to treat an overactive thyroid gland. It is also known as a thiamazole medicine. It works by decreasing the production of thyroid hormones from the thyroid gland.

What are the uses of Carbizol?

Carbizol is used to treat an overactive thyroid gland (hyperthyroidism). It helps to reduce the production of thyroid hormones by blocking the action of an enzyme in the thyroid gland that is involved in the production of these hormones.

How does Carbizol work?

Carbizol works by blocking the action of an enzyme in the thyroid gland which is involved in the production of thyroid hormones. This helps to reduce the production of these hormones, which helps to lower the level of thyroid hormones in the bloodstream.

How long does Carbizol take to work?

It usually takes several weeks for Carbizol to take effect. The full effects of the medication may take several months to become visible. Your doctor may adjust your dose until the desired effect is achieved.

How do I take Carbizol?

Carbizol should be taken as directed by your doctor. Follow all directions on your prescription label and read all medication guides. Do not take more or less of this medication than prescribed. Swallow the tablet whole with a full glass of water. You may take the tablets with or without food.

What are the side effects of Carbizol?

Common side effects of Carbizol include headache, nausea, vomiting, loss of appetite, fatigue, and dizziness. More serious side effects include rash, fever, sore throat, and chest pain. If you experience any of these symptoms, call your doctor right away.

What are the precautions for taking Carbizol?

Before taking Carbizol, tell your doctor if you have liver disease, kidney disease, anemia, or any other medical conditions. Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Also, avoid using antacids or laxatives within two hours of taking this medication.

Is Carbizol safe to take during pregnancy?

Carbizol should only be used during pregnancy if the potential benefits outweigh the risks. Talk to your doctor about the risks and benefits of taking this medication during pregnancy before starting treatment.

Can I take Carbizol while breastfeeding?

Carbizol may pass into breast milk and could potentially harm a nursing baby. Talk to your doctor about the risks and benefits of taking this medication while breastfeeding before starting treatment.

Is Carbizol habit-forming?

No, this medication is not habit-forming. However, it is important to take Carbizol exactly as prescribed by your doctor. Do not stop taking it or change the dose without first talking to your doctor.

What if I miss a dose of Carbizol?

If you miss a dose of Carbizol, take it as soon as you remember, unless it is close to the time for your next dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

What should I avoid while taking Carbizol?

Do not take antacids or laxatives within two hours of taking Carbizol. Avoid drinking grapefruit juice while taking this medication, as it could increase the effects of Carbizol. Talk to your doctor about any other drugs, supplements, or foods that you should avoid while taking this medicine.

Is there an alternative to Carbizol?

There are other medications that can be used to treat an overactive thyroid gland. Your doctor may decide to switch you to another medicine that may be more effective in managing your symptoms. Talk to your doctor about the risks and benefits of other medications.

Can I take other medications with Carbizol?

You should always tell your doctor about all other medications you are taking, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medications may interact with Carbizol, so it is important to tell your doctor about all the medications you are taking.

Is Carbizol available in generic form?

Yes, Carbizol is available in generic form. The generic form of Carbizol is usually less expensive than the brand name version, although not all generic versions may be available.

Is Carbizol safe for children?

Carbizol is not recommended for use in children under the age of 12. Talk to your doctor about other medications that may be suitable for children.

What else should I be aware of when taking Carbizol?

It is important to keep all appointments with your doctor while taking Carbizol. Your doctor may perform regular blood tests to monitor for side effects or check your response to the medication. Also, avoid drinking alcohol while taking this medication as it can increase the risk of liver damage.

When should I contact my doctor if I am taking Carbizol?

Contact your doctor if you experience any unusual symptoms while taking Carbizol. Also, contact your doctor if your symptoms do not improve or if they worsen while taking this medication.

What happens if I overdose on Carbizol?

If you or someone else has taken an overdose of Carbizol, seek medical attention immediately. Overdosing on Carbizol can be serious and potentially life-threatening.

Is Carbizol covered by insurance?

The cost of Carbizol will vary depending on your insurance coverage. Call your insurance company to find out more about your coverage and any out-of-pocket costs.

How is Carbizol stored?

Carbizol should be stored at room temperature, away from moisture and heat. Keep it in a secure container and out of the reach of children.

Are there any other brand names for Carbizol?

Carbizol is also known as Neo-Mercazole, Neo-Merz, and Neacarbazole. These are all brand names for Carbizol.

What are the potential long-term effects of taking Carbizol?

Long-term use of Carbizol may increase the risk of some side effects, including liver damage, bone marrow suppression, and decreases in white blood cells. Talk to your doctor about the risks and benefits of long-term use of this medication.

Can Carbizol be stopped suddenly?

No, do not stop taking Carbizol suddenly as this could be dangerous. Your dose should be gradually decreased over time and stopped as directed by your doctor. Do not stop taking this medication without first discussing it with your doctor.

What is the best way to take Carbizol?

The best way to take Carbizol is as directed by your doctor. Take the medication with or without food, and swallow the tablet whole with a full glass of water. Do not take more or less of this medication than prescribed by your doctor.

Can I take Carbizol if I am also taking other medications?

Before taking Carbizol, tell your doctor about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medications may interact with Carbizol, so it is important to tell your doctor about all the medications you are taking.

Can I take Carbizol if I have kidney disease?

Before taking Carbizol, tell your doctor if you have kidney disease. Your doctor may need to adjust your dose or recommend an alternative medication.

Can I take Carbizol if I have anemia?

Before taking Carbizol, tell your doctor if you have anemia. Your doctor may need to adjust your dose or recommend an alternative medication.

Can Carbizol cause weight gain?

Weight gain is a potential side effect of Carbizol. Talk to your doctor if you are experiencing unexplained weight gain while taking this medication.

Is Carbizol a steroid?

No, Carbizol is not a steroid. It is an antithyroid medicine used to treat an overactive thyroid gland.

What other antithyroid medications are available?

Other antithyroid medications are available, including methimazole, propylthiouracil, and potassium iodide. Your doctor will determine which medication is most appropriate for your condition.

What are the signs and symptoms of an overactive thyroid?

Symptoms of an overactive thyroid include fatigue, weight loss, rapid heartbeat, irritability, increased perspiration, tremors, and difficulty sleeping. If you are experiencing any of these symptoms, talk to your doctor.

What is the difference between Carbizol and methimazole?

Carbizol and methimazole are both antithyroid medications used to treat an overactive thyroid gland. The main difference between these medications is that Carbizol is a longer acting form, and methimazole is a shorter acting form.

Can Carbizol cause hair loss?

Hair loss is a potential side effect of Carbizol. Talk to your doctor if you are experiencing unexplained hair loss while taking this medication.

Is there a generic version of Carbizol?

Yes, Carbizol is available in generic form. The generic form of Carbizol is usually less expensive than the brand name version, although not all generic versions may be available.

Should I take Carbizol if I am pregnant?

Carbizol should only be used during pregnancy if the potential benefits outweigh the risks. Talk to your doctor about the risks and benefits of taking this medication during pregnancy before starting treatment.

What should I do if I experience side effects from taking Carbizol?

If you experience any side effects while taking Carbizol, talk to your doctor. They may be able to reduce your dose or switch you to another medication that may be more effective and have fewer side effects.

How long does it take for Carbizol to start working?

It may take several weeks for Carbizol to start working. The full effects of the medication may take several months to become visible. Your doctor may adjust your dose until the desired effect is achieved.

If I am taking Carbizol, do I need to have regular blood tests?

Yes, it is important to have regular blood tests while taking Carbizol. These tests will help your doctor monitor your progress and check for any side effects. Talk to your doctor about how often you need to have these tests.

Can Carbizol cause dizziness?

Yes, dizziness is a potential side effect of Carbizol. If you experience any dizziness while taking this medication, talk to your doctor.

Can Carbizol cause dry mouth?

Yes, dry mouth is a potential side effect of Carbizol. If you experience any dry mouth while taking this medication, talk to your doctor.

Is Carbizol safe to take if I have liver disease?

Before taking Carbizol, tell your doctor if you have liver disease. Your doctor may need to adjust your dose or recommend an alternative medication.