Cabre

Cabre Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Cabre is a brand name. Its generic name is Cabergoline.

Introduction

Cabre is a dopamine agonist that is used to treat conditions such as, hyperprolactinemia, Parkinson’s Disease, and reproductive disorders. It is readily available in both oral and intravenous forms.

Uses For

Cabre is used to treat hyperprolactinemia, a condition in which the body produces too much of the hormone prolactin. It is also used to treat Parkinson's disease, infertility, and uses off-label for other conditions.

Mechanism of Action

Cabre works by activating dopamine receptors, which helps to reduce the amount of prolactin released by the pituitary gland.

How Long Does it Take to Work

Cabre typically starts working soon after taking it. However, it may take up to two weeks for therapeutic levels of the medication to be reached in the body.

Absorption

Cabre is rapidly and well absorbed from the gastrointestinal tract and is widely distributed throughout the body.

Route of Elimination

Cabre is mainly eliminated through the kidneys; approximately 80% of the drug is excreted in the urine.

Dosage

The exact dosage of Cabre depends on the severity of the condition being treated and the individual's response to the drug. For hyperprolactinemia, the initial dose is typically 0.5 to 1 mg twice weekly, and the maximum is 4 mg per week.

Administration

Cabre is available as a pill and is to be taken orally. The tablets can be taken with or without food.

Side Effect

The most common side effects of Cabre include nausea, vomiting, diarrhea, constipation, dizziness, headache, tiredness, and difficulty sleeping.

Toxicity

Cabre is generally well-tolerated when taken as prescribed, however it can cause serious toxicity if taken in large amounts.

Precaution

This medication should not be taken by anyone who is allergic to cabergoline or any of its ingredients. Women who are pregnant or breastfeeding should consult a physician to discuss the risks.

Interaction

Cabre can interact with certain medications, herbs, or supplements. Patients should inform their healthcare provider about all medications they are taking before beginning therapy.

Disease Interaction

Cabre should not be used by patients with uncontrolled hypertension, severe heart or liver disease, and uncontrolled psychotic disorders.

Drug Interaction

Cabre can interact with certain medications, such as certain antidepressants, antipsychotics, and anti-seizure medications.

Food Interactions

Grapefruit and grapefruit juice should not be used while taking Cabre as they can increase the risk of side effects.

Pregnancy Use

Cabre should only be used by pregnant women only when absolutely necessary, as the risks outweigh the benefits.

Lactation Use

Cabre should not be used by breastfeeding women as it can pass into breast milk and may cause harm to the infant.

Acute Overdose

In the event of an acute overdose, seek medical attention immediately. Symptoms can include severe nausea, vomiting, diarrhea, and dizziness.

Contraindication

Cabre should not be used in patients who are hypersensitive to the drug or any of its inactive ingredients.

Use Direction

Cabre is generally taken orally with or without food two times each week, according to the instructions of a healthcare provider.

Storage Condition

Store Cabre at room temperature, away from direct sunlight and heat.

Volume of Distribution

Cabre has an apparent volume of distribution of approximately 0.35 L/kg.

Half Life

The half-life of cabergoline is approximately 63 - 68 hours.

Clearance

Cabre is cleared from the body primarily via the kidneys; approximately 80% is excreted as metabolites.

Dosage Information

  • For Hyperprolactinemia: The starting dose is typically 0.5 to 1 mg orally twice a week, and the maximum is 4 mg orally per week.
  • For Parkinson's Disease: The starting dose is 0.25 to 0.50 mg, taken orally in two divided doses. This dose can be increased by 0.25 to 0.50 mg every four weeks until symptoms are relieved.
  • For Infertility: 0.75 mg twice a week up to 6 months.

Here you find in details version of Cabre

Some Frequently Asked Questions About Cabre

What is Cabre?

Cabre is a dopamine agonist medication used to treat an array of medical conditions. The most common use for cabergoline is to treat hyperprolactinemia, a condition characterized by abnormally high levels of prolactin (a hormone responsible for breast milk production). Other uses include the treatment of Parkinson's disease, fertility issues, and certain pituitary tumors.

Whatare the side effects of Cabre?

Common side effects of cabergoline include nausea, constipation, headache, dizziness, and fatigue. Other potential, but less common, side effects include abdominal pain, chest pain, diarrhea, irregular heartbeats, and pains in the leg and arms.

What are the possible interactions of Cabre?

Cabre may interact with medications such as erythromycin, fluoxetine, and ketoconazole. It may also interact with other dopamine agonists, such as bromocriptine, or with other drugs that can affect dopamine, such as antipsychotics and opioids. Before taking cabergoline, it is important to discuss potential interactions with a doctor or healthcare provider.

What is the usual dose of Cabre?

The usual starting dose of cabergoline is 0.25mg twice per week, as a single dose or the two doses may be split into a single 0.25mg dose per day. Depending on how an individual person responds to the medication, the dose may be increased by 0.5mg to 1mg per week. The daily dose should not exceed 1mg.

Who can take Cabre?

Cabre is not recommended for use in children. In order for an individual to take cabergoline, a doctor or healthcare provider must assess their health and determine whether or not cabergoline is a suitable medication. People with certain congestive heart diseases, including heart valve dysfunction, may be advised to not take cabergoline.

How long should Cabre be taken for?

Cabre should be taken as long as the doctor recommends. Depending on the medical condition being treated, cabergoline may need to be used for a few weeks or months, or it may need to be taken long-term. It is important to not discontinue cabergoline use suddenly, as this can result in unwanted withdrawal effects.

When will I see results after taking Cabre?

The time it takes to see results after taking cabergoline will vary depending on the medical condition being treated and the individual's response to the medication. In general, it may take a few weeks to see the desired effects.

What should I do if I forget to take a dose of Cabre?

If a dose of cabergoline is forgotten, it should be taken as soon as remembered. If it is almost time for the next dose, it should be skipped and the regular dosing schedule should be resumed. Double doses should never be taken and a doctor or healthcare provider should be consulted if multiple doses of cabergoline are forgotten.

Should I avoid certain activities and foods while taking Cabre?

It is important to avoid activities that require sharp focus and alertness while taking cabergoline, as it can cause dizziness and make it difficult to concentrate. As well, alcohol should be avoided, as it can worsen the dizziness and other side effects associated with cabergoline. As for foods, it is important to avoid foods that can interact with cabergoline, such as those high in tyramine, such as aged cheeses, sour cream, yogurt, pickled products, and dried or cured meats.

What are the possible withdrawal symptoms of Cabre?

Some of the withdrawal symptoms associated with the sudden discontinuation of cabergoline include nausea, vomiting, fatigue, abnormal dreams, depression, headache, and dizziness. If cabergoline is suddenly stopped, a doctor or healthcare provider should be consulted to help manage the withdrawal symptoms.

Does Cabre help with weight loss?

Cabre may help to decrease body weight and fat due to its ability to lower prolactin levels. However, it should not be used as a weight loss medication and should only be taken as prescribed by a doctor or healthcare provider.

What should I do if I experience a severe allergic reaction while taking Cabre?

If an individual experiences a severe allergic reaction while taking cabergoline, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat, they should seek immediate medical attention. The individual should stop taking cabergoline and notify their doctor or healthcare provider.

Does Cabre interact with other drugs?

Cabre may interact with other drugs, including certain medications such as erythromycin, fluoxetine, and ketoconazole. It may also interact with other dopamine agonists, such as bromocriptine, or with other drugs that can affect dopamine, such as antipsychotics and opioids. It is important to talk to a doctor or healthcare provider about potential interactions before taking cabergoline.

Can I overdose on Cabre?

It is possible to overdose on cabergoline. Signs of an overdose may include severe nausea, vomiting, chest pain, headache, confusion, and seizures. If an overdose is suspected, medical attention should be sought immediately.

Should I take Cabre with food?

It is not necessary to take cabergoline with food. However, it may make it easier on the stomach if taken with food or after a snack. Ask a doctor or healthcare provider for advice on whether to take cabergoline with food.

Is Cabre a controlled substance?

No, cabergoline is not a controlled substance in most countries.

Does Cabre reduce anxiety?

Cabre is not an antidepressant and is not typically used to reduce anxiety. However, it has been used to treat symptoms associated with anxiety, such as edginess and irritability.

Will Cabre cause me to gain weight?

Cabre may cause weight gain as a side effect, especially if it is taken for a long period of time. Talk to a doctor or healthcare provider about other side effects that could occur with cabergoline and about potential weight gain prevention strategies.

Does Cabre interact with antacids or aspirin?

Cabre is not typically known to interact with antacids or aspirin. However, it can interact with other medications, including erythromycin, fluoxetine, and ketoconazole. It is important to talk to a doctor or healthcare provider before taking cabergoline with any other medications.

Can I take Cabre if I am pregnant?

Cabre should not be taken during pregnancy, as it may affect the development of the baby. If an individual is pregnant, it is important to talk to a doctor or healthcare provider about their medical condition and possible medication options.

Can Cabre be taken by people with diabetes?

Cabre may be appropriate for people with diabetes, as long as their doctor or healthcare provider has approved its use. It is important to monitor blood sugar levels and inform a doctor or healthcare provider of any changes that occur while taking cabergoline.

Can Cabre cause depression and other mental health issues?

Cabre can cause depression and other mental health issues as a side effect. If an individual experiences any mental health changes while taking cabergoline, they should talk to their doctor or healthcare provider as soon as possible.

Can I take Ibuprofen while taking Cabre?

Ibuprofen can typically be taken while taking cabergoline. However, it is important to talk to a doctor or healthcare provider before taking any additional medications, as cabergoline may interact with other medications.

Can Cabre cause insomnia?

Cabre can cause insomnia as a side effect. If insomnia is experienced, talk to a doctor or healthcare provider who may be able to adjust the cabergoline dose or prescribe other medication to help manage the insomnia.

Can I take Cabre while breastfeeding?

Cabre is not recommended for use in people who are breastfeeding. If a doctor or healthcare provider prescribes cabergoline, it is important to discuss the risks and alternatives of taking the medication while breastfeeding.

What are the long-term effects of Cabre?

The long-term effects of cabergoline depend on the medical condition being treated and the individual's response to the medication. It is important to discuss potential long-term effects with a doctor or healthcare provider.

Can I take Cabre if I have high blood pressure?

Cabre may be suitable for people with high blood pressure, as long as it is being monitored and the doctor or healthcare provider has approved its use. It is important to inform a doctor or healthcare provider of any changes that occur in blood pressure while taking cabergoline.

Can Cabre cause headaches?

Headaches are a common side effect of cabergoline. If an individual experiences frequent or severe headaches while taking cabergoline, they should talk to a doctor or healthcare provider about other possible medication options.

Is Cabre a safe medication?

Cabre is generally considered a safe medication when taken as prescribed by a doctor or healthcare provider. However, it can cause side effects and it is important to discuss possible risks and benefits with a doctor or healthcare provider before taking cabergoline.

What is the half-life of Cabre?

The half-life of cabergoline is approximately 63 hours, so it can remain in the body for 2 to 4 days after it is taken.

Is Cabre an opioid or a steroid?

Cabre is neither an opioid nor a steroid. It is a dopamine agonist and is used to treat a variety of medical conditions.

Can Cabre cause high cholesterol?

It is possible for cabergoline to increase cholesterol levels. It is important to monitor cholesterol levels and inform a doctor or healthcare provider of any changes that occur while taking cabergoline.

Does Cabre cause hair loss?

Hair loss is a known side effect of cabergoline. If an individual experiences sudden or excessive hair loss while taking cabergoline, they should talk to a doctor or healthcare provider about other medication options.

Can Cabre be taken with thyroid medications?

Cabre can be taken with thyroid medications, as long as a doctor or healthcare provider has approved its use. It is important to talk to a doctor or healthcare provider before taking any additional medications, as some medications may interact with cabergoline.

Can Cabre make me feel more energetic?

Cabre can make an individual feel more energized, as it can reduce fatigue and improve concentration. However, it is important to talk to a doctor or healthcare provider about its use in order to determine whether it is the best medication for an individual.

Can Cabre cause a rash or skin irritation?

Skin rash and irritation is a known side effect of cabergoline. If an individual experiences a rash or skin irritation, they should contact their doctor or healthcare provider.

Can I drink coffee while taking Cabre?

Coffee or other caffeinated beverages can typically be consumed while taking cabergoline. However, it is important to talk to a doctor or healthcare provider before consuming any additional beverages, and it is important to monitor for any changes associated with the consumption of caffeine.