Bowelac

Bowelac Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Bowelac is a brand name. Its generic name is Lactulose.

Bowelac

Bowelac is a synthetic combination of two naturally-occurring sugars, glucose and galactose. It is used as a laxative to treat constipation and to reduce hepatic encephalopathy. The mechanism of action of lactulose is not fully understood, but it appears to either displace toxins or increase stool water content or both. Bowelac can take up to 72 hours to take effect.

Absorption and Route of Elimination

Absorption of lactulose is incomplete, so most of it passes through the intestine without being absorbed. It is fermented by bacteria in the digestive tract absorbs some of it. The remainder, usually discharged in the stools, is metabolized by bacteria in the large intestine to lactic and acetic acids. These metabolites are rapidly absorbed and metabolized by the body.

Dosage and Administration

The recommended dosage of lactulose is 15-45ml per day (15mL for children under 2 years of age). It should be taken in three or four divided doses with 1-2 hours between doses, and on an empty stomach. Bowelac can be taken with water, fruit juice, or milk.

Side Effects, Toxicity, and Precaution

The most common side effects of lactulose are stomach cramping, bloating, and diarrhea. It can also cause electrolyte disturbances, vitamin deficiencies, and dehydration. Bowelac should be used with caution in patients with hepatic encephalopathy, as it may increase the level of ammonia in the blood. It should not be used in patients with severe electrolyte disturbance, malabsorption, or certain severe gastrointestinal diseases. It should also be used with caution in pregnant and lactating women.

Interaction

Bowelac may interact with some medications, including laxatives, antibiotics, antacids, and other drugs that decrease peristalsis. It should also not be taken with oral vitamins and minerals, as it may decrease their absorption.

Disease Interactions

Bowelac may worsen symptoms of some diseases, including renal impairment, intestinal obstruction, colitis, and Crohn's disease. It should also not be used in patients with diabetic ketoacidosis.

Drug Interactions

Bowelac may reduce the absorption of some medications, including antibiotics, oral vitamin and mineral supplements, and antacids. It may also interfere with the effect of certain drugs, such as lithium and some cancer medications.

Food Interactions

Bowelac may interact with some foods, including dairy products, and foods containing sorbitol. It is recommended to avoid these foods when taking lactulose.

Pregnancy and Lactation Use

Bowelac is generally considered safe for pregnant and lactating women. However, it is recommended to consult with a healthcare professional before taking this medication during pregnancy or lactation.

Acute Overdose

An acute overdose of lactulose may lead to watery stools, electrolyte imbalance, abdominal pain, and nausea or vomiting. It is recommended to seek medical help if a person experiences any of these symptoms.

Contraindication

Bowelac is contraindicated in patients with known hypersensitivity to it or any other components of its formulation, as well as in patients with severe electrolyte disturbances, malabsorption, and certain gastrointestinal diseases.

Use Direction

Bowelac should be taken as directed by a healthcare professional. Generally, it is recommended to take 15-45ml (15mL for children under 2 years of age) with 1-2 hours between doses, on an empty stomach.

Storage Conditions

The drug should be stored in tightly closed containers in room temperature away from heat and moisture.

Volume of Distribution

Bowelac is not highly lipophilic and thus not expected to distribute into the central nervous system. The volume of distribution is up to 10-20 L/kg.

Half Life

The elimination half-life is approximately 6.2 hours.

Clearance

The clearance of lactulose is about 0.1 L/hr/kg.

Here you find in details version of Bowelac

Some Frequently Asked Questions About Bowelac

What is Bowelac?

Bowelac is a non-digestible disaccharide sugar used as a medication and probiotic. Bowelac is prescribed to treat constipation and hepatic encephalopathy. It is also used to prevent fecal impaction.

How does Bowelac work?

Bowelac works by decreasing the amount of ammonia in the gut and increasing the amount of fecal water in the bowels to make the stools softer and easier to pass. It also increases the amount of beneficial bacteria in the gut, which helps to reduce the amount of ammonia produced.

What are the possible side effects of taking Bowelac?

The possible side effects of taking Bowelac include bloating, gas, stomach cramps, and diarrhea. Rarely, more serious side effects such as low blood potassium levels, rapid heartbeat, and changes in blood glucose levels may occur. Be sure to talk to your doctor if any of these side effects occur.

What is the recommended dosage for adults taking Bowelac?

The recommended dose for adults taking Bowelac is 15-45 ml once or twice per day. Dosage needs to be adjusted according to response and effects.

How should I take Bowelac?

Bowelac should be taken with a full glass of water. It can also be mixed with other liquids such as juice or coffee. Bowelac should be taken on an empty stomach or at least 1 hour before or 2 hours after a meal.

Can I take Bowelac with other medications?

You should always consult your doctor before taking Bowelac with other medications. Bowelac may interact with other medications so it is best to discuss any potential interactions with your doctor before taking it.

What if I forget to take my dose of Bowelac?

If you forget to take your dose of Bowelac, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your regular dose at the usual time.

Is Bowelac safe to take during pregnancy?

Bowelac is considered safe to take during pregnancy, but should only be taken under a doctor’s supervision. Be sure to discuss any potential risks or interactions with your doctor.

Can children take Bowelac?

Bowelac is not recommended for children under the age of 2 years. Children over the age of 2 years may take Bowelac but should do so only under the supervision of a doctor.

What are the common minor side effects of taking Bowelac?

The common minor side effects of taking Bowelac include stomach cramps, bloating, gas, and diarrhea. If any of these side effects become severe or do not go away, contact your doctor.

Can I drink alcohol while taking Bowelac?

Alcohol may interfere with the effectiveness of Bowelac. If you are taking Bowelac, it is best to avoid or limit alcohol consumption.

What should I do if I experience severe side effects while taking Bowelac?

If you experience severe side effects such as nausea, vomiting, dizziness, lightheadedness, rapid heartbeat, changes in blood glucose levels and/or low blood potassium levels, stop taking Bowelac and contact your doctor immediately.

Can I take Bowelac with antacids or laxatives?

It is not recommended to take Bowelac with antacids or laxatives. If you are taking either of these medications, discuss them with your doctor before taking Bowelac.

Can people with diabetes take Bowelac?

People with diabetes may take Bowelac, however it is recommended to monitor their blood sugar levels closely as it may have an effect on levels. It is best to discuss any potential interactions with a doctor before taking Bowelac.

Is Bowelac a laxative?

Bowelac is not technically a laxative, but it is used to relieve constipation because it softens the stool and helps it pass more easily. It is therefore considered a type of softener.

Can I take other medications while taking Bowelac?

You should always consult your doctor before taking any other medications while taking Bowelac. Bowelac may interact with other medications, so it is best to discuss any potential interactions with your doctor before taking it.

Can Bowelac be used to treat diarrhea?

Bowelac may be used to treat some types of diarrhea, however it is important to speak with your doctor first to discuss the most appropriate treatment. Taking too much lactulose can also cause diarrhea.

What are the long-term effects of taking Bowelac?

The long-term effects of taking Bowelac depend on the dosage and individual. The most common long-term effects are bloating, gas, and loose stools. Long-term use of Bowelac may also lead to gastritis, electrolyte disturbances, and cholelithiasis (gallstones). Speak to your doctor if you have any concerns.

Can Bowelac be used to treat constipation?

Yes, Bowelac is often used to treat constipation by softening the stool and encouraging movement of the bowels. It is usually taken as a single dose at the same time each day.

What is the best time to take Bowelac?

The best time to take Bowelac is with a full glass of water either on an empty stomach or at least 1 hour before or 2 hours after a meal.

Should I take Bowelac in the morning or evening?

The best time to take lactulose will depend on the individual. Some people may find that it works better for them if they take it in the morning, whereas others may prefer to take it in the evening.

Can Bowelac be used for weight loss?

Bowelac is not typically used for weight loss and there is no evidence to suggest that it can help with weight loss. It is best to speak to your doctor if you are considering taking a lactulose to aid weight loss.

What are the benefits of taking Bowelac?

The main benefit of taking Bowelac is that it is a non-digestible sugar used to treat constipation, hepatic encephalopathy and prevent fecal impaction. It works by decreasing the amount of ammonia in the gut and increasing the amount of fecal water in the bowels to make the stools softer and easier to pass. It also increases the amount of beneficial bacteria in the gut, which helps to reduce the amount of ammonia produced.

Can Bowelac be used to reduce ammonia levels in the body?

Yes, Bowelac is often used to reduce ammonia levels in the body by decreasing the amount of ammonia in the gut and increasing the amount of fecal water in the bowels to make the stools softer and easier to pass. It also increases the amount of beneficial bacteria in the gut, which helps to reduce the amount of ammonia produced.

Is there a generic form of Bowelac available?

Yes, some generic forms of Bowelac are available. It is best to speak to your doctor or pharmacist to determine which form is best for you.

Does Bowelac have any potential interactions with other medications?

Yes, Bowelac may have potential interactions with other medications. It is important to talk to your doctor or pharmacist before taking any other medications while taking lactulose.

Will Bowelac cause bloating or gas?

Yes, bloating and gas are common side effects of taking Bowelac. If these side effects become severe or do not go away, contact your doctor.

How long does it take Bowelac to work?

The amount of time it takes for Bowelac to work varies from person to person. In general, it takes around 6-8 hours for Bowelac to start having an effect.

Are there any foods I should avoid while taking Bowelac?

It is not generally recommended to avoid any specific foods while taking Bowelac but it is best to speak to your doctor or pharmacist for advice on foods that could interfere with its effectiveness.

What is the active ingredient in Bowelac?

The active ingredient in Bowelac is a disaccharide sugar called lactulose.

Can Bowelac be taken on an empty stomach?

Yes, Bowelac can be taken on an empty stomach or at least 1 hour before or 2 hours after a meal.

Is there an appropriate storage temperature for Bowelac?

Yes, Bowelac should be stored at room temperature (15-30°C). It should not be refrigerated.

Is Bowelac available over-the-counter?

Yes, Bowelac is available over-the-counter in some countries. It is best to check with your local pharmacy or doctor for advice and availability.

Can I take Bowelac before bed?

Yes, Bowelac can be taken before bed. However, it is best to take it with a full glass of water as taking it with other liquids such as juice or coffee may interfere with its effectiveness.

Should I take Bowelac with food?

It is not generally recommended to take Bowelac with food as this may interfere with its effectiveness. It is best take it on an empty stomach or at least 1 hour before or 2 hours after a meal.

Can I take Bowelac if I am allergic to milk or dairy products?

Yes, Bowelac is suitable for people who are allergic to milk or dairy products, as it does not contain these ingredients.

Does Bowelac have any interaction with other herbs and supplements?

Yes, Bowelac may interact with other herbs and supplements. It is important to talk to your doctor or pharmacist before taking any other herbs or supplements while taking Bowelac.

What if I take too much Bowelac?

If you take too much Bowelac, you may experience an increase in bloating, gas and loose stools. If you take more than your prescribed dose, seek medical attention immediately.

Should I take Bowelac if I have Crohn's disease?

It is best to speak to your doctor before taking Bowelac is you have Crohn's disease, as it may interact with other medications being taken. Your doctor may be able to recommend an alternative treatment.

What is the shelf life of Bowelac?

The shelf life of Bowelac is two years. It is important to make sure that you do not take Bowelac beyond the expiration date.