Benzathine Penicillin
Benzathine Penicillin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Benzathine Penicillin is a brand name. Its generic name is Benzylpenicillin.
Introduction
Benzathine Penicillin, also known as penicillin G, is an antibiotic used to treat bacterial infections. It belongs to a group of antibiotics called beta-lactams, and works by interfering with the production of bacterial cell walls.Uses
Benzathine Penicillin is used to treat infections caused by susceptible bacteria, including: skin infections, urinary tract infections, throat infections, and infections of the respiratory tract. It is also used to prevent post-surgical wound infections and preterm delivery.Mechanism of Action
Benzathine Penicillin works by irreversibly binding to penicillin-binding proteins (PBPs) in bacterial cell walls, preventing the bacteria from forming new cell walls during multiplication. This causes bacteria cells to rupture and die, ultimately leading to the clearing of infection.How Long Does It Take to Work?
It typically takes about 1 to 2 weeks for benzylpenicillin to begin working. However, this time can vary depending on the severity of the infection.Absorption
Benzathine Penicillin is not efficiently absorbed from the gastrointestinal tract and must be administered intravenously or intramuscularly.Route of Elimination
Benzathine Penicillin is eliminated primarily by the kidneys by glomerular filtration.Dosage
The dosage of benzylpenicillin will depend on the type and severity of the infection. Typical intravenous dosage for adults is 500,000 to 1 million units daily, administered in four to six equal doses over the course of 24 hours. Intramuscular doses should be 600,000 to 1 million units daily for adults, given in two to four equal doses.Administration
Benzathine Penicillin can be administered intravenously or intramuscularly. It should be reconstituted according to the manufacturer's instructions prior to administration. It should only be administered by a healthcare professional.Side Effect
Common side effects of benzylpenicillin include nausea, vomiting, and diarrhea. More severe side effects can include anaphylaxis, Stevens-Johnson syndrome, and interstitial nephritis.Toxicity
Benzathine Penicillin is associated with a low rate of toxicity. However, severe hypersensitivity reactions and renal toxicity have been reported in rare cases.Precautions
It is important to tell your doctor about any allergies you have and any medications you are taking. Patients with renal impairment, asthma, and suspected or confirmed sensitivity to penicillins should not be given benzylpenicillin.Interaction
Benzathine Penicillin can interact with other drugs, including antacids, diuretics, and probenecid, increasing the risk of side effects or reducing the effectiveness of the drug.Disease Interaction
Patients with a history of allergies or asthma should not be given benzylpenicillin, as the risk of a serious allergic reaction is high. Patients with renal impairment should also be cautious when taking the drug, as it may cause renal toxicity.Drug Interaction
Benzathine Penicillin can interact with other drugs, including antacids, diuretics, and probenecid, increasing the risk of side effects or reducing the effectiveness of the drug.Food Interactions
There are no known food interactions associated with benzylpenicillin.Pregnancy Use
Benzathine Penicillin should only be used during pregnancy if the potential benefit outweighs the potential risk.Lactation Use
It is not known if benzylpenicillin is excreted in breast milk. Therefore, it is best to avoid using the drug while breastfeeding.Acute Overdose
In the event of an acute overdose, benzylpenicillin should be immediately removed from circulation. Symptoms of an overdose include confusion, seizures, and abdominal pain.Contraindication
Patients with a known hypersensitivity to penicillins or cephalosporins should not be given benzylpenicillin.Use Direction
Benzathine Penicillin should be used exactly as prescribed by a healthcare provider.Storage Condition
Benzathine Penicillin should be stored at 20-25°C (68-77°F) and protected from light.Volume of Distribution
Benzathine Penicillin has a volume of distribution of 0.4-1.1 L/kg.Half Life
The half life of benzylpenicillin is approximately 30 minutes.Clearance
The clearance of benzylpenicillin is approximately 0.3-0.8 L/hr/kg.Here you find in details version of Benzathine Penicillin
Some Frequently Asked Questions About Benzathine Penicillin
Benzathine Penicillin Questions and Answers
What is Benzathine Penicillin?
Benzathine Penicillin, also known as penicillin G, is a form of antibiotic drug belonging to the penicillin family. It is used to treat a wide range of bacterial infections.
How does Benzathine Penicillin work?
Benzathine Penicillin works by stopping the growth of bacteria. It does this by preventing the bacteria from forming a protective cell wall. This stops them from growing and multiplying.
What infections does Benzathine Penicillin treat?
Benzathine Penicillin is used to treat a wide range of bacterial infections, such as chest infections, skin infections, blood infections, bone infections, respiratory tract infections, dental abscesses, and meningitis.
Can I buy Benzathine Penicillin over the counter?
No, Benzathine Penicillin is a prescription-only medication and must be prescribed by a doctor before it can be obtained.
How do I take Benzathine Penicillin?
Benzathine Penicillin is usually prescribed as an injection and is administered directly into the muscle or vein. It may also be prescribed as tablets or a liquid suspension. Your doctor will advise you on the best method of taking Benzathine Penicillin.
What are the side effects of Benzathine Penicillin?
The most common side effects of Benzathine Penicillin include nausea, vomiting, diarrhea, and rash. Other possible side effects include dizziness, headache, fever, and stomach pain.
Is Benzathine Penicillin safe to take during pregnancy?
It is generally considered safe for pregnant women to take Benzathine Penicillin, however it is important to discuss any potential risks with your doctor before taking this medication.
What should I do if I forget to take a dose of Benzathine Penicillin?
If you forget to take a dose of Benzathine Penicillin, take it as soon as you remember and then continue as normal. Do not take a double dose to make up for a forgotten dose.
Can I drink alcohol while taking Benzathine Penicillin?
It is generally not advised to drink alcohol while taking Benzathine Penicillin as it can cause further nausea and can increase the risk of side effects. It is best to avoid alcohol until you have finished taking the course.
Does Benzathine Penicillin interact with any other medications?
Yes, Benzathine Penicillin can interact with other medications, including antacids, probenecid, and certain blood thinners. It is important to tell your doctor or pharmacist about any other medications that you are taking before starting Benzathine Penicillin.
Does Benzathine Penicillin cause any long-term effects?
No, there have been no reports of long-term effects caused by Benzathine Penicillin. It is usually safe for long-term use if taken as prescribed.
How long should I take Benzathine Penicillin for?
Benzathine Penicillin is usually taken for a short period of time, usually no more than 5-7 days. It is important to finish the course of medication as prescribed in order for it to work effectively.
How long does it take for Benzathine Penicillin to work?
The effects of Benzathine Penicillin should begin to be felt after a few days of taking the medication. However, it is important to finish the course of medication to ensure that the infection does not return.
Can Benzathine Penicillin cause allergic reactions?
Yes, some people may experience an allergic reaction to Benzathine Penicillin. Signs of an allergic reaction include rash, itching, swelling, and difficulty breathing.
What should I do if I experience an allergic reaction to Benzathine Penicillin?
If you experience any of the symptoms of an allergic reaction, it is important to stop taking the medication and seek medical attention immediately.
Can I take Benzathine Penicillin if I am breastfeeding?
It is usually safe for breastfeeding women to take Benzathine Penicillin, however it is important to discuss any potential risks with your doctor before taking this medication.
Is Benzathine Penicillin suitable for children?
Yes, Benzathine Penicillin is suitable for children. However, it is important to consult with a doctor before giving Benzathine Penicillin to a child, as the dosage may need to be adjusted.
Can I take Benzathine Penicillin with other antibiotics?
No, it is not generally recommended to take Benzathine Penicillin with other antibiotics as this can increase the risk of side effects and reduce the effectiveness of the medication.
What should I do if I experience any side effects while taking Benzathine Penicillin?
If you experience any unpleasant side effects while taking Benzathine Penicillin, it is important to discuss these with your doctor as soon as possible. They can advise you on the best course of action.
What should I do if I miss a dose of Benzathine Penicillin?
If you miss a dose of Benzathine Penicillin, take it as soon as you remember and then continue as normal. Do not take a double dose to make up for a forgotten dose.
What is the most common side effect of Benzathine Penicillin?
The most common side effect of Benzathine Penicillin is nausea. Other side effects may include vomiting, diarrhea, rash, dizziness, headache, fever, and stomach pain.
Is there anything I should avoid while taking Benzathine Penicillin?
It is generally not advised to drink alcohol while taking Benzathine Penicillin as it can cause further nausea and can increase the risk of side effects. It is also important to avoid taking any other medications without consulting your doctor first.
What should I do if I experience a severe rash while taking Benzathine Penicillin?
If you experience a severe rash while taking Benzathine Penicillin, it is important to stop taking the medication and seek medical advice immediately.
Can I take other medications while taking Benzathine Penicillin?
You should not take any other medications without consulting your doctor or pharmacist first. Benzathine Penicillin can interact with certain medications, such as antacids, probenecid, and certain blood thinners.
Can Benzathine Penicillin be used to treat viral infections?
No, Benzathine Penicillin can only be used to treat bacterial infections. It should not be taken for viral infections, as this can increase the risk of side effects.
What should I do if I experience an upset stomach while taking Benzathine Penicillin?
If you experience an upset stomach while taking Benzathine Penicillin, it is important to speak to your doctor or pharmacist. They may advise you to take an antacid or make other changes to your medication regimen.
Can Benzathine Penicillin cause drowsiness?
Yes, Benzathine Penicillin can cause drowsiness in some people. If you experience drowsiness, it is important to avoid operating machinery or driving until this side effect has passed.
What should I do if I experience a headache while taking Benzathine Penicillin?
If you experience a headache while taking Benzathine Penicillin, it is important to speak to your doctor or pharmacist. They may advise you to take a painkiller or make other changes to your medication regimen.
Is it safe to take Benzathine Penicillin long-term?
Yes, it is usually safe for long-term use if taken as prescribed. However, it is important to discuss any potential risks with your doctor before taking this medication.
Does Benzathine Penicillin affect blood sugar levels?
No, there have been no reports of Benzathine Penicillin affecting blood sugar levels. However, it is important to monitor your blood sugar levels while taking this medication.
Can Benzathine Penicillin affect my kidneys?
Yes, long-term use of Benzathine Penicillin may cause kidney damage. It is important to discuss any potential risks with your doctor before taking this medication.
Can taking Benzathine Penicillin cause yeast infections?
Yes, taking Benzathine Penicillin may increase the risk of developing yeast infections. If you experience any itching, soreness, or irritation, it is important to speak to your doctor as soon as possible.
Can I take Benzathine Penicillin if I have a kidney or liver disease?
Yes, if you have a kidney or liver disease, it is usually safe to take Benzathine Penicillin. However, it is important to discuss any potential risks with your doctor before taking this medication.
Can I take Benzathine Penicillin if I have an allergy to penicillin?
No, if you have an allergy to penicillin, it is not advisable to take Benzathine Penicillin. Speak to your doctor about alternative treatments or to discuss the risks and benefits further.
Can I take Benzathine Penicillin if I am breastfeeding?
It is usually safe for breastfeeding women to take Benzathine Penicillin, however it is important to discuss any potential risks with your doctor before taking this medication.
Can I take Benzathine Penicillin if I am taking other medications?
It is important to tell your doctor or pharmacist about any other medications that you are taking before starting Benzathine Penicillin, as it is not recommended to take Benzathine Penicillin with other medications. Your doctor can advise you on the best course of action.
How long does it take for the effects of Benzathine Penicillin to wear off?
The effects of Benzathine Penicillin usually last for several days after the course of medication has been completed. It is important to finish the course of medication as prescribed to ensure that the infection does not return.
Do I need to avoid any food or drink while taking Benzathine Penicillin?
It is generally not advised to drink alcohol while taking Benzathine Penicillin as it can cause further nausea and can increase the risk of side effects. You do not need to avoid any other food or drink while taking this medication.
Do I need to take any precautions while taking Benzathine Penicillin?
Yes, it is important to take the precautions outlined by your doctor while taking Benzathine Penicillin. This may include avoiding certain activities, such as operating machinery or driving, and avoiding certain medications or alcohol.
Is there any food or medication that I should avoid while taking Benzathine Penicillin?
Yes, it is important to avoid taking other medications without consulting your doctor first, as Benzathine Penicillin can interact with certain medications, such as antacids, probenecid, and certain blood thinners. It is also important to avoid drinking alcohol while taking Benzathine Penicillin.