Azawan

Azawan Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Azawan is a brand name. Its generic name is Azathioprine.

Introduction

Azawan (brand name Imuran) is an immunosuppressive drug used to treat autoimmune diseases and to prevent organ transplant rejection. It works by suppressing the body’s immune system, slowing down its ability to produce antibodies and other immune cells that attack and damage healthy cells, tissues, and organs.

Uses for

Azawan is mainly used to treat autoimmune diseases such as rheumatoid arthritis, Crohn’s disease, ulcerative colitis, and multiple sclerosis. It is also used to help prevent organ transplant rejection.

Mechanism of Action

Azawan works by inhibiting the growth of new immune system cells. It does this by blocking the production of certain amino acids necessary for cell growth and division. Azawan also inhibits the production of other immune system cells that can attack and damage healthy cells.

How Long Does it Take To Work?

It typically takes at least 2 to 3 weeks before the full therapeutic effects of azathioprine are seen. The time frame may vary depending on the individual and the disease being treated.

Absorption

Azawan is absorbed rapidly following oral administration. It is metabolized in the liver and is eliminated mainly through the kidneys.

Route of Elimination

Azawan is primarily eliminated from the body through the urine. Some of the metabolized drug is also excreted in the bile.

Dosage

The usual initial oral dose of Azawan is 2 to 3 mg per kg of body weight per day, divided into two equal doses and taken with food. The dose may be increased by 1 to 2 mg per kg of body weight per day at weekly intervals, up to a maximum dose of 5 to 6 mg per kg of body weight per day.

Administration

Azawan should be taken with meals, preferably at the same time each day. It is also available in tablets, capsules, and liquid forms.

Side Effects

Common side effects of azathioprine include nausea, vomiting, anorexia, hepatitis, jaundice, bone marrow suppression, anemia, and thrombocytopenia.

Toxicity

Azawan can be toxic if taken in high doses. Overdose can cause liver damage, nausea, vomiting, rash, and decreased immunity.

Precautions

Azawan should not be taken by people who are pregnant or nursing, or who have an impaired liver or kidney function. People taking Azawan should also avoid exposure to sunlight, since the drug can increase the risk of sunburn.

Interaction

Azawan may interact with other drugs, including antibiotics, antifungals, anti-parasitics, and some over the counter medications. People taking Azawan should speak with their doctor before taking any new prescription or nonprescription medications.

Disease Interaction

Azawan may worsen existing conditions such as leukemia, lupus, or an infection. It may also increase the risk of developing new conditions, such as cancers and other autoimmune diseases.

Drug Interaction

Azawan may interact with certain drugs, such as barbiturates, phenytoin, carbamazepine, and some antibiotics. People taking Azawan should speak with their doctor before taking any new prescription or non-prescription medications.

Food Interactions

Azawan may interact with certain foods, such as dairy products, citrus juices, and alcoholic beverages. People taking azathioprine should speak with their doctor about any foods that should be avoided.

Pregnancy Use

Azawan has not been studied in pregnant women and should not be used during pregnancy unless the potential benefits outweigh the potential risks. Women who are pregnant or planning to become pregnant should speak to their doctor before taking Azawan.

Lactation Use

Azawan has not been studied in nursing mothers and should not be used while breastfeeding. Women who are breastfeeding or planning to breastfeed should speak to their doctor before taking Azawan.

Acute Overdose

Symptoms of an acute overdose may include nausea, vomiting, rash, decreased immunity, and liver damage. If an overdose is suspected, the person should be taken to an emergency room for evaluation and treatment.

Contraindication

Azawan should not be taken by people who are pregnant or nursing, or who have an impaired liver or kidney function. People with a history of blood disorders, or with a weakened immune system, should speak with their doctor before taking azathioprine.

Use Direction

Azawan should be taken as directed by your doctor. It is typically taken once or twice daily with food. It is important to take Azawan at the same time every day to maintain an even level in your system.

Storage Conditions

Azawan should be stored at room temperature in an airtight container. Keep away from heat, moisture, and direct light.

Volume of Distribution

Azawan has a volume of distribution of 0.310 L/kg.

Half-Life

The elimination half-life of azathioprine is 2.3 hours.

Clearance

The clearance rate of azathioprine is 0.60 mL/min/kg.

Here you find in details version of Azawan

Some Frequently Asked Questions About Azawan

What is Azawan?

Azawan is a medication that is used to treat autoimmune conditions, such as rheumatoid arthritis and Crohn's disease. It is an immune-suppressing drug which works by decreasing the activity of the immune system, helping to slow down the progression of the disease.

What is the usual dosage of Azawan?

The usual dosage of Azawan is 50-250 mg per day, taken orally. The dose should be adjusted according to the response of your condition.

Is there any difference between Azawan and Imuran?

No, they are the same drug. The names are just different brand names for Azawan.

What are the side effects of taking Azawan?

The most common side effects when taking Azawan include nausea, vomiting, loss of appetite, stomach or abdominal pain, headache, dizziness, drowsiness, insomnia, weakness, constipation, and rash. Other less common side effects include hair loss, dry skin, and vision changes.

Is it safe to take Azawan during pregnancy?

It is not recommended to take Azawan during pregnancy due to the potential risks to the fetus. Discuss the risks and benefits of the drug with your doctor before taking it during pregnancy.

What interactions should be avoided when taking Azawan?

Azawan may interact with certain medications, such as blood thinners, steroids, cyclosporine, and tacrolimus, so it is important to discuss potential drug interactions with your doctor before taking Azawan.

Can I take Azawan with other medications?

Yes, you can take Azawan with other medications, but it is important to discuss potential drug interactions with your doctor before taking Azawan with any other medications.

What are the potential complications of taking Azawan?

The potential complications of taking Azawan include liver damage, increased risk of infection, bone marrow suppression, and an increased risk of developing certain types of cancer. Discuss the potential risks with your doctor before taking the medication.

What should I do if I miss a dose of my Azawan?

If you miss a dose of your Azawan, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time for your next dose, skip the missed dose and take it at the usual time. Do not take a double dose to make up for a missed one.

Are there any alternatives to Azawan?

Yes, there are several alternative medications for treating autoimmune conditions, such as cyclosporine, methotrexate, and leflunomide. It is important to discuss the potential risks and benefits of these medications with your doctor before taking them.

What should I do if I experience a side effect while taking Azawan?

If you experience any side effects while taking Azawan, it is important to contact your doctor right away. Do not stop taking Azawan without consulting your doctor first.

How long does it take Azawan to work?

It typically takes several weeks for Azawan to start working and begin having an effect on your condition. The length of time may vary depending on the severity of your condition and the dosage of the drug.

Do I need to take Azawan for the rest of my life?

It is not always necessary to take Azawan for the rest of your life. It is important to discuss this with your doctor so that an individual treatment plan can be devised.

What should I avoid while taking Azawan?

It is important to avoid alcohol consumption while taking Azawan, as it can increase the risk of liver damage. It is also important to avoid exposure to sunlight and UV lights, as this can increase the risk of skin reactions and other side effects. Discuss any other potential risks and precautions with your doctor.

What should I do if I overdose on Azawan?

If you think you have overdosed on Azawan, seek medical help right away. Do not take any other medications without consulting your doctor first.

Can Azawan be used to treat other conditions besides autoimmune diseases?

Azawan may also be used to treat certain skin conditions and some types of cancer, such as lymphoma and dermatomyositis. It is important to discuss any potential risks and benefits of the drug with your doctor before taking it.

How is Azawan supplied?

Azawan is a tablet that is supplied in 25 mg and 50 mg doses. The tablets can be taken orally, or they can be administered as an injection.

What is the recommended storage temperature for Azawan?

Azawan should be stored at room temperature between 15-25°C (59-77°F). It is important to keep this medication away from light, heat, and moisture.

What makes Azawan different from other immunosuppressants?

Azawan is an immunosuppressant drug that works by targeting the immune system and decreasing its activity. This makes it different from other immunosuppressants, which may also target other body systems. It is important to discuss any potential risks and benefits of the drug with your doctor before taking it.

Can I take Azawan if I have certain allergies?

If you have any known allergies, you should discuss them with your doctor before taking Azawan. This is to ensure that the drug will be safe for you to take and that you are not at an increased risk of any allergic reactions.

Does Azawan increase the risk of infection?

Yes, Azawan suppresses the activity of the immune system, which increases the risk of infection. It is important to take any preventative measures you can to avoid getting sick while taking this medication.

Is there a generic version of Azawan available?

Yes, there is a generic version of Azawan available. The name of the generic version is Imuran.

Can I still take Azawan if I have kidney problems?

If you have kidney problems, it is important to discuss them with your doctor before taking Azawan. Your doctor may lower the dosage or adjust the frequency of the medication to ensure that it is safe for you to take.

Can I donate blood while taking Azawan?

No, it is not recommended to donate blood while taking Azawan, as the drug can be passed into the blood supply. Talk to your doctor if you have any questions.

Can I take electrolyte supplements while on Azawan?

Yes, you can take electrolyte supplements while taking Azawan. However, it is important to check with your doctor before taking any supplements, as they could interact with the medication.

What is the recommended time to take Azawan?

It is recommended to take Azawan once per day, in the morning. You can take it with or without food. It is important to take the medication at the same time each day to maintain an even level in your system.

Can I take Azawan if I am pregnant or breastfeeding?

It is not recommended to take Azawan if you are pregnant or breastfeeding. This is because it can be passed from the mother to the baby and can cause harm. Discuss the potential risks and benefits of the drug with your doctor before taking it.

Can Azawan cause liver damage?

Yes, taking Azawan can increase the risk of liver damage. It is important to discuss any potential risks with your doctor before taking this medication.

Can I take a multivitamin while taking Azawan?

Yes, you can take a multivitamin while taking Azawan. However, it is important to check with your doctor before taking any additional supplements, as they could interact with the medication.

What are the long-term effects of taking Azawan?

The long-term effects of taking Azawan can vary, but they can include an increased risk of bone marrow suppression, increased risk of liver damage, and an increased risk of developing certain types of cancers. Discuss any potential long-term effects with your doctor before taking the medication.

Can I take Azawan if I have an infection?

No, it is not recommended to take Azawan if you have an infection, as it can increase the risk of the infection spreading. It is important to discuss any potential infection with your doctor before taking the medication.

Can I take herbal supplements while taking Azawan?

Yes, you can take herbal supplements while taking Azawan. However, it is important to check with your doctor before taking any supplements, as they could interact with the medication.

What happens if I accidentally take too much Azawan?

If you accidentally take too much Azawan, it is important to seek medical help right away. Do not take any other medications without consulting your doctor first.

What should I do if I experience a serious side effect while taking Azawan?

If you experience any serious side effects while taking Azawan, it is important to get medical help right away. Do not stop taking the medication without consulting your doctor first.

What should I do if I experience a rash or other skin reactions while taking Azawan?

If you experience any rash or other skin reactions while taking Azawan, it is important to seek medical help right away. Do not stop taking the medication without consulting your doctor first.

Can Azawan cause weight gain?

Yes, taking Azawan can increase the risk of weight gain. It is important to discuss any potential risks with your doctor before taking the medication.

Is Azawan safe for children?

Azawan is not recommended for children under the age of 6. It is important to discuss the potential risks and benefits of the drug with your doctor before giving it to a child.

Can I take Azawan if I have high blood pressure?

Yes, you can take Azawan if you have high blood pressure. However, it is important to discuss any potential risks with your doctor before taking the medication.

Does Azawan cause dizziness?

Yes, taking Azawan can increase the risk of dizziness. It is important to discuss any potential risks with your doctor before taking the medication.

Does Azawan raise blood sugar levels?

Yes, taking Azawan can increase the risk of high blood sugar levels. It is important to discuss any potential risks with your doctor before taking the medication.

Is it safe to take Azawan if I have heart disease?

It is not recommended to take Azawan if you have heart disease, as the drug can increase the risk of complications. Discuss the potential risks and benefits of the drug with your doctor before taking it.

Can I take Azawan if I have an allergy to other medications?

If you have any known allergies, it is important to discuss them with your doctor before taking Azawan. This is to ensure that the drug will be safe for you to take and that you are not at an increased risk of any allergic reactions.