Astel
Astel Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Astel is a brand name. Its generic name is Telmisartan.
Introduction
Astel is a medication that belongs to the angiotensin-II receptor blocker (ARB) class. It is used to treat high blood pressure (hypertension), heart failure, and other related disorders.Uses
Astel is used to treat hypertension and heart failure. It is also indicated for the prevention of cardiovascular morbidity in high-risk patients, and for reducing the risk of stroke and other major cardiovascular events. It can also be used to prevent kidney damage in diabetic patients.Mechanism of Action
Astel works by blocking the actions of angiotensin-II (a protein that causes blood vessels to constrict) and thereby widening the blood vessels so that the pressure of the blood is reduced.How Long Does it Take to Work?
Generally, the effects of telmisartan can be seen within 2 weeks of starting the medication. However, it may take up to 4 weeks of regular use for the effects of the medication to become fully evident.Absorption
Astel is well absorbed from the gastrointestinal tract with peak plasma concentrations being achieved in 3-4 hours after an oral dose.Route of Elimination
The majority of the telmisartan is eliminated unchanged in the urine, via active tubular secretion.Dosage
The recommended dose of telmisartan is 20-80 mg orally once per day. The dose should be adjusted based on the patient's response and should not exceed 80 mg once daily.Administration
Astel should be taken orally with food or a glass of water, once daily. It is not recommended to crush, chew or split the tablets.Side Effects
Common side effects of telmisartan include dizziness, headache, fatigue, diarrhea, stomach pain, and increased urination. Less common but serious side effects include liver damage, fainting, and elevated blood sugar levels.Toxicity
Astel is relatively safe and well-tolerated. Overdose of telmisartan may cause hypotension (low blood pressure), hyperkalemia (high potassium levels in the blood), and bradycardia (slow heart rate).Precaution
Patients should inform their doctor about any medical history, the use of any other prescription or over-the-counter medications, as well as supplements and vitamins prior to taking telmisartan. Astel should be used with caution in pregnant or breastfeeding women.Interaction
Astel may interact with other medications such as potassium-sparing diuretics, potassium supplements, angiotensin-converting enzyme (ACE) inhibitors (such as lisinopril, enalapril), and nonsteroidal anti-inflammatory drugs (NSAIDs).Disease Interaction
Patients with diabetes, hypertension, congestive heart failure, liver disease, or kidney disease should use telmisartan with caution and be monitored more closely by a doctor.Drug Interaction
Use of telmisartan with certain drugs, including angiotensin-converting enzyme (ACE) inhibitors (such as lisinopril, enalapril), diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), and potassium-sparing agents may increase the risk of adverse effects.Food Interactions
Astel should be taken with food for optimal absorption.Pregnancy Use
Astel should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.Lactation Use
Astel is not recommended for use in breastfeeding mothers as it is excreted in breast milk and may cause adverse reactions in the infant.Acute Overdose
If an overdose of telmisartan is suspected, the patient should be monitored for symptoms of hypotension and hypovolemia (low blood volume). Treatment of overdose involves supportive care, which may include intravenous fluids, sympatomimetic agents (such as epinephrine), and diuretics.Contraindication
Astel is contraindicated in patients with hypersensitivity to any of the ingredients of the medication, severe hepatic impairment, and in patients with biliary cirrhosis.Use Direction
Astel should be used as directed by the doctor. It is generally recommended to take the dose in the morning to avoid it interfering with sleep.Storage Condition
Astel should be stored at room temperature, between 15°C and 30°C. Keep medication away from light, moisture, and heat. Store out of reach of children and pets.Volume of Distribution
Astel has a volume of distribution of 11L/kg.Half Life
The elimination half-life of telmisartan is 24 hours.Clearance
The oral clearance of telmisartan is 1.3 L/hour/kg.Here you find in details version of Astel
Some Frequently Asked Questions About Astel
What is Astel?
Astel is a type of medication used to treat high blood pressure (hypertension) and heart failure. It is known as an angiotensin II receptor blocker, which works by blocking the hormone angiotensin so as to widen blood vessels, helping to reduce blood pressure and improve the flow of blood around the body.
What are the benefits of Astel?
Astel is used to treat high blood pressure (hypertension) and heart failure. It can also help reduce the risk of stroke, heart attack, and cardiac death in patients who have already had cardiovascular events. It is also used to decrease the risk of kidney failure due to diabetes, as well as to reduce stress and fatigue.
How does Astel work?
Astel works by blocking the action of the hormone angiotensin II, which is involved in narrowing of blood vessels. This helps to widen blood vessels, reducing blood pressure and improving the flow of blood around the body.
How long does it take for Astel to work?
It usually takes 4-6 weeks for Astel to start working. The full effect on blood pressure may not be seen for up to 8 weeks after starting treatment.
Is Astel safe?
Astel is generally well tolerated and considered safe for use by most patients, however it should not be taken if you are pregnant, have an allergy to angiotensin II receptor blockers, or have persistent liver problems. Always speak to your doctor before taking any medication.
Who should not take Astel?
Astel should not be taken by pregnant women, those with an allergy to angiotensin II receptor blockers, and those with persistent liver problems. It should also not be taken during breastfeeding.
What are the side effects of Astel?
The most common side effects of Astel are headache, dizziness, and fatigue. Other side effects include nausea, diarrhea, and rash. If any of these side effects become severe, contact your doctor.
What happens if I miss a dose of Astel?
If you miss a dose of Astel, take it as soon as you remember. However, if it is close to the time for your next dose, then skip it and take the next dose as normal. Do not take a double dose to make up for a missed one.
What should I avoid while taking Astel?
Avoid drinking alcohol while taking Astel, as it can increase the risk of side effects. Also, avoid taking other medications or supplements which might interact with Astel. Ask your doctor for a list of medications or supplements to avoid, as some can increase the risk of side effects.
Can I drive or operate heavy machinery while taking Astel?
It is generally safe to drive or operate heavy machinery while taking Astel. However, always speak to your doctor if you experience any dizziness or fatigue while taking this medication, as it could affect your ability to concentrate or react quickly.
What happens if I overdose on Astel?
If you overdose on Astel, seek emergency medical attention. Overdose symptoms may include a rapid heartbeat, difficulty breathing, muscle weakness, light-headedness, and dizziness.
Does Astel interact with any other medications?
Yes, Astel may interact with other medications, including nonsteroidal anti-inflammatory drugs (NSAIDs), diuretics, and certain heart medications. Always tell your doctor about any medications you are taking before starting Astel.
What should I tell my doctor before taking Astel?
Before taking Astel, you should tell your doctor about any existing medical conditions or allergies you have, as well as any medications you are currently taking. This will help to avoid any potential side effects or interactions.
Is there a generic version of Astel available?
Yes, some generic versions of Astel are available. Make sure to speak to your doctor or pharmacist to see if this would be a suitable option for you.
Is Astel available over-the-counter?
No, Astel is only available with a prescription. You will need to talk to your doctor about whether Astel is the right choice for you.
How long do I need to take Astel?
The duration of Astel treatment will depend on why you are taking it, as well as your individual circumstances. Your doctor will be able to advise you on an appropriate course of treatment.
Is Astel safe for long-term use?
Yes, Astel is generally safe for long-term use, but always speak to your doctor about any potential risks. It is also important to be regularly monitored while taking this medication.
Can Astel be taken with other medications?
Yes, Astel can be taken with other medications. However, it is important to talk to your doctor before taking any additional medications, as some may interact with Astel in a harmful way.
Is Astel safe during pregnancy?
No, Astel is not safe during pregnancy and should not be taken by pregnant women. Talk to your doctor about other treatments which may be suitable.
Can I take nonsteroidal anti-inflammatory drugs (NSAIDs) while taking Astel?
No, NSAIDs should not be taken while taking Astel, as they can interact in a harmful way and increase the risk of side effects. Talk to your doctor or pharmacist about other medications which may be suitable.
Can I take Astel if I have kidney problems?
Yes, it is generally safe to take Astel if you have kidney problems. However, always speak to your doctor about potential risks before taking this medication.
Can Astel cause erectile dysfunction?
Astel could potentially cause erectile dysfunction. Contact your doctor if you experience any issues related to your sexual health while taking this medication.
Can Astel cause weight gain?
Astel could potentially cause weight gain in some cases. Consult your doctor if you are concerned about weight gain while taking this medication.
Could Astel cause hair loss?
It is unlikely that Astel would cause hair loss. However, if you notice any changes in your hair while taking Astel, consult your doctor.
Does Astel affect potassium levels?
Astel has been known to increase potassium levels in the blood. It is important to have regular blood tests to monitor your potassium levels while taking this medication.
Can Astel make me sleepy?
Yes, Astel can cause fatigue and dizziness. If this occurs, contact your doctor. Do not drive or operate heavy machinery if you experience this side effect.
Can I take ibuprofen while taking Astel?
No, ibuprofen should not be taken while taking Astel, as it can interact in a harmful way and increase your risk of side effects. Talk to your doctor about other pain relief options.
Is Astel a diuretic?
No, Astel is not a diuretic. It is an angiotensin II receptor blocker which works by blocking the hormone angiotensin II.
Does Astel cause coughing?
Astel could potentially cause coughing in some cases. If you experience coughing while taking this medication, contact your doctor.
Can Astel cause dizziness?
Yes, Astel can cause dizziness in some cases. If you experience dizziness, contact your doctor. Do not drive or operate heavy machinery if you experience this side effect.
Can Astel cause muscle pain?
Yes, Astel could potentially cause muscle pain in some cases. If you experience muscle pain or any other side effects while taking this medication, contact your doctor.
Is Astel a Beta-blocker?
No, Astel is not a Beta-blocker. It is an angiotensin II receptor blocker which works by blocking the hormone angiotensin II.
Can Astel cause high potassium levels?
Yes, Astel has been known to increase potassium levels in the blood. It is important to have regular blood tests to monitor your potassium levels while taking this medication.
Does Astel need to be taken with food?
No, Astel does not need to be taken with food. However, it is important to take it at the same time each day to maintain a consistent level in your bloodstream.
Can Astel cause bloating?
Yes, Astel could potentially cause bloating in some cases. If you experience bloating while taking this medication, contact your doctor.
Should I take Astel if I have diabetes?
Yes, Astel can be taken if you have diabetes. However, always speak to your doctor before taking any medications, as some may interact with one another in a harmful way.
Can I take Astel if I have asthma?
Yes, Astel can be taken if you have asthma. However, always speak to your doctor before taking any medications, as some may interact with one another in a harmful way.
Can Astel cause a sore throat?
Astel could potentially cause a sore throat in some cases. If you experience a sore throat while taking this medication, contact your doctor.
Can Astel cause dehydration?
Yes, Astel could potentially cause dehydration in some cases. If you experience any symptoms of dehydration while taking this medication, contact your doctor.
Is Astel generic or brand name?
Astel is the brand name for the medication. Some generic versions of Astel are available, however always speak to your doctor or pharmacist before taking any generic medications.
Is Astel water soluble?
Yes, Astel is water soluble. This means that it can be absorbed into the bloodstream quickly.