Anthrax Vaccine

Anthrax Vaccine Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Anthrax Vaccine is a brand name. Its generic name is Anthrax vaccine.

Anthrax Vaccine Introduction

Anthrax is a severe infectious disease caused by the bacteria Bacillus anthracis. Anthrax infection can happen through contact with infected animals or contaminated animal by-products. Infection usually occurs through inhalation, ingestion, or through a break in the skin. Anthrax Vaccine is used to help prevent anthrax infection in people where exposure to the bacteria is a risk.

Uses for Anthrax Vaccine

Anthrax Vaccines are used to prevent anthrax in people who are in a high risk category such as: military personnel, laboratory workers handling and exposed to Bacillus anthracis, and individuals who work closely with animals that are infected with or exposed to anthrax.

Mechanism of Action

The anthrax vaccine is a subunit vaccine containing the protective antigen subpart of the bacterium. The protective antigen activates the immune system to produce protective antibodies to help prevent infection with anthrax.

How Long Does It Take to Work?

When given as a primary vaccination series, the anthrax vaccine takes 7 to 12 months to provide full protection. Once the vaccine series is completed, continued protection is provided by annual boosters.

Absorption

Once given intramuscularly, the anthrax vaccine is rapidly absorbed into the bloodstream, resulting in a rapid immune response.

Route of Elimination

The anthrax vaccine is eliminated through the urine and feces.

Dosage

The anthrax vaccine is given as a primary series of three doses at 0, 1 and 6 months, and then annually thereafter.

Administration

The anthrax vaccine is administered intramuscularly on the deltoid muscle.

Side Effects

Side effects of the anthrax vaccine may include:

  • Redness and swelling at the injection site.
  • Fever.
  • Headache.
  • Fatigue.
  • Nausea.
  • Joint pains.
  • Body aches.

Toxicity

No severe or toxic side effects have been observed with the anthrax vaccine at recommended doses.

Precautions

The anthrax vaccine should not be administered to:

  • Individuals with severe allergic reactions to any component of the vaccine.
  • Individuals who are immunosuppressed.
  • Children under the age of 18.
  • Pregnant women.

Interaction

The anthrax vaccine may interact with certain drugs, such as antibiotics or antivirals. It is important to talk to your doctor about any medications you are taking before getting the vaccine.

Disease Interactions

The anthrax vaccine should not be administered to individuals with severe infections or to individuals who have had a recent exposure to anthrax. It is important to talk to your doctor about any recent or ongoing medical conditions before getting the vaccine.

Drug Interactions

The anthrax vaccine may interact with certain drugs, such as antibiotics or antivirals. It is important to talk to your doctor about any medications you are taking before getting the vaccine.

Food Interactions

The anthrax vaccine has no known food or drug interactions.

Pregnancy Use

The anthrax vaccine should not be administered to pregnant women because its safety during pregnancy has not been established.

Lactation Use

The anthrax vaccine should not be administered to lactating women because its safety during lactation has not been established.

Acute Overdose

No reports of acute overdose related to the anthrax vaccine have been reported.

Contraindication

The anthrax vaccine is contraindicated in individuals with a severe allergy to any component of the vaccine, in individuals who are immunosuppressed, in individuals with severe infections, and in individuals who have had a recent exposure to anthrax.

Use Directions

The anthrax vaccine should be administered intramuscularly on the deltoid muscle in a series of three doses at 0, 1 and 6 months, and then annually thereafter.

Storage Conditions

The anthrax vaccine should be stored at 35-45°F (2-7°C) and protected from light.

Volume of Distribution

The volume of distribution of the anthrax vaccine is not known.

Half Life

The half-life of the anthrax vaccine is not known.

Clearance

The clearance of the anthrax vaccine is not known.

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