Antitussin

Antitussin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Antitussin is a brand name. Its generic name is Guaifenesin.

Introduction

Antitussin, also known as glyceryl guaiacolate or glycerol guaiacolate, is an expectorant drug that is used to reduce mucus viscosity in the upper respiratory tract. It has been available over-the-counter (OTC) since the 1950s and is commonly used to treat colds, asthma, and other upper respiratory conditions.

Uses

Antitussin is commonly used to help loosen coughs and congestion caused by the common cold, bronchitis, and respiratory illnesses. It is also used for other conditions such as muscle spasms, menstrual cramps, and other conditions.

Mechanism of Action

Antitussin works by increasing the water content of mucus, thus reducing the viscosity and making it easier to cough it up. It is thought to work by activating mucus-secreting cells. It also increases the amount of time it takes for the mucus to move through the respiratory tract, allowing more time for it to be cleared.

How Long Does it Take to Work?

Antitussin is generally fast-acting, and it can start to work within 15 minutes. Its effects can last for up to 8 hours.

Absorption

Antitussin is rapidly and almost completely absorbed from the gastrointestinal tract. Its effects on mucus production occur almost immediately after administration.

Route of Elimination

Antitussin is eliminated mostly through the urine, although some is eliminated through the feces.

Dosage

Antitussin is available as an oral liquid, tablet, and syrup. The typical dosage for an adult is 200 mg to 400 mg every 4 to 6 hours, with a maximum of 2400 mg per day. For children, the dosage is usually 10 mg/kg/day.

Administration

Antitussin should be taken with a full glass of water. If using the syrup form, it should be taken with food or immediately after a meal. The tablet form should not be chewed or crushed and should be taken with a full glass of fluids.

Side Effects

Antitussin is generally well-tolerated, but it can cause some mild side effects. These include nausea, vomiting, upset stomach, headache, dizziness, and fatigue.

Toxicity

Antitussin is generally considered safe for use and has a low toxicity. There have been no reports of serious toxic effects from taking it.

Precaution

Antitussin should be used with caution in people with kidney, liver, or heart diseases. It is also not recommended for women who are pregnant or breastfeeding.

Interaction

Antitussin can interact with other medications, particularly those that affect the central nervous system, such as sedatives, pain medications, antihistamines, or antidepressants. It is important to tell your healthcare provider about all other medications that you are taking before taking guaifenesin.

Disease Interaction

Antitussin can worsen conditions such as glaucoma, enlarged prostate, kidney or liver disease, or heart disease. People with these conditions should consult with a physician before taking guaifenesin.

Drug Interaction

Food Interaction

Antitussin does not interact with food, however, it should be taken with a full glass of fluids.

Pregnancy Use

Antitussin should be used with caution in pregnant women and be avoided during the first trimester. Safety in pregnant women has not been established. Women who are pregnant should consult with a healthcare provider before taking guaifenesin.

Lactation Use

Antitussin should be used with caution in nursing mothers. It is important to talk to your healthcare provider before taking guaifenesin while breastfeeding.

Acute Overdose

Symptoms of an acute overdose of guaifenesin include nausea, vomiting, abdominal pain, and diarrhea. In severe cases, an overdose can lead to seizures, coma, and death. If you suspect an overdose, contact a poison control center or seek medical help immediately.

Contraindication

Antitussin should not be used in people who are allergic to guaifenesin or any of its ingredients. It should also not be used in people with kidney or liver disease, heart disease, or difficulty in urination due to an enlarged prostate gland.

Use Direction

Antitussin should be taken as directed by your healthcare provider. The typical dosage for an adult is 200 mg to 400 mg every 4 to 6 hours, with a maximum of 2400 mg per day. For children, the dosage is usually 10 mg/kg/day. It should be taken with a full glass of water and should not be chewed or crushed. The syrup form should be taken with food or immediately after a meal.

Storage Condition

Antitussin should be stored at room temperature, away from direct light and moisture, in its original container.

Volume of Distribution

Antitussin is not distributed widely throughout the body, as it is mostly eliminated through the urine.

Half Life

The half-life of guaifenesin is approximately 0.7 to 1.2 hours.

Clearance

Antitussin is eliminated mainly through the urine, and it has a clearance rate of approximately 4 L/h/kg.

Here you find in details version of Antitussin

Some Frequently Asked Questions About Antitussin

What is Antitussin?

Antitussin is an expectorant, a type of medication that helps thin out and loosen mucus in the airways, making it easier to cough it out.

What are the uses of Antitussin?

Antitussin is used to help reduce chest congestion caused by the common cold, infections, or allergies.

How is Antitussin taken?

Antitussin comes in tablet, capsule, or liquid form, and is taken by mouth, usually up to three to four times daily.

What are the common side effects of Antitussin?

Common side effects of Antitussin include nausea, vomiting, dizziness, drowsiness, restlessness, and stomach upset.

How soon will I start to see the benefits of Antitussin?

It may take several days of taking Antitussin regularly before its full effect is seen.

Is Antitussin safe to use while pregnant or breastfeeding?

Antitussin use while pregnant or breastfeeding is generally considered safe as long as it is taken as directed. However, you should consult your doctor before taking Antitussin if you are pregnant or breastfeeding.

Can I take Antitussin with other medications?

Antitussin can interact with certain medications. Thus, you should always inform your doctor or pharmacist before taking any other medications while taking Antitussin.

What should I do if I miss a dose of Antitussin?

If you miss a dose of Antitussin, take it as soon as you remember. If it is close to the time for the next dose, skip the missed dose and resume the regular dosing schedule.

Is Antitussin habit-forming?

Antitussin is not known to be habit-forming when taken as prescribed and directed.

Can children take Antitussin?

Antitussin is generally considered safe for children older than 4 years of age. For children younger than 4, it should only be used with the advice of a doctor.

What happens if I overdose on Antitussin?

If you overdosed on Antitussin, seek medical attention right away.

Are there food or drinks I should avoid while taking Antitussin?

You should not take Antitussin with alcohol or products containing alcohol, such as cold or cough medicines. Additionally, it is best to avoid caffeinated foods and drinks while taking Antitussin.

Does Antitussin expire?

Yes, Antitussin has an expiration date and should not be used past this date.

Can I drink alcohol while taking Antitussin?

You should not drink alcohol while taking Antitussin, as this can increase the risk of side effects.

Should I take Antitussin with food?

Antitussin can be taken with or without food, however, it is recommended to take it after meals or snacks if it causes stomach upset.

Can Antitussin cause drowsiness?

Antitussin can cause drowsiness, however this is generally mild and should not interfere with driving or operating machinery.

Can Antitussin be crushed or chewed?

Antitussin tablets should not be crushed or chewed as this could cause too much of the drug to be released at once.

Is Antitussin an antibiotic?

No, Antitussin is not an antibiotic. It is an expectorant, a type of medication that helps thin out mucus, making it easier to cough out.

Does Antitussin affect birth control?

Antitussin is not known to affect birth control. However, it is best to consult your doctor before taking any medication if you are using birth control.

Is Antitussin available without a prescription?

Yes, Antitussin is available without a prescription in most countries. However, it is best to check with your local pharmacy.

Does Antitussin interact with other medications?

Antitussin can interact with certain medications. You should always inform your doctor or pharmacist before taking any other medications while taking Antitussin.

Is Antitussin habit-forming?

No, Antitussin is not habit-forming when taken as prescribed and directed.

Does Antitussin have any long-term effects on the body?

Antitussin is generally considered to be safe and has no known long-term effects when taken as prescribed and directed.

Can I take Antitussin with ibuprofen?

Antitussin can interact with ibuprofen. It is best to consult your doctor before taking ibuprofen and Antitussin together.

Can Antitussin be taken with acetaminophen?

Antitussin can be taken with acetaminophen but it is best to consult your doctor or pharmacist before taking the two medications together.

Can Antitussin cause a sore throat?

Antitussin is not known to cause a sore throat. However, it can be a symptom of an underlying condition.

Can Antitussin be used to treat asthma?

No, Antitussin is not used to treat asthma. It is used to treat chest congestion caused by the common cold, infections, or allergies.

Where can I find more information on Antitussin?

You can find more information about Antitussin on the internet or by speaking to your doctor or pharmacist.

Are there any natural remedies for chest congestion?

Yes, natural remedies such as steam inhalation, warm liquids, and honey may help to reduce chest congestion.

How should I store Antitussin?

Antitussin should be stored at room temperature away from heat, light, and moisture.

Is Antitussin safe for cats?

Antitussin is not generally recommended for use in cats as it is not approved for use in cats. It is best to consult your veterinarian before giving any type of medication to your cat.

What is the best way to take Antitussin to get the most benefit?

For the best results, it is important to take Antitussin as directed by your doctor or pharmacist. Try to take it at the same times each day and avoid drinking alcohol or caffeinated drinks while taking it.

Can I take Antitussin with my other medications?

You should always inform your doctor or pharmacist before taking any other medications while taking Antitussin, as it may interact with certain medications.

What should I do if I experience any side effects from Antitussin?

If you experience any serious side effects such as difficulty breathing or confusion, seek medical attention right away. For milder side effects, such as nausea or dizziness, it is best to talk to your doctor to determine if the medication needs to be adjusted.

Can I take Antitussin if I have kidney problems?

Antitussin should be taken with caution if you have kidney problems, as it can cause increased levels of creatinine and BUN in blood tests.

Can Antitussin be taken to treat a cough?

Yes, Antitussin can be taken to help reduce chest congestion caused by a cough.

Are there any alternatives to Antitussin for treating chest congestion?

Yes, other medications such as decongestants or antihistamines may also be used to treat chest congestion.

Can Antitussin cause an increase in blood sugar levels?

Antitussin is not known to increase blood sugar levels. However, people with diabetes should monitor their blood sugar levels closely while taking Antitussin.

Does Antitussin interact with any vitamins or supplements?

Antitussin can interact with certain vitamins and supplements. You should always inform your doctor or pharmacist before taking any vitamins or supplements while taking Antitussin.

Can I take Antitussin while breastfeeding?

Antitussin use while breastfeeding is generally considered safe as long as it is taken as directed. However, you should consult your doctor before taking Antitussin if you are breastfeeding.