Anafortan Plus
Anafortan Plus Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Anafortan Plus is a brand name. Its generic name is Phloroglucinol + Trimethylphloroglucinol.
Anafortan Plus
Anafortan Plus is a combination of two active ingredients used in a variety of medications. It is made up of two derivatives of phloroglucinol, which is a natural compound found in various plants and fungi. This combination medication is typically used to treat bacterial infections of the skin, nose, throat, and urinary tract.
Uses For
Anafortan Plus is used to treat bacterial infections of the skin, nose, throat, and urinary tract. This combination medication can also be used to treat mild to moderate acne.
Mechanism of Action
Anafortan Plus has an antimicrobial action due to its ability to inhibit the synthesis of essential bacterial enzymes. It binds to the enzyme DNA gyrase, which is an essential enzyme for the structure and maintenance of bacterial DNA. This leads to disruptions in bacterial growth and reproduction. Additionally, it binds to some membrane components, making it difficult for bacteria to survive.
How Long Does It Take To Work?
It typically takes about one to two weeks for Anafortan Plus to take effect and reduce symptoms of the infection. In some cases, it may take up to four weeks for the full benefits of the medication to be realized.
Absorption
Anafortan Plus is rapidly absorbed from the gastrointestinal tract. It is rapidly and extensively metabolized in the liver.
Route of Elimination
Anafortan Plus is eliminated primarily by the kidneys through the urine. Trace amounts of the drug may also be found in the bile.
Dosage
The dosage of Anafortan Plus depends on the condition being treated and the individual patient's response to the medication. The usual adult dosage is one tablet three times per day, but a healthcare provider may prescribe a different dosage depending on the patient's specific needs.
Administration
Anafortan Plus should be taken on an empty stomach at least one hour before or two hours after meals. The tablets should be swallowed whole with a full glass of water.
Side Effects
The most common side effects associated with Anafortan Plus include nausea, vomiting, stomach pain, and diarrhea. Other side effects may include headache, dizziness, skin rash, itching, and joint pain. In rare cases, a severe reaction known as a hypersensitivity reaction may occur. It is important to contact a healthcare provider immediately if any of these side effects are experienced.
Toxicity
Anafortan Plus is not expected to be toxic if taken at recommended doses. At higher doses, there may be an increased risk of serious side effects and other complications.
Precautions
Patients who are pregnant or breastfeeding should not take Anafortan Plus. Before taking this medication, patients should tell their healthcare provider about all of their medical conditions, as well as all other medications, supplements, and vitamins they are taking. This medication should not be used by patients who have an allergy or sensitivity to phloroglucinol or Trimethylphloroglu cinol.
Interactions
Anafortan Plus may interact with other medications, supplements, and vitamins. Patients should always tell their healthcare provider and pharmacist about all medications, supplements, and vitamins they are taking to avoid any potential interactions. Additionally, they should avoid taking this with antacids, as it can decrease the absorption of the medication.
Disease Interactions
Anafortan Plus can interact with certain diseases, including kidney and liver diseases. Patients with these conditions should consult a healthcare provider before taking this medication.
Drug Interactions
Anafortan Plus may interact with other medications such as warfarin, diazepam, and phenytoin. It can also interact with some antibiotics, diuretics, and antifungals. Patients should always tell their healthcare provider and pharmacist about all medications they are taking.
Food Interactions
Anafortan Plus should not be taken with food, as it can decrease the absorption of the medication. Additionally, it should not be taken with antacids or dairy products, as this can also decrease absorption.
Pregnancy Use
Anafortan Plus should not be used during pregnancy, as it is not known if it is safe for the fetus. It should only be used if the potential benefit outweighs the potential risk.
Lactation Use
Anafortan Plus is not recommended for use in breastfeeding women, as it is not known if it is present in breast milk.
Acute Overdose
An acute overdose of Anafortan Plus can cause severe side effects. If an overdose is suspected, medical attention should be sought immediately.
Contraindication
Anafortan Plus is contraindicated in patients with an allergy or sensitivity to phloroglucinol or Trimethylphloroglucinol.
Use Direction
Anafortan Plus should be taken on an empty stomach at least one hour before or two hours after meals. The tablets should be swallowed whole with a full glass of water.
Storage Condition
Anafortan Plus should be stored at room temperature in a dry, protected area away from light and out of the reach of children.
Volume of Distribution
The volume of distribution of Anafortan Plus is approximately 27 L/kg.
Half Life
The half-life of Anafortan Plus is approximately 14 hours.
Clearance
The clearance of Anafortan Plus is approximately 0.6 L/hr/kg.
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