Sinaxamol

Sinaxamol Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Sinaxamol is a brand name. Its generic name is Orphenadrine + Paracetamol.

Introduction

Sinaxamol is a combination of two medication used to treat pain and stiffness associated with muscle spasms. It is composed of orphenadrine, a muscle relaxant, and paracetamol, an analgesic and antipyretic.

Uses for

Sinaxamol is used to help relieve pain and stiffness associated with muscle spasms. It may also be prescribed to reduce fever and treat certain types of arthritis.

Mechanism of Action

Orphenadrine works by blocking the action of certain neurotransmitters in the brain that can cause muscle spasms, while paracetamol works by reducing the production of prostaglandins, the chemicals in the body that cause pain and inflammation.

How Long Does It Take to Work

The effects of orphenadrine + paracetamol typically begin to take effect within 30 minutes of taking the medication.

Absorption

Orphenadrine + paracetamol is rapidly and almost completely absorbed from the gastrointestinal tract, with peak plasma concentrations occurring after about 1-2 hours. The bioavailability of orphenadrine + paracetamol is approximately 100%.

Route of Elimination

Orphenadrine + paracetamol is eliminated via the kidneys and is metabolized to an active metabolite.

Dosage

The dosage of orphenadrine + paracetamol should be determined by your doctor, as it will depend on several factors such as your age, weight, other medications you are taking, and other medical conditions you may have. Typical dosage is 1-2 tablets, 2-4 times a day.

Administration

Orphenadrine + paracetamol should be taken orally. It can be taken either with or without food.

Side Effect

Common side effects of orphenadrine + paracetamol include nausea, dizziness, headache, upset stomach, and dry mouth.

Toxicity

Excessive doses of paracetamol can be toxic and lead to liver damage. If you take more than the recommended dosage of orphenadrine + paracetamol, seek medical attention immediately.

Precaution

Orphenadrine + paracetamol should not be used by people with certain medical conditions, such as kidney disease, stomach or intestinal ulcers, liver disease, alcoholism, or those taking certain medications, such as anticholinergics, MAO inhibitors, tricyclic antidepressants, or diuretics.

Interaction

Orphenadrine + paracetamol may interact with certain other medications, including anticholinergics, MAO inhibitors, tricyclic antidepressants, diuretics, levodopa, and certain antibiotics.

Disease Interaction

Orphenadrine + paracetamol may interact with certain conditions, such as epilepsy, diabetes, and thyroid diseases.

Drug Interaction

Orphenadrine + paracetamol may interact with other drugs, such as alcohol, barbiturates, and opiates.

Food Interactions

The absorption of orphenadrine + paracetamol may be affected if it is taken with certain foods. It should not be taken with dairy products, including milk, cheese, and yogurt. Additionally, it should not be taken with citrus juices or antacids containing aluminum or magnesium.

Pregnancy Use

Orphenadrine + paracetamol is not recommended for use during pregnancy.

Lactation Use

Orphenadrine + paracetamol is not recommended for use during breastfeeding.

Acute Overdose

Overdoses of orphenadrine + paracetamol can cause excessive sedation, hypotension, confusion, and respiratory depression. Seek emergency medical attention if you suspect an overdose.

Contraindication

Orphenadrine + paracetamol should not be used in people who are hypersensitive to one or both of the ingredients, or those with glaucoma, urinary retention, or impaired kidney or liver function.

Use Direction

Orphenadrine + paracetamol should be taken as directed by your doctor. Do not exceed the recommended dose or take it for longer than prescribed.

Storage Condition

Orphenadrine + paracetamol should be stored in a cool, dry place at room temperature. Do not store it in direct sunlight or in the refrigerator.

Volume of Distribution

The volume of distribution of orphenadrine + paracetamol ranges from 0.9 to 10 L/kg, depending on age, weight, and other factors.

Half Life

The half-life of orphenadrine + paracetamol is approximately 2-3 hours.

Clearance

The clearance rate of orphenadrine + paracetamol is approximately 1.2 L/hr/kg.

Here you find in details version of Sinaxamol

Some Frequently Asked Questions About Sinaxamol

What are the primary uses of Orphenadrine & Paracetamol tablets?

Orphenadrine & Paracetamol are primarily used as pain relievers and to reduce fever.

What is the active ingredient in Orphenadrine & Paracetamol?

The active ingredient in Orphenadrine & Paracetamol is orphenadrine citrate and Paracetamol.

What is the difference between Orphenadrine and Paracetamol?

Orphenadrine is a muscle relaxant, while Paracetamol is a pain reliever and fever reducer.

What are the side effects of Orphenadrine & Paracetamol?

The most common side effects of Orphenadrine & Paracetamol include nausea, dizziness, drowsiness, and headache.

Can Orphenadrine & Paracetamol be taken with other medications?

Yes, Orphenadrine & Paracetamol can be taken with other medications, but please consult with your physician or healthcare professional for advice before taking it.

Can I buy Orphenadrine & Paracetamol over the counter?

Yes, Orphenadrine & Paracetamol are available over the counter in most pharmacies.

Can I take Orphenadrine & Paracetamol while pregnant or breastfeeding?

No, you should not take Orphenadrine & Paracetamol while pregnant or breastfeeding without first consulting your physician or healthcare professional for advice.

How long does Orphenadrine & Paracetamol take to work?

The effects of Orphenadrine & Paracetamol can usually be felt within 30 minutes of taking the medication.

What should I do if I forget to take Orphenadrine & Paracetamol?

If you forget to take Orphenadrine & Paracetamol, take your regular dose as soon as you remember and then continue with your regular dosage schedule.

What is the recommended dosage of Orphenadrine & Paracetamol?

The recommended dose of Orphenadrine & Paracetamol is one tablet up to four times a day depending on the severity of the pain.

Can I take Orphenadrine & Paracetamol with alcohol?

No, you should not take Orphenadrine & Paracetamol with alcohol. Drinking alcohol with Orphenadrine & Paracetamol can increase the risk of serious side effects.

Can I take Orphenadrine & Paracetamol if I have a history of liver or kidney disease?

No, you should not take Orphenadrine & Paracetamol if you have a history of liver or kidney disease without first consulting your physician or healthcare professional for advice.

Can I take Orphenadrine & Paracetamol if I have a history of stomach ulcers?

No, you should not take Orphenadrine & Paracetamol if you have a history of stomach ulcers without first consulting your physician or healthcare professional for advice.

Can I take Orphenadrine & Paracetamol if I am taking other medications?

Yes, Orphenadrine & Paracetamol can be taken with other medications, but please consult with your physician or healthcare professional for advice before taking it.

What should I do if I experience adverse effects from Orphenadrine & Paracetamol?

If you experience any adverse effects from Orphenadrine & Paracetamol, please stop taking the medication immediately and contact your physician or healthcare professional for advice.

Does Orphenadrine & Paracetamol have any interactions with other drugs?

Yes, Orphenadrine & Paracetamol can interact with other drugs, so please consult with your physician or healthcare professional for advice before taking it if you are taking any other medications.

What should I do if I overdose on Orphenadrine & Paracetamol?

If you overdose on Orphenadrine & Paracetamol, please contact your physician or healthcare professional for medical advice immediately.

Is Orphenadrine & Paracetamol safe for children?

No, Orphenadrine & Paracetamol is not recommended for use in children under 12 years of age.

Should I take Orphenadrine & Paracetamol with food or without food?

Orphenadrine & Paracetamol can be taken with or without food.

Can I take Orphenadrine & Paracetamol if I have high blood pressure?

Yes, Orphenadrine & Paracetamol are safe to take if you have high blood pressure, but please consult with your physician or healthcare professional for advice before taking it.

Can Orphenadrine & Paracetamol be taken long-term?

No, Orphenadrine & Paracetamol should not be taken for more than a few days at a time without first consulting your physician or healthcare professional for advice.

How long does it take for Orphenadrine & Paracetamol to leave the body?

Orphenadrine & Paracetamol is usually eliminated from the body within 6-8 hours.

What should I do if I miss a dose of Orphenadrine & Paracetamol?

If you miss a dose of Orphenadrine & Paracetamol, take your regular dose as soon as you remember and then continue with your regular dosage schedule.

What should I do if I accidentally take too much Orphenadrine & Paracetamol?

If you accidentally take too much Orphenadrine & Paracetamol, please contact your physician or healthcare professional for medical advice immediately.

Is Orphenadrine & Paracetamol addictive?

No, Orphenadrine & Paracetamol are not known to be addictive.

Does Orphenadrine & Paracetamol cause drowsiness?

Yes, Orphenadrine & Paracetamol can cause drowsiness, so it is advised to take the medication at bedtime or before activities that may cause you to be drowsy.

Can I take Orphenadrine & Paracetamol if I am taking blood thinners?

No, you should not take Orphenadrine & Paracetamol if you are taking blood thinners without first consulting your physician or healthcare professional for advice.

Does Orphenadrine & Paracetamol have any interactions with other supplements or vitamins?

Yes, Orphenadrine & Paracetamol can interact with certain supplements and vitamins, so please consult with your physician or healthcare professional for advice before taking it if you are taking any other supplements or vitamins.

What is the shelf-life of Orphenadrine & Paracemol tablets?

The shelf-life of Orphenadrine & Paracetamol tablets is two years.

Is Orphenadrine & Paracetamol available in generic form?

Yes, Orphenadrine & Paracetamol is available in generic form.

Can I take Orphenadrine & Paracetamol if I am taking corticosteroids?

No, you should not take Orphenadrine & Paracetamol if you are taking corticosteroids without first consulting your physician or healthcare professional for advice.

Does Orphenadrine & Paracetamol cause any allergic reactions?

Yes, Orphenadrine & Paracetamol can cause allergic reactions, so please consult with your physician or healthcare professional for advice before taking it if you have any known allergies.

Is Orphenadrine & Paracetamol safe for the elderly?

Yes, Orphenadrine & Paracetamol are generally safe for use in the elderly, but please consult with your physician or healthcare professional for advice before taking it.

Can Orphenadrine & Paracetamol be taken with other anti-inflammatory drugs?

Yes, Orphenadrine & Paracetamol can be taken with other anti-inflammatory drugs, but please consult with your physician or healthcare professional for advice before taking it.

Does Orphenadrine & Paracetamol cause any change in mood?

Yes, Orphenadrine & Paracetamol can cause changes in mood, so it is advised not to operate heavy machinery or drive while taking the medication.

Can I take Orphenadrine & Paracetamol if I am taking antibiotics?

Yes, Orphenadrine & Paracetamol can be taken with antibiotics, but please consult with your physician or healthcare professional for advice before taking it.

Does Orphenadrine & Paracetamol cause any changes in blood pressure?

Yes, Orphenadrine & Paracetamol can cause changes in blood pressure, so please consult with your physician or healthcare professional for advice before taking it if you have any known heart conditions.

What should I avoid while taking Orphenadrine & Paracetamol?

You should avoid drinking alcohol or engaging in activities that require you to be alert, such as operating heavy machinery or driving, while taking Orphenadrine & Paracetamol.

Can Orphenadrine & Paracetamol be used for reducing inflammation?

Yes, Orphenadrine & Paracetamol can be used for reducing inflammation when taken in combination with other anti-inflammatory medications.

Can Orphenadrine & Paracetamol be taken long-term for chronic pain?

No, Orphenadrine & Paracetamol should not be taken long-term for chronic pain without first consulting your physician or healthcare professional for advice.

Should I take Orphenadrine & Paracetamol on an empty stomach or with food?

Orphenadrine & Paracetamol can be taken with or without food.

Can Orphenadrine & Paracetamol be used to treat headaches?

Yes, Orphenadrine & Paracetamol can be used to treat headaches when taken in combination with other pain relievers.

Are Orphenadrine & Paracetamol safe for pets?

No, Orphenadrine & Paracetamol is not safe for pets and should not be given to them without first consulting a veterinarian.