Allergopos N

Allergopos N Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Allergopos N is a brand name. Its generic name is Antazolin + Tetryzoline.

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Introduction

Antazoline + Tetryzoline is a combination of two drugs used to treat eye allergies. It is a combination of a histamine-like drug known as tetryzoline and an antihistamine known as antazoline. This combination is often used to relieve symptoms of seasonal allergies such as redness, itching and watery eyes.

Uses

Antazoline + Tetryzoline combination is used for the relief of symptoms associated with allergic conjunctivitis such as red, itchy and watery eyes. It can also be used to treat other eye allergies such as allergic rhinitis.

Mechanism of Action

Tetryzoline is a histamine-like drug that works by narrowing the blood vessels in the eyes. Antazoline is an antihistamine that blocks histamine at the H1 receptor, which is involved in the allergic process. By blocking histamine, antazoline relieves the itching, redness and tearing that commonly accompanies allergic conjunctivitis.

How Long Does it Take to Work?

The effects of Antazoline + Tetryzoline can be seen within 30 minutes of administration. The maximum effect of the drug is usually felt within 4 to 6 hours.

Absorption

When the Antazoline + Tetryzoline combination is administered as eye drops, it is readily absorbed from the surface of the eye. About 95% of the drug is absorbed in the first 6 hours after administration.

Route of Elimination

Antazoline + Tetryzoline is eliminated mainly by the kidneys. Most of the drug is excreted in the form of metabolites in the urine.

Dosage

The recommended dosage of Antazoline + Tetryzoline for adults is two drops in the affected eye(s) up to three times a day. For children, the recommended dosage is one drop in the affected eye(s) up to three times a day. Do not wear contact lenses while using this medication.

Administration

The usual route of administration of Antazoline + Tetryzoline is ocular. This medication is usually administered as eye drops. The patient should tilt their head back and instill one or two drops of the medication in the affected eye(s). After administration the patient should gently close their eyes for a few minutes before opening them again.

Side-Effect

Dizziness, vision changes, blurred vision, headache, dry eyes, and burning/stinging in the eyes are the most common side-effects of Antazoline + Tetryzoline. If these side-effects persist for a long time or become more severe, contact a doctor.

Toxicity

Antazoline + Tetryzoline combination is a relatively safe drug with no known toxicity. However, accidental overdosage can lead to increased side-effects or even serious toxicity. In such cases, the patient should seek immediate medical attention.

Precaution

It is important to read the instructions carefully before using Antazoline + Tetryzoline. This medication should not be used by pregnant or lactating women. Patients should also inform their doctor about any other medications they are taking as these can interact with the drug and cause unpleasant or harmful side-effects.

Interaction

Antazoline + Tetryzoline may interact with other drugs. Drugs that interact with this medication include MAO inhibitors, anti-seizure medications, antidepressants, and antihistamines. It is important to tell the doctor about all medications being taken before starting this medication.

Disease Interaction

Antazoline + Tetryzoline may interact with certain medical conditions such as glaucoma, asthma or other breathing problems, prostate enlargement, high blood pressure, an overactive thyroid, diabetes, chronic heart failure and seizures.

Drug Interaction

Antazoline + Tetryzoline may interact with certain drugs such as ibuprofen, aspirin, ketoconazole, antacids, naproxen, steroids, and cimetidine. It is important to inform the doctor about all medications being taken before starting this medication.

Food Interactions

No known food interactions have been reported for the Antazoline + Tetryzoline combination.

Pregnancy Use

Antazoline + Tetryzoline should not be used during pregnancy as it can have adverse effects on the developing fetus. It is best to check with a doctor before taking this medication.

Lactation

Antazoline + Tetryzoline should not be used while breastfeeding as it can pass into the breast milk and cause harm to the baby. It is best to check with a doctor before taking this medication.

Acute Overdose

Overdose of Antazoline + Tetryzoline can lead to serious and potentially life-threatening side-effects. If an overdose is suspected, seek immediate medical attention or call the Poison Control Center at 1-800-222-1222.

Contraindication

Antazoline + Tetryzoline should not be used by patients with known hypersensitivity to either of the two components. Caution should be used in patients with glaucoma or other eye diseases.

Use Direction

The patient should read the instructions carefully before using this medication. Always use the eye dropper that is supplied with the medication. Tilt the head back and put one or two drops in the affected eye(s). Close the eye(s) for a few minutes and gently press the sides of the nasal bridge with a finger. Do not touch the container tip to the eye.

Storage Condition

Antazoline + Tetryzoline should be stored at room temperature and should be kept away from heat and direct sunlight. Do not toss this medication out with used tissues.

Volume of Distribution

The volume of distribution of Antazoline + Tetryzoline is unknown.

Half-Life

The half-life of Antazoline + Tetryzoline is about 4 hours.

Clearance

The clearance of Antazoline + Tetryzoline is unknown.

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