Acide Tiludronique
Acide Tiludronique Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Acide Tiludronique is a brand name. Its generic name is Tiludronic acid.
Acide Tiludronique introduction
Acide Tiludronique is an oral phosphonate drug belonging to the bisphosphonate class of drugs. It works by inhibiting bone resorption and decreasing bone turnover. It has been approved by the Food and Drug Administration (FDA) for the treatment of osteoporosis in postmenopausal women. It is also used to treat Paget’s Disease.
Acide Tiludronique uses
Acide Tiludronique is used to treat osteoporosis in postmenopausal women. It is also used to treat Paget’s Disease.
Acide Tiludronique mechanism of action
Acide Tiludronique works by inhibiting bone resorption, decreasing bone turnover and increasing bone mineral density. It works by slowing down the activity of certain cells in the body, called osteoclasts, which are responsible for breaking down bone. By inhibiting osteoclasts, Acide Tiludronique helps to maintain strong, healthy bones.
How long does it take for Acide Tiludronique to work?
It usually takes 12 to 18 months for the full effects of Acide Tiludronique to be seen. However, some patients may notice a decrease in symptoms, such as joint pain and stiffness, within the first few weeks of treatment.
Acide Tiludronique absorption
Acide Tiludronique is completely absorbed in the intestines. About 90% of an oral dose is absorbed in the intestines and is distributed to the skeletal system. About 10% is excreted in the urine unchanged.
Acide Tiludronique route of elimination
Acide Tiludronique is mainly excreted in the urine unchanged, with the remainder being metabolized to its ammonium salt. About 5-10% of an oral dose is excreted unchanged in the urine.
Acide Tiludronique dosage
The recommended dosage of Acide Tiludronique is 4mg once daily after a test meal. It is usually taken after breakfast or the first main meal of the day. It can be taken with or without food.
Acide Tiludronique administration
Acide Tiludronique should be taken as directed by a doctor. It should be taken first thing in the morning, after eating a light meal. The tablet should be swallowed whole with a full glass of water. Do not chew, break or crush the tablet.
Acide Tiludronique side effects
Common side effects of Acide Tiludronique include nausea, vomiting, abdominal pain, constipation, diarrhea, and headache. Other possible side effects include dizziness, muscle pain, bone and joint pain, flu-like symptoms, and fatigue.
Acide Tiludronique toxicity
Acide Tiludronique has been reported to cause mild gastrointestinal irritation and is generally considered to be safe for short-term use. However, it should be used with caution in patients with liver or kidney impairment.
Acide Tiludronique precaution
Patients should not take Acide Tiludronique if they are allergic to any of its components. Patients taking other medications should consult with their healthcare provider before taking Acide Tiludronique. Pregnant and nursing women should also speak to their healthcare provider before taking Acide Tiludronique.
Acide Tiludronique interaction
Acide Tiludronique may interact with other medications, including anticoagulants, antibiotics, and oral anti-diabetics. It may also interact with non-steroidal anti-inflammatory drugs (NSAIDs), salicylates, and diuretics. Patients taking any of these medications should talk to their healthcare provider before taking Acide Tiludronique.
Acide Tiludronique disease interaction
Acide Tiludronique should not be used in patients with kidney or liver impairment. It also should not be used in patients with severe hypocalcemia or low vitamin D levels. Patients with these conditions should speak to their healthcare provider before taking Acide Tiludronique.
Acide Tiludronique drug interaction
Acide Tiludronique may interact with other medications, including anticoagulants, antibiotics, and oral anti-diabetics. It may also interact with non-steroidal anti-inflammatory drugs (NSAIDs), salicylates, and diuretics. Patients taking any of these medications should talk to their healthcare provider before taking Acide Tiludronique.
Acide Tiludronique food interactions
Acide Tiludronique may interact with certain foods, including dairy products, antacids, and mineral supplements. Patients should avoid taking these types of foods at least two hours before or after taking Acide Tiludronique.
Acide Tiludronique pregnancy use
Acide Tiludronique is not recommended for use during pregnancy. It may cause serious harm to the unborn baby. Patients should consult with their doctor before taking Acide Tiludronique if they are pregnant or plan to become pregnant.
Acide Tiludronique lactation use
Acide Tiludronique is not recommended for use during breastfeeding. It may cause serious harm to the baby. Patients should consult with their doctor before taking Acide Tiludronique if they are breastfeeding or plan to breastfeed.
Acide Tiludronique acute overdose
An overdose of Acide Tiludronique is unlikely to cause serious harm. If an overdose is suspected, patients should seek immediate medical attention. Common symptoms of Acide Tiludronique overdose may include nausea, vomiting, and abdominal pain.
Acide Tiludronique contraindication
Acide Tiludronique should not be used in patients who are allergic to any of its components, or in patients with kidney or liver impairment. Patients with severe hypocalcemia or low vitamin D levels should also not use Acide Tiludronique.
Acide Tiludronique use directions
Acide Tiludronique should be taken as directed by a doctor. It should be taken first thing in the morning, after eating a light meal. The tablet should be swallowed whole with a full glass of water. Do not chew, break or crush the tablet.
Acide Tiludronique storage condition
Acide Tiludronique should be stored at room temperature, away from direct light and moisture. Keep it out of the reach of children.
Acide Tiludronique volume of distribution
The volume of distribution of Acide Tiludronique is not known.
Acide Tiludronique half life
The half-life of Acide Tiludronique is approximately 24 hours.
Acide Tiludronique clearance
Acide Tiludronique is cleared primarily by the kidneys. About 5-10% of an oral dose is excreted unchanged in the urine.
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