Acef Lb Dt

Acef Lb Dt Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Acef Lb Dt is a brand name. Its generic name is Cefpodoxime + Lactic Acid.

Introduction

Cefpodoxime and Lactic Acid are two separate medicines that are combined together to treat bacterial infections. Cefpodoxime belongs to a class of drugs known as cephalosporin antibiotics and works by killing bacteria or preventing their growth by preventing them from developing the cell walls that are necessary for their survival. Lactic Acid is an organic acid found naturally in milk, and works together with cefpodoxime to treat infections by balancing the pH levels of the area and decreasing the intensity of the immune response.

Uses

Cefpodoxime and Lactic Acid are most commonly used to treat bacterial infections of the ears, skin, urinary tract, and respiratory system. It is also used to treat acute gonorrhea infections, as well as some sexually transmitted diseases like chlamydia and mycoplasma. Cefpodoxime and Lactic Acid combination is also used to prevent and treat bacterial endocarditis.

Mechanism of Action

Cefpodoxime works by disrupting the bacterial cell walls, which stops the bacteria from making new cell walls and consequently makes them unable to multiply and grow. Lactic Acid helps to increase the concentration of cefpodoxime at the infection site by neutralizing the pH level and reducing inflammation.

How Long Does it Take to Work?

The time it takes for cefpodoxime and lactic acid to take effect depends on the severity of the infection being treated. Generally, it can start working within 24-48 hours of taking the medication, however it may take up to several days or even weeks to see full improvement.

Absorption

When taken orally, Cefpodoxime is rapidly and almost completely absorbed from the gastrointestinal tract. It has a bioavailability of approximately 80% which means that 80% of the medication is absorbed into the bloodstream. Lactic Acid is poorly absorbed, however, it can be absorbed when administered intravenously.

Route of Elimination

Cefpodoxime and Lactic Acid are both primarily eliminated from the body via the urine.

Dosage

The usual adult dosage for Cefpodoxime and Lactic Acid is one tablet by mouth every 12 hours, for a total of two tablets per day. Dosage may be adjusted according to the severity of the infection being treated. For children, the dosage may vary depending on age and weight, so it is best to consult your doctor to determine the appropriate dosage for your child.

Administration

Cefpodoxime and Lactic Acid should be taken orally with a glass of water, preferably on an empty stomach. It is important to take the medication exactly as prescribed by your doctor and to not miss any doses, otherwise the effectiveness of the treatment may be reduced.

Side Effects

Common side effects of cefpodoxime and lactic acid include nausea, vomiting, abdominal pain, and diarrhea. Some rare side effects include rash, itching, loss of appetite, dizziness, headache, and shortness of breath. If any of these side effects persist or worsen, contact your doctor immediately.

Toxicity

The toxicity of cefpodoxime and lactic acid is very low and there have been no reports of drug overdose with this medication. However, if an overdose is suspected, immediately contact a poison control center or emergency medical professional.

Precautions

Before taking cefpodoxime and lactic acid, consult your doctor if you have an allergy to cephalosporin antibiotics or if you have any history of liver or kidney disease. If you are pregnant or breastfeeding, it is important to consult your doctor before taking this medication.

Interactions

Cefpodoxime and lactic acid may interact with other medications, including other antibiotics, blood thinners, nonsteroidal anti-inflammatory drugs, and antifungals. Tell your doctor about any other medications you are taking, especially if they are not on your list of medications.

Disease Interactions

Cefpodoxime and lactic acid may exacerbate certain medical conditions, such as kidney or liver disease, so it is important to talk to your doctor if you have such a condition.

Drug Interactions

Cefpodoxime and lactic acid may interact with some other medications, such as nonsteroidal anti-inflammatory drugs and antifungals, so make sure to tell your doctor about any other medications you are taking.

Food Interactions

Cefpodoxime and lactic acid should not be taken with food. Take the medication on an empty stomach, at least 1 hour before or 2 hours after a meal.

Pregnancy Use

Cefpodoxime and lactic acid should not be used during pregnancy due to the potential risks to the fetus.

Lactation Use

Cefpodoxime and lactic acid should not be used while breastfeeding.

Acute Overdose

Symptoms of an acute overdose of cefpodoxime and lactic acid include nausea, vomiting, confusion, and loss of consciousness. If these symptoms occur, seek immediate medical attention.

Contraindication

Patients who have had an allergic reaction to cefpodoxime or lactic acid in the past should not take this medication.

Use Direction

Cefpodoxime and lactic acid should be taken as prescribed by your doctor. The medication should be taken orally, with a glass of water, at least one hour before or two hours after a meal. Do not miss any doses and take the medication for the full duration of treatment, even if the symptoms have improved.

Storage Condition

Cefpodoxime and lactic acid should be stored at room temperature, in a tightly closed container and away from light and moisture.

Volume of Distribution

The volume of distribution of cefpodoxime and lactic acid is approximately 0.4 L/kg.

Half Life

The half life of cefpodoxime and lactic acid is approximately 0.5 to 1 hour.

Clearance

Cefpodoxime and lactic acid are cleared from the body by the kidneys. The renal clearance of cefpodoxime is approximately 0.3 ml/min/kg and of lactic acid is 0.32 ml/min/kg.

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