Absolute

Absolute Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Absolute is a brand name. Its generic name is Olanzapine.

Absolute (Zyprexa)

Absolute is an atypical antipsychotic used to treat schizophrenia, bipolar disorder, and other mental illnesses. It is available in both generic and brand name forms. It works by blocking certain receptors in the brain that are responsible for psychotic symptoms.

Uses of Absolute

Absolute is used to treat schizophrenia, bipolar disorder, and other mental illnesses. It can also be used to help patients with severe depression, Tourette’s Syndrome, obsessive-compulsive disorder, and autism.

Mechanism of Action

Absolute works by blocking certain receptors in the brain that are responsible for psychotic symptoms. It increases the amount of serotonin and norepinephrine in the brain, which can help reduce anxiety and improve mood. Absolute can also block dopamine receptors in the brain, which can help reduce hallucinations or disorganized thinking.

How Long Does it Take to Work?

It typically takes a few weeks for olanzapine to start working. In some cases, it might take up to a few months for it to start working. The exact amount of time it takes to work varies for each individual.

Absorption

Absolute is rapidly and completely absorbed in the gastrointestinal tract. The peak plasma levels are reached in 2-4 hours.

Route of Elimination

The majority of olanzapine is excreted unchanged in the urine. A small fraction of olanzapine is metabolized to its active metabolite, 10-hydroxyolanzapine.

Dosage

The recommended starting dose of olanzapine is 5mg once a day. It can be increased up to 20mg per day. This should be done in increments of 5mg at a time. Your doctor may adjust your dose based on your symptoms and response to the drug. It is important to take olanzapine exactly as prescribed and not to take more than your doctor has ordered.

Administration

Absolute is taken orally, typically once a day with or without food. Swallow the pills whole, do not crush, chew, or break the tablets.

Side Effects

Common side effects of olanzapine may include dry mouth, drowsiness, constipation, weight gain, and increased heart rate. Other side effects may include nausea, vomiting, blurred vision, unusual thoughts or behavior, and trouble sleeping.

Toxicity

Absolute is considered a safe medication, but it may cause serious side effects. Symptoms of an overdose of olanzapine may include confusion, aggression, vomiting, and coma. If you suspect you have taken an overdose of olanzapine, contact emergency services immediately.

Precautions

Before taking olanzapine, tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. Also tell your doctor about all other medications you are taking, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Absolute may increase the risk of falls and other injuries.

Interaction

Absolute may interact with other medications, supplements, or herbal products. Tell your doctor about all medications you are taking before taking olanzapine. Your doctor may need to adjust your dose of olanzapine if you are taking any of the following medications: antibiotics, antifungals, antidepressants, blood thinners, diabetes medications, heart medications, seizure medications, HIV medication, and antipsychotics.

Drug Interactions

Absolute may interact with certain drugs. Drugs that may interact with olanzapine include: antifungals, antibiotics, antidepressants, cancer medications, blood thinners, HIV medications, seizure medications, antidiabetics, and heart medications.

Food Interactions

Absolute should be taken with food. Taking this medication with food may help to reduce stomach upset. Dairy products, high-fat meals, and antacids may reduce the absorption of olanzapine, so they should be avoided when taking this medication.

Pregnancy Use

Absolute is not recommended for use in pregnancy due to the potential for harm to the fetus. Speak to your doctor before taking olanzapine if you are pregnant or plan to become pregnant.

Lactation Use

The effects of olanzapine on breastfeeding infants is unknown. If you are breastfeeding, discuss with your doctor if olanzapine is right for you.

Acute Overdose

Symptoms of an overdose of olanzapine may include confusion, aggression, vomiting, and coma. If you suspect you have taken an overdose of olanzapine, contact emergency services immediately.

Contraindication

Absolute is contraindicated in patients with known hypersensitivity to the active ingredient or any other components of the medication.

Use Direction

Take olanzapine exactly as prescribed by your doctor. Swallow the pills whole, do not crush, chew, or break the tablets. Do not take more than the prescribed dose. Take olanzapine with or without food.

Storage Condition

Store olanzapine at room temperature away from moisture, heat, and light. Keep this medication out of reach of children and pets.

Volume of Distribution

Absolute has a volume of distribution of 9-11 liters/kg.

Half Life

The half-life of olanzapine is approximately 21-53 hours, meaning that it takes 21-53 hours for the concentration of olanzapine in the bloodstream to be reduced by 50%.

Clearance

Absolute has a clearance of 3-6 mL/min/kg.

Here you find in details version of Absolute

Some Frequently Asked Questions About Absolute

What is Absolute?

Absolute is an atypical antipsychotic drug commonly used to treat schizophrenia, bipolar disorder, and depression.

How does Absolute work?

Absolute works by blocking certain receptors in the brain that are associated with hallucinations and psychotic symptoms.

What are the side effects of Absolute?

Common side effects of Absolute include drowsiness, weight gain, dizziness, dry mouth, and constipation.

Can Absolute be used for anxiety?

Absolute is not approved for the treatment of anxiety but may be used off-label if other treatments have failed. It should be used with caution and monitored closely.

Can Absolute be used for depression?

Yes, Absolute is FDA approved for the treatment of depression when used in combination with another medication.

How long does it take for Absolute to work?

The effects of Absolute can vary depending on the individual. Generally, people may start to notice changes within a few weeks.

Can Absolute be taken at night?

Yes, Absolute can be taken at night. It is important to take it at the same time each day.

How is Absolute dispensed?

Absolute is available in tablets, disintegrating tablets, and oral solutions.

Is Absolute addictive?

No, Absolute is not considered to be addictive, but it can cause physical and psychological dependence. People should be monitored closely and tapered off the medication gradually.

What is Absolute used to treat?

Absolute is used to treat schizophrenia, bipolar disorder, and depression.

Can Absolute cause weight gain?

Yes, Absolute can cause weight gain. People should be monitored closely and encouraged to eat a healthy diet and exercise to mitigate these effects.

Does Absolute lower blood pressure?

Yes, Absolute can lower blood pressure. People should be monitored closely to ensure their blood pressure remains within a safe range.

Does Absolute cause drowsiness?

Yes, Absolute can cause drowsiness. People should not drive or operate heavy machinery until they know how the medication affects them.

Does Absolute interact with other medications?

Yes, Absolute can interact with other medications. People should tell their doctor about all medications they are taking before starting Absolute.

Can Absolute be used in children?

Absolute is approved for use in adults and not recommended for use in children. Speak to a doctor before giving Absolute to a child.

How should Absolute be stored?

Absolute should be stored at room temperature, away from light and moisture. It should be kept out of reach of children and pets.

What happens if I miss a dose of Absolute?

If you miss a dose of Absolute, take it as soon as possible. If it is close to the time of your next dose, skip the missed dose and continue with your normal schedule.

Does Absolute cause constipation?

Yes, Absolute can cause constipation. Drinking plenty of fluids and eating high-fiber foods may help to prevent this.

Can I drink alcohol while taking Absolute?

No, it is not recommended to drink alcohol while taking Absolute as it can increase the risk of side effects.

Is Absolute used for schizophrena?

Yes, Absolute is commonly used to treat schizophrenia.

Is Absolute used for bipolar disorder?

Yes, Absolute is also commonly used to treat bipolar disorder.

Does Absolute cause dry mouth?

Yes, Absolute can cause dry mouth. Chewing sugar-free gum or sucking on sugar-free candy may help to relieve this symptom.

Can I take Absolute while pregnant?

Absolute should only be used during pregnancy if the benefits outweigh the risks. Speak to your doctor for more information.

Is Absolute approved by the FDA?

Yes, Absolute is FDA approved for the treatment of schizophrenia, bipolar disorder, and depression when used in combination with another medication.

Are there any warnings associated with Absolute?

Yes, Absolute can increase the risk of suicidal thoughts and behavior, so people should be monitored closely for these effects.

How long should I take Absolute for?

The length of time Absolute should be taken for varies depending on the individual and should be discussed with a doctor.

Can Absolute cause changes in mood?

Yes, Absolute can cause changes in mood. People should be monitored closely for changes in mood or behavior.

Can Absolute cause blurred vision?

Yes, in some cases Absolute can cause blurred vision. People should report any changes in vision to their doctor.

Does Absolute take effect immediately?

No, Absolute does not take effect immediately. It may take several weeks for people to experience the full effects.

Can Absolute cause nausea?

Yes, Absolute can cause nausea. Eating small, frequent meals and avoiding foods that are high in fat may help to reduce the symptoms.

Are there any long-term side-effects of Absolute?

Yes, long-term use of Absolute can cause abnormal movements of the face and body such as tardive dyskinesia.

How can I reduce the side-effects of Absolute?

Eating a healthy diet, exercising regularly, and avoiding alcohol can help to reduce the side-effects of Absolute.

Does Absolute cause sleepiness?

Yes, Absolute can cause sleepiness. People should not drive or operate heavy machinery until they know how the medication affects them.

Does Absolute cause changes in appetite?

Yes, Absolute can cause changes in appetite. Eating small, frequent meals and avoiding foods that are high in fat may help to reduce the symptoms.

Can Absolute cause headaches?

Yes, Absolute can cause headaches. Taking over-the-counter pain relief medications may help to reduce the symptoms.

Can Absolute be used in the elderly?

Older adults may be more sensitive to the side effects of Absolute. It should be used with caution and monitored closely in the elderly.

Does Absolute cause restless legs?

Yes, Absolute can cause restless legs. Taking hot baths or massage may help to reduce the symptoms.

Can I stop taking Absolute suddenly?

No, Absolute should not be stopped suddenly as it can cause withdrawal symptoms such as nausea and dizziness. The dose should be gradually tapered off.

Can Absolute be used with other medications?

Yes, Absolute can be used with other medications. It is important to tell the doctor about all medications being taken before starting Absolute.

What are the risk factors of Absolute?

The risk factors of Absolute include the risk of weight gain and abnormal movements of the face and body.