Xefer
Xefer Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Xefer is a brand name. Its generic name is Ferric Carboxymaltose.
Xefer Introduction
Xefer is an injectable medication used to treat iron deficiency anemia. It is used when traditional oral iron medications have been ineffective or can't be taken.Uses for Xefer
Xefer is used to treat iron-deficiency anemia, a condition in which the body does not have enough healthy red blood cells due to a lack of iron. It works by supplementing the body with iron so that the body can make healthy red blood cells. It is especially useful in patients who cannot take oral iron products due to poor absorption or gastrointestinal intolerance.Mechanism of Action
Xefer works by supplementing the body with iron, which is needed to produce hemoglobin, the substance in the red blood cells that carries oxygen to other parts of the body. It works by binding iron to an amino acid chain that is easily absorbed into the bloodstream and transported to the cells that need it. This allows for maximum iron absorption in a short period of time.How Long Does It Take to Work?
Xefer generally begins to take effect within two to four hours of administration, and full therapeutic effects can be seen within 24 to 36 hours.Absorption and Route of Elimination
Xefer is absorbed by the intestines and enters circulation quickly. It is then eliminated via the kidneys in the urine.Dosage and Administration
Xefer is administered as an intravenous infusion over 30 minutes. The recommended dose is a single dose of 1000 mg administered intravenously over 30 minutes.Side Effects
Common side effects of Xefer include headache, nausea, vomiting, abdominal pain, and dizziness.Toxicity
Xefer has a low toxicity, and no serious reactions have been reported with its use.Precaution
Xefer should be used with caution in patients with known hypersensitivities to the product or its components.Interactions
Xefer may interact with certain medications that you may be taking. Therefore, it is important to inform your doctor of all medications you are taking, including vitamins, minerals and herbs before starting this medication.Disease Interactions
Xefer may interact with certain diseases, such as kidney disease, liver disease and heart disease. Therefore, it is important to inform your doctor of any diseases you have before taking this medication.Drug Interactions
Xefer may interact with certain medications, such as traditional oral iron therapies, antacids, and anti-inflammatories. Therefore, it is important to inform your doctor of all medications you are taking before starting on this medication.Food Interactions
Xefer should not be taken with foods that are high in vitamin C, as this may interfere with the absorption of the medication.Pregnancy Use
Xefer should be used with caution during pregnancy, as it may affect fetal growth and development. Therefore, it is recommended to discuss the risks and benefits of taking this medication with your doctor before using it during pregnancy.Lactation Use
Xefer is excreted in breast milk, and should be used with caution while breastfeeding.Acute Overdose
An acute overdose of Xefer is not likely to cause serious harm. However, it is important to seek medical attention if an overdose is suspected.Contraindication
Xefer is contraindicated in patients with known hypersensitivity to the product or any of its components. It is also contraindicated in patients with a history of iron overload, or conditions associated with iron overload, such as hemochromatosis.Use Direction
FerricCarboxymaltose should be administered as an intravenous infusion over 30 minutes. The recommended dose is 1000 mg administered intravenously over 30 minutes.Storage Conditions
Xefer should be stored at room temperature, between 59°F and 86°F (15°C and 30°C). It should be stored away from light and moisture.Volume of Distribution
The volume of distribution of Xefer is estimated to be 4.05 L/kg.Half Life
The half-life of Xefer is approximately 5 hours.Clearance
The clearance of Xefer is estimated to be 1.25 L/h/kg.Here you find in details version of Xefer
Some Frequently Asked Questions About Xefer
What is Xefer?
Ferric carboxymaltose is a sterile, injectable, iron replacement product used to treat iron deficiency anemia (IDA) in adults. It is an iron complex consisting of a labile, non-esterified, low-molecular-weight fraction of ferric hydroxide with a carboxymaltose molecule. It is the only injectable iron replacement product available in the United States.
What are the uses of Xefer?
Ferric carboxymaltose is used to treat iron deficiency anemia, which is a condition in which the body does not have enough healthy red blood cells because of an iron-deficiency. This medicine works by giving the body needed iron to create new healthy red blood cells.
Who produces Xefer?
Ferric carboxymaltose is produced by laboratories such as Alvogen Pharma, Inc. and Baxter International Inc. in the United States.
Is a prescription needed to obtain Xefer?
Yes, a prescription is needed to obtain Xefer.
Is Xefer a generic drug?
No, Xefer is not a generic drug.
What should I tell my doctor before receiving Xefer?
You should tell your doctor if you have a history of liver or kidney disease, any allergies, or if you are pregnant or breastfeeding.
What form does Xefer come in?
Xefer comes in a single-use vial or prefilled syringe and is administered as an intravenous (IV) infusion.
How often is Xefer administered?
Xefer is usually administered as an intravenous (IV) infusion once a month.
How long does Xefer take to work?
Xefer usually begins to work within a few days after receiving the first infusion. The full effect may take up to a month.
What are the possible side effects of Xefer?
Side effects can occur with Xefer and may include nausea, vomiting, diarrhea, dizziness, headache, skin rash, and an irregular heartbeat.
Can Xefer be used with other medications?
You should always tell your doctor and pharmacist about all medications you are taking, including prescription, non-prescription, herbal, and nutritional supplements, before starting with Xefer. Certain medications may interact with Xefer and affect how it works, or increase the risk of side effects.
What should I do if I forget to take a dose of Xefer?
If you forget to take a dose of Xefer, contact your doctor or nurse immediately. You should not take a double dose to make up for the missed dose.
Does Xefer require special storage conditions?
Yes, Xefer should be stored at temperatures between 2°C to 25°C (35°F to 77°F). It should not be frozen, and should not be exposed to light.
What should I do if I experience an allergic reaction to Xefer?
If you experience an allergic reaction to Xefer such as skin rash, itching or hives, swelling of the face, lips, or tongue, breathing problems, or dizziness, stop using the medication and contact your doctor immediately.
How long does Xefer stay in the body?
The half-life of Xefer is about 3 days, but it can vary based on individual factors such as age, weight, and kidney and liver function.
What should I do if I have an overdose of Xefer?
If you think you have taken an overdose of Xefer, seek medical attention immediately. Symptoms of an overdose include increased heart rate, shortness of breath, and unusual fatigue or dizziness.
Can I take Xefer if I’m pregnant or breastfeeding?
You should not take Xefer if you are pregnant or breastfeeding unless your doctor has specifically recommended it. Discuss the potential risks and benefits with your doctor.
Is Xefer covered by insurance?
It depends on the individual’s insurance plan. Contact your insurance provider to confirm coverage.
Is there a generic version of Xefer available?
No, there is not a generic version of Xefer available.
Can Xefer be taken with food or alcohol?
Xefer should be taken as directed by your doctor. Ask your doctor if it is safe to take with food or alcohol.
What is the recommended dosage of Xefer?
The recommended dose of Xefer is 15 to 1000 mg (based on body weight) administered as an intravenous (IV) infusion over at least 15 minutes, not more than once a month.
How should Xefer be administered?
Xefer should be administered as an IV infusion over at least 15 minutes. Your healthcare provider will determine the best dosage and infusion rate for you.
Is Xefer safe for children?
Xefer is not approved for use in children; however, it is possible that it could be prescribed for a child in certain circumstances. Speak with your child's doctor to determine if Xefer is right for your child.
Can Xefer be taken with other iron supplements?
No, Xefer should not be taken with other iron supplements such as oral iron tablets or iron drops. Taking other iron supplements with Xefer can lead to toxicity.
What should I do if I experience problems with the device used to administer Xefer?
If you experience any problems with the device used to administer Xefer, contact your healthcare provider immediately.
What is the most common side effect of Xefer?
The most common side effect of Xefer is nausea.
Is Xefer considered a safe medication?
Xefer is considered safe when used as directed. However, some people may be more sensitive to the effects of Xefer and may experience side effects such as nausea, vomiting, headache, and skin rash.
How long does a Xefer infusion take?
The infusion of Xefer usually takes 15 minutes or less to complete.
What is the difference between Xefer and other iron replacement products?
Xefer is an injectable iron replacement product while other iron replacement products are taken orally. Xefer is more effective in restoring hemoglobin levels in people with iron deficiency anemia than traditional oral supplements.
Can Xefer be used to treat anemia not related to iron deficiency?
No, Xefer is not recommended for use in people with anemia not related to iron deficiency.
Is Xefer safe for long-term use?
Xefer is generally safe for long-term use, but should only be used under the supervision of a healthcare professional. Speak to your doctor if you have any concerns.
What are the potential benefits of Xefer?
Xefer is generally used to treat iron deficiency anemia and can help to improve energy levels, restore red blood cell production, and improve muscle and organ function.
Is Xefer available over-the-counter?
No, Xefer is not available over-the-counter; it is a prescription only medicine.
Does Xefer have any drug interactions?
Certain medications may interact with Xefer and affect how it works, or increase the risk of side effects. It is important to tell your doctor and pharmacist about all medications you are taking before starting with Xefer.
Who should not take Xefer?
Xefer is not recommended for people with a history of liver or kidney disease, any allergies, or those who are pregnant or breastfeeding unless specifically recommended by a doctor. Speak to your doctor if you have any concerns.
Can Xefer interact with other medications?
Yes, certain medications can interact with Xefer and affect how it works, or increase the risk of side effects. It is important to tell your doctor and pharmacist about all medications you are taking, including prescription, non-prescription, herbal, and nutritional supplements, before starting with Xefer.
What are the signs of an allergic reaction to Xefer?
Signs of an allergic reaction to Xefer can include skin rash, itching or hives, swelling of the face, lips, or tongue, breathing problems, or dizziness. If you experience any of these signs, stop using Xefer and contact your doctor or healthcare provider immediately.