Xalcom
Xalcom Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Xalcom is a brand name. Its generic name is Latanoprost + Timolol.
Introduction
Xalcom is a combination of two medications—latanoprost and timolol, which are used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It is the only fixed combination of two active ingredients approved by the FDA for treating ocular Hypertension and glaucoma.Uses
Xalcom is used to reduce intraocular pressure (IOP) in patients with open angle glaucoma or ocular hypertension who are intolerant of other intraocular pressure lowering medications.Mechanism of Action
Latanoprost works to reduce intraocular pressure by increasing the outflow of aqueous humor from the eye into nearby tissues, thus decreasing fluid pressure behind the eye. Timolol works to reduce the amount of fluid produced by the ciliary body, thus reducing intraocular pressure.How Long Does It Take to Work?
Xalcom usually starts to work within 12 hours of administration. It is most effective within 24 hours after administration. If, after several weeks, it has not been effective in reducing intraocular pressure, it is advisable to consult with your doctor.Absorption
Xalcom is readily absorbed through the cornea of the eye into the systemic circulation. It is approximately 95% bound to plasma proteins.Route of Elimuation
Xalcom is eliminated by hepatic metabolism. The metabolites are excreted in the urine and feces.Dosage
Xalcom should be administered once daily, preferably at the same time each day. The usual recommended dose is one drop in the affected eye(s) once daily.Administration
Xalcom is for ophthalmic use only. To administer, gently pull down the lower eyelid and place the drops on the inner corner of the eye. Close the eye and apply pressure for 1-2 minutes.Side Effects
The most common side effects associated with Xalcom use are eye burning, stinging, and irritation; eyelash growth and thickening; redness; itching or dryness of the eyes; blurred vision; and increased sensitivity to light.Toxicity
There is no reported case of acute toxicity associated with Xalcom use.Precautions
Xalcom should not be used in patients with a known history of hypersensitivity to either of the active ingredients.Interactions
Latanoprost + Timothy may interact with other medications, including cyclosporine, systemic beta blockers, calcium channel blockers, and CNS depressants.Disease Interactions
Xalcom should not be used in patients with active or suspected intraocular inflammation or in those with acute angle-closure glaucoma.Drug Interactions
Xalcom may interact with other medications, including cyclosporine, systemic beta blockers, calcium channel blockers, and CNS depressants.Food Interactions
There are no known food or beverage interactions with Xalcom.Pregnancy Use
Xalcom should not be used during pregnancy unless clearly necessary. If used during pregnancy, Xalcom should be used with caution and only if the potential benefit justifies the potential risk to the fetus.Lactation Use
It is not known whether Xalcom is excreted in breast milk. Caution should be exercised when administering Xalcom to nursing women.Acute Overdose
Acute overdose with Xalcom is not expected to cause life-threatening symptoms. Symptoms of overdose may include increased eye irritation, eye redness, difficulty focusing, and sensitivity to light. Contact a healthcare professional immediately if an overdose is suspected.Contraindications
Xalcom is contraindicated in patients with active or suspected intraocular inflammation, as well as those with acute angle-closure glaucoma. It is also contraindicated in patients with known hypersensitivity to either of the active ingredients.Use Direction
Xalcom should be administered as a single dose of one drop in the affected eye(s) once daily, preferably at the same time each day. The drops should be gently pulled down on the lower eyelid and placed on the inner corner of the eye. Close the eye and apply pressure for 1-2 minutes.Storage Condition
Xalcom should be stored at a temperature between 2°C and 25°C. It should be kept away from heat, light, and moisture.Volume of Distribution
The volume of distribution of Xalcom is approximately 2 L/kg.Half Life
The half life of Xalcom is approximately 11 hours.Clearance
The clearance of Xalcom is approximately 0.48 L/hr/kg.Here you find in details version of Xalcom
Some Frequently Asked Questions About Xalcom
What is Xalcom?
Xalcom is a prescription eye drop used to lower pressure inside the eye and reduce the risk of glaucoma. It is a combination of two different types of medications, latanoprost and timolol, which work together to lower the pressure inside the eye.
How does Xalcom work?
Xalcom works by reducing the amount of fluid produced in the eye and increasing the outflow of existing fluid. This helps to reduce the pressure inside the eye and reducing the risk of glaucoma.
What is Xalcom used to treat?
Xalcom is used to treat glaucoma and ocular hypertension. It is used to reduce pain and pressure inside the eye caused by problems with the drainage of the eye fluid. It can also be used to treat other eye conditions such as corneal endothelial dysfunction.
What are the side effects of Xalcom?
The most common side effects of Xalcom are red or watery eyes, stinging or burning, irritation, and blurred vision. Other more serious side effects include change in eye color, eyelid discoloration, and sensitivity to light. If you experience any of these side effects, or any other side effects, contact your doctor right away.
What should I do if I miss taking Xalcom?
If you miss a dose of Xalcom, you should take it as soon as you can. However, if you are close to the time for your next dose, wait until then and take your regular dose. Do not take a double dose to make up for the missed one. If you have questions about how to take your medications, contact your doctor.
Are there any drug interactions with Xalcom?
Yes, there are some drug interactions with Xalcom. It is important to tell your doctor and pharmacist about all the medications you are taking, especially other eye drops and other medications. It is also important to tell them about herbal supplements and any over the counter medications you are taking. Some drug interactions with Xalcom can cause serious side effects that need to be treated by a doctor.
Who should not take Xalcom?
Xalcom should not be taken if you are allergic to latanoprost, timolol, other eye drops, or any of the ingredients in Xalcom. It should also not be taken if you have any active eye or eyelid infections, corneal ulcers, or nut allergies. Tell your doctor if you have a history of any other eye problems or conditions, asthma, heart or blood pressure problems, kidney or liver disease, or any other serious medical conditions.
What forms does Xalcom come in?
Xalcom comes in a solution form that is administered as an eye drop. It is usually given once per day in the evening or at bedtime. Always follow your doctor's instructions when using this medication.
How long do I need to take Xalcom?
Xalcom is usually used on a long-term basis to control eye pressure. It is important to continue taking Xalcom even if you do not have any symptoms or if your symptoms improve. If your doctor suggests that you stop taking Xalcom, wean yourself off it in a slow and gradual manner.
Is Xalcom safe in pregnancy or while breastfeeding?
Xalcom is likely safe to use in pregnancy and when breastfeeding. However, it is always best to speak to your doctor before taking any medication or supplement. If you are pregnant or breastfeeding, tell your doctor before taking this medication.
How do I store Xalcom?
You should store your Xalcom at room temperature, away from direct sunlight and heat. Keep the bottle in its original container and do not touch the tip of the bottle with your fingers. Always wash your hands before and after touching the bottle. If the bottle becomes stained or discolored, empty it and rinse it with warm water before using it. Keep Xalcom out of reach of children and pets.
How long does Xalcom stay in your system?
Xalcom may stay in your system for up to 24 hours after each dose. However, it is important to follow your doctor's instructions for taking this medication.
Does Xalcom cause any vision problems?
Xalcom may cause some temporary vision problems. These usually go away after a few days, but if they do not, contact your doctor. Other potential vision problems associated with Xalcom include blurred vision, visual disturbances, and eye pain.
Does Xalcom cause any dry eyes?
Xalcom can cause dry eyes. If you experience dry eyes while taking this medication, contact your doctor. Dry eyes may be a sign that your body is not able to tolerate the medication and you may need to seek an alternative treatment.
Will Xalcom make my eyes more sensitive to light?
Yes, Xalcom may cause your eyes to be more sensitive to light. If you experience sensitivity to light while taking this medication, wear sunglasses and avoid direct bright light. If you have any questions about your eye sensitivity, contact your doctor.
Can Xalcom cause my eyes to change color?
Yes, Xalcom may cause the color of your eyes to change. If you experience a change in eye color while taking this medication, contact your doctor right away. Changes in eye color may be a sign of an underlying condition that requires medical attention.
Is there a generic version of Xalcom?
Yes, there is a generic version of Xalcom. It is a combination of two generic medications, latanoprost and timolol. Talk to your doctor or pharmacist to see if generic versions of Xalcom are available and if they are appropriate for you.
Can I wear contact lenses while taking Xalcom?
Yes, you can wear contact lenses while taking Xalcom. However, it is important to follow your eye care professional’s instructions when putting in and taking out your lenses. It may also be helpful to put in your contacts before administering the eye drop.
Can I wear makeup while taking Xalcom?
Yes, you can wear makeup while taking Xalcom. However, it is important to wait at least 15 minutes after applying the medication before putting on your makeup. This gives the drug time to be absorbed and to work its effect.
Does Xalcom interact with other medications?
Yes, Xalcom may interact with other medications. It is important to tell your doctor and pharmacist about all the medications you are taking, especially other eye drops and other medications. It is also important to tell them about herbal supplements and any over-the-counter medications you are taking. Some drug interactions with Xalcom can cause serious side effects that need to be treated by a doctor.
Can Xalcom be used to treat other eye problems?
Yes, Xalcom can be used to treat other eye problems. However, it is important to consult your doctor first to make sure that it is the right treatment for your condition. Xalcom is only approved to treat glaucoma and ocular hypertension.
Do I need to avoid any activities while taking Xalcom?
Yes, you should avoid activities that require clear vision, such as driving, while taking Xalcom. The medication may cause blurred vision, which can make it more difficult to drive safely. Give yourself time to get used to the medication before engaging in activities that require clear vision.
What happens if I stop taking Xalcom?
It is important to continue taking Xalcom even if you do not have any symptoms or if your symptoms improve. If your doctor suggests that you stop taking Xalcom, wean yourself off it in a slow and gradual manner. Stopping Xalcom abruptly may cause the eye pressure to increase and may also cause damage to the optic nerve.
Will I need to have regular check-ups while taking Xalcom?
Yes, it is important to have regular check-ups while taking Xalcom. Your doctor will monitor your eye pressure and check for any side effects or signs of damage to the optic nerve. Make sure to keep all of your appointments and follow your doctor's instructions for taking this medication.
What should I do if I think my Xalcom is not working?
If you think your Xalcom is not working, talk to your doctor. They may want to change your dose or try another medication. It is important to keep all of your appointments so that your doctor can accurately monitor your eye pressure and check for any side effects or signs of damage to the optic nerve.
What should I do if my eyes become red or watery while using Xalcom?
Red or watery eyes are common side effects of Xalcom. If you experience these side effects, try to reduce the amount of Xalcom you are using. If the symptoms do not go away after reducing your dose, contact your doctor.
Can Xalcom cause dizziness?
Yes, Xalcom can cause dizziness. If you experience dizziness while taking this medication, wait until you feel comfortable moving around before engaging in activities that require clear vision. If the dizziness persists, contact your doctor.
Does Xalcom cause an increase in appetite?
Xalcom is not known to cause an increase in appetite. If you experience an increase in appetite while taking this medication, contact your doctor. This could be a sign of an underlying condition that may need to be treated.
Can I take Xalcom with allergy medications?
Yes, you can take Xalcom with allergy medications. However, it is important to talk to your doctor about the potential side effects and interactions with other medications. Be sure to tell your doctor about all the medications and supplements you are taking.
Does Xalcom cause nausea?
Xalcom is not known to cause nausea. However, if you experience nausea or other side effects while taking this medication, contact your doctor. Your doctor may suggest an alternative medication or a lower dose of the medication.
Does Xalcom cause headaches?
Xalcom is not known to cause headaches. If you experience headaches while taking this medication, contact your doctor. This could be a sign of an underlying condition that may need to be treated.
Can Xalcom cause eye irritation?
Yes, Xalcom may cause eye irritation. If you experience eye irritation while taking this medication, try to reduce the amount of Xalcom