Water for injection
Water for injection Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Water for injection is a brand name. Its generic name is Water for injection.
What is Water for Injection?
Water for injection (WFI) is a sterile, distilled, depyrogenated water for use as an excipient in pharmaceutical parenteral and other sterile dosage forms. It is not intended for direct intravenous (IV) use, but for compounding sterile preparations when further manipulations such as filtration, dilution or addition of a drug are required.Uses of Water for Injection
Water for injection is commonly used in medical and laboratory settings, particularly within the pharmaceutical industry and for producing sterile pharmaceutical products. Its primary uses include:- Creating intravenous mixtures
- Making oral solutions
- Preparing stock solutions for laboratory use
- Producing antibiotic pharmaceutical products
- Producing sterile liquid dosage forms
- Creating progesterone injections
- Making monoclonal antibodies
Mechanism of Action
Water for injection does not contain any active compounds; thus, it does not have a specific mechanism of action. It is used as an excipient or carrier in the manufacture of parenteral and other sterile dosage forms. Its importance lies in its ability to:- Dissolve high solubility drugs
- Inhibit the growth of contaminate microorganisms
- Provide an inert medium for pharmaceutical products
How Long Does It Take to Work?
Water for injection does not contain any active agents and thus does not have an active effect. The product is used as a carrier for other active agents or as a medium for mixing and dissolving other parenteral drugs.Absorption
Water for injection does not contain any active pharmaceutical components; thus, it has no absorption properties. It is used as a medium for delivering other drugs to the body which are absorbed when administered.Route of Elimination
Water for injection is eliminated from the body in the same manner as any other fluid ingested. Generally, it is removed from the body through the urinary and gastrointestinal tracts.Dosage
Water for injection does not contain any active agents; thus, it does not have a specific dosage. The amount of WFI used in a formulation is dependent on the pharmaceutical product being produced and its required components.Administration
Water for injection should not be taken internally, injected intravenously or used as a sterile irrigation solution for surgery. It is recommended to use the product within 24 hours of opening and according to the manufacturer’s guidelines.Side Effects
Water for injection does not contain any active components; thus, it is not associated with any significant side effects.Toxicity
Water for injection is not toxic and does not contain any active ingredients. Thus, it is not associated with any systemic toxicity.Precautions
Despite its safety profile, there are some precautions to keep in mind when using water for injection:- Do not use pre-filled syringes of water for injection, unless approved and recommended by a doctor or pharmacist.
- Make sure that the product is labelled correctly and the container is sealed.
- Store the product away from direct sunlight and heat. Do not freeze.
- Do not use if the solution is cloudy, discoloured, or contains particulate matter.
Interactions
Water for injection does not contain any active components, and thus is not expected to interact with any medications or drugs.Disease Interactions
Water for injection does not contain any active components and thus is not associated with any disease interactions.Drug Interactions
Water for injection does not contain any active components and thus is not expected to interact with any medications or drugs.Food Interactions
Water for injection does not contain any active components and thus is not likely to interact with any foods.Pregnancy Use
Water for injection does not contain any active components and thus is not associated with any significant adverse effects when used during pregnancy. As with any medication or excipient, it is recommended to consult a doctor before use.Lactation Use
Water for injection does not contain any active components and is generally regarded as safe for use during lactation. It is recommended to collect samples of breast milk prior to use to ensure no unexpected adverse effects have occurred.Acute Overdose
Water for injection does not contain any active components, and an overdose is unlikely to cause any serious adverse effects. Symptoms of an overdose may include nausea, vomiting, and diarrhoea. If an overdose occurs, it is recommended to seek medical advice.Contraindication
Water for injection does not contain any active components, and thus is not associated with any contraindications.Use Direction
Water for injection should only be used for compounding and production of sterile solutions and pharmaceutical products. It should not be used for intravenous or irrigation solutions, taken internally, or used for any purpose other than that intended.Storage Condition
Water for injection should always be stored in a cool, dry place away from direct heat or sunlight. It should not be frozen and should always be used according to the manufacturer’s instructions.Volume of Distribution
Water for injection does not contain any active components and thus does not have an associated volume of distribution.Half Life
Water for injection does not contain any active components, and thus does not have an associated half life.Clearance
Water for injection does not contain any active components and thus is not associated with any clearance parameters.Here you find in details version of Water for injection