Valfect H

Valfect H Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Valfect H is a brand name. Its generic name is Valsartan + Hydrochlorothiazide.

Introduction

Valfect H is a combination drug that is used to treat hypertension (high blood pressure). It is used when alone treatment with either drug has not been effective or if the patient's doctor decides that a combination drug is best for them.

Uses

Valfect H is an antihypertensive medicine, used for the treatment of essential hypertension. The drug is also used for the treatment of edema (fluid retention).

Mechanism of action

Valsartan is an angiotensin receptor blocker (ARB) and works by blocking the effects of angiotensin II. Angiotensin II is a hormone that narrows blood vessels and increases blood pressure. By blocking the action of angiotensin II, Valsartan causes the blood vessels to relax which decreases blood pressure and improves blood flow. Hydrochlorothiazide is a diuretic (water pill) and works by increasing the amount of water and sodium that is excreted in the urine. This increased urine output decreases the amount of water in the body, which reduces blood volume, which causes a decrease in blood pressure.

How long does it take to work?

Although individual patient response will vary, it usually takes 2-4 weeks for Valfect H to reach a therapeutic effect on blood pressure.

Absorption

No information available.

Route of elimination

Valfect H is primarily eliminated through the kidneys, with approximately 66% of its metabolites excreted via the urine.

Dosage

Valfect H is available in tablets containing 80 mg of valsartan and 12.5 mg of hydrochlorothiazide, and 160 mg of valsartan and 12.5 mg of hydrochlorothiazide. Patients should take Valfect H exactly as their doctor has prescribed.

Administration

Valfect H should be taken orally once daily with or without food.

Side effects

Common side effects of Valfect H include dizziness, lightheadedness, headache, tiredness, nausea, diarrhea, and rash. These side effects are usually mild and will go away with time. In rare cases, more serious side effects can occur, such as fainting, severe low blood pressure, and difficulty breathing. If these side effects occur, the patient should seek medical attention immediately.

Toxicity

Valfect H is not typically toxic if taken as prescribed by the doctor. However, if the drug is taken in large doses, it can lead to serious and potentially life-threatening conditions, including low blood pressure, electrolyte imbalances, and kidney damage.

Precautions

Patients on Valfect H should not stop taking the drug without consulting with their doctor. The drug can cause a sudden worsening of blood pressure if stopped abruptly.

Interactions

Valfect H can interact with other medicines and supplements, so patients should always let their doctor know of any other medicines or supplements they are taking.

Disease Interactions

Patients with kidney disease, liver disease, heart disease, or diabetes should discuss with their doctor whether Valfect H is safe for them to take.

Drug Interactions

Valfect H can interact with other drugs and should be used with caution in patients taking ACE inhibitors, ARBs, lithium, probenecid, and nonsteroidal anti-inflammatory drugs (NSAIDs).

Food Interactions

No information available.

Pregnancy Use

Valfect H should not be taken by pregnant women. This drug can cause birth defects and harm an unborn baby.

Lactation Use

Valfect H is excreted in breast milk and should not be used by nursing mothers.

Acute Overdose

Signs of an acute overdose may include low blood pressure, difficulty breathing, dizziness, and fainting. If an overdose is suspected, seek medical help immediately.

Contraindication

Valfect H should not be used by patients who are hypersensitive to either valsartan or hydrochlorothiazide.

Use Direction

Valfect H should be taken exactly as prescribed by the doctor. Patients should not adjust their dose or cease taking the drug without consulting with their doctor.

Storage Condition

Valfect H should be stored at room temperature, away from moisture and heat.

Volume of Distribution

No information available.

Half Life

Valsartan has a half-life of approximately 6 hours, with a range of 2.3 to 8 hours. Hydrochlorothiazide has a half-life of approximately 6.3 hours, with a range of 1.5 to 25.6 hours.

Clearance

No information available.

Here you find in details version of Valfect H

Some Frequently Asked Questions About Valfect H

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What is Valfect H?

Valfect H is a combination medication, containing the drugs valsartan and hydrochlorothiazide. Valsartan is an angiotensin-receptor blocker, which works to relax the muscles of the blood vessels. Hydrochlorothiazide is a type of diuretic, which helps to reduce the amount of fluid in the body.

What is the purpose of taking Valfect H?

Valfect H is used to treat high blood pressure. This combination medication works to relax the muscles of the blood vessels and reduce the amount of fluid in the body to help lower blood pressure.

How do I take Valfect H?

Valfect H should be taken exactly as prescribed by your doctor. Generally, the medication is taken once a day. It is important to take the medication at approximately the same time each day and to not miss any doses.

What are the possible side effects of taking Valfect H?

Common side effects of taking Valfect H include headache, tired feeling, weakness, drowsiness, nausea, vomiting, upset stomach, increased urination, muscle cramps, itching, joint pain, and blurred vision. If these side effects become severe, contact your doctor.

Who should not take Valfect H?

Valfect H is not suitable for everyone. People who are allergic to either valsartan or hydrochlorothiazide should not take Valfect H. It is important to inform your doctor about any medications you are currently taking, as some medications can interact negatively with Valfect H.

Is Valfect H safe during pregnancy?

There is not enough research to determine whether Valfect H is safe during pregnancy. It is important to speak with your doctor before taking Valfect H if you are pregnant or trying to become pregnant.

What should I do if I miss a dose of Valfect H?

If you miss a dose of Valfect H, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose as scheduled. It is important not to double the dose.

Can I take Valfect H with other medications?

It is important to speak with your doctor before taking Valfect H with other medications, as some medications can interact negatively with Valfect H. These include other blood pressure medications, NSAIDs, antivirals, antifungals, lithium, and digoxin.

Can I drink alcohol while taking Valfect H?

Drinking alcohol while taking Valfect H is not recommended, as alcohol can increase the risk of side effects such as lightheadedness and fainting. It is important to consult with your doctor before drinking alcohol while taking Valfect H.

When should I stop taking Valfect H?

Valfect H should generally be taken as prescribed by your doctor. If you experience severe side effects, it is important to contact your doctor, who may advise to stop taking the medication. You should never stop taking Valfect H without first speaking to your doctor.

What should I do if I experience an allergic reaction while taking Valfect H?

If you experience an allergic reaction while taking Valfect H, stop taking the medication right away and seek medical help. Symptoms of an allergic reaction include hives, difficulty breathing, and swelling of the face, tongue, and throat.

What should I do if I experience chest pain while taking Valfect H?

If you experience chest pain while taking Valfect H, stop taking the medication right away and seek medical help. Chest pain is a potential side effect of taking Valfect H.

Can I take Valfect H to treat a cough?

No, Valfect H should not be taken to treat a cough. Valfect H is a medication used to treat high blood pressure, not a cough.

Can children take Valfect H?

No, Valfect H is not suitable for children. Valfect H is only approved for use in adults.

Can I take Valfect H if I have diabetes?

Yes, you can take Valfect H if you have diabetes. However, it is important to let your doctor know that you have diabetes, as some medications can interact negatively with Valfect H.

What happens if I take an overdose of Valfect H?

If you take an overdose of Valfect H, it is important to seek medical help right away. Symptoms of an overdose can include nausea, vomiting, dizziness, and fainting.

What should I do if I forget to take my dose of Valfect H?

If you forget to take a dose of Valfect H, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose as scheduled. It is important not to double the dose.

Can I take Valfect H if I have a kidney condition?

Yes, you can take Valfect H if you have a kidney condition. However, it is important to consult with your doctor before taking the medication. Your doctor may need to adjust your dose or monitor your kidney condition more closely.

Can Valfect H cause weight gain?

Valfect H has not been proven to cause weight gain. However, if you are experiencing abnormal weight gain while taking Valfect H, it is important to consult with your doctor.

Can Valfect H cause dry mouth?

Yes, Valfect H can cause dry mouth. If you experience dry mouth while taking Valfect H, it is important to speak with your doctor.

Can I take Valfect H if I am breastfeeding?

No, Valfect H is not suitable for breastfeeding women. It is important to consult with your doctor if you are breastfeeding before taking Valfect H.

What should I do if I experience dizziness while taking Valfect H?

If you experience dizziness while taking Valfect H, it is important to speak with your doctor. You may need to have your dose adjusted or you may need to stop taking the medication.

Are there any dietary restrictions while taking Valfect H?

No, there are no dietary restrictions while taking Valfect H. However, it is important to speak with your doctor before making any major changes to your diet, as some dietary factors may affect the effectiveness of the medication.

What should I do if I experience diarrhea while taking Valfect H?

If you experience diarrhea while taking Valfect H, it is important to contact your doctor. Diarrhea is a potential side effect of taking this medication.

What should I do if I experience joint pain while taking Valfect H?

If you experience joint pain while taking Valfect H, it is important to contact your doctor. Joint pain is a potential side effect of taking this medication.

Can I take Valfect H while pregnant?

There is not enough research to determine whether Valfect H is safe during pregnancy. It is important to speak with your doctor before taking Valfect H if you are pregnant or trying to become pregnant.

How quickly does Valfect H work?

Valfect H begins working right away. However, it may take several weeks for the full effects of the medication to be reached.

Can Valfect H cause hair loss?

Valfect H has not been proven to cause hair loss. However, if you are experiencing abnormal hair loss while taking Valfect H, it is important to consult with your doctor.

Is it safe to take Valfect H with other blood pressure medications?

No, it is not safe to take Valfect H with other blood pressure medications. It is important to speak with your doctor before taking Valfect H with other medications, as some medications can interact negatively with Valfect H.

Can I take Valfect H if I have liver disease?

Yes, you can take Valfect H if you have liver disease. However, it is important to consult with your doctor before taking the medication. Your doctor may need to adjust your dose or monitor your liver condition more closely.

What should I do if my blood pressure does not improve while taking Valfect H?

If your blood pressure does not improve while taking Valfect H, it is important to contact your doctor. Your doctor may need to adjust your dose or try a different medication to help lower your blood pressure.

Does Valfect H interact with any other medications?

Yes, Valfect H can interact with other medications. It is important to speak with your doctor before taking Valfect H with other medications, as some medications can interact negatively with Valfect H. These include other blood pressure medications, NSAIDs, antivirals, antifungals, lithium, and digoxin.

Can Valfect H be used to treat heart failure?

No, Valfect H should not be used to treat heart failure. Valfect H is a medication used to treat high blood pressure, not heart failure.

Does Valfect H cause fatigue?

Yes, Valfect H can cause fatigue. If you experience fatigue while taking Valfect H, it is important to contact your doctor. Your doctor may need to adjust your dose or switch you to a different medication.

Does Valfect H cause insomnia?