Timeth
Timeth Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Timeth is a brand name. Its generic name is Tiemonium Methylsulphate.
Introduction
Timeth (TM), also known as Ragwitek or Merck Brand name Tezepelumab, is a biological drug used to treat moderate to severe atopic dermatitis. It belongs to a class of medications known as monoclonal antibodies. It works by blocking chemicals that are involved in inflammation.Uses
Timeth is typically used to treat moderate to severe atopic dermatitis (eczema) in both adults and children aged 6 years and older. It has also recently been approved for the treatment of certain forms of chronic obstructive pulmonary disease (COPD) in adults.Mechanism of Action
Timeth works by blocking a protein called thymic stromal lymphopoietin (TSLP), which is involved in the inflammation associated with atopic dermatitis. By blocking TSLP, the inflammation in the skin can be reduced, resulting in fewer and less severe flare-ups of atopic dermatitis.How Long Does it Take to Work?
The effects of Timeth can be seen as soon as 1 week after starting treatment, although it may take up to 8 weeks to see full results.Absorption
Timeth is administered as an injection under the skin (subcutaneously). It is completely absorbed through this route, with peak concentrations occurring approximately 1 week after injection.Route of Elimination
Timeth is eliminated through the kidneys, primarily as its active metabolite, desethyl tiemonium, which is excreted in urine.Dosage
The recommended dosage of Timeth is 200 mg given as an injection beneath the skin (subcutaneously) every 4 weeks.Administration
Timeth should be administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. Individuals using the medication should be monitored closely for potential side effects.Side Effects
Common side effects of Timeth may include:- Redness, pain, or swelling at the injection site
- Headache
- Joint pain
- Nausea
- Diarrhea
- Fever
- Fatigue
Toxicity
There are no reports of toxicity associated with Timeth use, however it can cause serious side effects in certain individuals.Precautions
- Timeth should not be used by individuals with known hypersensitivity to the drug or any of its components.
- Patients should be under close medical supervision when being treated with this drug.
- Patients should also be monitored for signs and symptoms of infection, such as fever, chills, cough, sore throat, or other signs of infection, while being treated with this drug.
Interactions
Timeth may interact with other medications, herbs, or supplements that may also affect the skin, including retinoids, calcitriol, and tacrolimus.Disease Interactions
Timeth should be used with caution in patients with severe kidney disease, cirrhosis of the liver, or HIV/AIDS.Drug Interactions
Timeth may interact with certain drugs, including antiepileptic drugs, immunosuppressants, and other drugs that are used to treat atopic dermatitis. Patients should consult with their healthcare provider before taking Timeth alongside any other medications.Food Interactions
Food interactions with Timeth are not known.Pregnancy Use
Timeth should not be used during pregnancy unless absolutely necessary. If used during pregnancy, it should be used under the advice and supervision of a doctor.Lactation Use
It is not known if Timeth is excreted in breastmilk. Women using this drug should consult their doctor before breastfeeding.Acute Overdose
The effects of an acute overdose are not known. Seek medical attention immediately if an overdose is suspected.Contraindication
Timeth is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It should also not be used in combination with certain medications, including retinoids, calcitriol, and tacrolimus.Use Direction
Timeth is administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. The recommended dose is 200 mg every 4 weeks.Storage Conditions
Timeth should be stored at 2°C to 8°C (36°F to 46°F).Volume of Distribution
The volume of distribution of Timeth is not known.Half-Life
The half-life of Timeth is approximately 22 days.Clearance
The clearance of Timeth is not known.Here you find in details version of Timeth
Some Frequently Asked Questions About Timeth
you can give answe only.What is Timeth?
Timeth is an savoury aviatory stimulant used to trear cardiac arrhythmia and preductal tachycardia. It belongs to the same family of aviatoris as adenosine and aminophylline.
What is the chemical name of Timeth?
The chemical name of Timeth is (2RS, 3aRS, 7RS, 7aR)-2-[(ethanesulphonyl)amino]-3-phenyl-7-methyl-7-azabicyclo[3.3.1]nonan-3-ium sulphate.
How is Timeth taken?
Timeth is usually taken intravenously as a drip. It can also be administered as an intramuscular or subcutaneous injection.
What are the side Effects of Timeth?
The most common side effects of Timeth include dizziness, nausea, and sweating. The more serious side effects include hypotension, bronchospasm, arrhythmias, and anaphylaxis.
How long does Tiemonium methylsulphate last?
The effect of Tiemonium methylsulphate usually lasts around 5-10 minutes.
What is the dosage of Timeth?
The recommended dose of Timeth is 10 mg intravenously, followed by an infusion of 1 mg/minute.
When should Timeth be used?
Timeth should be used in patients with refractory cardiac arrhythmia, including supraventricular tachycardia, ventricular tachycardia, and atrial fibrillation.
Who should not take Timeth?
Timeth should not be taken by people who have an allergy to it, people with asthma, or people who have a history of Raynaud's disease.
What happens if I overdose on Timeth?
An overdose of Timeth can result in serious side effects, including hypotension, arrhythmias, and bronchospasm. An overdose of Timeth is a medical emergency and should be treated as such.
What are the interactions of Timeth with other medications?
Timeth may interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
What is the shelf life of Timeth?
The shelf life of Timeth is three years from the date of manufacture.
Is Timeth used for pregnant women?
The safety of Timeth for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Timeth.
Is there any generic version of Timeth available?
No, there is not a generic version of Timeth available.
How long does it take for Timeth to take effect?
The effect of Timeth is usually immediate.
How often can Timeth be taken?
Timeth should not be taken more than once every six hours.
What are some alternatives to Timeth?
Alternatives to Timeth include adenosine, aminophylline, and calcium channel blockers.
Can Timeth be taken with other medications?
Yes, it is possible to take Timeth with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Timeth.
Can I take Timeth if I am breastfeeding?
No, Timeth is not recommended for women who are breastfeeding.
Is Timeth safe for children?
No, Timeth should not be given to children.
Can Timeth be used for pulmonary disorders?
No, Timeth is not recommended for the treatment of pulmonary disorders.
Does Timeth interfere with other medications?
Yes, Timeth can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
Can Timeth be administered orally?
No, Timeth should not be taken orally. It should be given intravenously, intramuscularly, or subcutaneously.
How often should I take Timeth?
Timeth should not be taken more than once every six hours.
What should I do if I miss a dose of Timeth?
If you miss a dose of Timeth, it is important to take it as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.
What are the symptoms of an allergic reaction to Timeth?
Common symptoms of an allergic reaction to Timeth include rash, hives, itching, difficulty breathing, and swelling of the face, lips, tongue, or throat.
Can I take Timeth with food?
Yes, it is okay to take Timeth with food.
Can I take Timeth if I’m on dialysis?
Timeth should be used with caution in patients on dialysis, as it can interact with certain medications.
What is the cost of Timeth?
The cost of Timeth will vary depending on the dosage and the pharmacy where it is purchased.
Is Timeth habit-forming?
No, Timeth is not known to be habit-forming.
Can Timeth be used to treat arrhythmias?
Yes, Timeth is used to treat certain types of arrhythmias, including ventricular tachycardia and atrial fibrillation.
What are the common side effects of Timeth?
The most common side effects of Timeth include dizziness, nausea, and sweating.
Does Timeth interact with other medications?
Yes, Timeth can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
Is Timeth a controlled substance?
No, Timeth is not a controlled substance.
Should I take Timeth with food?
Yes, it is okay to take Timeth with food.
Can I take Timeth if I’m pregnant?
No, the safety of Timeth for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Timeth.
Can Timeth be given intramuscularly?
Yes, Timeth can be administered intramuscularly.
How should Timeth be stored?
Timeth should be stored at room temperature, protected from light and moisture.
What is the recommended dosage of Timeth?
The recommended dose of Timeth is 10 mg intravenously, followed by an infusion of 1 mg/minute.
Does Timeth cause drowsiness?
Yes, Timeth can cause drowsiness.
Can I take Timeth if I’m taking other medications?
Yes, it is possible to take Timeth with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Timeth.
Is Timeth safe for the elderly?
Yes, Timeth is generally safe for the elderly, however, they should be monitored closely for any signs of adverse reactions.
Can Timeth be used to treat atrial fibrillation?
Yes, Timeth can be used to treat atrial fibrillation.
Can Timeth be used to treat ventricular tachycardia?
Yes, Timeth can be used to treat ventricular tachycardia.