Sennosides
Sennosides Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Sennosides is a brand name. Its generic name is Sennosides.
Introduction
Sennosides are natural laxatives derived from the dried leaves of theCassia senna, a plant that grows in Africa, India, and other parts of the Middle East and Asia. They are commonly found in over-the-counter (OTC) and prescription laxative products. Sennosides are available in various forms, including tablets, capsules, oral solutions, and suppositories. Sennosides are approved by the Food and Drug Administration (FDA) for the temporary relief of constipation.
Uses
Sennosides are used to treat constipation and promote bowel movement. They work by irritating and stimulating nerve endings in the walls of the intestines, increasing the amount of water the intestines absorb and drawing fluid into the bowel. This softens the stool, making it easier to pass.
Mechanism of Action
Sennosides work by irritating the large intestine. This stimulates fluid secretion and increases the movement of the intestinal muscles, which helps the stool move through the intestines and bowels more easily. The increased fluid in the intestines also softens the stool.
How Long Does It Take To Work?
Sennosides usually start working within 6 to 12 hours after intake. The effects can last up to 3 days.
Absorption
Sennosides are poorly absorbed in the gastrointestinal tract and are excreted largely unchanged in the feces.
Route of Elimination
Sennosides are eliminated primarily in the feces. A small amount is excreted in the urine.
Dosage
The dosage and strength of sennosides depend on the type of laxative and the patient’s individual needs. Sennosides are available in various forms, including tablets, capsules, oral solutions, and suppositories. Low-dose tablets typically contain up to 8.6mg of sennosides, while 30mg rectal suppositories are available. In general, adults and children over 12 years old should not exceed 30mg of sennosides per day.
Administration
Sennosides may be administered orally, rectally, or as an enema. Lower doses of sennosides are more effective when taken orally. The tablets, capsules, or solutions should be taken with a full glass of water. Suppositories are administered rectally and should be inserted as far as the finger can reach.
Side Effects
The side effects of sennosides may include abdominal cramping, diarrhea, nausea, dizziness, and headache. Serious side effects are rare but may include severe vomiting, bloody diarrhea, or an allergic reaction. If any of these side effects occur, contact your doctor right away.
Toxicity
Sennosides are generally safe to use when taken as directed. Long-term or excessive use of sennosides can be toxic and can damage the liver and the kidneys. Overdose can cause severe dehydration, electrolyte imbalances, and electrolyte disturbances. Seek medical attention immediately if you experience any of these symptoms.
Precaution
Before using sennosides, talk to your healthcare provider about any medications or supplements you currently take, including prescription and over-the-counter medications, vitamins, and herbal supplements. Also, tell your provider if you have kidney or liver disease, diabetes, heart failure, or any other medical condition. Your doctor may recommend a lower dose or advise against using sennosides altogether.
Interaction
Sennosides can interact with some medications and herbs. It is important to check with your healthcare provider to see if taking sennosides is safe. Common interactions include the anticoagulant warfarin, muscle relaxant baclofen, and antibiotics such as ciprofloxacin.
Disease Interaction
Those with gastrointestinal disorders should use caution when taking sennosides. People withabdominal pain, Crohn's disease, diverticular disease, ulcerative colitis, appendicitis, or any other abdominal disorder should talk to a healthcare provider before taking sennosides.
Drug Interaction
Sennosides can interact with certain medications. These include blood thinners, diuretics, digoxin, lithium, muscle relaxants, and antibiotics. Taking sennosides with these may increase the effects of the medications and may have undesired side effects. It is important to speak with your healthcare provider to ensure that taking sennosides is safe.
Food Interactions
There are no known food interactions with sennosides. However, it is important to take sennosides with enough water to help reduce the risk of abdominal cramping.
Pregnancy Use
Sennosides should not be used during pregnancy unless prescribed by a healthcare provider. There is not enough evidence to indicate that sennosides are safe for pregnant women. Women who are breastfeeding should consult a healthcare provider before taking sennosides.
Lactation Use
Sennosides are not recommended for use during lactation. There is not enough evidence to show that sennosides are safe for breastfeeding mothers or for their infants.
Acute Overdose
If an overdose of sennosides occurs, seek emergency medical attention right away. Overdose symptoms may include nausea, vomiting, diarrhea, stomach pain, dehydration, and electrolyte imbalances. Additionally, too much sennosides can lead to liver and kidney damage.
Contraindication
Sennosides are contraindicated in people with intestinal obstruction, abdominal pain, Crohn's disease, ulcerative colitis, appendicitis, or any other abdominal disorder. Sennosides are also contraindicated in people with kidney or liver disease, bleeding disorders, those taking certain medications, and those allergic to sennosides.
Use Direction
Sennosides should be taken with a full glass of water. They can be taken orally with tablets or capsules, rectally with suppositories, or as an enema. Lower doses are more effective when taken orally. Do not use more than the recommended dose or take it for longer than directed.
Storage Condition
Store sennosides at room temperature, away from heat and light. Keep medications in the original container and out of reach of children.
Volume of Distribution
It is unknown how much sennosides are distributed in body tissues.
Half Life
The half-life of sennosides is unknown.
Clearance
It is not known how sennosides are cleared from the body.
Here you find in details version of Sennosides
Some Frequently Asked Questions About Sennosides
What are Sennosides?
Sennosides are a type of laxative from the senna plant, also known as Cassia senna or Alexandria senna. They are used in some over-the-counter medicines to relieve constipation.
How do Sennosides work?
Sennosides work by stimulating contractions of the colon to draw water into it, which helps soften stools and promote regular bowel movements.
Are Sennosides safe?
Sennosides are generally considered safe when taken as directed, but they should not be used for more than one week at a time. It is also important to speak with a doctor before taking Sennosides if you have a medical condition or are taking other medications.
What are the side effects of Sennosides?
The most common side effects of Sennosides are abdominal cramps, nausea, vomiting, and diarrhea. If these symptoms worsen or persist, contact your doctor right away.
Are there any drugs that interact with Sennosides?
Sennosides can interact with certain medications, such as digoxin, warfarin, and certain antibiotics. It is important to speak with your doctor before taking Sennosides if you are taking any other medications.
What are the recommended dosage amounts for Sennosides?
The recommended dosage of Sennosides depends on the product or strength. It is important to follow the instructions on the medication or package insert and speak with your doctor or pharmacist if you have any questions about dosing.
Is it safe to take Sennosides while pregnant or breastfeeding?
Sennosides are not generally recommended during pregnancy, as they can pass into the placenta and may reach the baby. Sennosides can also pass into breast milk, so nursing mothers should use caution when taking Sennosides.
Are there any other natural laxatives I can take instead of Sennosides?
Yes, there are a few other natural laxatives that may be suitable when taken as directed. These include dandelion root, psyllium husk, slippery elm bark, and flaxseed.
Can I take Sennosides everyday?
No, Sennosides should not be taken for more than a week at a time. It is important to talk to your doctor before taking Sennosides, as taking too much can cause side effects.
Can I take Sennosides with other over-the-counter medications?
Yes, Sennosides can be taken with other over-the-counter medications, but it is important to speak with your doctor or pharmacist before taking any combination of medications to make sure it is safe.
What can I do to prevent constipation while taking Sennosides?
It is important to drink plenty of water and exercise regularly while taking Sennosides to help prevent constipation. Eating a high-fiber diet and avoiding spicy foods can also help.
Do Sennosides cause stomach cramps?
Yes, stomach cramps are one of the most common side effects of Sennosides. If the cramps become severe, it is important to speak with your doctor immediately.
Is Sennosides safe for children to take?
Sennosides should not be given to children under the age of 6 without speaking with a doctor first. For children 6 and over, a doctor can determine the appropriate dosage.
Is it safe to take Sennosides for a long period of time?
No, due to the potential side effects, Sennosides should not be taken for more than one week at a time. If you are having chronic constipation, it is important to speak with your doctor for other treatment options.
Can I take Sennosides with alcohol?
No, alcohol can increase the risk of certain side effects, such as nausea, vomiting, and stomach cramps. It is important to avoid alcohol while taking Sennosides.
How long does it take for Sennosides to work?
Sennosides usually take 12 to 72 hours to take effect. If you do not experience relief after three days, contact your doctor.
Are there any over-the-counter medications that contain Sennosides?
Yes, there are several over-the-counter medications that contain Sennosides. Some of the most common brands are Senokot, Ex-lax, and Dulcolax.
Can I take Sennosides with other medications?
Yes, Sennosides can be taken with other medications, but it is important to speak with a doctor or pharmacist first to make sure it is safe. Certain medications, such as digoxin, warfarin, and certain antibiotics, can interact with Sennosides.
Can Sennosides cause weight gain?
No, Sennosides should not cause weight gain. However, long-term use can worsen some underlying health conditions, such as electrolyte imbalances. It is important to talk to your doctor if you experience any weight gain while taking Sennosides.
Are Sennosides habit forming?
No, Sennosides are not habit forming. However, it is important to take them as directed and not use them for more than one week at a time.
Can Sennosides cause dehydration?
Yes, Sennosides can cause dehydration if taken in large doses or for too long. It is important to drink plenty of water while taking Sennosides, as this can help prevent dehydration.
Is it safe to take Sennosides for constipation caused by traveling?
Yes, traveling can often result in constipation. It is safe to take Sennosides to treat the constipation, but it should not be taken for more than a week. It is also important to speak to a doctor before taking Sennosides to make sure it is safe for you.
Can I take Sennosides with ibuprofen?
Yes, Sennosides can be taken with ibuprofen, but it is important to speak with a doctor or pharmacist before taking the combination to make sure it is safe. Certain medications can interact with Sennosides.
Are Sennosides safe for seniors to take?
Yes, Sennosides are generally considered safe for seniors to take when taken as directed. However, it is important to speak to a doctor before taking Sennosides to make sure it is safe for you.
Is it safe to take Sennosides with an antidepressant?
Yes, Sennosides can be taken with an antidepressant, but it is important to speak with a doctor or pharmacist before taking the combination to make sure it is safe. Certain medications can interact with Sennosides.
Can I take Sennosides if I have kidney disease?
No, Sennosides are not recommended to be taken by people with kidney disease. It is important to speak with a doctor before taking Sennosides if you have kidney disease.
Can I take Sennosides with hormonal birth control?
Yes, Sennosides can be taken with hormonal birth control, but it is important to speak with a doctor or pharmacist before taking the combination to make sure it is safe. Certain medications can interact with Sennosides.
Can Sennosides cause headaches?
Yes, headaches are one of the most common side effects of Sennosides. If you experience a headache that is severe or persistent, contact your doctor right away.
Can I take Sennosides while I am sick?
Yes, Sennosides are generally considered safe when taken as directed, but it is important to speak with your doctor before taking them. Certain medications can interact with Sennosides.
Can I take Sennosides if I am on a low sodium diet?
Yes, Sennosides can be taken if you are on a low sodium diet, but it is important to speak with a doctor or pharmacist before taking them to make sure they are safe for you.
Can Sennosides cause bloating and gas?
Yes, bloating and gas are common side effects of Sennosides. If these symptoms worsen or persist, contact your doctor right away.
What should I do if I forget to take my dose of Sennosides?
If you forget to take a dose of Sennosides, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose as scheduled.
Can I take Sennosides with a diuretic?
Yes, Sennosides can be taken with a diuretic, but it is important to speak with a doctor or pharmacist before taking the combination to make sure it is safe. Certain medications can interact with Sennosides.
Can I take Sennosides if I am diabetic?
Yes, Sennosides are generally safe for people with diabetes to take when taken as directed. However, it is important to speak with a doctor before taking Sennosides, as certain medications can interact with them.
Can I take Sennosides if I have high blood pressure?
Yes, Sennosides are generally safe for people with high blood pressure to take when taken as directed. However, it is important to speak with a doctor before taking Sennosides, as certain medications can interact with them.
Can I take Sennosides while I am taking antibiotics?
Yes, Sennosides can be taken with antibiotics, but it is important to speak with a doctor or pharmacist before taking the combination to make sure it is safe. Certain antibiotics can interact with Sennosides.
Can I take Sennosides if I am taking an anti-depressant?
Yes, Sennosides can be taken with an anti-depressant, but it is important to speak with a doctor or pharmacist before taking the combination to make sure it is safe. Certain medications can interact with Sennosides.
Can I take Sennosides while I am on insulin?
Yes, Sennosides can be taken with insulin, but it is important to speak with a doctor or pharmacist before taking the combination to make sure it is safe. Certain medications can interact with Sennosides.
How can I reduce the side effects of Sennosides?
The best way to reduce the side effects of Sennosides is to take them exactly as directed. Drinking plenty of water and avoiding spicy foods can also help reduce the side effects.
Can I take Sennosides with over-the-counter pain medications?
Yes, Sennosides can be taken with over-the-counter pain medications, but it is important to speak with a doctor or pharmacist before taking the combination to make sure it is safe. Certain medications can interact with Sennosides.
Can I take Sennosides if I have an allergy to sulfur medications?
Yes, Sennosides can be taken by people who have an allergy to sulfur medications, but it is important to speak with a doctor before taking them.
Can I take Sennosides if I have an ulcer?
No, Sennosides are not recommended to be taken by people with an ulcer. It is important to speak with a doctor before taking Sennosides if you have an ulcer.