Remol Forte

Remol Forte Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Remol Forte is a brand name. Its generic name is Paracetamol + Propoxyphene.

Remol Forte Introduction

Remol Forte is a combination of two medications: paracetamol and propoxyphene. It is used to reduce mild to moderate pain, muscle spasms, and fever. It is available in both an oral tablet and syrup form. While it is effective in treating pain, it should not be used for longer than a few days without consulting your doctor.

Uses For

Remol Forte is used to treat mild to moderate pain, muscle spasms, and fever. It can also be used to reduce inflammation and swelling. It is generally used to treat conditions such as: dental,period pain, headache, migraine, fever, cold and flu, muscle pain, joint pain, and nerves.

Mechanism of Action

Remol Forte works by blocking the production of certain inflammatory chemical messengers, such as prostaglandins. This prevents inflammation, which is the main source of pain and swelling. Paracetamol reduces pain by blocking the action of enzymes in the brain that generate pain signals. Propoxyphene is a type of opioid analgesic drug that produces a calming effect, allowing pain relief to occur.

How Long Does it Take to Work?

Remol Forte typically begins to work within 30 minutes after administration. The maximum effect is typically reached within an hour.

Absorption

Remol Forte is rapidly and completely absorbed when taken orally. The peak plasma concentration is between 60 - 120 minutes of taking the tablet.

Route of Elimination

Remol Forte is excreted in the urine via the kidneys.

Dosage

The adult dose of Remol Forte is typically one tablet (800 mg of paracetamol + 60 mg of propoxyphene) taken orally every 6 - 8 hours, as needed. The maximum dose is 8 tablets per day.

Administration

Remol Forte should be taken orally with a full glass of water. It should be taken before meals to reduce the risk of stomach irritation.

Side Effects

possible side effects of Remol Forte include: nausea, headache, dizziness, constipation, drowsiness, dry mouth, and fatigue. More serious side effects include: confusion, difficulty breathing, changes in heart rate, seizures, and agitation.

Toxicity

Consuming large amounts of Remol Forte over a short period of time may result in overdose and serious side effects. Overdoses of Remol Forte can lead to respiratory and cardiac arrest, and need to be treated immediately.

Precautions

Remol Forte should not be taken for longer than a few days without consulting your doctor. It should not be taken with alcohol, as this can increase sedative effects. People with comorbidities should only take Remol Forte with caution, and should consult their doctor first.

Interactions

Remol Forte should not be taken with other medications, such as anti-anxiety medications or sedatives, as this can result in serious side effects. Also, it may interact with certain other medications, such as acetaminophen, aspirin, ibuprofen, and warfarin, so they should also be avoided.

Disease Interactions

Remol Forte may worsen some medical conditions. These conditions include: asthma, COPD, bronchitis, liver disease, kidney disease, seizures, mental illness, and drug or alcohol addiction.

Drug Interactions

Remol Forte should not be taken with other medications, such as anti-anxiety medications or sedatives, as this can result in serious side effects. Other drugs that should be avoided while taking this combination medication include: aspirin, ibuprofen, warfarin, and acetaminophen.

Food Interactions

Remol Forte generally does not interact with food. However, it may be more effective if taken with food to avoid stomach irritation.

Pregnancy Use

Remol Forte should not be used by pregnant women as it may cause harm to the developing fetus.

Lactation Use

Remol Forte should not be used by nursing mothers, as it may be passed to the baby through breast milk.

Acute Overdose

An overdose of Remol Forte can lead to respiratory and cardiac arrest, and need to be treated immediately. If you suspect an overdose, contact your local Poison Control Center or an emergency room for assistance.

Contraindication

Remol Forte is contraindicated in people with hypersensitivity to either of the components, liver failure, impaired renal function, or in pregnant or lactating women. It is also not recommended for people with asthma, COPD, bronchitis, mental illness, or drug or alcohol addiction.

Use Directions

Remol Forte should be taken orally with a full glass of water. It should be taken before meals to reduce the risk of stomach irritation. The adult dose of Remol Forte is typically one tablet (800 mg of paracetamol + 60 mg of propoxyphene) taken orally every 6 - 8 hours, as needed. The maximum dose is 8 tablets per day.

Storage Condition

Remol Forte should be stored at room temperature away from light and moisture. It should be kept out of reach of children and pets.

Volume of Distribution

The volume of distribution of Remol Forte is 67.2 to 72.1 L.

Half Life

The half-life of Remol Forte is approximately 3.5 to 5.5 hours.

Clearance

The clearance of Remol Forte is approximately 19 - 25 mL/min/kg.

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