Rasagiline
Rasagiline Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Rasagiline is a brand name. Its generic name is Rasagiline.
Introduction
Rasagiline is an anti-Parkinsonism drug and MAO-B inhibitor used to treat symptoms of Parkinson's disease such as muscle stiffness, tremors, and other movement-associated conditions. It is taken orally in form of tablets or capsules and can provide long-term relief from symptoms.Uses_for
Rasagiline is prescribed primarily for treating the symptoms of Parkinson’s disease. It is also used as an adjunct therapy in combination with other medications for improved efficacy. It is used to treat nerve damage and other symptoms associated with Parkinsons Disease, such as muscle stiffness, tremor, slowing of movement, and imbalance.Mechanism of Action
Rasagiline works by inhibiting an enzyme called monoamine oxidase type B (MAO-B). MAO-B is responsible for breaking down dopamine, a neurotransmitter involved in motor control. By blocking this enzyme, rasagiline is able to increase the level of dopamine in the brain, which can reduce the symptoms associated with Parkinson’s disease.How long does it take to work?
The effects of rasagiline usually become evident within one week after starting treatment. However, some people may experience relief of symptoms within the first few days, while others may take longer to experience its benefits.Absorption
Rasagiline is well absorbed following oral administration. Its peak plasma concentration is reached approximately 1.5 to 3 hours after ingestion.Route of Elimination
Rasagiline is metabolized in the liver and is rapidly excreted in the urine.Dosage
The recommended dose of rasagiline for adults is 1 mg once daily, with or without food. It should be taken in the morning and no more than one tablet should be taken per day. The dose can be increased to 2 mg per day after approximately 1-2 weeks, and this dosage may be better tolerated.Administration
Rasagiline should be taken orally, with or without food. Do not crush, break, or chew the tablets as it may alter the effects of the drug.Side_Effect
Common side effects of rasagiline include nausea, dizziness, headache, dry mouth, constipation, and redness of the skin. More serious side effects include blurred vision, agitation, confusion, and fever.Toxicity
High doses of rasagiline can produce toxicity, the signs and symptoms of which include confusion, agitation, headache, headache, vomiting, and seizures. If any of these signs appear, seek medical attention immediately.Precaution
Rasagiline is not recommended for pregnant or breast-feeding women without physician approval. It may cause harm if taken with certain other drugs or when combined with certain foods and beverages. Therefore, it is important to provide your doctor with a list of all medications that you are currently taking, including vitamins and herbal supplements.Interaction
Rasagiline may interact with other medications or supplements, so it is important to always discuss your other medications with your doctor. It should not be taken with MAO inhibitors or drugs that affect the central nervous system.Disease Interaction
Patients with liver or kidney dysfunction, uncontrolled narrow-angle glaucoma, or history of seizures should use rasagiline with caution.Drug Interaction
Rasagiline may interact with other drugs, so it is important to provide your physician with a list of all medications and doses that you are currently taking, including vitamins and herbal supplements. This includes drugs which increase blood pressure and those which affect the central nervous system.Food Interactions
Rasagiline must not be taken simultaneously with high-tyramine containing foods or beverages such as aged cheese, wines, smoked-fish, and certain fruits.Pregnancy Use
Rasagiline should not be used during pregnancy, as it may cause harm to the fetus.Lactation Use
Rasagiline is not recommended for use during lactation due to the potential risk of adverse effects in a nursing infant.Acute Overdose
An acute overdose of rasagiline can lead to severe dizziness, confusion, tremors, convulsions, rapid heartbeat, and low blood pressure. Prompt medical attention is necessary in such cases.Contraindications
Rasagiline is contraindicated in patients with narrow-angle glaucoma, history of seizures, known hypersensitivity to rasagiline, and in those taking other drugs that affect the central nervous system.Use Direction
Rasagiline should be taken as prescribed by your physician or pharmacist. The recommended starting dose is 1 mg per day with or without food. The dose may be increased to 2 mg per day after 4 weeks. It should not be crushed or chewed as this may alter the effects of the drug.Storage Conditions
Rasagiline should be stored in its original packaging at room temperature, away from heat and moisture. Protect from light and keep out of reach of children.Volume of Distribution
The volume of distribution of rasagiline is approximately 2.1 liters per kilogram.Half Life
The half-life of rasagiline is approximately 8 hours.Clearance
Rasagiline is metabolized and eliminated primarily by the liver. It has an estimated clearance of 33.4 liters per hour per kilograms.Here you find in details version of Rasagiline
Some Frequently Asked Questions About Rasagiline
What is Rasagiline?
Rasagiline is a medication taken to treat the symptoms of Parkinson's disease. It works by increasing levels of dopamine in the brain, which can help to improve the coordination and movement of people with Parkinson's disease.
Does Rasagiline have any serious side effects?
Yes, Rasagiline may have serious side effects such as insomnia, nausea, dizziness, and hallucinations. If you experience any of these symptoms, you should stop taking Rasagiline and contact your doctor immediately.
Is Rasagiline addictive?
No, Rasagiline is not considered to be an addictive medication.
What are the benefits of taking Rasagiline?
Rasagiline can help to improve the coordination and movement of people with Parkinson's Disease. It can also reduce the severity of some of the symptoms of Parkinson's Disease such as tremors and rigidity.
What is the recommended dosage for Rasagiline?
The recommended dosage for Rasagiline is 1 mg per day. Your doctor may adjust the dosage depending on how you respond to the medication.
When should I take Rasagiline?
Rasagiline is usually taken once a day, preferably after a meal.
How long does it take for Rasagiline to start working?
The effects of Rasagiline may take up to four weeks to become apparent. It is important to continue taking Rasagiline even if you don't feel any immediate effects.
Can I take Rasagiline with other medications?
It is important to always consult your doctor before taking any medications in combination with Rasagiline. Certain medications may interact with Rasagiline and cause serious side effects.
Can I take Rasagiline while pregnant?
It is not recommended to take Rasagiline while pregnant. If you are pregnant or planning on becoming pregnant, make sure to consult your doctor first.
Can I take Rasagiline while breastfeeding?
It is not recommended to take Rasagiline while breastfeeding as it can pass into breast milk. Talk to your doctor about the best option for you.
Can I drink alcohol while taking Rasagiline?
It is not recommended to drink alcohol while taking Rasagiline as it can increase the risk of side effects. Talk to your doctor if you wish to consume alcohol while taking Rasagiline.
Can I take Rasagiline with anti-depressants?
Yes, Rasagiline can be taken with most anti-depressant medications. However, it is important to consult your doctor before taking any medications in combination with Rasagiline.
Can I take Rasagiline with anti-anxiety medications?
Yes, Rasagiline can be taken with most anti-anxiety medications. However, it is important to consult your doctor before taking any medications in combination with Rasagiline.
Can I take Rasagiline with anti-psychotic medications?
Yes, Rasagiline can be taken with most anti-psychotic medications. However, it is important to consult your doctor before taking any medications in combination with Rasagiline.
Can I take Rasagiline with blood pressure medications?
Yes, Rasagiline can be taken with most blood pressure medications. However, it is important to consult your doctor before taking any medications in combination with Rasagiline.
Can I take Rasagiline with seizure medications?
Yes, Rasagiline can be taken with most seizure medications. However, it is important to consult your doctor before taking any medications in combination with Rasagiline.
Can I take Rasagiline with antibiotics?
Yes, Rasagiline can be taken with most antibiotics. However, it is important to consult your doctor before taking any medications in combination with Rasagiline.
Can I take Rasagiline with antihistamines?
Yes, Rasagiline can be taken with most antihistamines. However, it is important to consult your doctor before taking any medications in combination with Rasagiline.
Is Rasagiline covered by insurance?
This will depend on your individual insurance plan. Contact your insurance provider to find out if they cover Rasagiline.
How long should I keep taking Rasagiline?
You should continue taking Rasagiline until your doctor tells you to stop. Do not stop taking Rasagiline without talking to your doctor first.
What should I do if I miss a dose of Rasagiline?
If you miss a dose of Rasagiline, take it as soon as you remember. However, if it is almost time for your next dose, simply skip the missed dose and take your next dose on time.
Can I overdose on Rasagiline?
Yes, taking too much Rasagiline can be toxic and could cause serious side effects. If you think you may have taken too much Rasagiline, contact your doctor or poison control center right away.
Can I buy Rasagiline over-the-counter?
No, Rasagiline is not available over-the-counter. It can only be obtained with a prescription from your doctor.
How should I store Rasagiline?
Rasagiline should be stored at room temperature, away from moisture, heat, and direct light. Keep the medication out of reach of children and pets.
Can I get a generic version of Rasagiline?
No, there is no generic version of Rasagiline currently available.
Is a generic version of Rasagiline available in other countries?
No, at this time there is no generic version of Rasagiline available in any other countries.
How long does Rasagiline stay in the body?
Rasagiline has a half-life of approximately 8 hours. This means that it will take about 40 hours for it to be completely eliminated from the body.
Do I need to have regular blood tests while taking Rasagiline?
Your doctor may want you to have regular blood tests in order to monitor your blood levels while taking Rasagiline. Follow your doctor's instructions for any necessary laboratory tests.
Can I take Rasagiline with vitamins?
Yes, it is generally safe to take Rasagiline with vitamins. However, it is important to consult your doctor before taking any medications in combination with Rasagiline.
Can I take Rasagiline with herbal supplements?
Yes, it is generally safe to take Rasagiline with herbal supplements. However, it is important to consult your doctor before taking any medications in combination with Rasagiline.
Can I take Rasagiline with over-the-counter medications?
Yes, it is generally safe to take Rasagiline with over-the-counter medications. However, it is important to consult your doctor before taking any medications in combination with Rasagiline.
What are the possible drug interactions with Rasagiline?
Rasagiline can interact with certain medications, such as blood pressure medications and seizure medications. Make sure to tell your doctor about all medications you are taking in order to reduce the risk of drug interactions.
Can I take Rasagiline with non-steroidal anti-inflammatory drugs (NSAIDs)?
Yes, it is generally safe to take Rasagiline with non-steroidal anti-inflammatory drugs (NSAIDs). However, it is important to consult your doctor before taking any medications in combination with Rasagiline.
If I am taking Rasagiline, can I still drink caffeine?
Yes, you can still drink caffeinated beverages while taking Rasagiline. However, drinking too much caffeine can increase the risk of side effects, so it is best to stick to moderate amounts.
Will taking Rasagiline affect my ability to drive or operate machinery?
Rasagiline may cause dizziness or drowsiness, so it is important to avoid driving and operating machinery if you experience these symptoms.
Can I take an extra dose of Rasagiline if I am feeling very tired?
No, it is not recommended to take extra doses of Rasagiline. If you are feeling very tired, contact your doctor and do not take any extra doses of the medication.
Should I avoid any foods while taking Rasagiline?
You should avoid foods that are high in tyramine while taking Rasagiline, as they can interact with the medication and cause side effects. Examples of tyramine-rich foods include aged cheeses, cured meats, canned meats, and fermented fish.
Can I take a multivitamin while taking Rasagiline?
Yes, it is generally safe to take a multivitamin while taking Rasagiline. However, it is important to consult your doctor before taking any medications in combination with Rasagiline.