Quinaprim
Quinaprim Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Quinaprim is a brand name. Its generic name is Primaquine.
Introduction
Quinaprim is an antimalarial medication used to treat and prevent certain types of malaria. It is also used as a prophylaxis, which is used to prevent the further spread of malaria after initial treatment. Quinaprim belongs to a group of antimalarials called 8-amino-quinolines.Uses For
Quinaprim is used to treat and prevent certain types of malaria caused by Plasmodium falciparum and Plasmodium vivax. It is also used as a prophylaxis (preventive medication) against further accusations of malaria in travelers in areas that are infected with Plasmodium vivax and Plasmodium falciparum. Quinaprim should not be used in children under 8 years old.Mechanism Of Action
Quinaprim works by interfering with two essential proteins involved in the synthesis of DNA in the malaria parasite. It inhibits the enzyme dihydrofolate reductase and interferes with the electron transport system, both of which are essential for the parasite to survive. Quinaprim also has a role in preventing the transmission of the malaria parasite to uninfected mosquito vectors.How Long Does It Take To Work?
Quinaprim usually takes effect within 1-2 hours of ingestion. The effects of Quinaprim can last up to 48 hours, so it is important to take the medication as prescribed by a physician.Absorption
Quinaprim is absorbed quickly and completely from the gastrointestinal tract. It has an apparent volume of distribution of 1.31 L/kg and an apparent bioavailability of 42%.Route Of Elimination
Quinaprim is eliminated primarily by the kidneys. It has an elimination half-life of 23 hours.Dosage
The recommended dosage for Quinaprim depends on the condition being treated. For prophylaxis, the usual dosage is 15mg orally once daily for 7 days. For treatment of acute malaria, the usual dosage is 15mg orally once daily for 14 days. It is important to take Quinaprim exactly as prescribed by a physician.Administration
Quinaprim should be taken with food or a full glass of water. It should be taken at the same time each day to maintain an even level of medication in the bloodstream.Side Effects
The most common side effects of Quinaprim include nausea, vomiting, headache, dizziness, loss of appetite, hair loss, hepatitis, rash, and anemia.Toxicity
The toxic effects of Quinaprim include changes in behavior, disorientation, difficulty breathing, and seizures.Precautions
Before taking Quinaprim, it is important to inform your physician if you have liver or kidney disease, blood disorders, glucose-6-phosphate dehydrogenase (G6PD) deficiency, or any allergies.Interactions
Quinaprim can interact with other drugs, including antacids, certain antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs).Disease Interactions
Quinaprim can worsen certain diseases, including cancer, diabetes, anemia, and liver or kidney disease.Drug Interactions
Quinaprim can interact with certain drugs, including antacids, certain antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs).Food Interactions
It is important to take Quinaprim with food to reduce the risk of interactions.Pregnancy use
Quinaprim should not be used in pregnant women, as it may cause serious birth defects.Lactationuse
Quinaprim should not be used while breastfeeding as it may be passed to the infant through breast milk.Acute Overdose
The symptoms of an acute overdose may include severe abdominal pain, nausea, vomiting, seizures, and difficulty breathing. If you suspect an overdose, contact your local poison control center or emergency room immediately.Contraindication
Quinaprim should not be used in people with certain conditions, including porphyria, G6PD deficiency, severe anemia, and hemolytic anemia.Use Direction
Quinaprim should be taken as prescribed by a physician. Do not take more or less than the recommended amount.Storage Condition
Quinaprim should be stored in a cool, dry place, at room temperature. Keep out of reach of children and pets.Volume Of Distribution
Quinaprim has an apparent volume of distribution of 1.31 L/kg.Half Life
Quinaprim has an elimination half-life of 23 hours.Clearance
Quinaprim is eliminated primarily by the kidneys.Here you find in details version of Quinaprim
Some Frequently Asked Questions About Quinaprim
What is Quinaprim?
Quinaprim is an antimalarial medication used to treat and prevent malaria infection.
How does Quinaprim work?
Quinaprim works by killing the malaria parasites in the liver. It also prevents the parasites from multiplying and spreading.
What is the active ingredient in Quinaprim?
The active ingredient in Quinaprim is primaquine phosphate.
How long does it take for Quinaprim to work?
Quinaprim typically begins to work within 24 hours of taking the medication.
What are the side effects of Quinaprim?
Typical side effects of Quinaprim include headache, nausea, dizziness, vomiting, loss of appetite, and abdominal pain.
Is Quinaprim safe to take during pregnancy?
Quinaprim should not be used during pregnancy, as it can cause harm to the unborn baby.
Is Quinaprim safe for children?
Quinaprim is generally not recommended for use in children under the age of 16.
Does Quinaprim interact with other medications?
Yes, Quinaprim can interact with other medications, including antacids, antibiotics, antivirals, and nonsteroidal anti-inflammatory drugs (NSAIDs).
What is the recommended dosage of Quinaprim?
The recommended dosage of Quinaprim is 0.5-1 tablet per day for adults and 0.25-0.5 tablet per day for children aged 16 and over.
What is the difference between Quinaprim and chloroquine?
Quinaprim is an antimalarial medication used to treat and prevent malaria infections, while chloroquine is an antimalarial medication used to treat and prevent malaria infections and also reduce inflammation in some autoimmune diseases.
Does Quinaprim need to be taken with food?
It is recommended to take Quinaprim with food to reduce the risk of stomach upset.
What should I do if I miss a dose of Quinaprim?
If you miss a dose of Quinaprim, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and take your next dose at the regular time.
How long should I take Quinaprim?
The length of time that Quinaprim should be taken depends on your individual medical condition. Your doctor will advise you on how long to take the medication.
Can I drink alcohol while taking Quinaprim?
It is not recommended to drink alcohol while taking Quinaprim, as it may increase the risk of side effects.
What is the generic name for Quinaprim?
The generic name for Quinaprim is primaquine phosphate.
Is Quinaprim an antibiotic?
No, Quinaprim is not an antibiotic; it is an antimalarial medication.
Can I buy Quinaprim over the counter?
No, Quinaprim is a prescription-only medication and cannot be bought over the counter.
Can Quinaprim be used to treat other conditions?
No, Quinaprim is only used to treat and prevent malaria infection.
What is the price of Quinaprim?
The price of Quinaprim varies depending on the manufacturer and dosage. Your pharmacy can provide you with the most up-to-date pricing information.
Can Quinaprim cause liver damage?
Yes, Quinaprim can cause liver damage in some individuals. If you have any liver problems, speak to your doctor before taking Quinaprim.
Does Quinaprim cause drowsiness?
Yes, Quinaprim can cause drowsiness in some individuals. If you experience drowsiness, do not drive or operate machinery.
Does Quinaprim interact with birth control?
Yes, Quinaprim can interact with birth control. It is recommended to use another form of birth control while taking Quinaprim.
Does Quinaprim cause diarrhea?
Yes, Quinaprim can cause diarrhea in some individuals.
Is Quinaprim used to treat malaria?
Yes, Quinaprim is used to treat and prevent malaria infection.
Does Quinaprim cause weight gain?
No, Quinaprim does not typically cause weight gain.
Can I take Quinaprim with other medications?
It is important to tell your doctor about any other medications you are taking before taking Quinaprim, as some medications can interact with Quinaprim.
Will Quinaprim work against all strands of malaria?
Quinaprim has been shown to be effective against most strains of malaria; however, it may not work against all strains.
Does Quinaprim cause loss of appetite?
Yes, Quinaprim can cause loss of appetite in some individuals.
When should I start taking Quinaprim?
Your doctor will advise you as to when you should start taking Quinaprim. It is typically recommended to start taking the medication 1-2 days prior to traveling to a malaria-endemic region.
Is Quinaprim safe to take if I have kidney problems?
Yes, Quinaprim is generally considered safe to take if you have kidney problems; however, your doctor may need to adjust the dose or monitor your condition more closely.
Can I take Quinaprim if I have high blood pressure?
Yes, Quinaprim can be taken if you have high blood pressure; however, your doctor may need to adjust the dose or monitor your condition more closely.
Can I take Quinaprim for longer than the recommended time?
No, Quinaprim should only be taken for the recommended time, as it can cause serious side effects if taken for longer than recommended.
Can Quinaprim be split in half?
Yes, Quinaprim tablets can be safely split in half in order to reduce the dose taken.
What are the symptoms of an overdose on Quinaprim?
Symptoms of an overdose on Quinaprim may include headache, nausea, dizziness, vomiting, and abdominal pain.
Can Quinaprim cause an allergic reaction?
Yes, Quinaprim can cause an allergic reaction in some individuals. Stop taking the medication and seek medical attention if you experience any symptoms of an allergic reaction, such as rash, itching, or swelling.
Is Quinaprim effective against Plasmodium falciparum malaria?
Yes, Quinaprim has been found to be effective against Plasmodium falciparum malaria.
Does Quinaprim cause hair loss?
No, Quinaprim does not typically cause hair loss.
Can I take Quinaprim if I'm breastfeeding?
No, Quinaprim should not be taken while breastfeeding, as it can pass into breast milk and cause harm to the baby.
Does Quinaprim need to be taken with food?
It is recommended to take Quinaprim with food to reduce the risk of stomach upset.
What should I do if I get an upset stomach while taking Quinaprim?
If you experience an upset stomach while taking Quinaprim, try taking the medication with food. If your symptoms persist, speak to your doctor.
Does Quinaprim cause drowsiness?
Yes, Quinaprim can cause drowsiness in some individuals. If you experience drowsiness, do not drive or operate machinery.