Polocaine Dental
Polocaine Dental Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Polocaine Dental is a brand name. Its generic name is Mepivacaine.
Polocaine Dental
Polocaine Dental is a local anesthetic pain reliever that has been in use since the mid-1960s. It is a type of amino amide of the ester class, that is most commonly used as a nerve block or for dental procedures. The drug stops the flow of certain signals along the nerves towards the brain and creates a numb sensation and reduces the feeling of pain in the affected area.
Uses for Polocaine Dental
Polocaine Dental is commonly used for nerve blocks, spinal anesthesia, and dental procedures. It can be used to reduce pain during minor medical procedures. Additionally, it is used epidurally or infiltration as a local anesthetic for percutaneous nerve block or regional anesthetic. Polocaine Dental may also be used for other conditions as determined by your doctor.
Mechanism of Action
Polocaine Dental blocks nerve conduction by stopping the flow of certain signals along the nerves towards the brain. The specific drugs inhibit neuronal conduction by blocking the influx of sodium into the neuron during the action potential, reducing both its threshold for stimulation and its absolute refractory period. This effect can last for several hours after the medication has been administered.
How Long Does It Take to Work?
Polocaine Dental usually begins to take effect within 2-5 minutes after the injection. However, the effects may last for several hours after the medication has been administered.
Absorption
Polocaine Dental is rapidly and extensively absorbed after its injection either intramuscularly or epidurally. Its continuous infusion is reported to be more effective than local anesthetic bolus injection.
Route of Elimination
Polocaine Dental is metabolized in the liver and its metabolites are excreted in the urine.
Dosage
The dosage of mepivacaine varies according to the procedure being performed. It is usually administered via intramuscular or epidural injection. The accepted dosing of mepivacaine for various procedures are as follows:
- Nerve Block: 0.5% to 1% concentration: 2 mg/kg
- Epidural Anesthesia: 0.5% to 1% concentration: 3 mg/kg
- Percutaneous Nerve Block: 1% to 2% concentration: 2 to 5 mL
- Spinal Anesthesia: 0.5 to 1% concentration: 5 mg/kg
Administration
Polocaine Dental should only be administered by a qualified healthcare professional. It is typically injected into the muscle or into the epidural space. For nerve blocks, the concentration and dosage should be determined by a healthcare provider depending on the procedure being performed.
Side Effect
The most common side effects associated with the use of mepivacaine include headache, lightheadedness, numbness, and nausea. Other side effects may include rash, itching, seizures, and irregular heartbeat. If swelling, burning, or persistent pain occur, seek medical attention immediately.
Toxicity
Polocaine Dental has a low oral LD50 compared to other local anesthetics, indicating a high risk of toxicity in the event of an overdose. Symptoms associated with toxicity can include twitching, severe headaches, seizures, and a slowed heartbeat. If an overdose occurs, seek medical attention immediately.
Precaution
Polocaine Dental should not be used in patients who are pregnant or breastfeeding, as it can cause harm to the fetus or newborn infant. Additionally, it should be used with caution in patients with kidney or liver diseases, as they may experience increased levels of toxicity. Patients with cardiac disease should be monitored closely as mepivacaine can cause a decrease in blood pressure, an irregular heartbeat, and in some cases, cardiac arrest.
Interaction
Polocaine Dental may interact with other medications, such as muscle relaxants, anticoagulants, antihypertensives, and other local anesthetics. Additionally, it may interact with substances such as alcohol, nicotine, and illicit drugs. Patients should inform their healthcare provider of any medications they are taking, prior to receiving mepivacaine.
Disease Interaction
Polocaine Dental may interact with medical conditions such as liver disease, heart disease, respiratory depression, seizure disorder, and pregnancy. It is important for patients to inform their healthcare provider of any pre-existing medical condition before receiving the medication.
Drug Interaction
Polocaine Dental may interact with other medications, which can lead to increased side effects, decreased effectiveness, or even a toxic reaction. When taking mepivacaine, patients should inform their healthcare provider of all other medications they are taking, including over the counter medications, vitamins, and herbal supplements.
Food Interactions
Polocaine Dental may interact with certain foods and beverages, including alcohol. It is important to inform your doctor of any known food allergies or dietary restrictions, prior to taking the medication.
Pregnancy Use
Polocaine Dental should not be used during pregnancy. It has been associated with an increased risk of adverse side effects and fetal abnormalities. Talk to your doctor about the risks and benefits before using the medicine during pregnancy.
Lactation Use
Polocaine Dental should not be used while breastfeeding. It can pass into the breast milk and cause side effects in the nursing infant. Therefore, it is important to discuss the risks and benefits with your doctor before using the medication while breastfeeding.
Acute Overdose
In the event of an acute overdose, symptoms may include twitching, severe headaches, confusion, seizures, slowed heartbeat, and loss of consciousness. Seek medical attention immediately if an overdose is suspected.
Contraindication
Polocaine Dental should not be used in patients who have a history of hypersensitivity to the drug, or to any of its components. It should also be used with caution in patients with certain medical conditions, such as liver or kidney disease, or cardiac disorders.
Use Direction
Polocaine Dental should be administered under the supervision of a qualified healthcare professional in a hospital or clinical setting. The dose and concentration of the medication should be determined by a healthcare provider depending on the procedure being performed. Patients should follow their healthcare provider's instructions carefully.
Storage Condition
Polocaine Dental should be stored at a controlled room temperature, between 59°F and 86°F (15°C and 30°C). Do not freeze and protect from light. Do not use the product if the expiration date has passed.
Volume of Distribution
The volume of distribution of mepivacaine is 0.2 - 0.4 L/kg.
Half Life
Polocaine Dental has a half-life of 1-2 hours.
Clearance
Polocaine Dental is mainly cleared through the kidneys. The renal clearance of mepivacaine is 0.04 mL/min/kg.
Here you find in details version of Polocaine Dental
Some Frequently Asked Questions About Polocaine Dental
What is Polocaine Dental?
Polocaine Dental is a local anesthetic commonly used for numbing up small areas of skin and mucous membranes. It is most commonly used in dental procedures, but it also can be used for a variety of other minor surgeries such as cosmetic procedures, or as a local anesthetic for pain relief.
How does Polocaine Dental work?
Polocaine Dental works by blocking the nerve impulses that would normally send pain signals to the brain. It does this by preventing the passage of sodium ions into the nerve cells, which is necessary for the cells to transmit pain signals. This numbs the area, preventing the patient from feeling any pain.
What are the side effects of Polocaine Dental?
The most common side effect of Polocaine Dental is a mild burning sensation at the injection site. Other side effects may include nausea, itching, and swelling. Most of these side effects are mild and do not last long. Rarely, more serious side effects such as allergic reactions or seizures can occur.
How long does Polocaine Dental last?
The duration of Polocaine Dental's effect depends on how much of the drug was used and the location in which it was injected. Generally, the effects of a single Polocaine Dental injection will last between two and four hours.
Is Polocaine Dental safe?
Yes, Polocaine Dental is safe when it is administered properly. It is a medication that is used to block the sensations of pain by numbing an area, making it useful for a variety of surgeries and procedures. Your health care provider should be consulted for more information.
Can Polocaine Dental be used during pregnancy?
Yes, Polocaine Dental can be used during pregnancy. However, it is important that you inform your doctor if you are pregnant before the procedure is done, as there may be certain risks or precautions that need to be taken.
Is Polocaine Dental habit forming?
No, Polocaine Dental is not habit forming. It is a local anesthetic that is only used to temporarily numb the area where it is injected, and it does not have any effects on the user's mental or emotional state.
Can Polocaine Dental be used on children?
Yes, Polocaine Dental can be used on children if it is necessary. However, it is important for parents to consult with their child's physician before the procedure to make sure it is safe for the child.
How should Polocaine Dental be stored?
Polocaine Dental should be stored in a dry place at room temperature. It should be kept away from direct sunlight or heat and not be placed in the refrigerator or freezer.
What if I miss a dose of Polocaine Dental?
If you miss a dose of Polocaine Dental, it is best to consult with your doctor for instructions. Polocaine Dental is not a medication that is taken orally, so there is no need to make up for the missed dose.
Can I buy Polocaine Dental over the counter?
No, Polocaine Dental is not available over the counter. It is a prescription medication and should only be administered by a medical professional.
What is the cost of Polocaine Dental?
The cost of Polocaine Dental varies depending on the dosage and the quantity purchased. Generally Polocaine Dental injection solutions cost between $10 and $25 per vial.
What should I avoid while taking Polocaine Dental?
It is important to avoid driving or other activities that require alertness while taking Polocaine Dental. You should also avoid drinking alcohol or taking any sedatives or sleeping pills while taking Polocaine Dental.
Can Polocaine Dental be used on cats and dogs?
Yes, Polocaine Dental can be used on cats and dogs if it is necessary. However, it is important to only use Polocaine Dental that is prescribed for use on animals, as using human-grade drugs may be dangerous for animals.
What should I tell my doctor before taking Polocaine Dental?
Before taking Polocaine Dental, you should tell your doctor about all medications and supplements you are currently taking, including any herbal or natural remedies. You should also tell your doctor if you have any pre-existing medical conditions or allergies.
What is the recommended dosage of Polocaine Dental?
The recommended dosage of Polocaine Dental varies depending on the procedure and the patient's age and weight. Your doctor or health care provider can provide more information about the correct dosage for your individual case.
Is Polocaine Dental available in generic form?
Yes, Polocaine Dental is available in generic form. Generic Polocaine Dental has the same active ingredients as brand-name Polocaine Dental and works the same way in the body.
Does Polocaine Dental have any interaction with other drugs?
Yes, Polocaine Dental may have interactions with some drugs and medications. Before taking Polocaine Dental, you should always inform your doctor or health care provider of any other drugs or supplements that you are currently taking.
Does Polocaine Dental have any side effects in the elderly?
Yes, elderly patients may be more likely to experience certain side effects of Polocaine Dental than younger patients. These side effects may include dizziness, confusion, blurred vision, and drowsiness. You should always inform your doctor if you are elderly or have any pre-existing medical conditions before taking Polocaine Dental.
Can I give a 2-year-old a dose of Polocaine Dental?
No, Polocaine Dental should not be administered to a 2-year-old. It should only be given to children under the age of 12 with the approval of a doctor or health care provider.
What is the maximum dosage of Polocaine Dental?
The maximum dosage of Polocaine Dental depends on the procedure and the individual patient. The exact dosage should always be determined by your doctor or health care provider.
Will Polocaine Dental help reduce swelling?
No, Polocaine Dental's primary purpose is to block nerve impulses which causes numbness. It will not help reduce swelling, but it may provide pain relief.
Can Polocaine Dental be used in the eyes?
Yes, Polocaine Dental can be used in the eyes for certain types of surgeries. However, it is important to talk to your doctor or health care provider before using Polocaine Dental in the eyes.
How long does it take for Polocaine Dental to take effect?
Polocaine Dental typically takes effect within a few minutes of the injection. The effects of a single injection of Polocaine Dental will typically last between two and four hours.
Can I take Polocaine Dental while breastfeeding?
No, you should not take Polocaine Dental while breastfeeding. Polocaine Dental is not safe for use in lactating women and could be transferred to the infant through breast milk.
Can I use Polocaine Dental on a large area?
No, Polocaine Dental should not be used on large areas of the body because it can cause side effects such as nausea, trembling, and seizures. If you need to numb a large area, you should speak to your doctor for alternative options.
Can Polocaine Dental be used on open wounds?
No, Polocaine Dental should not be used on open wounds or areas of skin that have been damaged or irritated. Polocaine Dental should only be used when the skin is intact.
Are there any alternatives to Polocaine Dental?
Yes, there are other local anesthetics that can be used in place of Polocaine Dental. Lidocaine and bupivacaine are two of the more commonly used local anesthetics.
What should I do if I experience a serious side effect from Polocaine Dental?
If you experience a serious side effect or an allergic reaction from Polocaine Dental, you should seek emergency medical attention immediately. Signs of an allergic reaction include difficulty breathing, hives, or swelling of the face, tongue, or throat.
Can Polocaine Dental be used on broken skin?
No, Polocaine Dental should not be used on broken or damaged skin. The drug can cause serious side effects when applied to open wounds, so you should speak to your doctor before using it on any broken skin.
Can I use Polocaine Dental on my lip?
Yes, Polocaine Dental can be used on the lips if it is necessary. However, it can cause a burning sensation when injected, so it should only be used as a last resort.
Is Polocaine Dental safe for long-term use?
No, Polocaine Dental is meant for short-term use only and should not be used for extended periods of time. Prolonged use of Mepivaciane can cause adverse effects on the patient's health.
Can I take Polocaine Dental if I have diabetes?
Yes, you can take Polocaine Dental if you have diabetes. However, it is important to inform your doctor if you have any pre-existing conditions before taking Polocaine Dental.
How quickly does Polocaine Dental take effect?
Polocaine Dental usually takes effect within a few minutes of the injection. The effects of a single injection of Polocaine Dental will typically last between two and four hours.