PNG

PNG Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? PNG is a brand name. Its generic name is Gramacidin + Neomycin + Polymixin B.

Introduction

Gramacidin, Neomycin and Polymixin B are antibiotics. They are used to treat infections caused by certain bacteria.

Uses

Gramacidin, Neomycin and Polymixin B are used to treat bacterial infections. Common conditions that respond to this medication include urinary tract infections, skin infections, wound infections, ear infections, and other bacterial infections.

Mechanism of Action

Gramacidin, Neomycin and Polymixin B work by interfering with the production of proteins needed by the bacteria to survive. This prevents the bacteria from growing and multiplying and eventually leads to their death.

How Long Does It Take to Work

The effects of Gramacidin, Neomycin and Polymixin B can begin in as little as 24 to 48 hours. It is important to take your medication as prescribed for the full duration that your doctor prescribes.

Absorption

Gramacidin, Neomycin and Polymixin B are all absorbed from the gastrointestinal tract. The time it takes for these medications to be absorbed and reach peak concentrations varies from person to person.

Route of Elimination

Gramacidin, Neomycin and Polymixin B are eliminated from the body primarily through the kidneys.

Dosage and Administration

The dose and method of administration of Gramacidin, Neomycin and Polymixin B will vary from patient to patient. Your doctor will be able provide guidance regarding the dosage and method of administration of this medication.

Side Effects

Common side effects of Gramacidin, Neomycin and Polymixin B include nausea, vomiting, rash, headache, dizziness, and diarrhea. Less common side effects include jaundice, abdominal pain, and changes in skin tone.

Toxicity

The toxicity of Gramacidin, Neomycin and Polymixin B can vary from person to person. High doses of these antibiotics can cause serious side effects and should be avoided.

Precautions

Gramacidin, Neomycin and Polymixin B should be used with caution in patients with kidney disease, liver disease, or any other medical condition. It is important to inform your doctor of any previous medical conditions you have before taking this medication.

Interactions

Gramacidin, Neomycin and Polymixin B may interact with other medications, including antacids, anticonvulsants, and birth control pills. It is important to inform your doctor of any medications or supplements you are taking.

Disease Interactions

Gramacidin, Neomycin and Polymixin B may interact with certain diseases, including kidney disease, liver disease, diabetes, and asthma. It is important to inform your doctor if you have any conditions before taking this medication.

Drug Interactions

Gramacidin, Neomycin and Polymixin B may interact with some other medications. Be sure to inform your doctor of any medications you are taking before starting this medication.

Food Interactions

Gramacidin, Neomycin and Polymixin B may interact with certain foods. It is important to tell your doctor if you are taking any dietary supplements or eating certain foods before taking this medication.

Pregnancy Use

Gramacidin, Neomycin and Polymixin B should be used with caution in pregnant women. Be sure to tell your doctor if you are pregnant before taking this medication.

Lactation Use

Gramacidin, Neomycin and Polymixin B should be used with caution in breastfeeding women. Be sure to tell your doctor if you are breastfeeding before taking this medication.

Acute Overdose

An acute overdose of Gramacidin, Neomycin and Polymixin B can be dangerous. Look for signs of an overdose such as nausea, vomiting, dizziness, and confusion.

Contraindications

Gramacidin, Neomycin and Polymixin B should not be used in patients with a known allergy or sensitivity to any of the ingredients in this medication.

Use Direction

Gramacidin, Neomycin and Polymixin B should be taken exactly as prescribed by your doctor. It is important to follow your doctor's instructions for the safe and effective use of this medication.

Storage Condition

Gramacidin, Neomycin and Polymixin B should be stored at room temperature away from heat and moisture. Make sure to keep the medication out of reach of children.

Volume of Distribution

Gramacidin, Neomycin and Polymixin B have a volume of distribution of approximately 0.16 L/kg.

Half Life

Gramacidin, Neomycin and Polymixin B have a half life of approximately 6 to 8 hours in the body.

Clearance

Gramacidin, Neomycin and Polymixin B have an average clearance of approximately 6 to 8 mL/min/kg.

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