PMS Benztropine
PMS Benztropine Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? PMS Benztropine is a brand name. Its generic name is Benzatropine.
PMS Benztropine Introduction
Benztropine is an anticholinergic medication used to treat certain neurological conditions or side effects from other medications. It works by blocking a certain type of neurotransmitter to reduce or prevent its effects.
Uses for PMS Benztropine
Benztropine is prescribed to treat the symptoms of Parkinson’s disease, some types of anxiety, and to help reduce the side effects of other medications. It is also approved to treat a rare condition called symptomatic orthostatic hypotension.
Mechanism of Action
PMS Benztropine is an anticholinergic drug, which means it works by blocking the action of acetylcholine. It does this by binding to the acetylcholine receptor, which prevents the neurotransmitter from binding and causing its effects. By reducing the actions of acetylcholine, benzatropine can help to reduce or prevent many of the symptoms associated with conditions like Parkinson’s or anxiety.
How Long Does It Take To Work?
It usually takes about 2 to 4 weeks for benzatropine to take full effect. It is typically taken twice daily, and the effects will become more noticeable as the medication builds up in your system.
Absorption, Route of Elimination, Dosage, Administration
PMS Benztropine is an oral medication that is absorbed into the bloodstream through the stomach and small intestine. It is then metabolized in the liver and excreted through the kidneys. The usual adult dose is 2-4 mg twice a day. A typical starting dose for adults is 1-2 mg twice a day. PMS Benztropine should be taken with food or an antacid to minimize stomach upset.
Side Effect
Common side effects of benzatropine include dry mouth, blurred vision, confusion, restlessness, nausea and vomiting, constipation, and difficulty urinating. More serious side effects, such as seizures, could also occur.
Toxicity
Overdose symptoms of benzatropine include confusion, sedation, agitation, hypotension, seizures, rapid heartbeat, and coma. PMS Benztropine can be toxic in high doses and should not be taken with alcohol or other drugs that can further increase its effects.
Precaution
Patients should not take benzatropine if they are pregnant or breast-feeding. Also, benzatropine should not be taken if you have angle-closure glaucoma, gastrointestinal obstruction, narrow angle glaucoma, myasthenia gravis, or a history of Long QT syndrome.
Interaction
PMS Benztropine may interact with many medications, including some antacids, pain relievers, sedatives, and muscle relaxants. Patients should inform their doctor if they are taking other medications, as some interactions can be serious. Also, benzatropine may interact with alcohol, making its effects stronger.
Disease Interactions
People with the following conditions should use caution when taking benzatropine: osteoporosis, hypertension, seizure disorder, cardiac arrhythmia, urinary tract obstruction, hyperthyroidism, and glaucoma.
Drug Interactions
PMS Benztropine may interact with many other medications that can affect its efficacy or cause serious side effects. It is important to talk to a doctor before taking any other medications while on benzatropine.
Food Interactions
It is recommended to take benzatropine with food or an antacid to minimize stomach upset. Some foods can interact with benzatropine, such as foods high in caffeine and foods containing tyramine (such as aged cheese, cured meats, fish, or fermented soy).
Pregnancy Use
PMS Benztropine should be avoided in pregnant women. There is not enough data to determine the safety of benzatropine in pregnancy.
Lactation Use
It is not known whether benzatropine is excreted in breast milk, so it is not recommended for women who are breast-feeding.
Acute Overdose
If an overdose occurs, call a poison control center immediately. Overdose symptoms include confusion, sedation, agitation, hypotension, seizures, rapid heartbeat, and coma.
Contraindication
People with the following conditions should not take benzatropine: angle-closure glaucoma, gastrointestinal obstruction, narrow angle glaucoma, myasthenia gravis, or a history of Long QT Syndrome.
Use Direction
PMS Benztropine should be taken with food or an antacid to minimize stomach upset. Follow all directions on the prescription label and do not take the medication for longer than prescribed. Do not suddenly stop taking the medication as this can cause withdrawal symptoms.
Storage Condition
Store out of reach of children at room temperature. Do not store in the bathroom. Do not keep medication in a vehicle as temperatures can be too warm or too cold.
Volume of Distribution
PMS Benztropine has an apparent volume of distribution of 81-111 liter/kg.
Half Life
The half-life of benzatropine is approximately 6-9 hours.
Clearance
The average clearance of benzatropine is 0.29-1.58 liters/hour/kg.
Dosage
- Adults: The usual dose is 2-4 mg twice a day.
- Elderly: The starting dose is generally 1-2 mg twice a day.
- Children: The recommended starting dose for children is 0.05-0.2 mg/kg twice a day, not to exceed 6 mg/day.
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