Paramin
Paramin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Paramin is a brand name. Its generic name is Paracetamol + Methionine.
Paramin Introduction
Paramin is a combination medication containing both paracetamol and methane as active ingredients. Paracetamol is a simple analgesic with anti-pyretic properties, while methionine is an amino acid supplement that has been seen to aid with various metabolism related conditions.Uses For Paramin
Paramin is primarily used as a mild painkiller to treat headaches, muscle pain, and other types of minor aches and pains. It may also be used to reduce fever. Additionally, methionine may offer an additional element of metabolism and energy production support.Mechanism of Action
Paramin works by inhibiting the enzyme cyclooxygenase, which in turn blocks the production of inflammatory substances in the body. Methionine helps to support metabolism and energy production, due to its role as an amino acid and its involvement in the urea cycle.How Long Does It Take to Work?
Paramin usually begins to work within about 20 minutes, with peak effect occurring between 1-2 hours post-dose.The effects of certain metnionine may take up to 4 weeks to become fully apparent, due to its gradual accumulation within the body.Absorption
Paramin is absorbed primarily in the small intestine, with peak plasma concentrations being reached within 1-2 hours of administration. Methionine is also absorbed within the small intestine, then metabolized in the Liver and transported to the kidneys for excretion in urine.Route of Elimination
Paramin is primarily eliminated from the body via the kidneys and eliminated through urine. Methionine is also eliminated in part through the urine, and in part via the GI tract as waste.Dosage
The typical dosage for Paramin is 500-1000 mg of paracetamol combined with 500-1000 mg of methionine per administration. It is recommended to take the medication with a full glass of water and with food. For optimal efficacy, take the medication on a regular schedule. Do not crush, chew, or dissolve the tablet, as it may reduce the efficacy of the medication.Administration
Paramin is administered orally. Take the medication with a full glass of water once or twice a day as prescribed. Do not exceed the recommended dose.Side Effects
Paramin may cause some mild side effects, such as nausea, stomach pain, loss of appetite, dizziness, and headache. If these effects become bothersome, consult your doctor or pharmacist.Toxicity
Prolonged use of Paramin may lead to liver toxicity if taken in excessive doses, as excessive doses of paracetamol can cause liver damage or failure. Methionine may cause vomiting, dehydration, and diarrhea at high doses.Precautions
Do not exceed the recommended dose of Paramin. A sufficient amount of water should be consumed while taking this medication. Do not take this medication near bed time as it may cause drowsiness.Interaction
Paramin may interact with certain medications, such as isoniazid, carbamezepine, ethosuximide, and phenytoin. It may also interact with certain supplements and herbal remedies, as well as other vitamins and minerals. It is recommended that you discuss all medications and supplements with your doctor or pharmacist before using Paramin.Disease Interaction
Paramin may interact with certain diseases, such as liver and kidney disease, as this medication may cause further damage to these organs. Patients with asthma, diabetes, and thyroid disorders may also be more sensitive to this medication and should use caution.Drug Interactions
Paramin may interact with certain drugs, such as isoniazid, carbamezepine, ethosuximide, and phenytoin. It may also interact with some supplements and herbal remedies, as well as other vitamins and minerals. It is recommended that you discuss all medications and supplements with your doctor or pharmacist before using Paramin.Food Interactions
Paramin may interact with certain foods, such as those that contain high levels of caffeine. High-fat meals may also interact with this medication and should be avoided.Pregnancy Use
Paramin has been classified as category B by the FDA; however, use of this medication should be avoided during pregnancy unless deemed absolutely necessary by your doctor.Lactation Use
Paramin is not recommended for use in breast-feeding women, as the effects on the infant are not known. It is recommended that you discuss the use of this medication with your doctor if you are a nursing mother.Acute Overdose
In case of an acute overdose of Paramin, seek medical attention immediately. Symptoms of overdose may include nausea, abdominal pain, confusion, dark urine, and sweating.Contraindication
Paramin should not be used in patients with a known hypersensitivity to any of the ingredients in this medication. It should also not be used in patients with impaired renal or hepatic function or in those with active infections.Use Direction
The recommended dosage for Paramin is 500-1000 mg of paracetamol combined with 500-1000 mg of methionine per administration. It is recommended to take the medication with a full glass of water and with food. For optimal efficacy, take the medication on a regular schedule. Do not crush, chew, or dissolve the tablet, as it may reduce the efficacy of the medication.Storage Condition
Paramin should be stored at room temperature, away from light and moisture. Keep out of reach of children and pets.Volume of Distribution
The volume of distribution for Paramin is 0.7L/kg.Half Life
The half-life of Paramin is about 2-3 hours.Clearance
Paramin is eliminated mainly through renal clearance, with a mean clearance of 0.7-1.2L/hr/kg.Here you find in details version of Paramin