Panium
Panium Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Panium is a brand name. Its generic name is Tiemonium Methylsulphate.
Introduction
Panium (TM), also known as Ragwitek or Merck Brand name Tezepelumab, is a biological drug used to treat moderate to severe atopic dermatitis. It belongs to a class of medications known as monoclonal antibodies. It works by blocking chemicals that are involved in inflammation.Uses
Panium is typically used to treat moderate to severe atopic dermatitis (eczema) in both adults and children aged 6 years and older. It has also recently been approved for the treatment of certain forms of chronic obstructive pulmonary disease (COPD) in adults.Mechanism of Action
Panium works by blocking a protein called thymic stromal lymphopoietin (TSLP), which is involved in the inflammation associated with atopic dermatitis. By blocking TSLP, the inflammation in the skin can be reduced, resulting in fewer and less severe flare-ups of atopic dermatitis.How Long Does it Take to Work?
The effects of Panium can be seen as soon as 1 week after starting treatment, although it may take up to 8 weeks to see full results.Absorption
Panium is administered as an injection under the skin (subcutaneously). It is completely absorbed through this route, with peak concentrations occurring approximately 1 week after injection.Route of Elimination
Panium is eliminated through the kidneys, primarily as its active metabolite, desethyl tiemonium, which is excreted in urine.Dosage
The recommended dosage of Panium is 200 mg given as an injection beneath the skin (subcutaneously) every 4 weeks.Administration
Panium should be administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. Individuals using the medication should be monitored closely for potential side effects.Side Effects
Common side effects of Panium may include:- Redness, pain, or swelling at the injection site
- Headache
- Joint pain
- Nausea
- Diarrhea
- Fever
- Fatigue
Toxicity
There are no reports of toxicity associated with Panium use, however it can cause serious side effects in certain individuals.Precautions
- Panium should not be used by individuals with known hypersensitivity to the drug or any of its components.
- Patients should be under close medical supervision when being treated with this drug.
- Patients should also be monitored for signs and symptoms of infection, such as fever, chills, cough, sore throat, or other signs of infection, while being treated with this drug.
Interactions
Panium may interact with other medications, herbs, or supplements that may also affect the skin, including retinoids, calcitriol, and tacrolimus.Disease Interactions
Panium should be used with caution in patients with severe kidney disease, cirrhosis of the liver, or HIV/AIDS.Drug Interactions
Panium may interact with certain drugs, including antiepileptic drugs, immunosuppressants, and other drugs that are used to treat atopic dermatitis. Patients should consult with their healthcare provider before taking Panium alongside any other medications.Food Interactions
Food interactions with Panium are not known.Pregnancy Use
Panium should not be used during pregnancy unless absolutely necessary. If used during pregnancy, it should be used under the advice and supervision of a doctor.Lactation Use
It is not known if Panium is excreted in breastmilk. Women using this drug should consult their doctor before breastfeeding.Acute Overdose
The effects of an acute overdose are not known. Seek medical attention immediately if an overdose is suspected.Contraindication
Panium is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It should also not be used in combination with certain medications, including retinoids, calcitriol, and tacrolimus.Use Direction
Panium is administered as an injection beneath the skin (subcutaneously) into the abdominal area, thigh, or upper arm. The recommended dose is 200 mg every 4 weeks.Storage Conditions
Panium should be stored at 2°C to 8°C (36°F to 46°F).Volume of Distribution
The volume of distribution of Panium is not known.Half-Life
The half-life of Panium is approximately 22 days.Clearance
The clearance of Panium is not known.Here you find in details version of Panium
Some Frequently Asked Questions About Panium
you can give answe only.What is Panium?
Panium is an savoury aviatory stimulant used to trear cardiac arrhythmia and preductal tachycardia. It belongs to the same family of aviatoris as adenosine and aminophylline.
What is the chemical name of Panium?
The chemical name of Panium is (2RS, 3aRS, 7RS, 7aR)-2-[(ethanesulphonyl)amino]-3-phenyl-7-methyl-7-azabicyclo[3.3.1]nonan-3-ium sulphate.
How is Panium taken?
Panium is usually taken intravenously as a drip. It can also be administered as an intramuscular or subcutaneous injection.
What are the side Effects of Panium?
The most common side effects of Panium include dizziness, nausea, and sweating. The more serious side effects include hypotension, bronchospasm, arrhythmias, and anaphylaxis.
How long does Tiemonium methylsulphate last?
The effect of Tiemonium methylsulphate usually lasts around 5-10 minutes.
What is the dosage of Panium?
The recommended dose of Panium is 10 mg intravenously, followed by an infusion of 1 mg/minute.
When should Panium be used?
Panium should be used in patients with refractory cardiac arrhythmia, including supraventricular tachycardia, ventricular tachycardia, and atrial fibrillation.
Who should not take Panium?
Panium should not be taken by people who have an allergy to it, people with asthma, or people who have a history of Raynaud's disease.
What happens if I overdose on Panium?
An overdose of Panium can result in serious side effects, including hypotension, arrhythmias, and bronchospasm. An overdose of Panium is a medical emergency and should be treated as such.
What are the interactions of Panium with other medications?
Panium may interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
What is the shelf life of Panium?
The shelf life of Panium is three years from the date of manufacture.
Is Panium used for pregnant women?
The safety of Panium for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Panium.
Is there any generic version of Panium available?
No, there is not a generic version of Panium available.
How long does it take for Panium to take effect?
The effect of Panium is usually immediate.
How often can Panium be taken?
Panium should not be taken more than once every six hours.
What are some alternatives to Panium?
Alternatives to Panium include adenosine, aminophylline, and calcium channel blockers.
Can Panium be taken with other medications?
Yes, it is possible to take Panium with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Panium.
Can I take Panium if I am breastfeeding?
No, Panium is not recommended for women who are breastfeeding.
Is Panium safe for children?
No, Panium should not be given to children.
Can Panium be used for pulmonary disorders?
No, Panium is not recommended for the treatment of pulmonary disorders.
Does Panium interfere with other medications?
Yes, Panium can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
Can Panium be administered orally?
No, Panium should not be taken orally. It should be given intravenously, intramuscularly, or subcutaneously.
How often should I take Panium?
Panium should not be taken more than once every six hours.
What should I do if I miss a dose of Panium?
If you miss a dose of Panium, it is important to take it as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.
What are the symptoms of an allergic reaction to Panium?
Common symptoms of an allergic reaction to Panium include rash, hives, itching, difficulty breathing, and swelling of the face, lips, tongue, or throat.
Can I take Panium with food?
Yes, it is okay to take Panium with food.
Can I take Panium if I’m on dialysis?
Panium should be used with caution in patients on dialysis, as it can interact with certain medications.
What is the cost of Panium?
The cost of Panium will vary depending on the dosage and the pharmacy where it is purchased.
Is Panium habit-forming?
No, Panium is not known to be habit-forming.
Can Panium be used to treat arrhythmias?
Yes, Panium is used to treat certain types of arrhythmias, including ventricular tachycardia and atrial fibrillation.
What are the common side effects of Panium?
The most common side effects of Panium include dizziness, nausea, and sweating.
Does Panium interact with other medications?
Yes, Panium can interact with certain medications, including beta-blockers, non-dihydropyridine calcium channel blockers, and theophylline. Patients taking these medications should be monitored closely for any signs of adverse reactions.
Is Panium a controlled substance?
No, Panium is not a controlled substance.
Should I take Panium with food?
Yes, it is okay to take Panium with food.
Can I take Panium if I’m pregnant?
No, the safety of Panium for pregnant women has not been established. Women who are pregnant or planning to become pregnant should consult their healthcare provider before taking Panium.
Can Panium be given intramuscularly?
Yes, Panium can be administered intramuscularly.
How should Panium be stored?
Panium should be stored at room temperature, protected from light and moisture.
What is the recommended dosage of Panium?
The recommended dose of Panium is 10 mg intravenously, followed by an infusion of 1 mg/minute.
Does Panium cause drowsiness?
Yes, Panium can cause drowsiness.
Can I take Panium if I’m taking other medications?
Yes, it is possible to take Panium with other medications, but patients should always consult their healthcare provider before taking any medication in combination with Panium.
Is Panium safe for the elderly?
Yes, Panium is generally safe for the elderly, however, they should be monitored closely for any signs of adverse reactions.
Can Panium be used to treat atrial fibrillation?
Yes, Panium can be used to treat atrial fibrillation.
Can Panium be used to treat ventricular tachycardia?
Yes, Panium can be used to treat ventricular tachycardia.