Oxifun

Oxifun Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Oxifun is a brand name. Its generic name is Oxiconazole.

Oxifun Introduction

What is Oxifun?

Oxifun is an antifungal drug used to treat fungal infections. It belongs to the triazole family of drugs that block the growth of fungi.

Uses of Oxifun

Oxifun is used to treat fungal skin infections, including athlete's foot, jock itch, and ringworm. It is also used to treat fungal nail infections.

Mechanism of Action

Oxifun works by stopping the growth of fungal cells. It binds to the fungal cell wall, preventing the production of proteins and DNA that are necessary for the growth of the fungus.

How Long Does it Take to Work?

Oxifun typically takes several days to work. Improvement in symptoms may be seen as early as 1 to 2 days after starting treatment. However, it can take up to 4 weeks for a full response.

Absorption

Oxifun is rapidly absorbed into the bloodstream. Peak concentrations in the blood are reached within 2 to 4 hours after administration.

Route of Elimination

Oxifun is eliminated from the body primarily through the kidneys. About 90% of the drug is eliminated within 24 hours of administration.

Dosage

The dosage of oxiconazole varies depending on the type and severity of the fungal infection and other factors such as age and weight.

Adults

For athlete’s foot, jock itch, and ringworm, the recommended dose is 15 to 25 milligrams daily. For fungal nail infections, the recommended dose is 45 milligrams once weekly.

Children

For athlete’s foot, jock itch, and ringworm, the recommended dose is 15 to 25 milligrams daily. For fungal nail infections, the recommended dose is 45 milligrams every 2 weeks.

Administration

Oxifun should be applied topically to the affected area(s). It is usually recommended that the medicine be applied to clean, dry skin two to three times daily.

Side Effects

The most common side effects of oxiconazole include burning, stinging, redness, and irritation at the application site.

Toxicity

Oxifun is generally considered safe when used as directed. However, overdoses of oxiconazole can be serious and should be treated immediately. Symptoms of an overdose may include nausea, vomiting, and abdominal pain.

Precautions

Oxifun should be used with caution in patients with liver or kidney disease, as well as in patients taking other medications.

Interactions

Oxifun may interact with certain medications, such as warfarin, cyclosporine, and certain antibiotics. It should also not be taken with alcohol.

Disease Interactions

Oxifun should not be used in patients with severe liver or kidney disease, as the drug can cause further damage to the liver and kidneys.

Drug Interactions

Oxifun may interact with certain medications, such as warfarin, cyclosporine, and certain antibiotics. Inform your healthcare provider of all medications you are taking before starting oxiconazole therapy.

Food Interactions

Oxifun does not interact with food or beverages.

Pregnancy Use

Oxifun is classified as pregnancy category C, meaning that it may be harmful to an unborn baby. Consult your doctor before using oxiconazole if you are pregnant.

Lactation Use

Oxifun is not recommended for use during breastfeeding due to the potential for serious adverse reactions in nursing infants.

Acute Overdose

Symptoms of an acute overdose may include nausea, vomiting, and abdominal pain. If you suspect an overdose, contact a healthcare provider immediately.

Contraindication

Oxifun should not be used in patients with severe liver or kidney disease, as the drug can cause further damage to the organ.

Use Direction

Oxifun should be applied topically to the affected area(s). It is usually recommended that the medicine be applied to clean, dry skin two to three times daily.

Storage Condition

Oxifun should be stored at room temperature (15-30° C) in a tightly sealed container away from light and heat.

Volume of Distribution

The volume of distribution for oxiconazole is approximately 65 liters.

Half-Life

The half-life of oxiconazole is approximately 4 to 5 hours.

Clearance

The clearance of oxiconazole is approximately 3.5 liters/hour.

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