Otoderm Tube

Otoderm Tube Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Otoderm Tube is a brand name. Its generic name is Clobetasol Propionate + Ofloxacin + Ornidazole + Terbinafine.

Introduction

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine are a combination drug used to treat superficial fungal and bacterial infections of the skin, including ringworm and athlete’s foot. It is available as a cream, gel, and lotion.

Uses For

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is mainly used to treat infections of the feet caused by fungi or bacteria. It is also used to treat other types of fungal skin infections, including ringworm and other conditions such as contact dermatitis.

Mechanism of Action

Clobetasol Propionate is a synthetic corticosteroid with immunosuppressant and anti-inflammatory effects. It works by blocking the release of certain natural substances that cause inflammation in the body. Ofloxacin is an antibiotic that works by stopping the growth of bacteria. Ornidazole is a synthetic antiprotozoal used to treat infections caused by protozoa such as trichomoniasis, giardiasis, and amebiasis. Terbinafine, an antifungal, works by killing or stopping the growth of fungi that cause infections.

How Long Does It Take to Work?

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination typically takes two to four weeks before the infection is fully cleared up. The duration of treatment depends on the severity of the infection.

Absorption

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is rapidly absorbed through the skin. Peak levels of the drug are reached within 2-4 hours of administration, and the drug is rapidly metabolized and excreted by the body.

Route of Elimination

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is eliminated from the body mainly through the kidneys and feces.

Dosage

The dosage of Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination depends on the severity of the infection and the patient’s age and weight. The dosage for treating fungal skin infections in adults is 0.05% clobetasol propionate, 0.25% ofloxacin, 0.02% ornidazole, and 0.01% terbinafine applied topically twice daily, for up to 4 weeks. For bacterial skin infections, the dosage is 0.05% clobetasol propionate, 0.25% ofloxacin, 0.02% ornidazole applied topically three times daily, for up to 4 weeks.

Administration

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is applied directly to the affected area of the skin, two to three times daily. It should not be applied to the face, underarms, or genitals. The cream should be rubbed in lightly, until it disappears.

Side Effect

The most common side effects of Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination include irritation and burning at the site of application, itching, redness, dryness, and rash.

Toxicity

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is generally considered to be safe. Overdose of the drug may cause benign adverse reactions, however serious or life-threatening toxicities have not been reported.

Precaution

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination should not be used on open wounds, broken skin, or mucous membranes. The drug should also be used with caution in patients with kidney or liver disease, as the drug may be metabolized more slowly in these individuals and lead to higher levels of drug in the body.

Interaction

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination may interact with other drugs such as antacids, NSAIDs, steroids, or other topical medications. It is important to tell the health care provider about all other drugs being taken to avoid drug interactions.

Disease Interaction

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination may be unsafe for patients with certain medical conditions such as diabetes, kidney disease, liver disease, or an immunosuppressed state. It is important to tell the health care provider about any relevant medical conditions before starting treatment.

Drug Interaction

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination may interact with other drugs such as antacids, NSAIDs, steroids, or other topical medications. It is important to tell the health care provider about all other drugs being taken to avoid drug interactions.

Food Interactions

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination may interact with certain foods such as dairy products, which could reduce the absorption of the medication. It is important to tell the health care provider about any relevant dietary restrictions before starting treatment.

Pregnancy Use

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is not recommended for use during pregnancy. The safety of this drug during pregnancy has not been established, therefore it should be used with caution.

Lactation Use

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is not recommended for use during breastfeeding. The safety of this drug during lactation has not been established, therefore it should be used with caution.

Acute Overdose

An acute overdose of Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is unlikely to produce serious symptoms, however symptoms such as increased thirst, headache, nausea, vomiting, dizziness, drowsiness, and/or confusion may occur.

Contraindication

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is contraindicated in patients with a history of hypersensitivity to any of the components of the drug.

Use Direction

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination should be used as directed by a healthcare provider. It should be applied directly to the affected area of the skin twice to three times daily, for up to 4 weeks. It should not be applied to the face, underarms, or genitals.

Storage Condition

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination should be stored at room temperature and away from excessive heat, moisture, and light.

Volume of Distribution

The volume of distribution of Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is not determined.

Half Life

Clobetasol Propionate has an elimination half-life of about 5 hours, while Ofloxacin and Ornidazole have an elimination half-life of about 12 hours. The elimination half-life of Terbinafine is not known.

Clearance

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is cleared from the body mainly through the kidneys and feces.

Here you find in details version of Otoderm Tube

Some Frequently Asked Questions About Otoderm Tube

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Q1. What is Otoderm Tube?

Otoderm Tube is a combination medication used to treat fungal skin infections caused by a particular fungus (dermatophytes).

Q2. How to use Otoderm Tube?

Otoderm Tube should be applied to the affected area of the skin two to three times a day according to instructions given by your doctor.

Q3. What should I avoid while using Otoderm Tube?

It is important to avoid accidental contact with the eyes or nose when using Otoderm Tube. Also, avoid contact with open wounds or skin lesions when using the medication.

Q4. What are the possible side effects of Otoderm Tube?

The possible side effects of Otoderm Tube include itching, burning, irritation and redness. Rarely, more serious reactions such as anaphylaxis and Stevens-Johnson Syndrome may occur.

Q5. How long should I use Otoderm Tube?

You should use Otoderm Tube for as long as directed by your doctor. Usually, the treatment period ranges between two weeks and a month.

Q6. Is Otoderm Tube safe for children?

Otoderm Tube is not recommended for use in children below the age of 12. Talk to a doctor if you are unsure about the suitability of this medication for your child.

Q7. Does Otoderm Tube contain steroids?

Otoderm Tube contains the active ingredient clobetasol propionate, which is a corticosteroid.

Q8. Can Otoderm Tube be used on the face?

Otoderm Tube is generally not recommended for use on the face. Consult a doctor for advice if you need to use the medication on the face.

Q9. Is Otoderm Tube habit-forming?

No, Otoderm Tube is not habit-forming.

Q10. Is Otoderm Tube safe to use during pregnancy?

Otoderm Tube is not recommended for use during pregnancy, as its safety during pregnancy has not been established. If necessary, consult a doctor to decide on the safest alternative.

Q11. How long do I need to wait before I can expect the effects of Otoderm Tube to take effect?

The effects of Otoderm Tube usually take a few days to take effect, depending on the severity of the infection. However, it is important to take the medication for as long as directed by the doctor.

Q12. Is Otoderm Tube safe to use for a long period of time?

Yes, Otoderm Tube can be safely used for a long period of time, as advised by your doctor.

Q13. Can Otoderm Tube cause skin discoloration?

Yes, prolonged use of Otoderm Tube can cause skin discoloration, especially in dark-skinned individuals.

Q14. Is Otoderm Tube a steroid cream?

Yes, Otoderm Tube is a steroid cream.

Q15. How long after applying Otoderm Tube can I wash the affected area?

It is recommended to wait at least 20 minutes after applying Otoderm Tube beforewashing the affected area.

Q16. Is Otoderm Tube suitable for sensitive skin?

Otoderm Tube may cause irritation in people with sensitive skin. It is recommended to use a milder form of this medication if you have sensitive skin.

Q17. What should I do if I experience any side effects while using Otoderm Tube? 

If you experience any side effects while using Otoderm Tube, stop using it and contact your doctor immediately.

Q18. Is Otoderm Tube safe to use during lactation? 

Otoderm Tube is not recommended for use during lactation, as its safety has not been established.

Q19. Can I apply Otoderm Tube before bedtime?

Yes, Otoderm Tube can be applied before bedtime.

Q20. Should I use Otoderm Tube on broken skin?

No, Otoderm Tube should not be used on broken skin.

Q21. Will Otoderm Tube cure my skin infection in one use?

No, Otoderm Tube is not meant to cure your skin infection in one application. You need to use it for the full course as prescribed by your doctor.

Q22. When should I discontinue using Otoderm Tube?

You should discontinue using Otoderm Tube when you no longer have the symptoms of the infection. Continue using it for as long as the doctor has advised.

Q23. Does Otoderm Tube cause skin thinning?

Yes, long-term or overuse of Otoderm Tube can cause skin thinning. If this happens, notify your doctor immediately.

Q24. Is Otoderm Tube available over the counter?

No, Otoderm Tube is not available over the counter. It can only be obtained with a valid prescription from a doctor.

Q25. Does Otoderm Tube cause drowsiness?

No, Otoderm Tube does not cause drowsiness.

Q26. Is it safe to drive after taking Otoderm Tube?

Yes, it is safe to drive after taking Otoderm Tube.

Q27. Should I use Otoderm Tube for treating a fungal nail infection?

No, Otoderm Tube is not suitable for treating a fungal nail infection. Talk to your doctor for the best course of treatment for a fungal nail infection.

Q28. Is Otoderm Tube approved by the FDA?

Yes, Otoderm Tube is approved by the US Food and Drug Administration (FDA).

Q29. Can I use Otoderm Tube for treating a jock itch?

Yes, Otoderm Tube can be used for treating jock itch.

Q30. Does Otoderm Tube have any drug interactions?

Otoderm Tube may interact with some medications such as systemic corticosteroids, cholesterol-lowering drugs, some antiseizure medications, and some HIV medications. Therefore, it is important to inform your doctor about all the medications you are using before taking Otoderm Tube.