Orazid
Orazid Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Orazid is a brand name. Its generic name is Gliclazide.
Introduction
Orazid (also known as glyburide) is an oral anti-diabetic medication used to treat type 2 diabetes. It works by encouraging the release of insulin and lowering the blood sugar levels. It may also be used for other conditions as determined by your doctor.Uses for
Orazid is used to treat type 2 diabetes by helping to lower the blood sugar levels. It is usually prescribed after other diabetes medications have been tried without successful treatment of symptom.Mechanism of Action
Orazid works to treat type 2 diabetes by increasing the effect of insulin, which signals the body to lower the blood sugar level. It can help control glucose levels by increasing the release of insulin and reducing the amount of sugar produced by the liver.How Long Does it Take to Work?
The duration of action of gliclazide is usually 6 to 12 hours, however it can take up to two weeks for it to reach its maximal effect.Absorption
Orazid is rapidly absorbed in the gastrointestinal tract. It is mainly absorbed in the small intestine, with some absorption in the stomach.Route of Elimination
Orazid is eliminated mainly through the kidneys. Approximately 70-90% of it is excreted unchanged in the urine.Dosage
For adults, the recommended starting dose is 30-60mg once daily before the morning meal. The dose can be increased by 30-60mg every 1-2 weeks until the desired blood sugar levels have been achieved. It is important to take the same amount and time of dose each day.Administration
Orazid should be taken as directed by your doctor, usually once daily before a meal. It should be swallowed whole with a glass of water.Side Effect
Orazid can cause side effects such as nausea, vomiting, dizziness, headache, blurred vision, paleness, stomach pain, loss of appetite, diarrhea, lightheadedness, fatigue, and constipation.Toxicity
Orazid is considered to be a low toxicity medication. In case of overdose, symptomatic and supportive treatment should be provided.Precautions
Orazid can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Interaction
Orazid can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Disease Interaction
Orazid may interact with certain diseases and conditions such as liver, kidney, or heart disease; thyroid disorders; and asthma. It is important to tell your doctor about all of your medical conditions before taking gliclazide.Drug Interactions
Orazid may interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Food Interactions
Orazid can interact with certain foods and beverages and increase the risk of side effects. It is important to avoid foods high in sugar and fat while taking gliclazide.Pregnancy Use
Orazid should not be used during pregnancy. Consult your doctor about the potential risks and benefits of taking gliclazide during pregnancy.Lactation Use
It is unknown whether gliclazide is excreted in breast milk. It is recommended to avoid taking gliclazide while breastfeeding.Acute Overdose
In case of an acute overdose of gliclazide, symptomatic and supportive treatment should be provided.Contraindication
Orazid should not be used in patients with diabetic ketoacidosis, type 1 diabetes, type 3 diabetes, and in those allergic to it.Use Direction
Orazid should be taken exactly as prescribed by your doctor. Do not increase or decrease the dose, or take the medication for a longer period of time than prescribed.Storage Conditions
Orazid should be stored at room temperature, away from direct sunlight, heat and moisture. It should be kept out of the reach of children and pets.Volume of Distribution
The volume of distribution of gliclazide is approximately 20-50 L/kg.Half life
The elimination half-life of gliclazide is 1.5-4.5 hours.Clearance
The clearance of gliclazide in adults is 0.15-0.3 ml/min/kg.Here you find in details version of Orazid
Some Frequently Asked Questions About Orazid
What is Orazid?
Orazid is a medication which belongs to the group of medicines called sulfonylureas. It is used to control blood glucose levels in people with type 2 diabetes.
How does Orazid work?
Orazid works by increasing the amount of insulin that is released by the pancreas which helps to control blood glucose levels in people with Type 2 diabetes.
What are the uses of Orazid?
Orazid is used to control blood glucose levels in people with Type 2 diabetes.
What are the side effects of Orazid?
Orazid may cause some side effects, including headache, nausea, weight gain, tiredness, and some skin rashes.
Does Orazid cause hypoglycemia?
Yes, Orazid can cause hypoglycemia, which is a condition where the blood glucose levels become too low. Symptoms of hypoglycemia include sweating, hunger, shakiness, dizziness, and confusion.
How should Orazid be taken?
Orazid should be taken orally usually once or twice a day as directed by your doctor.
How long does it take for Orazid to work?
Orazid usually starts to work within 1-2 hours after it is taken.
Does Orazid need to be taken with food?
No, Orazid does not need to be taken with food. It can be taken before, with, or after meals.
What is the recommended dose of Orazid?
The recommended dose of Orazid depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.
What should I do if I forget to take Orazid?
If you forget to take Orazid, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.
Should I avoid alcohol while taking Orazid?
Yes, it is recommended to avoid alcohol while taking Orazid as it can increase the risk of adverse effects such as low blood sugar.
Can Orazid be taken while pregnant or breastfeeding?
Orazid should not be taken while pregnant or breastfeeding. Speak to your doctor before taking any medication while pregnant or breastfeeding.
What foods should I avoid while taking Orazid?
It is important to follow a healthy and balanced diet while taking Orazid. Avoid foods high in sugar, fat, and cholesterol.
Is Orazid available as a generic medication?
Yes, Orazid is available as a generic medication.
What other medications should not be taken with Orazid?
Certain medications can interact with Orazid and should not be taken together. This includes ACE inhibitors, diuretics, sulfonamides, cimetidine, and other sulfonylureas.
Can I take Orazid with metformin?
Yes, Orazid can be taken with metformin. It is important to take both medications as prescribed by your doctor.
Are there any alternatives to Orazid?
Yes, there are other medications available to control blood glucose levels. Speak to your doctor or pharmacist about other alternatives.
Can Orazid be used to treat type 1 diabetes?
No, Orazid is not suitable for use in people with type 1 diabetes.
Does Orazid cause weight gain?
Orazid can cause weight gain in some cases. It is important to follow a healthy and balanced diet and to exercise regularly.
What should I do if I experience side effects while taking Orazid?
If you experience side effects while taking Orazid, speak to your doctor or pharmacist. They may be able to suggest a change in dosage or medication to help alleviate the side effects.
Can diabetic ketoacidosis occur while taking Orazid?
Yes, diabetic ketoacidosis can occur while taking Orazid. Symptoms include dry mouth, thirst, fatigue, fruity odor on breath, and rapid breathing.
How should Orazid be stored?
Orazid should be stored at room temperature away from direct sunlight and heat. Do not keep Orazid in the refrigerator or freezer.
Can I overdose on Orazid?
Yes, it is possible to overdose on Orazid. If you or someone you know has taken an overdose, call your local poison control center or emergency services immediately.
Can I donate blood while taking Orazid?
No, it is recommended that you do not donate blood while taking Orazid.
Can I take Orazid if I have kidney disease?
It is recommended that you speak to your doctor before taking Orazid if you have kidney disease. Your doctor may recommend a different medication.
Is Orazid a blood thinner?
No, Orazid is not a blood thinner. It is used to control blood glucose levels in people with Type 2 diabetes.
Can Orazid be used to treat Type 1 diabetes?
No, Orazid is not suitable for use in people with Type 1 diabetes.
Can Orazid cause low blood pressure?
Yes, Orazid can cause low blood pressure, which can cause dizziness, lightheadedness, and fainting.
Can I take Orazid while taking other medications?
It is important to let your doctor know about all medications that you are taking before taking Orazid. Certain medications can interact with Orazid.
Does Orazid raise cholesterol levels?
Yes, Orazid can raise cholesterol levels. It is important to follow a healthy and balanced diet to help maintain healthy cholesterol levels.
Is Orazid a steroid?
No, Orazid is not a steroid. It is used to control blood glucose levels in people with Type 2 diabetes.
Does Orazid cause diarrhea?
Yes, Orazid can cause diarrhea. If you experience diarrhea while taking Orazid, speak to your doctor or pharmacist.
Can I take Orazid with ibuprofen?
It is recommended that you do not take Orazid with ibuprofen as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.
Can I take Orazid with muscle relaxers?
It is recommended that you do not take Orazid with muscle relaxers as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.
What should I do if I miss a dose of Orazid?
If you miss a dose of Orazid, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.
Can I take Orazid while breastfeeding?
No, it is recommended that you do not take Orazid while breastfeeding. Speak to your doctor before taking any medications while breastfeeding.
Can I take Orazid while pregnant?
No, it is recommended that you do not take Orazid while pregnant. Speak to your doctor before taking any medications while pregnant.
Can Orazid cause headaches?
Yes, Orazid can cause headaches in some people. If you experience headaches while taking Orazid, speak to your doctor or pharmacist.
Can I take Orazid with other diabetes medications?
Yes, Orazid can be taken with other diabetes medications. It is important to follow the instructions of your doctor or pharmacist.
What should I do if I experience low blood sugar while taking Orazid?
If you experience low blood sugar while taking Orazid, it is important to eat or drink something sugary, such as fruit juice, honey, candy, or a glucose tablet. It is also important to speak to your doctor or pharmacist.
Are there any foods that I should avoid while taking Orazid?
It is important to follow a healthy and balanced diet while taking Orazid. Avoid foods high in sugar, fat, and cholesterol.
How long can I take Orazid for?
The length of time that you take Orazid for depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.
Is Orazid a controlled substance?
No, Orazid is not a controlled substance.