Oramet SR

Oramet SR Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Oramet SR is a brand name. Its generic name is Metformin.

Oramet SR

Oramet SR is a medication used to treat type 2 diabetes mellitus (T2DM). It works by lowering the amount of sugar produced by the liver and preventing cells from absorbing sugar in the bloodstream. Oramet SR also increases insulin sensitivity in the body.

Uses For Oramet SR

Oramet SR is used to treat type 2 diabetes mellitus by helping the body to regulate blood sugar levels and reduce the amount of glucose produced by the liver. It can also help prevent the risk of developing complications from diabetes, such as stroke, heart attack, and kidney failure.

Mechanism of Action

Oramet SR works mainly by inhibiting the production of glucose in the liver and increasing the sensitivity of peripheral tissues to the action of insulin. The drug also reduces the absorption of glucose in the small intestine, leading to an overall decrease in circulating glucose levels.

How Long Does It Take to Work?

The effects of metformin can be felt within one week of starting the drug. After four weeks, the desired benefits should start to be noticed. However, it may take up to three months to reach the full effect of the drug.

Absorption

Oramet SR is absorbed quickly from the gastrointestinal tract. Peak plasma levels are usually seen within 2-4 hours after oral administration.

Route of Elimination

Oramet SR is primarily excreted via the urinary system, with approximately 50% to 75% of the drug being eliminated in the urine as unchanged metformin.

Dosage

Oramet SR is available as an oral tablet or liquid solution in dosages ranging from 500mg to 2000mg. The typical starting dose is 500mg twice a day orally with meals. The maximum daily dose is usually 2000mg per day.

Administration

Oramet SR is typically taken by mouth with food twice a day. The tablets should be swallowed whole and not crushed or chewed. The liquid form of the drug should be taken with meals as well, preferably in divided doses.

Side Effects

Common side effects of metformin include abdominal pain, diarrhoea, nausea, vomiting, and metallic taste. Rare but serious side effects include lactic acidosis and hypoglycemia.

Toxicity

Oramet SR is well tolerated and has a low rate of toxicity. If taken at prescribed doses, it can be safely used for a long period of time.

Precaution

Patients with renal, hepatic, or heart disease should consult their doctor before taking metformin. Patients should also inform their doctor if they have any history of alcohol abuse or liver disease.

Interactions

Patients should inform their doctor of all medications and supplements they are taking before taking metformin. This is to ensure that there are no drug interactions or adverse reactions.

Disease Interactions

Oramet SR can alter the effects of certain medications and can increase the risk of adverse reactions in patients with liver, kidney, or heart disease.

Drug Interactions

Oramet SR interacts with many medications, including some common and over the counter products. Patients should always inform their doctor of any other medications they are taking before taking metformin.

Food Interactions

Certain foods may interact with metformin, such as certain antacids, mineral or calcium supplements, alcohol, or grapefruit juice. Patients should always consult their doctor or pharmacist before adding any dietary supplements to their regimen.

Pregnancy Use

Oramet SR is not recommended for pregnant women. If a woman becomes pregnant while taking metformin, she should stop taking the medication and talk to her doctor about alternative options.

Lactation Use

Oramet SR is not recommended for use in lactating mothers due to the potential for adverse effects to the baby.

Acute Overdose

An acute overdose of metformin can be dangerous and life-threatening. Symptoms of an overdose include vomiting, confusion, and lactic acidosis. Treatment includes supportive care and administration of folic acid or insulin.

Contraindications

Oramet SR is contraindicated in patients with hypoglycemia, kidney disease, and heart failure. It should also be avoided in patients with a history of alcoholic liver disease.

Use Direction

Oramet SR should be taken with food twice a day at evenly spaced intervals. Patients should take the dose that is prescribed by their doctor and should only take the prescribed amount. They should also avoid taking higher doses than prescribed.

Storage Condition

Oramet SR should be stored at room temperature away from heat, moisture, and direct sunlight. It should also be stored away from children and pets.

Volume of Distribution

The volume of distribution of Oramet SR is approximately 17–22 L/kg.

Half Life

The half-life of Oramet SR is approximately 4–6 hours.

Clearance

Oramet SR is cleared from the body primarily by the kidneys. The clearance of Oramet SR is approximately 5–10 L/h/kg.

Here you find in details version of Oramet SR

Some Frequently Asked Questions About Oramet SR

What is Oramet SR?

Oramet SR is an oral diabetes medicine that helps control blood sugar levels. It is used to treat people with type 2 diabetes.

How does Oramet SR work?

Oramet SR helps control blood sugar levels by reducing the amount of glucose produced by the liver and by making it easier for the body to absorb glucose from the food you eat.

What are the benefits of taking Oramet SR?

Oramet SR can help control your blood sugar levels, lower the risk of long-term complications of diabetes, and reduce the risk for heart attack and stroke.

What are the side effects of Oramet SR?

The most common side effects of Oramet SR are nausea, diarrhea, bloating, and indigestion. More serious side effects include lactic acidosis, a rare but potentially life-threatening condition.

Who should not take Oramet SR?

Oramet SR should not be taken by people with advanced kidney disease, disabled patients, pregnant women, and those with certain types of allergies.

Should I take Oramet SR with meals?

It is recommended to take Oramet SR with meals. This may help reduce the risk of side effects such as stomach upset or diarrhea.

How long does it take Oramet SR to work?

Oramet SR usually starts working within 1–2 weeks of taking it, but it may take up to 3 months to reach its full effectiveness.

How should I store Oramet SR?

Oramet SR should be stored at room temperature, away from light and moisture. The tablets should be kept in their original container and away from children.

What should I do if I miss a dose of Oramet SR?

If you miss a dose of Oramet SR, take it as soon as you remember. Do not take more than one dose to make up for a missed dose.

Can Oramet SR cause weight gain?

No, Oramet SR has been shown to cause weight loss in some people. However, it is possible that Oramet SR may cause weight gain in some people.

Can I drink alcohol while taking Oramet SR?

It is generally not recommended to drink alcohol while taking Oramet SR. Alcohol can increase the risk of lactic acidosis, a serious side effect of Oramet SR.

If I experience any side effects while taking Oramet SR, what should I do?

If you experience any side effects while taking Oramet SR, stop taking it immediately and contact your doctor. They may be able to advise you of other medications or treatments that may be suitable for you.

Can I take Oramet SR if I'm pregnant?

Oramet SR is not recommended for use during pregnancy. If you are pregnant, or plan to become pregnant, you should talk to your doctor about other treatments that are safe for you.

Can I take Oramet SR if I'm breastfeeding?

Oramet SR has not been studied in women who are breastfeeding. It is important to talk to your doctor if you are breastfeeding, pregnant, or plan to become pregnant to determine the best treatment plan for you.

Is Oramet SR a generic drug?

Yes, Oramet SR is a generic drug. It is available in the form of tablets and extended-release tablets.

Can I take Oramet SR if I have other medical conditions?

It is important to talk to your doctor before taking Oramet SR if you have any other medical conditions, such as kidney or liver problems, or if you are taking other medications.

What other medications can interact with Oramet SR?

Oramet SR may interact with certain other medications, including insulin, nonsteroidal anti-inflammatory drugs (NSAIDs), phenothiazines, sulfonamides, and certain antibiotics. Talk to your doctor before taking Oramet SR with any other medications.

Is Oramet SR covered by insurance?

Most insurance plans will cover Oramet SR, although cost may vary depending on your plan and your location. It is best to contact your insurance provider directly to find out what is covered and what your deductible may be.

Can I get Oramet SR over-the-counter?

No, Oramet SR is a prescription medication and is not available over-the-counter.

What dosages of Oramet SR are available?

Oramet SR is available in a variety of dosages including 500mg, 850mg, and 1000mg tablets, as well as extended-release tablets in 500mg and 1000mg dosages.

Is Oramet SR safe?

Yes, Oramet SR is generally safe when taken as directed by your doctor. However, some people may experience side effects and it is important to talk to your doctor if you experience any.

Can Oramet SR cause kidney damage?

Oramet SR may cause an adverse reaction in some people that can lead to kidney damage. It is important to talk to your doctor if you have any concerns or experience any side effects.

Do I need to take Oramet SR with food?

It is recommended to take Oramet SR with food. This may help reduce the risk of side effects such as nausea, diarrhea, bloating, and indigestion.

What is the difference between Oramet SR and Oramet SR ER?

Oramet SR and Oramet SR ER (extended-release) are both forms of the same medication. Oramet SR ER is designed to slowly release the medication in the body over a long period of time, usually 8-12 hours.

What should I do if I experience side effects from Oramet SR?

If you experience any side effects while taking Oramet SR, stop taking it immediately and contact your doctor. They can advise you of other medications or treatments that may be suitable for you.

How much Oramet SR should I take?

The amount of Oramet SR you should take will depend on your doctor's instructions, as well as your age, weight, and other health factors. Do not change your dose without talking to your doctor first.

Can I take Oramet SR if I have low blood sugar?

No, Oramet SR should not be taken if you have low blood sugar (hypoglycemia). If you have low blood sugar, it is important to treat it with food or a diabetes-related medicine, such as insulin.

Does Oramet SR lower blood sugar?

Yes, Oramet SR can help lower blood sugar levels. This is done by reducing the amount of glucose produced by the liver and by making it easier for the body to absorb glucose from food.

What time of the day should I take Oramet SR?

It is best to take Oramet SR at the same time each day as directed by your doctor. For Oramet SR ER, it is best to take it just before you go to bed.

Can I take Oramet SR to lose weight?

Oramet SR is not generally prescribed for weight loss. However, some patients may experience weight loss as a side effect. It is important to talk to your doctor before taking Oramet SR for any purpose other than treating diabetes.

Can Oramet SR cause headaches?

Headache is a possible side effect of Oramet SR. If you experience a headache while taking Oramet SR, contact your doctor. They may be able to advise you of other medications or treatments that may be suitable for you.

Can I take Oramet SR with vitamins or supplements?

It is generally not recommended to take Oramet SR with vitamins or supplements. Talk to your doctor before taking Oramet SR with any other medications or supplements.

Is Oramet SR a blood thinner?

No, Oramet SR is not a blood thinner. It is an oral diabetes medicine that helps control blood sugar levels.

Does Oramet SR interact with other drugs?

Yes, Oramet SR can interact with certain drugs, including insulin, nonsteroidal anti-inflammatory drugs (NSAIDs), phenothiazines, sulfonamides, and certain antibiotics. Talk to your doctor before taking Oramet SR with any other medications.

Should I take Oramet SR with food or on an empty stomach?

It is recommended to take Oramet SR with food. This may help reduce the risk of side effects such as stomach upset or diarrhea.

How will Oramet SR affect my blood sugar levels?

Oramet SR can help lower your blood sugar levels in several ways. It reduces the amount of glucose produced by the liver and makes it easier for the body to absorb glucose from food. It also increases sensitivity to insulin, which helps your body use glucose more efficiently.

Can Oramet SR help with PCOS?

Yes, Oramet SR can help manage symptoms of polycystic ovary syndrome (PCOS). Studies have shown that Oramet SR can help improve insulin sensitivity, reduce hormonal levels, and reduce the risk of developing type 2 diabetes in women with PCOS.

Is Oramet SR safe for elderly patients?

Yes, Oramet SR is generally safe for elderly patients, however, it is important to talk to your doctor about any other health issues or medications that you may be taking as these may interact with Oramet SR.

What is the recommended dosage of Oramet SR?

The recommended dosage of Oramet SR will depend on your age, weight, and other health factors. It is important to follow your doctor's instructions and do not change your dose without talking to your doctor first.