Omesoft
Omesoft Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Omesoft is a brand name. Its generic name is Omega-3 Acid Ethyl Esters.
Omesoft
Omesoft (O3EEs) are containing fatty acids, primarily eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) extracted from fish oil. It is used to reduce the serum total and low-density lipoprotein cholesterol (LDL-C) levels, triglyceride optimization, and in the treatment of hypertension.
Uses For
Omesoft are used for the treatment of high triglycerides (hypertriglyceridemia) in adults and to reduce the risk of coronary heart disease (CHD). It can also be used to reduce the risk of myocardial infarction and stroke, to reduce other coronary risk factors, and to reduce the risk of death from coronary heart disease.
Mechanism of Action
Omesoft interfere with the synthesis and activity of lipoproteins involved in the reverse-transport of cholesterol from peripheral tissues to the liver. By binding to the membrane of cultured endothelial cells, it modulates and reduces levels of various inflammatory mediators in the blood. In addition, O3EEs inhibit the production of very low-density lipoproteins (VLDL), reduce the activity of fatty acid synthesis enzyme and reduce the size of both LDL and VLDL particles.
How Long Does it Take To Work
It usually takes about 4 to 8 weeks to benefit from the effects of Omesoft. However, some patients may experience a response sooner or later than this.
Absorption
Omesoft are absorbed from the gastrointestinal tract. After being incorporated into plasma phospholipids, EPA and DHA are found in red blood cells and other tissues.
Route of Elimination
Omesoft are mainly eliminated in bile, with the majority of it being converted to ethyl arachidonate and other metabolites that are then excreted in the feces.
Dosage
Omesoft should be taken as directed by a qualified health professional. The suggested dosage for adults is 1 to 4 g daily in 2 to 4 divided doses with meals.
Administration
Omesoft should be taken orally with meals or as directed by a qualified health professional. It can be taken with or without food.
Side Effects
Omesoft may cause side effects including gastrointestinal upset, hypotension, bleeding, and altered platelet function.
Toxicity
The toxic effects of Omesoft are largely unknown. The most common side effect is gastrointestinal upset.
Precaution
Patients with impaired renal function, hypotension, or bleeding disorders should use caution when taking Omesoft. Patients should not take Omesoft if they are using other medications that affect platelet function or have any other known allergies or medical problems.
Interaction
Omesoft may interact with other medications, especially those that affect platelet function. Patients should discuss all medications taken with their doctor before taking Omesoft.
Disease Interaction
Omesoft may be beneficial to patients with coronary heart disease, hypertension, or hyperlipidemia. Patients with decreased renal function, hypotension, or bleeding disorders should use caution when taking Omesoft.
Drug Interaction
Omesoft may interact with other medications, especially those that affect platelet function. These include aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), warfarin (Coumadin), and other anticoagulants. Patients should discuss all medications taken with their doctor before taking Omesoft.
Food Interactions
It is recommended to take Omesoft with food to increase absorption. There are no known food interactions.
Pregnancy Use
Omesoft should be used with caution during pregnancy. Consult with a doctor before using O3EEs during pregnancy.
Lactation Use
It is not known if O3EEs are safe to use during lactation. Consult with a doctor before using O3EEs while breastfeeding.
Acute Overdose
No data is available on the effects of an acute overdose of Omesoft. Seek medical attention if an overdose is suspected.
Contraindication
Patients should not take Omesoft if they are using other medications that affect platelet function or have any other known allergies or medical problems.
Use Instructions
Patients should take Omesoft as directed or as prescribed by their doctor. Take this medication with meals or as directed by a qualified health professional. Do not take more or less than recommended.
Storage Condition
Omesoft should be stored in a cool, dry place, away from excessive heat, light, and moisture. Keep it out of the reach of children and pets.
Volume of Distribution
The volume of distribution for Omesoft is unknown.
Half Life
The half-life of Omesoft is unknown.
Clearance
The clearance of Omesoft is unknown.
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