Notensil

Notensil Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Notensil is a brand name. Its generic name is Gabapentin.

Introduction

Notensil is a white to off-white crystalline solid with a pK a1 of 3.7 and a pK a2 of 11. It's structural formula is: C9H17NO2•HCl

Uses For

Notensil is used to treat partial seizures, post-herpetic neuralgia, and neuropathic pain associated with diabetic peripheral neuropathy.

Mechanism of Action

Notensil binds to calcium channels located in the central nervous system. This action results in a reduction of the release of several neurotransmitters, including glutamate, substance P, and calcitonin gene-related peptide, which are important for controlling seizures and pain perception.

How Long Does It Take to Work?

The effects of gabapentin can begin to occur within a few hours of first taking the medication. In some cases, it may take up to two weeks for the full effects to be felt.

Absorption

Notensil is rapidly absorbed after oral administration, with peak plasma concentrations occurring within 1.5-2 hours.

Route of Elimination

Notensil is primarily eliminated via renal excretion and is eliminated in urine as unchanged drug.

Dosage

The recommended starting dosage of gabapentin is:

• For partial seizures in adults and adolescents aged 12 and older: 300mg orally three times a day for the first week; the dosage can then be increased up to a maximum of 2400mg/day.
• For post-herpetic neuralgia in adults and adolescents aged 12 and older: the starting dosage is 300mg orally, three times a day; the dosage can then be increased up to a maximum of 2400mg/day.
• For neuropathic pain associated with diabetic peripheral neuropathy in adults and adolescents aged 12 and older: the starting dosage is 300mg orally, followed by an escalation to 1800mg/day.

Administration

Notensil should be taken orally with or without food as prescribed by your doctor.

Side Effect

Common side effects of gabapentin include fatigue, dizziness, drowsiness, headache, nausea, blurred vision, dry mouth or changes in taste, constipation, nervousness, unsteadiness, insomnia, and weight gain.

Toxicity

Notensil is generally safe and well tolerated, however excessive doses may lead to acute toxicity. Symptoms of toxicity include confusion, disorientation, irregular heart rate, low blood pressure, and respiratory depression.

Precautions

Before taking gabapentin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Interaction

Notensil may interact with other drugs and supplements. It is important to tell your doctor or pharmacist about all drugs and supplements you are taking, as they could affect how gabapentin works. These drugs include, but are not limited to: antacids, opioids, certain antibiotics, antifungals, anticonvulsants, MAO inhibitors, narcotics, or certain calcium channel blockers.

Disease Interaction

Using gabapentin in combination with other drugs that affect central nervous system activity may increase the risk of serious side effects. These drugs include, but are not limited to: cold or allergy medicines, narcotic pain medicines, sleeping pills, muscle relaxers, and medicines for seizures, depression, or anxiety.

Drug Interaction

Drug interactions may affect how gabapentin works in your body, and could increase your risk of serious side effects. These interactions include, but are not limited to: certain antibiotics, antifungals, anticonvulsants, MAO inhibitors, narcotics, or certain calcium channel blockers. Be sure to tell your doctor or pharmacist about all drugs and supplements you are taking.

Food Interactions

Eating certain foods can increase the absorption of gabapentin, thus increasing the level of the drug in your body, which in turn can increase the risk of serious side effects. Therefore, it is important to avoid foods high in fat or cholesterol when taking this medication.

Pregnancy Use

Notensil should not be used during pregnancy unless the benefit outweighs the risk. If you become pregnant while taking gabapentin, it is important to talk to your doctor about the potential risks.

Lactation Use

It is not known if gabapentin is excreted into human milk. Because of this, it is recommended that if you are breastfeeding, you should not use gabapentin.

Acute Overdose

Symptoms of an acute overdose may include confusion, disorientation, irregular heart rate, low blood pressure, and respiratory depression.

Contraindication

Notensil is contraindicated in patients who have known hypersensitivity to the drug. It should also be avoided in patients with a history of renal insufficiency, as gabapentin is primarily eliminated via renal excretion.

Use Direction

Take gabapentin exactly as prescribed by your doctor. Do not take more or less than what is recommended. Taking too much gabapentin can cause serious side effects. If you are taking any other medications or supplements, talk to your doctor before using gabapentin.

Storage Condition

Notensil should be stored in a dry, cool place away from direct sunlight at room temperature. Keep it in a tightly closed container.

Volume of Distribution

The volume of distribution is 0.85-1.9 L/kg.

Half Life

The half life of gabapentin is 5-7 hours.

Clearance

The clearance of gabapentin is 210-310 ml/min.

Here you find in details version of Notensil

Some Frequently Asked Questions About Notensil

What is Notensil?

Notensil is an anti-epileptic medication, also called an anticonvulsant. It is used to treat certain types of seizures and is also used to treat nerve pain associated with various conditions, such as postherpetic neuralgia.

What is Notensil used for?

Notensil is used to control partial seizures in adults with epilepsy. It is also used to treat certain types of nerve pain and to treat restless legs syndrome.

How long does it take for Notensil to work?

The effects of Notensil may be seen within 2-3 days. As with any medication, individual response will vary.

How fast does Notensil work?

The effects of Notensil usually occur quite rapidly, but as with any medication, individual response will vary.

What are the side effects of Notensil?

The most common side effects of Notensil are drowsiness, dizziness, and headache. Other side effects may include swelling, confusion, depression, and difficulty breathing.

Can Notensil cause anxiety?

Yes, Notensil can cause anxiety. If you are experiencing anxiety after taking Notensil, it is important to talk to your doctor about the possibility of side effects.

Can you take Notensil with alcohol?

It is not recommended to take Notensil with alcohol. Combining Notensil with alcohol may increase the risk of side effects such as drowsiness. It is best to avoid drinking alcohol while taking Notensil.

Can you take Notensil with other medications?

Yes, Notensil can be taken with other medications. However, it is important to tell your doctor about all the medications, supplements, and vitamins you are taking to avoid possible interactions. Always check with your doctor before taking Notensil with other medications.

Is Notensil a narcotic?

No, Notensil is not a narcotic. It is an anti-epileptic medication, also called an anticonvulsant.

How long does Notensil stay in your system?

Notensil can stay in your system for up to 72 hours after your last dose. However, this time frame can vary depending on several factors, including your age, kidney function, and metabolism.

Is Notensil an opioid?

No, Notensil is not an opioid. It is an anti-epileptic medication, also called an anticonvulsant.

Can I take Notensil while pregnant?

It is not recommended to take Notensil while pregnant. Talk to your doctor about the risks and benefits of taking Notensil during pregnancy.

Can I take Notensil while breastfeeding?

It is not recommended to take Notensil while breastfeeding. Talk to your doctor about the risks and benefits of taking Notensil while breastfeeding.

Can Notensil help with nerve pain?

Yes, Notensil can be used to treat nerve pain. It is commonly used to treat postherpetic neuralgia, a common complication of shingles.

Does Notensil cause weight gain?

Yes, weight gain is a possible side effect of Notensil. If you are experiencing weight gain while taking Notensil, it is important to talk to your doctor about the possibility of adjusting the dosage.

Can you overdose on Notensil?

Yes, it is possible to overdose on Notensil. Taking too much Notensil can cause symptoms such as confusion, drowsiness, and slowed breathing. If you think you have overdosed on Notensil, it is important to seek medical attention immediately.

Is Notensil effective for treating seizures?

Yes, Notensil is effective for treating certain types of seizures. It is used to control partial seizures in adults with epilepsy.

What are the long-term effects of Notensil?

The long-term effects of Notensil are largely unknown. Common side effects may include increased fatigue, changes in behavior, and dizziness. Rare side effects may include severe allergic reactions and serotonin syndrome.

Can Notensil cause hair loss?

Yes, hair loss is a possible side effect of Notensil. If you are experiencing hair loss while taking Notensil, it is important to talk to your doctor about the possibility of adjusting the dosage.

Can I take ibuprofen with Notensil?

Yes, ibuprofen can be taken with Notensil. However, it is important to talk to your doctor before taking any medications together.

Does Notensil cause hallucinations?

Yes, hallucinations are a possible side effect of Notensil. If you experience hallucinations after taking Notensil, it is important to talk to your doctor about the possibility of adjusting the dosage.

Does Notensil affect blood pressure?

Yes, Notensil may affect blood pressure. Taking Notensil may increase the risk of low blood pressure, which can cause dizziness and light-headedness.

Can I take Tylenol with Notensil?

Yes, Tylenol can be taken with Notensil. However, it is important to talk to your doctor before taking any medications together.

Is Notensil habit forming?

No, Notensil is not a habit forming medication. However, if you feel like you need to take higher doses then you should talk to your doctor about the possibility of adjusting the dosage.

Does Notensil help with anxiety?

Yes, Notensil can help with anxiety. It is used to treat certain types of anxiety disorders. However, it is important to talk to your doctor before starting Notensil to treat anxiety.

Does Notensil help with sleep?

Yes, Notensil can help with sleep. It is used to treat certain types of sleep disorders, such as insomnia and restless legs syndrome.

Can I take Notensil with Xanax?

Yes, Notensil can be taken with Xanax. However, it is important to talk to your doctor before taking any medications together.

Can I take Notensil with Wellbutrin?

Yes, Notensil can be taken with Wellbutrin. However, it is important to talk to your doctor before taking any medications together.

Can I take Notensil with Prozac?

Yes, Notensil can be taken with Prozac. However, it is important to talk to your doctor before taking any medications together.

Can Notensil cause liver damage?

Yes, liver damage is a possible side effect of Notensil. If you experience any signs or symptoms of liver damage after taking Notensil, it is important to talk to your doctor about the possibility of adjusting the dosage.

Does Notensil help with nerve pain?

Yes, Notensil can help with nerve pain. It is commonly used to treat postherpetic neuralgia, a common complication of shingles.

Does Notensil cause constipation?

Yes, constipation is a possible side effect of Notensil. If you experience constipation while taking Notensil, it is important to talk to your doctor about the possibility of adjusting the dosage.

Can Notensil cause dizziness?

Yes, dizziness is a possible side effect of Notensil. If you experience dizziness after taking Notensil, it is important to talk to your doctor about the possibility of adjusting the dosage.

Is Notensil an anti-inflammatory?

No, Notensil is not an anti-inflammatory. It is an anti-epileptic medication, also called an anticonvulsant.

Can I take Notensil with Ativan?

Yes, Notensil can be taken with Ativan. However, it is important to talk to your doctor before taking any medications together.

Can I take Notensil with Flexeril?

Yes, Notensil can be taken with Flexeril. However, it is important to talk to your doctor before taking any medications together.

Can I take Notensil with Tramadol?

Yes, Notensil can be taken with Tramadol. However, it is important to talk to your doctor before taking any medications together.

Does Notensil help with depression?

Yes, Notensil can help with depression. It is used to treat certain types of depression and has been shown to be effective in reducing symptoms of depression.

Does Notensil help with withdrawal symptoms?

Yes, Notensil can help with withdrawal symptoms. It is commonly used to treat drug and alcohol withdrawal, as well as nicotine withdrawal.

Can I take Notensil with Ambien?

Yes, Notensil can be taken with Ambien. However, it is important to talk to your doctor before taking any medications together.

Can I take Notensil with Zoloft?

Yes, Notensil can be taken with Zoloft. However, it is important to talk to your doctor before taking any medications together.

What is the maximum dosage of Notensil?

The maximum dosage of Notensil is 1800 mg per day. However, it is important to talk to your doctor to determine the best dosage for you.