Nasowikoryl
Nasowikoryl Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Nasowikoryl is a brand name. Its generic name is Xylometazoline.
Nasowikoryl Introduction
Nasowikoryl is a nasal decongestant drug of the imidazoline family. This medication is used to temporarily relive nasal congestion (stuffy nose) due to colds, flu, hay fever, allergies, and other breathing illnesses. Nasowikoryl is sometimes prescribed off-label to treat nasal polyps. It is also available in combination with other active ingredients in some products.
Uses for Nasowikoryl
Nasowikoryl is used to temporarily relive nasal congestion (stuffy nose) due to colds, flu, hay fever, allergies, and other breathing illnesses. It is also used to treat nasal polyps, off-label. It sometimes comes as a combination drug with other active ingredients in some products.
Mechanism of Action
Nasowikoryl works by stimulating alpha-adrenergic receptors located in the smooth muscles on the nasal mucosa, which produces a sympathomimetic effect of narrowing the vessels, leading to reduced nasal congestion. This reduction in swelling helps to open the nasal passages and clear the congestion.
How Long Does It Take To Work?
Nasowikoryl typically has a fast onset of action, usually within 15 minutes. Its duration of effect is usually around 12 hours, but some people may experience a shorter or longer duration.
Absorption
Nasowikoryl is rapidly absorbed through the mucous membranes of the nasal passages when administered topically. Its bioavailability is approximately 72%.
Route of Elimination
Nasowikoryl is primarily eliminated by hepatic metabolism.
Dosage
The recommended dosage for Nasowikoryl is typically 1-2 drops or sprays of 0.05% solution in the affected nostrils 2-3 times per day. Do not exceed more than 6 doses per day. For nasal polyps, the dosage is typically 2 sprays in the affected nostrils 3-4 times per day.
Administration
Nasowikoryl should be administered intranasally. Eliminate contact with eyes, and do not exceed dosage or duration of use as obstruction could occur.
Side Effects
While taking Nasowikoryl, common side effects may include irritation of the mucous membranes, sneezing, rhinorrhea, dryness, headache, and mild burning at the application site.
Toxicity
Nasowikoryl overdose can lead to serious effects such as hypertension, tachycardia, arrhythmias, circulatory collapse, and convulsions. Seek medical help if overdose is suspected.
Precaution
Nasowikoryl should not be used for more than 3 consecutive days or more than the recommended dose. Prolonged administration or excessive doses may cause a rebound effect in which the congestion returns with exaggerated intensity when Nasowikoryl is stopped. Discontinue use and contact a healthcare provider if any of these side effects occur.
Interaction
Nasowikoryl may interact with tricyclic antidepressants, phenothiazine derivatives, monoamine oxidase inhibitors, and other medications that have alpha-adrenergic blocking properties. If you are taking any of these medications, it is highly recommended to consult your physician before using Nasowikoryl.
Disease Interactions
Nasowikoryl may worsen certain medical conditions such as hypertension, stenocardia, arrhythmias, hyperthyroidism, and diabetes. If you have any of these conditions, it is advised to speak to your physician before using Nasowikoryl.
Drug Interactions
Since Nasowikoryl may interact with certain medications, it is important to tell your doctor if you are taking any medications, such as tricyclic antidepressants, phenothiazine derivatives, monoamine oxidase inhibitors, or medications that have alpha-adrenergic blocking properties. Do not start or stop any medication without consulting your doctor.
Food Interactions
No specific food interactions have been reported with Nasowikoryl. However, it is always advised to speak to your doctor before taking Nasowikoryl with any food or beverage, especially if you have an underlying medical condition.
Pregnancy Use
Nasowikoryl is not recommended for use in pregnant women due to lack of sufficient safety data. Women who are pregnant or planning to become pregnant should consult their doctor before using Nasowikoryl.
Lactation Use
Nasowikoryl is not recommended for use by breast-feeding women due to lack of sufficient safety data.
Acute Overdose
If Nasowikoryl overdose is suspected, seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Symptoms of overdose may include hypertension, tachycardia, arrhythmias, circulatory collapse, and convulsions.
Contraindication
Nasowikoryl should not be used by people who are allergic to it or any of its ingredients, people with glaucoma, people with narrow-angle glaucoma, people with severe heart disease, people with severe hypertension, people with an overactive thyroid, people with diabetes, and people who have taken a monoamine oxidase inhibitor (MAOI) within the past 14 days.
Use Direction
Nasowikoryl should be used as prescribed by your healthcare provider. For intranasal administration, the recommended dose is 1-2 drops or sprays of 0.05% solution in the affected nostrils 2-3 times per day. Do not exceed more than 6 doses per day or use for more than 3 consecutive days. Eliminate contact with eyes, and do not exceed dosage or duration of use as obstruction could occur.
Storage Conditions
Store Nasowikoryl at room temperature, away from light and moisture. Do not freeze. Keep it out of the reach of children and pets.
Volume of Distribution
The volume of distribution of Nasowikoryl is not known.
Half Life
The effective half-life of Nasowikoryl is about 4 hours.
Clearance
The clearance of Nasowikoryl is not known.
Here you find in details version of Nasowikoryl
Some Frequently Asked Questions About Nasowikoryl
What is Nasowikoryl?
Nasowikoryl is a decongestant medication used to treat symptoms of a common cold and allergic rhinitis, or hay fever.
How does Nasowikoryl work?
Nasowikoryl works by shrinking the blood vessels in the lining of the nose, which in turn reduces swelling and congestion.
What is Nasowikoryl used for?
Nasowikoryl is used to treat symptoms of colds and allergies, such as nasal congestion, sneezing, and itchy eyes.
Is Nasowikoryl safe to use?
Yes, Nasowikoryl is generally a safe medication to use as prescribed, however, it is important to use Nasowikoryl as directed.
When should I take Nasowikoryl?
Nasowikoryl should be taken as needed for symptoms of congestion, no more than three to four times per day. Do not take Nasowikoryl for longer than 3 days.
What are the side effects of Nasowikoryl?
Common side effects of Nasowikoryl include a dry or irritated nose or throat, nasal irritation or stinging, headaches, and nausea.
Is Nasowikoryl available over the counter?
Yes, Nasowikoryl is available over the counter at most pharmacies without a prescription.
Are there any interactions between Nasowikoryl and other medications?
Yes, some medications may interact with Nasowikoryl, so it is important to tell your healthcare provider about all medications and supplements that you are taking before using Nasowikoryl.
Can I use Nasowikoryl while pregnant?
Nasowikoryl is not recommended during pregnancy without your doctor's approval. If you are pregnant, make sure to tell your doctor before using Nasowikoryl.
Can Nasowikoryl help with ear congestion?
Nasowikoryl is generally not recommended for use in the ears; however, it may provide some relief to nasal congestion which can lead to ear congestion.
How long does it take for Nasowikoryl to work?
Nasowikoryl usually begins to work within a few minutes, however for some people it may take up to an hour to start to see relief.
Is Nasowikoryl habit forming?
Nasowikoryl is not habit forming when taken as directed. It is important to not take more than the recommended dose and to not take Nasowikoryl for longer than 3 days.
Can I use Nasowikoryl if I have high blood pressure?
If you have high blood pressure, talk to your doctor before taking Nasowikoryl as it may cause a slight raise in blood pressure.
What should I do if I have an allergic reaction to Nasowikoryl?
If you experience any signs of an allergic reaction, such as swelling of the face, lips, or tongue, difficulty breathing, or hives, contact your healthcare provider immediately.
Should I use Nasowikoryl with a neti pot?
Nasowikoryl should not be used in the neti pot as it can cause irritation to the nose and throat. If using a neti pot, only use a saline solution.
What other medications can be used to treat congestion?
Other medications, such as antihistamines, nasal steroid sprays, and expectorants, can also be used to treat congestion. Speak to your healthcare provider to determine which medication is best for you.
Can I use Nasowikoryl and an antihistamine together?
Yes, Nasowikoryl and antihistamines can be used together, however, it is important to speak to your healthcare provider before using both medications together.
What is the difference between Nasowikoryl and pseudoephedrine?
Nasowikoryl and pseudoephedrine are both decongestants, however, pseudoephedrine is a stronger medication and is only available by prescription.
Can Nasowikoryl be used for a cold?
Yes, Nasowikoryl can be used to treat symptoms of colds, such as congestion, sneezing, and itchy eyes.
Is Nasowikoryl safe for children?
Nasowikoryl is generally safe for children, however it is important to consult your healthcare provider before giving Nasowikoryl to a child.
Can Nasowikoryl cause drowsiness?
Nasowikoryl generally does not cause drowsiness, however it is important to speak with your healthcare provider if you experience any unusual side effects while taking Nasowikoryl.
Can Nasowikoryl be used for sinus congestion?
Yes, Nasowikoryl can be used to treat sinus congestion.
Is Nasowikoryl addictive?
Nasowikoryl is not considered addictive as long as it is used as directed and not taken for longer than 3 days.
What is the dosage for Nasowikoryl?
The recommended dosage of Nasowikoryl is two sprays in each nostril every 8 to 12 hours, as needed for up to 3 days.
How do I use Nasowikoryl?
Nasowikoryl should be used as directed on the package instructions or as prescribed by your healthcare provider. Shake the bottle well before using, and insert two sprays in each nostril every 8 to 12 hours, as needed, for up to 3 days.
Can I use Nasowikoryl if I have glaucoma?
Nasowikoryl can increase the pressure in the eyes and should not be used in people with glaucoma.
Can I use Nasowikoryl if I have asthma?
Nasowikoryl can cause bronchospasms in some people with asthma, so it is important to speak to your healthcare provider before using Nasowikoryl.
Is Nasowikoryl a steroid?
No, Nasowikoryl is not a steroid; it is a decongestant medication.
Can I use Nasowikoryl if I have diabetes?
Nasowikoryl is generally safe for people with diabetes. However, if your blood sugar is frequently low, it is important to talk to your healthcare provider before taking Nasowikoryl.
Can Nasowikoryl be used long-term?
No, Nasowikoryl should not be used for more than 3 days as it can cause damage to the nasal tissues and lead to rebound congestion.
Can Nasowikoryl help to reduce a fever?
No, Nasowikoryl is not effective in reducing fevers, so it should not be used to treat fevers.
Does Nasowikoryl have any anti-inflammatory properties?
No, Nasowikoryl does not have any anti-inflammatory properties; it works by constricting the blood vessels in the lining of the nose, which reduces congestion.
Is Nasowikoryl safe to use while breastfeeding?
Nasowikoryl is not known to be harmful when taken while breastfeeding, however it is important to consult with your healthcare provider before taking Nasowikoryl if you are breastfeeding.
Can I use Nasowikoryl if I have high cholesterol?
Nasowikoryl can be used if you have high cholesterol, however, it is important to speak to your healthcare provider before taking it.
Can Nasowikoryl cause headaches?
Yes, Nasowikoryl can cause headaches in some people; if you experience headaches while taking Nasowikoryl, consult your doctor.
Can Nasowikoryl make congestion worse?
Yes, if Nasowikoryl is used for longer than 3 days, it can cause rebound congestion due to the nasal tissue becoming used to the medication.
Can Nasowikoryl be used with other cold or allergy medications?
Yes, Nasowikoryl can be used in combination with other cold and allergy medications, however it is important to speak to your healthcare provider before using multiple medications at the same time.
Can Nasowikoryl cause stomach upset?
Yes, Nasowikoryl can cause stomach upset in some people; if you experience stomach upset while taking Nasowikoryl, contact your healthcare provider.
Does Nasowikoryl have any antiseptic properties?
No, Nasowikoryl does not have any antiseptic properties, it is a decongestant medication.
Can Nasowikoryl be used with other medications?
Nasowikoryl can be used with other medications, however certain medications may interact with Nasowikoryl, so it is important to tell your healthcare provider about all medications and supplements that you are taking before using Nasowikoryl.