Nasathera P
Nasathera P Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Nasathera P is a brand name. Its generic name is Phenylpropanolamine.
Nasathera P Introduction
Nasathera P (PPA) is an artificially synthesized chemical compound. It is used in the treatment of cold symptoms, allergies, ADHD, and behavioral disorders and is also an active ingredient in appetite suppressants. It is classed as an indirect sympathomimetic drug due to its main use as a decongestant and its ability to increase the blood pressure.
Uses for Nasathera P
Nasathera P is used to treat and relieve cold symptoms and may be used to treat allergies, asthma, and other breathing disorders. It may also be used to treat Attention Deficit Hyperactivity Disorder (ADHD), behavioral disorders, and as an appetite suppressant.
Mechanism of Action
Nasathera P works as an indirect sympathomimetic drug. It stimulates the sympathetic nervous system (SNS), which has a major role in physiological activities like digestion, breathing rhythm, and pupil size. It also increases the Noradrenaline which helps in reducing inflammation, bronchoconstriction, and release of mucus.
How Long Does it Take to Work?
Nasathera P usually starts to work in a matter of minutes. However, the effects vary depending on the condition being treated and might take anywhere from 30-60 minutes to become fully effective.
Absorption
Nasathera P is rapidly absorbed from the gastrointestinal tract but is subject to first-pass metabolism in the liver. Its peak effect is observed within 2-3 hours after administration. Its elimination half-life is 6-17 hours.
Route of Elimination
Nasathera P is rapidly eliminated primarily via the kidneys. Its metabolites are also eliminated via the feces.
Dosage
The dosage of Nasathera P depends on the age, weight and medical condition of the patient. The usual dosage range for adults is 75 mg to 150 mg. For children, the recommended dosage range is 25 mg to 50 mg. It is important to strictly follow the dosage prescribed by the physician. Overdose can lead to serious side effects.
Administration
Nasathera P can be taken orally with or without food. It is available in the form of tablets, capsules, or syrup. Before taking it, make sure to talk to your doctor. Ask your doctor or pharmacist any questions you may have about how to take the medicine.
Side Effects
Nasathera P may cause side effects such as nausea, vomiting, dry mouth, blurred vision, headache, dizziness, insomnia, restlessness, irritability, confusion, heart palpitations, and other cardiovascular side effects. It may also cause anxiety and disorientation.
Toxicity
High doses of Nasathera P can cause toxicity, including seizures, stroke, coma, and even death. Therefore, it is important to never take more than the recommended dose or more than the prescription provided by your doctor.
Precautions
It is important to speak to your doctor or healthcare provider before taking Nasathera P in order to reduce the risk of any potential side effects as well as drug interactions. It is also important to tell your doctor if you have any pre-existing medical conditions, especially cardiovascular or psychiatric issues, before taking this medication.
Interaction
Nasathera P can interact with certain drugs such as Monoamine Oxidase Inhibitors (MAOIs), tricyclic antidepressants, and other sympathomimetic agents. This can cause an increase in the side effects of the drug. It is important to tell your doctor about all medications and supplements that you are taking before starting Nasathera P.
Disease Interaction
Patients with certain medical conditions can interact with Nasathera P. These include high blood pressure, heart disease, and psychiatric conditions such as mania, depression, and panic disorder. It is important to tell your doctor about any pre-existing medical conditions prior to taking this medication.
Drug Interaction
Nasathera P can interact with other medications, especially MAOIs and tricyclic antidepressants. This can lead to increased side effects such as confusion, restlessness, irritability, and elevated blood pressure. It is important to speak to your doctor before taking any other medications, including over the counter medication and herbal remedies, while taking Nasathera P.
Food Interactions
Nasathera P may interact with certain foods and beverages, such as alcohol and caffeine. It is important to pay attention to how food and drinks seem to interact with the medication. Tell your doctor if you have any allergies to food and drinks before taking Nasathera P.
Pregnancy Use
It is not recommended to take Nasathera P while pregnant, as there is not enough information available to assess its safety during pregnancy. It is important to talk to your doctor before taking this medication if you are pregnant or potentially pregnant.
Lactation Use
It is not recommended to take Nasathera P while breastfeeding, as there is not enough information available to assess its safety in breastmilk. It is important to talk to your doctor before taking this medication if you are breastfeeding or plan to breastfeed.
Acute Overdose
Acute overdose of Nasathera P can cause hypertension, tachycardia, restlessness, disorientation, confusion, coma, and cardiovascular collapse. In cases of overdose, seek medical attention right away.
Contraindications
Nasathera P is contraindicated in patients with pre-existing cardiovascular ailments, pregnant and nursing mothers, children below the age of 12, and those who are hypersensitive to the drug.
Use Direction
Read all medication guides and instructions carefully before starting to use Nasathera P. Do not exceed the recommended dose and always take it exactly as prescribed by your doctor. Talk to your doctor if you are unsure about anything related to this medication.
Storage Conditions
Store Nasathera P at room temperature away from light and moisture. Keep this medication out of reach of children and pets.
Volume of Distribution
Nasathera P has a volume of distribution of 130 liters. This indicates its wide tissue distribution.
Half-Life
The elimination half-time for Nasathera P is 6-17 hours.
Clearance
Nasathera P has a clearance rate of 122-178 mL/min.
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