Myladerm

Myladerm Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Myladerm is a brand name. Its generic name is Clobetasol Propionate + Ofloxacin + Ornidazole + Terbinafine.

Introduction

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine are a combination drug used to treat superficial fungal and bacterial infections of the skin, including ringworm and athlete’s foot. It is available as a cream, gel, and lotion.

Uses For

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is mainly used to treat infections of the feet caused by fungi or bacteria. It is also used to treat other types of fungal skin infections, including ringworm and other conditions such as contact dermatitis.

Mechanism of Action

Clobetasol Propionate is a synthetic corticosteroid with immunosuppressant and anti-inflammatory effects. It works by blocking the release of certain natural substances that cause inflammation in the body. Ofloxacin is an antibiotic that works by stopping the growth of bacteria. Ornidazole is a synthetic antiprotozoal used to treat infections caused by protozoa such as trichomoniasis, giardiasis, and amebiasis. Terbinafine, an antifungal, works by killing or stopping the growth of fungi that cause infections.

How Long Does It Take to Work?

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination typically takes two to four weeks before the infection is fully cleared up. The duration of treatment depends on the severity of the infection.

Absorption

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is rapidly absorbed through the skin. Peak levels of the drug are reached within 2-4 hours of administration, and the drug is rapidly metabolized and excreted by the body.

Route of Elimination

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is eliminated from the body mainly through the kidneys and feces.

Dosage

The dosage of Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination depends on the severity of the infection and the patient’s age and weight. The dosage for treating fungal skin infections in adults is 0.05% clobetasol propionate, 0.25% ofloxacin, 0.02% ornidazole, and 0.01% terbinafine applied topically twice daily, for up to 4 weeks. For bacterial skin infections, the dosage is 0.05% clobetasol propionate, 0.25% ofloxacin, 0.02% ornidazole applied topically three times daily, for up to 4 weeks.

Administration

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is applied directly to the affected area of the skin, two to three times daily. It should not be applied to the face, underarms, or genitals. The cream should be rubbed in lightly, until it disappears.

Side Effect

The most common side effects of Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination include irritation and burning at the site of application, itching, redness, dryness, and rash.

Toxicity

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is generally considered to be safe. Overdose of the drug may cause benign adverse reactions, however serious or life-threatening toxicities have not been reported.

Precaution

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination should not be used on open wounds, broken skin, or mucous membranes. The drug should also be used with caution in patients with kidney or liver disease, as the drug may be metabolized more slowly in these individuals and lead to higher levels of drug in the body.

Interaction

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination may interact with other drugs such as antacids, NSAIDs, steroids, or other topical medications. It is important to tell the health care provider about all other drugs being taken to avoid drug interactions.

Disease Interaction

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination may be unsafe for patients with certain medical conditions such as diabetes, kidney disease, liver disease, or an immunosuppressed state. It is important to tell the health care provider about any relevant medical conditions before starting treatment.

Drug Interaction

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination may interact with other drugs such as antacids, NSAIDs, steroids, or other topical medications. It is important to tell the health care provider about all other drugs being taken to avoid drug interactions.

Food Interactions

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination may interact with certain foods such as dairy products, which could reduce the absorption of the medication. It is important to tell the health care provider about any relevant dietary restrictions before starting treatment.

Pregnancy Use

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is not recommended for use during pregnancy. The safety of this drug during pregnancy has not been established, therefore it should be used with caution.

Lactation Use

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is not recommended for use during breastfeeding. The safety of this drug during lactation has not been established, therefore it should be used with caution.

Acute Overdose

An acute overdose of Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is unlikely to produce serious symptoms, however symptoms such as increased thirst, headache, nausea, vomiting, dizziness, drowsiness, and/or confusion may occur.

Contraindication

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is contraindicated in patients with a history of hypersensitivity to any of the components of the drug.

Use Direction

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination should be used as directed by a healthcare provider. It should be applied directly to the affected area of the skin twice to three times daily, for up to 4 weeks. It should not be applied to the face, underarms, or genitals.

Storage Condition

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination should be stored at room temperature and away from excessive heat, moisture, and light.

Volume of Distribution

The volume of distribution of Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is not determined.

Half Life

Clobetasol Propionate has an elimination half-life of about 5 hours, while Ofloxacin and Ornidazole have an elimination half-life of about 12 hours. The elimination half-life of Terbinafine is not known.

Clearance

Clobetasol Propionate, Ofloxacin, Ornidazole and Terbinafine combination is cleared from the body mainly through the kidneys and feces.

Here you find in details version of Myladerm

Some Frequently Asked Questions About Myladerm

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Q1. What is Myladerm?

Myladerm is a combination medication used to treat fungal skin infections caused by a particular fungus (dermatophytes).

Q2. How to use Myladerm?

Myladerm should be applied to the affected area of the skin two to three times a day according to instructions given by your doctor.

Q3. What should I avoid while using Myladerm?

It is important to avoid accidental contact with the eyes or nose when using Myladerm. Also, avoid contact with open wounds or skin lesions when using the medication.

Q4. What are the possible side effects of Myladerm?

The possible side effects of Myladerm include itching, burning, irritation and redness. Rarely, more serious reactions such as anaphylaxis and Stevens-Johnson Syndrome may occur.

Q5. How long should I use Myladerm?

You should use Myladerm for as long as directed by your doctor. Usually, the treatment period ranges between two weeks and a month.

Q6. Is Myladerm safe for children?

Myladerm is not recommended for use in children below the age of 12. Talk to a doctor if you are unsure about the suitability of this medication for your child.

Q7. Does Myladerm contain steroids?

Myladerm contains the active ingredient clobetasol propionate, which is a corticosteroid.

Q8. Can Myladerm be used on the face?

Myladerm is generally not recommended for use on the face. Consult a doctor for advice if you need to use the medication on the face.

Q9. Is Myladerm habit-forming?

No, Myladerm is not habit-forming.

Q10. Is Myladerm safe to use during pregnancy?

Myladerm is not recommended for use during pregnancy, as its safety during pregnancy has not been established. If necessary, consult a doctor to decide on the safest alternative.

Q11. How long do I need to wait before I can expect the effects of Myladerm to take effect?

The effects of Myladerm usually take a few days to take effect, depending on the severity of the infection. However, it is important to take the medication for as long as directed by the doctor.

Q12. Is Myladerm safe to use for a long period of time?

Yes, Myladerm can be safely used for a long period of time, as advised by your doctor.

Q13. Can Myladerm cause skin discoloration?

Yes, prolonged use of Myladerm can cause skin discoloration, especially in dark-skinned individuals.

Q14. Is Myladerm a steroid cream?

Yes, Myladerm is a steroid cream.

Q15. How long after applying Myladerm can I wash the affected area?

It is recommended to wait at least 20 minutes after applying Myladerm beforewashing the affected area.

Q16. Is Myladerm suitable for sensitive skin?

Myladerm may cause irritation in people with sensitive skin. It is recommended to use a milder form of this medication if you have sensitive skin.

Q17. What should I do if I experience any side effects while using Myladerm? 

If you experience any side effects while using Myladerm, stop using it and contact your doctor immediately.

Q18. Is Myladerm safe to use during lactation? 

Myladerm is not recommended for use during lactation, as its safety has not been established.

Q19. Can I apply Myladerm before bedtime?

Yes, Myladerm can be applied before bedtime.

Q20. Should I use Myladerm on broken skin?

No, Myladerm should not be used on broken skin.

Q21. Will Myladerm cure my skin infection in one use?

No, Myladerm is not meant to cure your skin infection in one application. You need to use it for the full course as prescribed by your doctor.

Q22. When should I discontinue using Myladerm?

You should discontinue using Myladerm when you no longer have the symptoms of the infection. Continue using it for as long as the doctor has advised.

Q23. Does Myladerm cause skin thinning?

Yes, long-term or overuse of Myladerm can cause skin thinning. If this happens, notify your doctor immediately.

Q24. Is Myladerm available over the counter?

No, Myladerm is not available over the counter. It can only be obtained with a valid prescription from a doctor.

Q25. Does Myladerm cause drowsiness?

No, Myladerm does not cause drowsiness.

Q26. Is it safe to drive after taking Myladerm?

Yes, it is safe to drive after taking Myladerm.

Q27. Should I use Myladerm for treating a fungal nail infection?

No, Myladerm is not suitable for treating a fungal nail infection. Talk to your doctor for the best course of treatment for a fungal nail infection.

Q28. Is Myladerm approved by the FDA?

Yes, Myladerm is approved by the US Food and Drug Administration (FDA).

Q29. Can I use Myladerm for treating a jock itch?

Yes, Myladerm can be used for treating jock itch.

Q30. Does Myladerm have any drug interactions?

Myladerm may interact with some medications such as systemic corticosteroids, cholesterol-lowering drugs, some antiseizure medications, and some HIV medications. Therefore, it is important to inform your doctor about all the medications you are using before taking Myladerm.