Metoprolol and hydrochlorothiazide
Metoprolol and hydrochlorothiazide Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Metoprolol and hydrochlorothiazide is a brand name. Its generic name is Metoprolol + Hydrochlorothiazide.
Introduction
Metoprolol and hydrochlorothiazide is a combination medication used for treating high blood pressure and angina (chest pain). It is a prescription drug that contains two drugs, metoprolol tartrate and hydrochlorothiazide. Metoprolol is a beta blocker that works by decreasing the amount of cholesterol in the blood, while hydrochlorothiazide is a diuretic drug that works by removing salt from the body, helping to control high blood pressure. This combination medication is effective in treating both conditions at once.Uses For
Metoprolol and hydrochlorothiazide is a combination medication used for the treatment of hypertension (high blood pressure) and angina (chest pain). It is also used to reduce the risk of death and hospitalization in people with heart failure.Mechanism of Action
Metoprolol and hydrochlorothiazide works by two different mechanisms. Metoprolol is a beta blocker, which works by blocking the action of certain hormones that raise the blood pressure. Hydrochlorothiazide is a diuretic, which works by increasing the amount of salt and water removed from the body, helping to control blood pressure.How Long Does It Take To Work?
The effects of Metoprolol and hydrochlorothiazide may be seen within a few hours of taking the medication. It can take up to two weeks for optimal results.Absorption
The absorption of Metoprolol and hydrochlorothiazide is rapid and complete. The drug is absorbed quickly from the gastrointestinal tract and is rapidly distributed throughout the body.Route of Elimination
Metoprolol and hydrochlorothiazide is primarily metabolized in the liver, with small amounts excreted in the urine and feces. Most of the drug is eliminated in the urine.Dosage and Administration
Metoprolol and hydrochlorothiazide is available in tablet form in strengths of 25 mg/12.5 mg, 50 mg/12.5 mg, 100 mg/12.5 mg, and 200 mg/25 mg. The recommended starting dose is 25 mg/12.5 mg once daily. Your healthcare provider may increase your dose up to 200 mg/25 mg if necessary, but should not exceed this dose.Side Effects
Common side effects of Metoprolol and hydrochlorothiazide include dizziness, headache, fatigue, nausea, vomiting, and diarrhea. Other side effects may include abdominal pain, heartburn, joint pain, and rash.Toxicity
Metoprolol and hydrochlorothiazide is generally well tolerated in most people. It is not likely to cause serious toxicity with normal use.Precautions
People with certain medical conditions or taking certain medications may have increased risk of side effects from Metoprolol and hydrochlorothiazide. It is important to tell your healthcare provider about all medications you are taking, especially if you have asthma, diabetes, or kidney disease.Interaction
Metoprolol and hydrochlorothiazide may interact with other medications. Talk to your healthcare provider about all medications you are taking, including over-the-counter medications, vitamins, and herbal supplements.Disease Interaction
Metoprolol and hydrochlorothiazide may not be safe for people with certain medical conditions. Talk to your healthcare provider about any conditions you have before taking this medication.Drug Interaction
Metoprolol and hydrochlorothiazide may interact with certain drugs. Talk to your healthcare provider about any medications you are taking, including over-the-counter medications, vitamins, and herbal supplements.Food Interactions
Metoprolol and hydrochlorothiazide may interact with certain foods. Talk to your healthcare provider about any foods that may interact with this medication.Pregnancy Use
Metoprolol and hydrochlorothiazide is not recommended for use during pregnancy, as it may cause harm to an unborn baby. Talk to your healthcare provider about other medications that may be more appropriate for you.Lactation Use
Metoprolol and hydrochlorothiazide is also not recommended for use while breastfeeding, as it may be passed to a nursing infant through breast milk. Talk to your healthcare provider about other medications that may be more appropriate for you.Acute Overdose
If an overdose of Metoprolol and hydrochlorothiazide is suspected, seek medical attention immediately. Symptoms of overdose may include dizziness, confusion, nausea, vomiting, and fast or irregular heartbeat.Contraindication
Metoprolol and hydrochlorothiazide is contraindicated in people with a known allergy or hypersensitivity to metoprolol, hydrochlorothiazide, or any other ingredient in the medication. It should also be used with caution in people with diabetes, thyroid disease, or kidney or liver damage.Use Direction
Metoprolol and hydrochlorothiazide should be taken as prescribed by your healthcare provider. Talk to your healthcare provider about how often and when to take the medication. Typically, metoprolol + hydrochlorothiazide is taken once daily, with or without food. It is important to take your medication at the same time each day.Storage Conditions
Metoprolol and hydrochlorothiazide should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children.Volume of Distribution
The volume of distribution of Metoprolol and hydrochlorothiazide is 40 to 80 liters.Half Life
The half life of Metoprolol and hydrochlorothiazide is 6 to 8 hours.Clearance
The clearance of Metoprolol and hydrochlorothiazide is 10 to 30 ml per minute.Here you find in details version of Metoprolol and hydrochlorothiazide