Mediclovir

Mediclovir Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Mediclovir is a brand name. Its generic name is Aciclovir.

Mediclovir Introduction

Mediclovir, also known as Acyclovir, is an antiviral medication used to treat a variety of herpes-related infections, such as shingles, genital herpes, and chickenpox. It is an oral medication available in both tablet and oral suspension form. It is also available in topical cream form.

Uses for Mediclovir

Mediclovir is used to treat and prevent infections such as herpes simplex virus (HSV)1 and 2, chickenpox, and shingles. It is used to reduce pain and heal sores caused by these infections. It can also help to prevent the spread of the infections.

Mechanism of Action

Mediclovir works by stopping the virus from making more copies of itself. It does this by stopping the activity of an enzyme the virus needs to replicate. This stops the virus from spreading, and ultimately helps it to clear up.

How Long Does It Take to Work?

Mediclovir may take up to 2 days for the viral shedding to reduce. It is important to note that the virus can still be passed on during this time. For the best results, Mediclovir should be taken for the full course of treatment, which can be up to 5 days.

Absorption

Mediclovir is rapidly and almost completely absorbed from the gastrointestinal tract. It is approximately 20% bio available, which means it should be taken with food or milk to enhance its absorption.

Route of Elimination

Mediclovir is eliminated via the kidneys, primarily as unchanged (or active) drug. Approximately 20–30% will be eliminated in the urine as inactive metabolites.

Dosage

Dosage of Mediclovir will depend on the type of infection being treated. The usual adult dosage for herpes simplex virus infections is 200-400 mg by mouth 5 times daily, up to five days. For genital herpes, the dosage is 200mg every 4 hours (6 doses per day), up to five days. For shingles, the dosage is 800mg five times per day for 7-10 days.

Administration

Mediclovir can be taken with or without food. It is important to take it regularly and exactly as your doctor prescribes. Do not stop taking it, even if you feel better, unless your doctor tells you to.

Side Effect

Common side effects of Mediclovir include nausea, stomach pain, headache, dizziness, and feeling tired. Some patients may experience an allergic reaction such as hives or difficulty breathing, which should be reported to their healthcare provider immediately.

Toxicity

Mediclovir has a low risk of toxicity when taken as directed and following your healthcare provider's instructions. The most common adverse reactions are gastrointestinal disturbances such nausea, vomiting, and diarrhea.

Precautions

Patients with kidney or liver disease should use Mediclovir with caution. Mediclovir should not be taken during pregnancy, unless prescribed by a healthcare provider. Before taking Mediclovir, it's important to let your healthcare provider know if you have any allergies, sensitivities, or other health conditions.

Interactions

Mediclovir may interact with other medications such as probenecid, tubocurarine, certain antibiotics, and some antacids. It's important to tell your healthcare provider if you are taking other medications or supplements.

Disease Interaction

Patients with a compromised immune system, such as those with HIV, and those with kidney or liver disease, should use Mediclovir with caution as it can cause more serious side effects. It is also important for these patients to follow their healthcare provider’s instructions.

Drug Interactions

Mediclovir may interact with medications such as probenecid, tubocurarine, certain antibiotics, and some antacids. Tell your doctor if you are taking any other medications or supplements.

Food Interactions

Mediclovir should be taken with food or milk to enhance its absorption. Its effectiveness can also be decreased if taken with certain foods.

Pregnancy Use

Mediclovir should not be taken during pregnancy, unless prescribed by a healthcare provider. It can pass into breast milk, so it should not be taken by breastfeeding mothers.

Lactation Use

Mediclovir should not be used by breastfeeding mothers. It can pass into breast milk and can harm a nursing baby.

Acute Overdose

An overdose of Mediclovir may lead to severe and even life-threatening side effects. It is important to contact your healthcare provider or local poison control center as soon as possible if you think you may have taken too much Mediclovir.

Contraindication

Mediclovir is contraindicated in patients who are allergic or hypersensitive to it. It is also contraindicated in patients with renal impairment or severe hepatic impairment.

Use Direction

It is important to follow the instructions of your healthcare provider when taking Mediclovir. Do not take more or less medication than prescribed or discontinue taking the medication abruptly without consulting your healthcare provider.

Storage Condition

Store Mediclovir tablets at room temperature away from moisture and heat. Keep the suspension form in the fridge (but not in the freezer).

Volume of Distribution

The volume of distribution is 0.2-1L/kg for Mediclovir.

Half Life

The average half life is 2.0 to 4.7 hours for Mediclovir.

Clearance

The average clearance of Mediclovir is 0.1 L/hr/kg.

Here you find in details version of Mediclovir

Some Frequently Asked Questions About Mediclovir

What is Mediclovir?

Mediclovir is an antiviral drug used to treat infections caused by certain types of viruses. It is most commonly used to treat ‘cold sores’ (herpes simplex) and ‘genital herpes’ (genital herpes infections).

What are the uses of Mediclovir?

Mediclovir is used to treat infections caused by herpes viruses, such as genital herpes, cold sores, shingles, and chicken pox.

What form does Mediclovir come in?

Mediclovir is available as a tablet, an oral suspension, and a topical cream.

How does Mediclovir work?

Mediclovir works by stopping the virus from multiplying and spreading, and so helps to reduce the severity and duration of the infection. However, it does not cure the infection.

How should Mediclovir be taken?

Mediclovir should be taken as directed on the label, or as prescribed by your doctor. It is usually taken with food. The dosage and length of treatment will depend on the type and severity of infection.

Who should not take Mediclovir?

Mediclovir should not be taken by people who are allergic to it or any of its ingredients, and by pregnant or breastfeeding women.

What are the side effects of Mediclovir?

Side effects of Mediclovir include nausea, vomiting, diarrhea, headache, rash, and dizziness.

Can Mediclovir be taken with other medications?

Mediclovir may interact with other medications, such as warfarin and probenecid, so it is important to tell your doctor about all medications you are taking.

What should be done in case of an overdose?

If an overdose of Mediclovir is suspected, contact a poison control center or emergency room immediately.

What should I do if I miss a dose?

If you miss a dose of Mediclovir, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

How long should I take Mediclovir?

The length of treatment with Mediclovir will depend on the type and severity of the infection. Follow all instructions given to you by your doctor.

Can I buy Mediclovir over-the-counter?

No, Mediclovir is available only with a doctor’s prescription.

What is the most common brand name for Mediclovir?

The most common brand name for Mediclovir is Zovirax.

Does Mediclovir cause drowsiness?

Yes, Mediclovir may cause drowsiness. It is important to use caution when operating heavy machinery or driving while taking Mediclovir.

How long does it take for Mediclovir to start working?

Mediclovir usually starts to work within a few days, but it can take up to a week or more for symptoms to resolve.

Can Mediclovir be used to treat infections other than those caused by herpes viruses?

No, Mediclovir is not effective against infections caused by other types of viruses.

What is the recommended dosage of Mediclovir?

The recommended dosage of Mediclovir will vary depending on the type and severity of the infection. Follow all instructions on the label or as prescribed by your doctor.

Can Mediclovir be used in children?

Yes, Mediclovir can be used in children over the age of two. Children younger than two years should not take Mediclovir.

Is Mediclovir safe for pregnant or breastfeeding women?

No, Mediclovir should not be taken by pregnant or breastfeeding women, as it can harm the baby.

How long does Mediclovir stay in the body?

The half-life of Mediclovir is around 2-4 hours, meaning it is generally out of the body within a day or two.

What are the storage instructions for Mediclovir?

Mediclovir should be stored at room temperature, away from heat and moisture. Keep out of reach of children.

Should Mediclovir be taken with food?

It is recommended to take Mediclovir with food.

Can Mediclovir be used to prevent infections?

In some cases, Mediclovir can be used to prevent infections. Consult your doctor for more information.

Can Mediclovir be used to treat shingles?

Yes, Mediclovir is an effective treatment for shingles. It is important to start treatment as soon as possible.

What should I do if I experience any allergic reactions while taking Mediclovir?

If you experience any allergic reactions while taking Mediclovir, discontinue use and contact your doctor immediately.

Can Mediclovir cause weight gain?

No, Mediclovir does not cause weight gain.

Is Mediclovir an antibiotic?

No, Mediclovir is an antiviral drug, not an antibiotic.

Can Mediclovir be used during an outbreak?

Yes, Mediclovir can be used to treat a herpes outbreak.

Can Mediclovir be used to treat cold sores?

Yes, Mediclovir is an effective treatment for cold sores.

What are the side effects of Mediclovir in children?

The most common side effects of Mediclovir in children are nausea, vomiting, diarrhea, headache, rash, and dizziness.

How soon after taking Mediclovir should I expect to see improvement?

You may see some improvement in symptoms within a few days of starting Mediclovir, but it can take up to a week or more for full symptom relief.

What should I do if I experience any other side effects while taking Mediclovir?

If you experience any other side effects while taking Mediclovir, contact your doctor immediately.

Are there any interactions between Mediclovir and alcohol?

Yes, alcohol can interact with Mediclovir and should be avoided while taking the medication.

Can I take Mediclovir with other medicines?

It is important to tell your doctor about all medications you are taking, including over-the-counter medications and dietary supplements, as Mediclovir can interact with some medications. Your doctor will advise you on any potential interactions.

Are there any long-term side effects associated with using Mediclovir?

No, there are no known long-term side effects associated with Mediclovir.

Does Mediclovir have any effect on the effectiveness of birth control?

No, Mediclovir does not have any effect on the effectiveness of birth control.

What is the recommended dose of Mediclovir in children?

The recommended dose of Mediclovir in children will depend on the child's body weight and the type and severity of the infection. Consult your doctor for specific dosage and dosing interval recommendations.

What are the possible side effects of Mediclovir in infants?

The most common side effects of Mediclovir in infants are nausea, vomiting, diarrhea, headache, rash, and dizziness.

Can Mediclovir be used for long-term treatment?

In some cases, Mediclovir may be used for long-term treatment. Consult your doctor for specific recommendations.

Can Mediclovir be used to treat chickenpox?

Yes, Mediclovir can be used to treat chickenpox in children over the age of two.

Is Mediclovir safe to take with other medicines?

Yes, Mediclovir is generally safe to take with other medications, but you should always tell your doctor about all medications you are taking as some interactions may occur.

Does Mediclovir cause any upset stomach?

Yes, Mediclovir may cause mild stomach upset, such as nausea, vomiting, and diarrhea.

Can Mediclovir be used to treat genital herpes?

Yes, Mediclovir is an effective treatment for genital herpes.

Does Mediclovir interact with any other drugs?

Yes, Mediclovir can interact with other medications. It is important to tell your doctor about all medications you are taking as some interactions may occur.

Can Mediclovir be taken with other vitamins or supplements?

It is important to tell your doctor about all vitamins, herbal supplements, and medications you are taking, as some may interact with Mediclovir.