Malirid Ds

Malirid Ds Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Malirid Ds is a brand name. Its generic name is Primaquine.

Introduction

Malirid Ds is an antimalarial medication used to treat and prevent certain types of malaria. It is also used as a prophylaxis, which is used to prevent the further spread of malaria after initial treatment. Malirid Ds belongs to a group of antimalarials called 8-amino-quinolines.

Uses For

Malirid Ds is used to treat and prevent certain types of malaria caused by Plasmodium falciparum and Plasmodium vivax. It is also used as a prophylaxis (preventive medication) against further accusations of malaria in travelers in areas that are infected with Plasmodium vivax and Plasmodium falciparum. Malirid Ds should not be used in children under 8 years old.

Mechanism Of Action

Malirid Ds works by interfering with two essential proteins involved in the synthesis of DNA in the malaria parasite. It inhibits the enzyme dihydrofolate reductase and interferes with the electron transport system, both of which are essential for the parasite to survive. Malirid Ds also has a role in preventing the transmission of the malaria parasite to uninfected mosquito vectors.

How Long Does It Take To Work?

Malirid Ds usually takes effect within 1-2 hours of ingestion. The effects of Malirid Ds can last up to 48 hours, so it is important to take the medication as prescribed by a physician.

Absorption

Malirid Ds is absorbed quickly and completely from the gastrointestinal tract. It has an apparent volume of distribution of 1.31 L/kg and an apparent bioavailability of 42%.

Route Of Elimination

Malirid Ds is eliminated primarily by the kidneys. It has an elimination half-life of 23 hours.

Dosage

The recommended dosage for Malirid Ds depends on the condition being treated. For prophylaxis, the usual dosage is 15mg orally once daily for 7 days. For treatment of acute malaria, the usual dosage is 15mg orally once daily for 14 days. It is important to take Malirid Ds exactly as prescribed by a physician.

Administration

Malirid Ds should be taken with food or a full glass of water. It should be taken at the same time each day to maintain an even level of medication in the bloodstream.

Side Effects

The most common side effects of Malirid Ds include nausea, vomiting, headache, dizziness, loss of appetite, hair loss, hepatitis, rash, and anemia.

Toxicity

The toxic effects of Malirid Ds include changes in behavior, disorientation, difficulty breathing, and seizures.

Precautions

Before taking Malirid Ds, it is important to inform your physician if you have liver or kidney disease, blood disorders, glucose-6-phosphate dehydrogenase (G6PD) deficiency, or any allergies.

Interactions

Malirid Ds can interact with other drugs, including antacids, certain antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs).

Disease Interactions

Malirid Ds can worsen certain diseases, including cancer, diabetes, anemia, and liver or kidney disease.

Drug Interactions

Malirid Ds can interact with certain drugs, including antacids, certain antibiotics, and nonsteroidal anti-inflammatory drugs (NSAIDs).

Food Interactions

It is important to take Malirid Ds with food to reduce the risk of interactions.

Pregnancy use

Malirid Ds should not be used in pregnant women, as it may cause serious birth defects.

Lactationuse

Malirid Ds should not be used while breastfeeding as it may be passed to the infant through breast milk.

Acute Overdose

The symptoms of an acute overdose may include severe abdominal pain, nausea, vomiting, seizures, and difficulty breathing. If you suspect an overdose, contact your local poison control center or emergency room immediately.

Contraindication

Malirid Ds should not be used in people with certain conditions, including porphyria, G6PD deficiency, severe anemia, and hemolytic anemia.

Use Direction

Malirid Ds should be taken as prescribed by a physician. Do not take more or less than the recommended amount.

Storage Condition

Malirid Ds should be stored in a cool, dry place, at room temperature. Keep out of reach of children and pets.

Volume Of Distribution

Malirid Ds has an apparent volume of distribution of 1.31 L/kg.

Half Life

Malirid Ds has an elimination half-life of 23 hours.

Clearance

Malirid Ds is eliminated primarily by the kidneys.

Here you find in details version of Malirid Ds

Some Frequently Asked Questions About Malirid Ds

What is Malirid Ds?

Malirid Ds is an antimalarial medication used to treat and prevent malaria infection.

How does Malirid Ds work?

Malirid Ds works by killing the malaria parasites in the liver. It also prevents the parasites from multiplying and spreading.

What is the active ingredient in Malirid Ds?

The active ingredient in Malirid Ds is primaquine phosphate.

How long does it take for Malirid Ds to work?

Malirid Ds typically begins to work within 24 hours of taking the medication.

What are the side effects of Malirid Ds?

Typical side effects of Malirid Ds include headache, nausea, dizziness, vomiting, loss of appetite, and abdominal pain.

Is Malirid Ds safe to take during pregnancy?

Malirid Ds should not be used during pregnancy, as it can cause harm to the unborn baby.

Is Malirid Ds safe for children?

Malirid Ds is generally not recommended for use in children under the age of 16.

Does Malirid Ds interact with other medications?

Yes, Malirid Ds can interact with other medications, including antacids, antibiotics, antivirals, and nonsteroidal anti-inflammatory drugs (NSAIDs).

What is the recommended dosage of Malirid Ds?

The recommended dosage of Malirid Ds is 0.5-1 tablet per day for adults and 0.25-0.5 tablet per day for children aged 16 and over.

What is the difference between Malirid Ds and chloroquine?

Malirid Ds is an antimalarial medication used to treat and prevent malaria infections, while chloroquine is an antimalarial medication used to treat and prevent malaria infections and also reduce inflammation in some autoimmune diseases.

Does Malirid Ds need to be taken with food?

It is recommended to take Malirid Ds with food to reduce the risk of stomach upset.

What should I do if I miss a dose of Malirid Ds?

If you miss a dose of Malirid Ds, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and take your next dose at the regular time.

How long should I take Malirid Ds?

The length of time that Malirid Ds should be taken depends on your individual medical condition. Your doctor will advise you on how long to take the medication.

Can I drink alcohol while taking Malirid Ds?

It is not recommended to drink alcohol while taking Malirid Ds, as it may increase the risk of side effects.

What is the generic name for Malirid Ds?

The generic name for Malirid Ds is primaquine phosphate.

Is Malirid Ds an antibiotic?

No, Malirid Ds is not an antibiotic; it is an antimalarial medication.

Can I buy Malirid Ds over the counter?

No, Malirid Ds is a prescription-only medication and cannot be bought over the counter.

Can Malirid Ds be used to treat other conditions?

No, Malirid Ds is only used to treat and prevent malaria infection.

What is the price of Malirid Ds?

The price of Malirid Ds varies depending on the manufacturer and dosage. Your pharmacy can provide you with the most up-to-date pricing information.

Can Malirid Ds cause liver damage?

Yes, Malirid Ds can cause liver damage in some individuals. If you have any liver problems, speak to your doctor before taking Malirid Ds.

Does Malirid Ds cause drowsiness?

Yes, Malirid Ds can cause drowsiness in some individuals. If you experience drowsiness, do not drive or operate machinery.

Does Malirid Ds interact with birth control?

Yes, Malirid Ds can interact with birth control. It is recommended to use another form of birth control while taking Malirid Ds.

Does Malirid Ds cause diarrhea?

Yes, Malirid Ds can cause diarrhea in some individuals.

Is Malirid Ds used to treat malaria?

Yes, Malirid Ds is used to treat and prevent malaria infection.

Does Malirid Ds cause weight gain?

No, Malirid Ds does not typically cause weight gain.

Can I take Malirid Ds with other medications?

It is important to tell your doctor about any other medications you are taking before taking Malirid Ds, as some medications can interact with Malirid Ds.

Will Malirid Ds work against all strands of malaria?

Malirid Ds has been shown to be effective against most strains of malaria; however, it may not work against all strains.

Does Malirid Ds cause loss of appetite?

Yes, Malirid Ds can cause loss of appetite in some individuals.

When should I start taking Malirid Ds?

Your doctor will advise you as to when you should start taking Malirid Ds. It is typically recommended to start taking the medication 1-2 days prior to traveling to a malaria-endemic region.

Is Malirid Ds safe to take if I have kidney problems?

Yes, Malirid Ds is generally considered safe to take if you have kidney problems; however, your doctor may need to adjust the dose or monitor your condition more closely.

Can I take Malirid Ds if I have high blood pressure?

Yes, Malirid Ds can be taken if you have high blood pressure; however, your doctor may need to adjust the dose or monitor your condition more closely.

Can I take Malirid Ds for longer than the recommended time?

No, Malirid Ds should only be taken for the recommended time, as it can cause serious side effects if taken for longer than recommended.

Can Malirid Ds be split in half?

Yes, Malirid Ds tablets can be safely split in half in order to reduce the dose taken.

What are the symptoms of an overdose on Malirid Ds?

Symptoms of an overdose on Malirid Ds may include headache, nausea, dizziness, vomiting, and abdominal pain.

Can Malirid Ds cause an allergic reaction?

Yes, Malirid Ds can cause an allergic reaction in some individuals. Stop taking the medication and seek medical attention if you experience any symptoms of an allergic reaction, such as rash, itching, or swelling.

Is Malirid Ds effective against Plasmodium falciparum malaria?

Yes, Malirid Ds has been found to be effective against Plasmodium falciparum malaria.

Does Malirid Ds cause hair loss?

No, Malirid Ds does not typically cause hair loss.

Can I take Malirid Ds if I'm breastfeeding?

No, Malirid Ds should not be taken while breastfeeding, as it can pass into breast milk and cause harm to the baby.

Does Malirid Ds need to be taken with food?

It is recommended to take Malirid Ds with food to reduce the risk of stomach upset.

What should I do if I get an upset stomach while taking Malirid Ds?

If you experience an upset stomach while taking Malirid Ds, try taking the medication with food. If your symptoms persist, speak to your doctor.

Does Malirid Ds cause drowsiness?

Yes, Malirid Ds can cause drowsiness in some individuals. If you experience drowsiness, do not drive or operate machinery.

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