Lodivas
Lodivas Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Lodivas is a brand name. Its generic name is Amlodipine + Valsartan.
Introduction
Lodivas is an antihypertensive medication that is used to treat hypertension. It is a combination of the calcium channel blocker Amlodipine and the angiotensin II receptor blocker Valsartan.Uses for
Lodivas is used to treat mild or moderate hypertension by lowering blood pressure and preventing associated complications such as stroke and cardiovascular disease.Mechanism Of Action
Lodivas works by blocking calcium channels in the blood vessels, causing them to relax and decrease blood pressure. Valsartan blocks the action of Angiotensin II, which normally causes the narrowing of certain blood vessels, and decreases blood pressure. Valsartan also increases the amount of circulating blood volume.How Long Does It Take To Work
The effects of Lodivas can be seen within two weeks of taking the medication, and it will normally reach its full effect within four to eight weeks.Absorption
Amlodipine is readily absorbed from the gastrointestinal tract and reaches maximal levels within 2 to 4 hours. Valsartan is also absorbed rapidly and peak effects occur 1-2 hours after administration.Route Of Elimination
Lodivas is eliminated partly by the kidneys and partly by the intestines.Dosage
The recommended adult starting dose of Lodivas is amlodipine 5mg/valsartan 160 mg once a day with or without food. Dosage may be increased as necessary. Maximum recommended dose is amlodipine 10mg/valsartan 320mg once a day.Administration
Lodivas should be taken orally with or without food once daily. Swallow the tablet whole and do not chew or break it.Side Effects
Side effects of Lodivas may include headache, dizziness, fatigue, nausea, abdominal pain, diarrhea.Toxicity
Lodivas is not considered toxic. However, the maximum daily recommended dose should not be exceeded and it should not be taken with grapefruit or grapefruit juice.Precautions
Patients using Lodivas should be monitored for any signs or symptoms of fluid accumulation, such as swelling of the ankles or feet, or shortness of breath. Patient should also inform their provider if they have a history of liver or kidney disease, heart disease, or if they have been prescribed diuretics.Interactions
Lodivas can interact with other medications, such as diuretics, angiotensin-converting enzyme inhibitors, potassium-sparing diuretics, potassium supplements, and birth control pills.Disease Interactions
Lodivas should not be used in patients with anuria, aortic stenosis, or severe hepatic impairment.Drug Interactions
Lodivas can interact with other drugs, such as diuretics, angiotensin-converting enzyme inhibitors, potassium-sparing diuretics, potassium supplements, and birth control pills.Food Interactions
Lodivas should not be taken with grapefruit or grapefruit juice, as grapefruit may interfere with the absorption of the medication.Pregnancy Use
Lodivas should not be used during pregnancy unless the benefit outweighs the risk.Lactation Use
Lodivas is not recommended for use in nursing mothers.Acute Overdoses
Patients who have taken an overdose of Lodivas should seek medical help as soon as possible. Symptoms of overdose may include hypotension, dizziness, and confusion.Contraindication
Lodivas is contraindicated in patients with anuria, aortic stenosis, or severe hepatic impairment.Use Direction
Lodivas should be taken once daily as prescribed by your doctor. Take the medication with or without food. Swallow the medicine whole, do not chew or break it.Storage Condition
Lodivas should be stored at room temperature and in a tight, light-resistant container.Volume Of Distribution
Amlodipine+Valsartan has a volume of distribution of 118L.Half Life
Amlodipine has a half-life of approximately 75 hours and Valsartan has a half-life of approximately 6 hours.Clearance
Amlodipine+Valsartan is eliminated mainly by cytochrome P450 enzyme system in the liver, with a smaller portion excreted unchanged in the urine.Here you find in details version of Lodivas
Some Frequently Asked Questions About Lodivas
What is Lodivas?
Lodivas is a combination medicine used to treat high blood pressure (hypertension). It contains two different medicines which help lower blood pressure: amlodipine and valsartan. Amlodipine is a calcium channel blocker that works by relaxing the muscles in your blood vessels to help lower your blood pressure. Valsartan is an angiotensin II receptor blocker that works by blocking the action of certain chemicals in your body that tighten your blood vessels, causing your blood pressure to go up.
How do I take Lodivas?
Lodivas should be taken as prescribed by your doctor. The usual starting dose for adults is 5 mg/160 mg, taken once daily. Your doctor may increase your dose if needed.
What are the possible side effects of Lodivas?
Common side effects include dizziness, headache, low blood pressure, fatigue, nausea, diarrhea, muscle cramps, and decreased heart rate. Less common side effects can include skin rash, joint pain, increased urination, decreased kidney function, chest pain, and heart failure. Talk to your doctor if you experience any of these side effects while taking Lodivas.
What should I do if I forget to take Lodivas?
If you miss a dose, take it as soon as you remember. If it is close to the time of the next dose, skip the missed dose and take your next dose at the regular time. Do not take a double dose of Lodivas.
Can I take Lodivas while pregnant?
It is not recommended that you take Lodivas while pregnant. Talk to your doctor if you are pregnant or planning to become pregnant while taking Lodivas.
Can I take Lodivas with other medications?
It is important to tell your doctor about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medications can interact with Lodivas and affect how it works, so let your doctor know about all the medications you take.
What should I know before taking Lodivas?
Before taking Lodivas, tell your doctor about all your medical conditions, including if you have a history of heart problems, kidney disease, liver disease, are pregnant or planning to become pregnant, or if you are breastfeeding. Also tell your doctor about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Should I avoid taking other medications with Lodivas?
No, however it is important to tell your doctor about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medications can interact with Lodivas and affect how it works, so your doctor needs to know about all the medications you take.
Does Lodivas cause weight gain?
Weight gain has been reported in people taking Lodivas. Tell your doctor if you are experiencing any changes in your weight while taking Lodivas.
Is Lodivas safe to take for a long time?
Lodivas is generally safe to take for a long time, however, it is important to talk to your doctor about any risks or concerns you may have. Your doctor will be able to discuss the benefits and risks for you.
Should I take Lodivas in the morning or at night?
Lodivas can be taken either in the morning or at night. It is best to take the medication at the same time each day to keep a consistent level in your blood. Talk to your doctor about the best time for you to take Lodivas.
What are the common side effects of Lodivas?
Common side effects include dizziness, headache, low blood pressure, fatigue, nausea, diarrhea, muscle cramps, and decreased heart rate. Less common side effects can include skin rash, joint pain, increased urination, decreased kidney function, chest pain, and heart failure. Talk to your doctor if you experience any of these side effects while taking Lodivas.
What should I do if I experience side effects from Lodivas?
If you experience any side effects from Lodivas, talk to your doctor or pharmacist. They may be able to adjust your dose or suggest alternatives. It is also important to tell your doctor about any other medications you are taking, as they can also cause side effects.
Can I drink alcohol while taking Lodivas?
Alcohol can increase the side effects of Lodivas. It is best to talk to your doctor about drinking alcohol while taking this medicine. If you decide to drink, do so in moderation.
Can I take a diuretic with Lodivas?
A diuretic may be taken with Lodivas if needed. Your doctor will be able to determine if a diuretic is necessary for your condition.
Are there any other medications I should avoid while taking Lodivas?
There are certain medications that should be avoided while taking Lodivas, including other angiotension-converting enzyme (ACE) inhibitors, angiotension-II receptor blockers (ARBs), calcium channel blockers (CCBs), potassium-sparing diuretics, trimethoprim-sulfamethoxazole, and non-steroidal anti-inflammatory drugs (NSAIDs). Check with your doctor or pharmacist to make sure your medications are safe to take with Lodivas.
What should I do if I experience an allergic reaction to Lodivas?
If you experience any signs of an allergic reaction, including hives, itching, skin rash, difficulty breathing, or swelling of your face, lips, tongue, or throat, seek medical attention immediately. Stop taking Lodivas and tell your doctor right away.
What happens if I overdose on Lodivas?
If you think you or someone else has overdosed on Lodivas, call 911 or your local poison control center right away. Symptoms of an overdose may include severe dizziness, slow heartbeat, confusion, difficulty breathing, and fainting.
Are there any foods or drinks I should avoid while taking Lodivas?
Alcohol and caffeine can increase the side effects of Lodivas. Avoid drinking large amounts of caffeine-containing beverages (e.g., coffee, tea, cola) or alcohol while you are taking this medication. Talk to your doctor about your diet and medications, as certain foods may interact with them.
Can Lodivas be used to treat other conditions?
Lodivas is mostly used to treat high blood pressure (hypertension). It may be used off-label to treat other conditions, however, only your doctor can determine if this is appropriate for your condition. Speak with your doctor about any other conditions you may have and if Lodivas is an appropriate treatment.
Will Lodivas help lower my blood pressure?
Lodivas is used to treat high blood pressure (hypertension). This medication can help lower your blood pressure over time. Follow your doctor's instructions and report any changes in your blood pressure to your doctor.
How quickly will I notice a difference after taking Lodivas?
The effects of Lodivas may take several weeks to become evident. You may begin to notice a lower blood pressure within a few weeks. Your doctor can monitor your blood pressure during treatment and adjust your dose if necessary.
Can I take Lodivas if I have a history of heart problems?
Lodivas can be used for people with a history of heart problems, however, your doctor may adjust your dose or use other medications to help control your symptoms. Your doctor will be able to determine the best treatment plan for you.
Will I need to have regular blood tests while taking Lodivas?
You may need to have regular blood tests while taking Lodivas. Your doctor will be able to determine if regular blood tests are necessary. Tell your doctor if you experience any changes in your blood pressure while taking Lodivas.
Can I take other medications with Lodivas?
It is important to tell your doctor about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medications can interact with Lodivas and affect how it works, so let your doctor know about all the medications you take.
What should I do if I experience dizziness while taking Lodivas?
Dizziness is a common side effect of Lodivas. If you experience dizziness while taking this medication, contact your doctor. Avoid driving, operating machinery, or performing other hazardous activities until the dizziness passes.
Should I take Lodivas with food?
Lodivas can be taken with or without food. It is best to take the medication at the same time each day to keep a consistent level in your blood. Talk to your doctor about the best time for you to take Lodivas.
Can Lodivas be used to treat heart failure?
Lodivas may be used off-label to treat certain conditions, such as heart failure. Your doctor will be able to determine if this is an appropriate treatment for your condition.
Can Lodivas be used in children?
Lodivas is not indicated for use in children. Consult your doctor if you are considering treating a child with this medication.
Does Lodivas lower cholesterol?
Lodivas does not directly lower cholesterol. However, lower blood pressure can help improve cholesterol levels. If you are looking to lower your cholesterol, it is important to talk to your doctor about lifestyle changes, medications, and other treatments.
Does Lodivas cause hair loss?
Hair loss is not a common side effect of Lodivas. However, it has been reported in some people taking this medication. Talk to your doctor if you experience any changes in your hair while taking this medication.