Lidocaine-Prilocaine-Cream Base

Lidocaine-Prilocaine-Cream Base Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Lidocaine-Prilocaine-Cream Base is a brand name. Its generic name is Lidocaine Hydrochloride + Prilocaine.

Introduction

Lidocaine Hydrochloride and Prilocaine (LHP) is a topical anesthetic combination available as a cream used to reduce pain caused by minor skin irritations, itching, burning, and insect bites. It works by blocking nerve signals in the affected area and numbing it.

Uses For

LHP is used to reduce the pain associated with minor skin irritations, itching, burning, and insect bites. It is also used before certain minor medical procedures like dermabrasion, skin biopsies, and vein punctures.

Mechanism of Action

LHP acts by blocking nerve signals in the area where it is applied. It is a topical anesthetic, meaning that it numbs the area where it is applied without affecting the rest of the body.

How Long Does It Take To Work?

LHP starts to work within minutes of application. Pain relief usually starts within 5-10 minutes of application.

Absorption

LHP is absorbed into the skin when applied. It is also absorbed by local tissues and passes from the applied area into the rest of the body.

Route of Elimination

LHP is metabolized by the liver and then eliminated in urine, which is why it is necessary to avoid drinking alcohol or taking other drugs before and after using LHP.

Dosage

LHP is available as a cream, gel, or patch. The dosage and duration of treatment may vary depending on the type, strength, and age of the person. For adults, the LHP cream or gel contains 5% lidocaine and 2.5% prilocaine, and is typically applied 3-4 times daily for up to 7 days. The patch contains 20% lidocaine and 7% prilocaine, and is typically applied once per day for a maximum of 7 days. For pediatric use, the dose of LHP cream or gel should be adjusted according to the weight of the child.

Administration

LHP is usually applied topically to the affected area. The cream or gel can be applied directly to the skin up to 4 times per day, or as prescribed by a physician. The patch should be applied to an unbroken and intact area of skin and should not be used for more than 7 days in total.

Side Effects

The most common side effects of LHP are skin irritation, burning, and stinging. Other less common side effects may include nausea, headaches, dizziness, drowsiness, and seizures.

Toxicity

LHP is generally considered safe when used as directed. Overdose can occur if too much of the medicine is applied to the skin or if the patches are left on for too long. Overdose can lead to serious side effects and should be treated immediately by a physician.

Precaution

Before using LHP, be sure to talk to your doctor about any allergies or medical conditions you may have. Do not use the product on broken skin, and it should not be used if you have a known sensitivity to lidocaine or prilocaine. Do not use LHP if you are pregnant, breastfeeding, or planning to become pregnant.

Interaction

Before using LHP, be sure to tell your doctor about any medications, supplements, or herbal remedies you are taking. Certain medications, such as MAO inhibitors, should not be used with LHP.

Disease Interaction

LHP may interact with certain diseases or medical conditions. This includes any serious skin irritation, porphyria, and liver or kidney disease. Be sure to tell your doctor if you have any of these conditions before using this product.

Drug Interaction

LHP may interact with certain drugs, such as MAO inhibitors, medicines for diabetes, or medicines that affect your blood pressure or heart rhythm. Be sure to tell your doctor about any other medications you are taking before using this product.

Food Interactions

LHP may interact with certain foods, such as dairy and citrus products. Be sure to tell your doctor if you are allergic to any foods before using this product.

Pregnancy Use

LHP is not recommended for use during pregnancy. This is because it is absorbed by the skin and passes into the bloodstream, and it is not known if it has any effects on the developing fetus.

LactationUse

LHP is not recommended for use while breastfeeding. This is because it is absorbed by the skin and passes into the mother's milk, and it is not known if it has any effects on the infant.

Acute Overdose

If an overdose of LHP occurs, it is important to seek medical attention immediately. Overdose symptoms may include seizures, difficulty breathing, nausea, irregular heart rate, and low blood pressure.

Contraindication

LHP should not be used in people who are allergic to lidocaine or prilocaine, or who have a known sensitivity to either ingredient. It should also not be used on broken skin, or in areas where there is an infection.

Use Direction

LHP cream or gel should be applied to the affected area as directed. For adults, it is typically applied 3-4 times per day for up to 7 days of treatment. For pediatric use, the dose should be adjusted according to the weight of the child. The patch should be applied to an intact area of skin and should not be used for more than 7 days.

Storage Condition

LHP should be stored at room temperature in a dry place and away from direct light, heat, and moisture. Keep it out of reach of children and pets. Do not freeze.

Volume of Distribution

The volume of distribution for LHP is not known.

Half-Life

The half-life of LHP is not known.

Clearance

The clearance rate for LHP is not known.

Here you find in details version of Lidocaine-Prilocaine-Cream Base

Some Frequently Asked Questions About Lidocaine-Prilocaine-Cream Base