Levoride
Levoride Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Levoride is a brand name. Its generic name is Levosulpiride.
Introduction
Levoride is a dopamine D2 antagonist used in the treatment of functional gastrointestinal disorders like gastritis, intestinal colic, dyspepsia, and irritable bowel syndrome. It is commonly used with ppis like lansoprazole and rabeprazole.Uses For
Levoride is used for the treatment of functional gastrointestinal disorders like gastritis, intestinal colic, dyspepsia, and irritable bowel syndrome. It is used in combination with proton pump inhibitors (PPIs). It is also used to treat symptoms of drug-induced extrapyramidal dysfunction including parkinsonian syndrome.Mechanism of Action
Levoride works by blocking the action of dopamine at D2 receptors in the gut and the brain. By blocking dopamine, it reduces the symptoms of gastric acid reflux and ulcers, as well as symptoms of parkinsonism caused by certain drugs.How Long Does It Take to Work?
Levoride usually starts to take effect within 2 - 4 hours and peak effectiveness can be seen within 8 - 12 hours.Absorption
Levoride is rapidly and completely absorbed from the gastrointestinal tract.Route of Elimination
Levoride is eliminated mainly in the urine, with only a small amount eliminated in the faeces.Dosage
The dosage of levosulpiride depends on the condition being treated and the individual patient characteristics. The recommended starting dosage is 25 mg two times daily. The dosage may be increased depending on the response. The maximum dosage is 75 mg/day.Administration
Levoride should be taken orally, preferably with a meal.Side Effect
The most common side effects associated with levosulpiride use are dry mouth, constipation, headache, weight gain, and fatigue.Toxicity
Levoride is generally very safe, however, long-term use is associated with drowsiness, confusion, and restlessness.Precaution and Interaction
Levoride should be used with caution in people with cardiac disease, renal failure, or liver failure, as it can worsen these conditions. Levoride should not be used with psychiatric medications, as it may increase the risk of psychotic symptoms.Drug and Disease Interactions
The use of levosulpiride with certain medications, like antipsychotics, levodopa, and tricyclic antidepressants, can result in increased effects or side effects. Levoride should be used with caution in people with Parkinson's disease or renal disease, as it can worsen these conditions.Food Interactions
Levoride should be taken with a meal or at least immediately after a meal for optimal absorption.Pregnancy and Lactation Use
Levoride should not be used during pregnancy or lactation as it can cause adverse effects in the fetus and nursing infant.Acute Overdose
Symptoms of overdose include restlessness, tremor, hypotension, collapse, coma, and death.Contraindication
Levoride is contraindicated in people with hypersensitivity to the drug and those with hepatic impairment.Use Direction
Levoride should be taken orally, preferably with a meal. The dosage should be gradually increased as directed by the prescribing doctor, and maximum daily dosage should not exceed 75 mg per day.Storage Condition
Levoride should be stored at room temperature, away from direct sunlight and moisture.Volume of Distribution
The volume of distribution for levosulpiride is 0.7 - 0.8 L/kg.Half Life
The half-life of levosulpiride is 2 - 3 hours.Clearance
The clearance of levosulpiride is 0.7 - 0.8 L/h/kg.Here you find in details version of Levoride
Some Frequently Asked Questions About Levoride
What is Levoride?
Levoride is a medication used to help reduce or control the symptoms of gastrointestinal problems, such as stomach pain, constipation, and irritable bowel syndrome.
What is the mechanism of action of Levoride?
Levoride works by stimulating the release of dopamine, a neurotransmitter which can help to reduce nausea,relieve pain and reduce muscle spasms in the gastrointestinal tract.
Who should not take Levoride?
Levoride is not recommended for pregnant women or those with a history of seizures or extreme sensitivity to other similar medications. Furthermore, patients that are taking drugs such as MAO (monoamine oxidase inhibitors) should not take Levoride.
What are the side effects of Levoride?
The most common side effects of Levoride include drowsiness, dizziness, headache, dry mouth, constipation, nausea, and increased blood pressure.
How should Levoride be stored?
Levoride should be stored in a cool, dry place, away from direct light and moisture. It should also be kept out of reach of children and pets.
How long does it take for Levoride to take effect?
The effects of Levoride will typically start to become apparent within 1 hour, but may take up to 3 hours to reach full effect.
Is Levoride safe to use for long-term treatment?
Levoride is considered safe to use for long-term treatment of gastrointestinal disorders. Studies have shown that long-term use does not lead to any unfavorable effects.
Does Levoride interact with any other medications?
Yes, Levoride can interact with some other medications. It is important to tell your doctor about all the other medications you are taking before starting treatment with Levoride.
Can I take Levoride with alcohol?
No, it is recommended that Levoride not be taken with alcohol, as the combination may lead to drowsiness and increased risk of side effects.
Does Levoride cause addiction?
No, Levoride is not known to be addictive.
Is Levoride available over-the-counter?
No, Levoride is only available through a prescription from a doctor.
Does Levoride cause weight gain?
No, Levoride is not known to cause weight gain.
What is the dosage for Levoride?
The dosage of Levoride will depend on the individual patient's medical condition, age, and weight. Your doctor will be able to recommend the appropriate dose for your case.
Does Levoride reduce stomach acid levels?
No, Levoride does not reduce stomach acid levels, but can help to reduce the effects of acidic stomach contents.
Can Levoride be used to treat gastroesophageal reflux disease (GERD)?
Yes, Levoride can be used to help reduce the symptoms of gastroesophageal reflux disease (GERD).
Are there any herbs or supplements that could interact with Levoride?
Yes, certain herbs and supplements, such as St. John's Wort, can interact with Levoride, so it is important to tell your doctor about any herbs or supplements you are taking before starting treatment with Levoride.
What is the usual duration of treatment with Levoride?
The duration of treatment with Levoride will depend on the individual patient and the severity of their medical condition. Generally, treatment with Levoride should not exceed 16 weeks.
Is Levoride safe to use in elderly patients?
Yes, Levoride is considered safe to use in elderly patients.
Is Levoride safe to use in children?
Levoride is not recommended to be used in children below the age of 18.
What should I do if I miss a dose of Levoride?
If you miss a dose of Levoride, take it as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule.
What should I do if I overdose on Levoride?
If you or someone else has overdosed on Levoride, seek immediate medical attention. Common overdose symptoms include drowsiness, confusion, nausea, vomiting, rapid heart rate, and shallow breathing.
Can Levoride be used to treat anxiety?
No, Levoride is not recommended to be used to treat anxiety, as it is not known to have any therapeutic effect on anxiety.
Can Levoride be used to treat depression?
No, Levoride is not recommended to be used to treat depression, as it is not known to have any therapeutic effect on depression.
Can I take Levoride while breastfeeding?
Levoride is not recommended to be used by breastfeeding mothers, as it may be detectable in the mother's milk, and could potentially be passed on to the baby.
Can Levoride be used to treat any other medical conditions?
Levoride is only recommended to be used to treat gastrointestinal problems such as stomach pain, constipation, and irritable bowel syndrome. It is not recommended to be used for any other medical conditions.
What should I do if I experience any side effects while taking Levoride?
If you experience any side effects while taking Levoride, contact your doctor or pharmacist. Do not stop taking the medication, as this could worsen your condition.
Can Levoride be used to treat Parkinson’s disease?
No, Levoride is not recommended to be used to treat Parkinson’s disease.
Can Levoride cause tardive dyskinesia?
Tardive dyskinesia is a rare but serious neurological disorder that is caused by long-term use of certain antipsychotic medications. There is no evidence suggesting that Levoride can cause tardive dyskinesia.
Is Levoride available as a generic drug?
No, Levoride is not available as a generic drug.
Does Levoride interact with other antipsychotic medications?
Yes, Levoride can interact with other antipsychotic medications, such as haloperidol. It is important to tell your doctor about all other medications you are taking before starting treatment with Levoride.
Is Levoride effective in treating nausea and vomiting?
Yes, Levoride has been shown to be effective in reducing the symptoms of nausea and vomiting.
Can Levoride be used to treat gastroenteritis?
Yes, Levoride can be used to help reduce the symptoms of gastroenteritis such as nausea, vomiting, stomach pain, and diarrhea.
Is Levoride safe to use in liver disease or kidney disease?
Levoride should be used with caution in patients with liver or kidney disease, as it may aggravate certain symptoms or cause problems with the elimination of the medication from the body.
Can Levoride be used to treat seizures?
No, Levoride is not recommended to be used to treat seizures.
Can Levoride be used to treat migraine headaches?
No, Levoride is not recommended to be used to treat migraine headaches.
Does Levoride cause drowsiness?
Yes, Levoride can cause drowsiness, so caution should be taken when operating machinery or driving.
Can Levoride be used to treat IBS-C?
Yes, Levoride has been shown to be effective in reducing the symptoms of irritable bowel syndrome with constipation (IBS-C).
Can Levoride be used to treat IBS-D?
Yes, Levoride has been shown to be effective in reducing the symptoms of irritable bowel syndrome with diarrhea (IBS-D).
Does Levoride cause insomnia?
Levoride may cause insomnia in some patients, although this is not a common side effect.
Can Levoride be used to treat gastroparesis?
Yes, Levoride has been shown to be effective in reducing the symptoms of gastroparesis.
Can Levoride be used to treat ulcers?
Levoride can help to reduce the symptoms of peptic ulcers, but it is not recommended to be used as the sole treatment for ulcers.
Does Levoride cause withdrawal symptoms?
Levoride does not usually cause withdrawal symptoms when treatment is stopped.