K Stryn
K Stryn Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? K Stryn is a brand name. Its generic name is Calcium Polystyrene Sulfonate.
Introduction
K Stryn (CPS) is an ion-exchange resin used as a salt of polystyrene sulfonic acid or sodium polystyrene sulfonate mainly for the treatment of hyperkalemia and other electrolyte imbalances.Uses
K Stryn is most commonly used to treat hyperkalemia, which is a condition characterized by abnormally high levels of potassium in the blood. It is also used to treat diarrhea, gut inflammation, constipation, and overdose of medications such as lithium and digoxin.Mechanism of Action
CPS works by exchanging calcium ions for potassium ions in the blood, helping to reduce the concentration of potassium and balance electrolyte levels. The calcium also helps to reabsorb fluid to reduce gastrointestinal irritation that may be caused by too much potassium.How Long Does it Take to Work?
Calcium polystyrene sulfonate typically starts to work within 1-2 hours of administration, although maximum effects of the drug may take up to 4-6 hours.Absorption
Calcium polystyrene sulfonate is not absorbed by the body or metabolized and is excreted unchanged through the feces.Route of Elimination
Calcium polystyrene sulfonate is eliminated through the feces as it is not absorbed by the body.Dosage
Calcium polystyrene sulfonate is typically administered orally. Generally, it is recommended to start with a dose of 6-10 grams per day in children and 10-15 grams per day in adults, given 3-4 divided doses. Alternatively, the fibers can be put into a container filled with liquid and ingested as a suspension.Administration
Calcium polystyrene sulfonate may be given orally or by enema. When given orally, the fibers should be dispersed in a glass of liquid, such as water or juice, to prevent them from clumping together. If administered by enema, the fibers must be suspended in a solution of water and sodium bicarbonate or a phosphate buffer.Side Effects
Common side effects of calcium polystyrene sulfonate include nausea, vomiting, diarrhea, constipation, stomach upset, gas, bloating, and dry mouth. Rare side effects may include rash, itching, hives, difficulty breathing, tightness in the chest, facial swelling, and anaphylaxis.Toxicity
In general, there is a low risk of toxicity associated with calcium polystyrene sulfonate. Severe toxicity is extremely rare.Precautions
Patients with kidney disease, bowel obstruction, or difficulty taking oral medications should not use calcium polystyrene sulfonate. In addition, calcium polystyrene sulfonate should not be used in patients who are allergic to polystyrene sulfonate, sulfonates, or other related medications.Interaction
Calcium polystyrene sulfonate may interact with certain drugs, such as lithium or digoxin. Therefore, it is important to tell your doctor about any other medications you are taking before starting treatment with CPS.Disease Interaction
Calcium polystyrene sulfonate may interact with certain diseases, such as kidney disease or bowel obstruction. Therefore, it is important to tell your doctor about any existing medical conditions before starting treatment with CPS.Drug Interactions
Calcium polystyrene sulfonate may interact with certain drugs, such as lithium or digoxin. Therefore, it is important to tell your doctor about any other medications you are taking before starting treatment with CPS.Food Interactions
Calcium polystyrene sulfonate does not interact with food. It is recommended to take the medication with a full glass of water and to avoid taking antacids, laxatives, or other drugs within 4 hours of taking calcium polystyrene sulfonate.Pregnancy Use
Due to a lack of adequate studies in pregnant women, the use of Calcium polystyrene sulfonate should be avoided during pregnancy.Lactation Use
Due to a lack of adequate studies in nursing women, the use of Calcium polystyrene sulfonate should be avoided during lactation.Acute Overdose
An acute overdose of calcium polystyrene sulfonate is unlikely to cause serious harm, however, it may lead to GI discomfort and constipation. Patients experiencing overdose symptoms should be evaluated by a healthcare provider.Contraindication
Calcium polystyrene sulfonate should not be used in patients who are allergic to polystyrene sulfonate, sulfonates, or other related medications. It should also not be used in patients with kidney disease, bowel obstruction, or difficulty taking oral medications.Use Directions
Calcium polystyrene sulfonate should be taken according to your doctor’s instructions. The fibers should be dispersed in a glass of liquid, such as water or juice, to prevent clumping. Alternatively, the fibers can be put into a container filled with liquid and ingested as a suspension. Take the medication with a full glass of water and avoid taking antacids, laxatives, or other drugs within 4 hours of taking calcium polystyrene sulfonate. It is important to take the medication on a regular schedule to ensure effectiveness.Storage Conditions
Calcium polystyrene sulfonate should be stored at room temperature away from direct light, heat, and moisture. It should be kept in the container it came in and should not be used after the expiration date on the label.Volume of Distribution
Calcium polystyrene sulfonate is not absorbed from the gastrointestinal tract and therefore has no volume of distribution.Half Life
Calcium polystyrene sulfonate has a half-life of approximately one hour due to its rapid excretion through the feces.Clearance
Calcium polystyrene sulfonate is not susceptible to metabolism and therefore has no clearance.Here you find in details version of K Stryn