Juliperla

Juliperla Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Juliperla is a brand name. Its generic name is Ethinylestradiol + Gestodene.

Introduction

Juliperla is a combination of two hormones commonly used as a contraceptive drug. Ethinylestradiol is an estrogen hormone and Gestodene is a progestogen hormone. It works primarily by preventing ovulation and the change of the cervix mucosa to increase difficulty of sperm entrance.

Uses

Juliperla is used primarily as a form of contraception to prevent pregnancy but can also be used to treat some secondary symptoms in other conditions such as acne, endometriosis, hirsutism, and polycystic ovary syndrome.

Mechanism Of Action

Juliperla works primarily by preventing ovulation through inhibiting the secretion of gonadotropin-releasing hormone, which in turn stops the release of luteinizing hormone and follicle-stimulating hormone. Additionally, it thickens the cervical mucus, which increases difficulty for sperm to reach and fertilize a woman's egg.

How Long Does It Take To Work?

Juliperla takes 7 days to achieve maximum effectiveness. If used as instructed, Juliperla can provide reliable contraception.

Absorption

When taken orally, Juliperla is absorbed quickly and efficiently from the intestine into the bloodstream. The majority of the hormones are stored in the adipose tissue (fat tissue).

Route Of Elimination

Juliperla is eliminated from the body in a number of ways. It is metabolized in the liver and excreted from the body in the urine and feces, as well as through the exhalation of breath.

Dosage

The dose of Juliperla depends on the patient's medical condition, age, weight, and response to treatment. It typically ranges from 50 and 75 mcg of each hormone. The drug is usually taken once daily for 21 days of the menstrual cycle, followed by a 7-day break before the next cycle begins.

Administration

Juliperla is taken orally, usually in the form of a tablet. It should be taken at around the same time each day.

Side Effect

Common side effects of Juliperla may include nausea, headache, weight gain, breast tenderness, and irregular period.

Toxicity

When taken as indicated, Juliperla is not toxic. However, overdoses of Juliperla may occur in rare cases and can lead to serious adverse effects.

Precaution

Patients taking Juliperla should avoid smoking and taking certain medications including antibiotics, antifungals, and anti-epileptic drugs. Additionally, patients should keep regular appointments with their healthcare provider.

Interaction

Juliperla interacts with a number of drugs, such as antibiotics, antifungals, anti-epileptics, and high-dose corticosteroids. It is important that patients taking this medication discuss any other medications they are taking with their healthcare provider.

Disease Interaction

Juliperla may interact with certain diseases such as hypertension, diabetes, liver disease, and heart disease. Patients should discuss any existing medical conditions with your healthcare provider before taking this medication.

Drug Interaction

Patients taking Juliperla should avoid certain drugs as they may interact with the medication and diminish its effectiveness or cause adverse effects. Such drugs include antibiotics, antifungals, anti-epileptic drugs, and high-dose corticosteroids.

Food Interaction

There are no known food interactions to be aware of while taking Juliperla, however, it is important to take the medication as directed.

Pregnancy Use

Juliperla is not recommended for use during pregnancy due to the risks it poses to the developing fetus.

Lactation Use

It is not recommended to take this medication while breastfeeding as it can increase the risk of side effects in the nursing infant.

Acute Overdose

Signs and symptoms of an acute Juliperla overdose may vary from patient to patient but may include nausea, vomiting, dizziness, headache, and irregular heartbeat. If an overdose is suspected, seek medical attention immediately.

Contraindication

Juliperla should not be used by patients with a history of heart disease, stroke, blood clots, liver disease, or uncontrolled high blood pressure. Additionally, it is not recommended for patients with uncontrolled diabetes or in women who are breastfeeding.

Use Direction

Juliperla should be taken as directed by your healthcare provider. Patients should take a pill once daily at the same time each day for 21 days of the menstrual cycle, followed by a 7-day break before the next cycle begins.

Storage Condition

Juliperla should be stored at room temperature away from moisture, heat, and light.

Volume of Distribution

Juliperla has a volume of distribution of approximately 6 liters per kilogram.

Half Life

The half-life of Juliperla is approximately 36 hours for ethinylestradiol and 117 hours for gestoden.

Clearance

Juliperla has a clearance of 1.6 liters/hr/kg for ethinylestradiol and 0.17 liters/hr/kg for gestodene.

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